Publications

2024 Publications

Adolph, C., Cheung, C.-Y., McNeil, M. B., Jowsey, W. J., Williams, Z. C., Hards, K., Harold, L. K., Aboelela, A., Bujaroski, R. S., Buckley, B. J., Tyndall, J. D. A., Li, Z., Langer, J. D., Preiss, L., Meier, T., Steyn, A. J. C., Rhee, K. Y., Berney, M., Kelso, M. J., & Cook, G. M. (2023). A dual-targeting succinate dehydrogenase and F1Fo-ATP synthase inhibitor rapidly sterilizes replicating and non-replicating Mycobacterium tuberculosis. Cell Chemical Biology, S2451945623004324. https://doi.org/10.1016/j.chembiol.2023.12.002

Adolph, C., Hards, K., Williams, Z. C., Cheung, C.-Y., Keighley, L. M., Jowsey, W. J., Kyte, M., Inaoka, D. K., Kita, K., Mackenzie, J. S., Steyn, A. J. C., Li, Z., Yan, M., Tian, G.-B., Zhang, T., Ding, X., Furkert, D. P., Brimble, M. A., Hickey, A. J. R., … Cook, G. M. (2024). Identification of Chemical Scaffolds That Inhibit the Mycobacterium tuberculosis Respiratory Complex Succinate Dehydrogenase. ACS Infectious Diseases, acsinfecdis.3c00655. https://doi.org/10.1021/acsinfecdis.3c00655

Ahmed, M., Tezera, L. B., Herbert, N., Chambers, M., Reichmann, M. T., Nargan, K., Kloverpris, H., Karim, F., Hlatshwayo, M., Madensein, R., Habesh, M., Hoque, M., Steyn, A. J. C., Elkington, P. T., & Leslie, A. J. (2024). Myeloid cell expression of CD200R is modulated in active TB disease and regulates Mycobacterium tuberculosis infection in a biomimetic model. Frontiers in Immunology, 15, 1360412. https://doi.org/10.3389/fimmu.2024.1360412

Auld, S. C., Barczak, A. K., Bishai, W., Coussens, A. K., Dewi, I. M. W., Mitini-Nkhoma, S. C., Muefong, C., Naidoo, T., Pooran, A., Stek, C., Steyn, A. J. C., Tezera, L., & Walker, N. F. (2024). Pathogenesis of Post-Tuberculosis Lung Disease: Defining Knowledge Gaps and Research Priorities at the 2nd International Post-Tuberculosis Symposium. American Journal of Respiratory and Critical Care Medicine, rccm.202402-0374SO. https://doi.org/10.1164/rccm.202402-0374SO

Bansi-Matharu, L., Revill, P., Taramusi, I., Steen, R., Chabata, S. T., Busza, J., Mangenah, C., Musemburi, S., Machingura, F., Desmond, N., Matambanadzo, P., Shahmanesh, M., Yekeye, R., Mugurungi, O., Cowan, F. M., Hargreaves, J. R., & Phillips, A. N. (2024). The effect on HIV transmission and cost-effectiveness of programmes for female sex workers in East, Central, and Southern Africa: A modelling study. The Lancet Global Health, 12(9), e1436–e1445. https://doi.org/10.1016/S2214-109X(24)00224-9

Banu, B., Khan, Md. M. H., Ali, L., Barnighausen, T., Sauerborn, R., & Souares, A. (2024). Pattern and predictors of non‐adherence to diabetes self‐management recommendations among patients in peripheral district of Bangladesh. Tropical Medicine & International Health, 29(3), 233–https://doi.org/10.1111/tmi.13966

Beattie, T. S., Adhiambo, W., Kabuti, R., Beksinska, A., Ngurukiri, P., Babu, H., Kung’u, M., Nyamweya, C., Mahero, A., Maisha Fiti Study -Champions, Irungu, E., Muthoga, P., Seeley, J., Kimani, J., Weiss, H. A., & Kaul, R. (2024). The epidemiology of HIV infection among female sex workers in Nairobi, Kenya: A structural determinants and life-course perspective. PLOS Global Public Health, 4(1), e0001529. https://doi.org/10.1371/journal.pgph.0001529

Berner-Rodoreda, A., Cobelens, F., Vandamme, A.-M., Froeschl, G., Skordis, J., Renganathan, E., t’Hoen, E., Raviglione, M., Jahn, A., & Bärnighausen, T. (2024). Transferable data exclusivity vouchers are not the solution to the antimicrobial drug development crisis: A commentary on the proposed EU pharma regulation. BMJ Global Health, 9(2), e014605. https://doi.org/10.1136/bmjgh-2023-014605

Brear, M. R., Manderson, L., Nkovana, T., & Harling, G. (2024). Conceptualisations of “good care” within informal caregiving networks for older people in rural South Africa. Social Science & Medicine, 344, 116597. https://doi.org/10.1016/j.socscimed.2024.116597

Brear, M. R., Manderson, L., Nkovana, T., & Harling, G. (2024). Conceptualisations of “good care” within informal caregiving networks for older people in rural South Africa. Social Science & Medicine, 344, 116597. https://doi.org/10.1016/j.socscimed.2024.116597

Buchholtz, N. V. E. J., Nühn, M. M., De Jong, T. C. M., Stienstra, T. A. T., Reddy, K., Ndung’u, T., Ndhlovu, Z. M., Fisher, K., Palmer, S., Wensing, A. M. J., Symons, J., & Nijhuis, M. (2024). Development of a highly sensitive and specific intact proviral DNA assay for HIV-1 subtype B and C. Virology Journal, 21(1), 36. https://doi.org/10.1186/s12985-024-02300-6

Bunker, A., Compoaré, G., Sewe, M. O., Laurent, J. G. C., Zabré, P., Boudo, V., Ouédraogo, W. A., Ouermi, L., Jackson, S. T., Arisco, N., Vijayakumar, G., Yildirim, F. B., Barteit, S., Maggioni, M. A., Woodward, A., Buonocore, J. J., Regassa, M. D., Brück, T., Sié, A., & Bärnighausen, T. (2024). The effects of cool roofs on health, environmental, and economic outcomes in rural Africa: Study protocol for a community-based cluster randomized controlled trial. Trials, 25(1), 59. https://doi.org/10.1186/s13063-023-07804-0

Calderwood, C. J., Marambire, E., Nzvere, F. P., Larsson, L. S., Chingono, R. M. S., Kavenga, F., Redzo, N., Bandason, T., Rusakaniko, S., Mujuru, H. A., Simms, V., Khan, P., Gregson, C. L., Ndhlovu, C. E., Ferrand, R. A., Fielding, K., & Kranzer, K. (2024). Prevalence of chronic conditions and multimorbidity among healthcare workers in Zimbabwe: Results from a screening intervention. PLOS Global Public Health, 4(1), e0002630. https://doi.org/10.1371/journal.pgph.0002630

Chimukuche, R. S., Kawuma, R., Nkosi, B., & Seeley, J. (2024). Scoping review on lessons learnt on the promotion and use of drugs and traditional medicine in Africa during COVID-19. Global Public Health, 19(1), 2323028. https://doi.org/10.1080/17441692.2024.2323028

Chimukuche, R. S., Ndlazi, J., Mtolo, L. T., Bird, K., & Seeley, J. (2024). Evaluation of Drug and Herbal Medicinal Promotions on Social Media During the COVID-19 Pandemic in Relation to World Health Organization Ethical Criteria and South African Health Products Regulatory Authority Guidelines in South Africa: Cross-Sectional Content Analysis. Online Journal of Public Health Informatics, 16, e58378. https://doi.org/10.2196/58378

Cowan, F. M., Machingura, F., Ali, M. S., Chabata, S. T., Takaruza, A., Dirawo, J., Makamba, M., Hove, T., Bansi-Matharu, L., Matambanadzo, P., Shahmanesh, M., Busza, J., Steen, R., Yekeye, R., Mpofu, A., Mugurungi, O., Phillips, A. N., & Hargreaves, J. R. (2024). A risk-differentiated, community-led intervention to strengthen uptake and engagement with HIV prevention and care cascades among female sex workers in Zimbabwe (AMETHIST): A cluster randomised trial. The Lancet Global Health, 12(9), e1424–e1435. https://doi.org/10.1016/S2214-109X(24)00235-3

Cuadros, D. F., Devi, C., Singh, U., Olivier, S., Castle, A. C., Moosa, Y., Edwards, J. A., Kim, H.-Y., Siedner, M. J., Wong, E. B., & Tanser, F. (2024). Convergence of HIV and non-communicable disease epidemics: Geospatial mapping of the unmet health needs in an HIV hyperendemic community in South Africa. BMJ Global Health, 9(1), e012730. https://doi.org/10.1136/bmjgh-2023-012730

Delphin, M., Mohammed, K. S., Downs, L. O., Lumley, S. F., Waddilove, E., Okanda, D., Aliyan, N., Van Schalkwyk, M., Anderson, M., Ocama, P., Maponga, T., Torimiro, J., Iwuji, C., Ndung’u, T., Matthews, P. C., & Taljaard, J. (2024). Under-representation of the WHO African region in clinical trials of interventions against hepatitis B virus infection. The Lancet Gastroenterology & Hepatology, S2468125323003151. https://doi.org/10.1016/S2468-1253(23)00315-1

Fernández Requena, B., Nadeem, S., Reddy, V. P., Naidoo, V., Glasgow, J. N., Steyn, A. J. C., Barbas, C., & Gonzalez-Riano, C. (2024). LiLA: Lipid lung-based ATLAS built through a comprehensive workflow designed for an accurate lipid annotation. Communications Biology, 7(1), 45. https://doi.org/10.1038/s42003-023-05680-7

Fwambah, L., Andisi, C., Streatfield, C., Bromell, R., Hare, J., Esbjörnsson, J., Ndung’u, T., Sanders, E. J., Hassan, A. S., & Nduati, E. (2024). Exposure to common infections may shape basal immunity and potentially HIV-1 acquisition amongst a high-risk population in Coastal Kenya. Frontiers in Immunology, 14, 1283559. https://doi.org/10.3389/fimmu.2023.1283559

Galaviz, K. I., Patel, S. A., Siedner, M. J., Goss, C. W., Gumede, S. B., Johnson, L. C., Ordóñez, C. E., Laxy, M., Klipstein-Grobusch, K., Heine, M., Masterson, M., Mody, A., Venter, W. D. F., Marconi, V. C., Ali, M. K., & Lalla-Edward, S. T. (2024). Integrating hypertension detection and management in HIV care in South Africa: Protocol for a stepped-wedged cluster randomized effectiveness-implementation hybrid trial. Implementation Science Communications, 5(1), 115. https://doi.org/10.1186/s43058-024-00640-6

Gärtner, K., Domínguez-Rodríguez, S., Heaney, J., Gkouleli, T., Grant, P., Dorgham, K., Sauce, D., Soulie, C., Busby, E. J., O’Sullivan, D. M., Spyer, M., Botha, J. C., Muñoz-Fernandez, M. A., Tagarro, A., Cotugno, N., Huggett, J. F., Klein, N., Palma, P., Rojo Conejo, P., … Nastouli, E. (2024). Low unspliced cell-associated HIV RNA in early treated adolescents living with HIV on long suppressive ART. Frontiers in Immunology, 15, 1334236. https://doi.org/10.3389/fimmu.2024.1334236

Ghalichi, L., Goodman-Palmer, D., Whitaker, J., Abio, A., Wilson, M. L., Wallis, L., Norov, B., Aryal, K. K., Malta, D. C., Bärnighausen, T., Geldsetzer, P., Flood, D., Vollmer, S., Theilmann, M., & Davies, J. (2024). Individual characteristics associated with road traffic collisions and healthcare seeking in low- and middle-income countries and territories. PLOS Global Public Health, 4(1), e0002768. https://doi.org/10.1371/journal.pgph.0002768

Gibbs, A., Chirwa, E., Harling, G., Chimbindi, N., Dreyer, J., Herbst, C., Okesola, N., Behuhuma, O., Mthiyane, N., Baisley, K., Zuma, T., Smit, T., McGrath, N., Sherr, L., Seeley, J., & Shahmanesh, M. (2024). Young men’s experiences of violence and poverty and the relationship to sexually transmissible HIV: A cross sectional study from rural South Africa. https://doi.org/10.1101/2024.09.08.24313251

Houle, B., Kabudula, C., Mojola, S. A., Angotti, N., Gómez-Olivé, F. X., Gareta, D., Herbst, K., Clark, S. J., Menken, J., & Canudas-Romo, V. (2024). Mortality variability and differentials by age and causes of death in rural South Africa, 1994–2018. BMJ Global Health, 9(4), e013539. https://doi.org/10.1136/bmjgh-2023-013539

Iwuji, C. C., McMichael, C., Sibanda, E., Orievulu, K. S., Austin, K., & Ebi, K. L. (2024). Extreme weather events and disruptions to HIV services: A systematic review. The Lancet HIV, S2352301824001863. https://doi.org/10.1016/S2352-3018(24)00186-3

Jaumdally, S., Tomasicchio, M., Pooran, A., Esmail, A., Kotze, A., Meier, S., Wilson, L., Oelofse, S., Van Der Merwe, C., Roomaney, A., Davids, M., Suliman, T., Joseph, R., Perumal, T., Scott, A., Shaw, M., Preiser, W., Williamson, C., Goga, A., … Dheda, K. (2024). Frequency, kinetics and determinants of viable SARS-CoV-2 in bioaerosols from ambulatory COVID-19 patients infected with the Beta, Delta or Omicron variants. Nature Communications, 15(1), 2003. https://doi.org/10.1038/s41467-024-45400-1

Jaumdally, S., Tomasicchio, M., Pooran, A., Esmail, A., Kotze, A., Meier, S., Wilson, L., Oelofse, S., Van Der Merwe, C., Roomaney, A., Davids, M., Suliman, T., Joseph, R., Perumal, T., Scott, A., Shaw, M., Preiser, W., Williamson, C., Goga, A., … Dheda, K. (2024). Frequency, kinetics and determinants of viable SARS-CoV-2 in bioaerosols from ambulatory COVID-19 patients infected with the Beta, Delta or Omicron variants. Nature Communications, 15(1), 2003. https://doi.org/10.1038/s41467-024-45400-1

Jockers, D., Ngafuan, R., Baernighausen, T., Kessley, A., White, E. E., Kenny, A., Kraemer, J., Geedeh, J., Rozelle, J., Holmes, L., Obaje, H., Wheh, S., Pedersen, J., Siedner, M. J., Mendin, S., Subah, M., & Hirschhorn, L. R. (2024). Under-five mortality before and after implementation of the Liberia National Community Health Assistant (NCHA) program: A study protocol. PLOS ONE, 19(3), e0272172. https://doi.org/10.1371/journal.pone.0272172

Johnson, L. C. M., Khan, S. H., Ali, M. K., Galaviz, K. I., Waseem, F., Ordóñez, C. E., Siedner, M. J., Nyatela, A., Marconi, V. C., & Lalla-Edward, S. T. (2024). Understanding Barriers and Facilitators to Integrated HIV and Hypertension Care in South Africa [Preprint]. In Review. https://doi.org/10.21203/rs.3.rs-3885096/v1

Kean, I. R. L., Clark, J. A., Zhang, Z., Daubney, E., White, D., Ferrando-Vivas, P., Milla, G., Cuthbertson, B., Pappachan, J., Klein, N., Mouncey, P., Rowan, K., Myburgh, J., Gouliouris, T., Baker, S., Parkhill, J., Pathan, N., & Arctic Research Team. (2024). Short-duration selective decontamination of the digestive tract infection control does not contribute to increased antimicrobial resistance burden in a pilot cluster randomised trial (the ARCTIC Study). Gut, gutjnl-2023-330851. https://doi.org/10.1136/gutjnl-2023-330851

Khaba, T., Papadopoulos, A. O., Nkosi, T., Nxele, S., Ngubane, T., Jajbhay, I., Pansegrouw, J., & Ndhlovu, Z. M. (2024). Safety and practicality of an excisional lymph node study driving HIV cure research in South Africa. Frontiers in Immunology, 15, 1442556. https://doi.org/10.3389/fimmu.2024.1442556

Kippen, A., Nzimande, L., Gareta, D., & Iwuji, C. (2024). The viral load monitoring cascade in HIV treatment programmes in sub-Saharan Africa: A systematic review. BMC Public Health, 24(1), 2603. https://doi.org/10.1186/s12889-024-20013-x

Krause, R., Ogongo, P., Tezera, L., Ahmed, M., Mbano, I., Chambers, M., Ngoepe, A., Magnoumba, M., Muema, D., Karim, F., Khan, K., Lumamba, K., Nargan, K., Madansein, R., Steyn, A., Shalek, A. K., Elkington, P., & Leslie, A. (2024). B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and functional roles. Communications Biology, 7(1), 584. https://doi.org/10.1038/s42003-024-06282-7

Lee, K. S., Wolke, D., Bärnighausen, T., Ouermi, L., Bountogo, M., & Harling, G. (2024). Sexual victimisation, peer victimisation, and mental health outcomes among adolescents in Burkina Faso: A prospective cohort study. The Lancet Psychiatry, 11(2), 134–142. https://doi.org/10.1016/S2215-0366(23)00399-1

Li, Y., Choudhary, M. C., Regan, J., Boucau, J., Nathan, A., Speidel, T., Liew, M. Y., Edelstein, G. E., Kawano, Y., Uddin, R., Deo, R., Marino, C., Getz, M. A., Reynolds, Z., Barry, M., Gilbert, R. F., Tien, D., Sagar, S., Vyas, T. D., … Li, J.(2024) ZSARS-CoV-2 viral clearance and evolution varies by type and severity of immunodeficiency. Science Translational Medicine, 16(731), eadk1599. https://doi.org/10.1126/scitranslmed.adk1599

Lustig, G., Ganga, Y., Rodel, H. E., Tegally, H., Khairallah, A., Jackson, L., Cele, S., Khan, K., Jule, Z., Reedoy, K., Karim, F., Bernstein, M., Ndung’u, T., Moosa, M.-Y. S., Archary, D., De Oliveira, T., Lessells, R., Neher, R. A., Abdool Karim, S. S., & Sigal, A. (2024). SARS-CoV-2 infection in immunosuppression evolves sub-lineages which independently accumulate neutralization escape mutations. Virus Evolution, 10(1), vead075. https://doi.org/10.1093/ve/vead075

Mahlalela, N. B., Manne-Goehler, J., Ohene-Kwofie, D., B. Adams, L., Montana, L., Kahn, K., Rohr, J. K., Bärnighausen, T., & Gómez-Olivé, F. X. (2024). The Association Between HIV-Related Stigma and the Uptake of HIV Testing and ART Among Older Adults in Rural South Africa: Findings from the HAALSI Cohort Study. AIDS and Behavior. https://doi.org/10.1007/s10461-023-04222-w

Manne-Goehler, J., & Siedner, M. J. (2024). Untangling the causal ties between antiretrovirals and obesity. The Lancet HIV, S2352301824002145. https://doi.org/10.1016/S2352-3018(24)00214-5

Mpofana, N., Yalo, M., Gqaleni, N., Dlova, N. C., & Hussein, A. A. (2023). Analysis of Three Species of Cassipourea Traditionally Used for Hypermelanosis in Selected Provinces in South Africa. International Journal of Molecular Sciences, 25(1), 237. https://doi.org/10.3390/ijms25010237

Mussa, A., Jarolimova, J., Ryan, R., Wynn, A., Ashour, D., Bassett, I. V., Philpotts, L. L., Freyne, B., Morroni, C., & Dugdale, C. M. (2024). Syphilis prevalence among people living with and without HIV in sub-Saharan Africa: A systematic review and meta-analysis. Sexually Transmitted Diseases. https://doi.org/10.1097/OLQ.0000000000001920

Myers, B., Regenauer, K. S., Rose, A., Johnson, K., Ndamase, S., Ciya, N., Brown, I., Joska, J., Bassett, I. V., Belus, J. M., Ma, T., Sibeko, G., & Magidson, J. F. (2024). Community health worker training to reduce mental health and substance use stigma towards patients who have disengaged from HIV/TB care in South Africa: Protocol for a stepped wedge hybrid type II pilot implementation trial. Implementation Science Communications, 5(1), 1. https://doi.org/10.1186/s43058-023-00537-w

Nanyonjo, G., Kwena, Z., Nakamanya, S., Okello, E., Oketch, B., Bahemuka, U. M., Ssetaala, A., Okech, B., Price, M. A., Kapiga, S., Fast, P., Bukusi, E., Seeley, J., & the LVCHR study team. (2024). Finding women in fishing communities around Lake Victoria: “Feasibility and acceptability of using phones and tracking devices”. PLOS ONE, 19(1), e0290634. https://doi.org/10.1371/journal.pone.0290634

Ndhlovu, Z., Banjoko, A. W., Ng’uni, T., Naidoo, N., Ramsuran, V., & Hyrien, O. (2024). High Resolution Class I HLA -A, -B, and -C Diversity in Eastern and Southern African Populations. https://doi.org/10.1101/2024.09.04.611164

Ng’uni, T. L., Musale, V., Nkosi, T., Mandolo, J., Mvula, M., Michelo, C., Karim, F., Moosa, M. Y. S., Khan, K., Jambo, K. C., Hanekom, W., Sigal, A., Kilembe, W., & Ndhlovu, Z. M. (2024). Low pre-existing endemic human coronavirus (HCoV-NL63)-specific T cell frequencies are associated with impaired SARS-CoV-2-specific T cell responses in people living with HIV. Frontiers in Immunology, 14, 1291048. https://doi.org/10.3389/fimmu.2023.1291048

Ngwenya, N., Dziva Chikwari, C., Seeley, J., & Ferrand, R. A. (2023). Are concepts of adolescence from the Global North appropriate for Africa? A debate. BMJ Global Health, 8(12), e012614. https://doi.org/10.1136/bmjgh-2023-012614

Ngwenya, N., Smith, T., Shahmanesh, M., Psaros, C., Munikwa, C., Nkosi, K., & Seeley, J. (2024). Social Categorisation and Social Identification: The Mediating Role of Social Isolation and Loneliness in Adolescents Living with HIV. International Journal of Behavioral Medicine, 31(3), 459–467. https://doi.org/10.1007/s12529-023-10205-x

Nimmo, C., Ortiz, A. T., Tan, C. C. S., Pang, J., Acman, M., Millard, J., Padayatchi, N., Grant, A. D., O’Donnell, M., Pym, A., Brynildsrud, O. B., Eldholm, V., Grandjean, L., Didelot, X., Balloux, F., & Van Dorp, L. (2024). Detection of a historic reservoir of bedaquiline/clofazimine resistance-associated variants in Mycobacterium tuberculosis. Genome Medicine, 16(1), 34. https://doi.org/10.1186/s13073-024-01289-5

Olmo-Fontánez, A. M., Scordo, J. M., Schami, A., Garcia-Vilanova, A., Pino, P. A., Hicks, A., Mishra, R., Jose Maselli, D., Peters, J. I., Restrepo, B. I., Nargan, K., Naidoo, T., Clemens, D. L., Steyn, A. J. C., Thacker, V. V., Turner, J., Schlesinger, L. S., & Torrelles, J. B. (2024). Human alveolar lining fluid from the elderly promotes Mycobacterium tuberculosis intracellular growth and translocation into the cytosol of alveolar epithelial cells. Mucosal Immunology, 17(2), 155–168. https://doi.org/10.1016/j.mucimm.2024.01.001

Olmo-Fontánez, A. M., Scordo, J. M., Schami, A., Garcia-Vilanova, A., Pino, P. A., Hicks, A., Mishra, R., Jose Maselli, D., Peters, J. I., Restrepo, B. I., Nargan, K., Naidoo, T., Clemens, D. L., Steyn, A. J. C., Thacker, V. V., Turner, J., Schlesinger, L. S., & Torrelles, J. B. (2024). Human alveolar lining fluid from the elderly promotes Mycobacterium tuberculosis intracellular growth and translocation into the cytosol of alveolar epithelial cells. Mucosal Immunology, S1933021924000011. https://doi.org/10.1016/j.mucimm.2024.01.001

Phelps, N. H., Singleton, R. K., Zhou, B., Heap, R. A., Mishra, A., Bennett, J. E., Paciorek, C. J., Lhoste, V. P., Carrillo-Larco, R. M., Stevens, G. A., Rodriguez-Martinez, A., Bixby, H., Bentham, J., Di Cesare, M., Danaei, G., Rayner, A. W., Barradas-Pires, A., Cowan, M. J., Savin, S., … Ezzati, M. (2024). Worldwide trends in underweight and obesity from 1990 to 2022: A pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults. The Lancet, S0140673623027502. https://doi.org/10.1016/S0140-6736(23)02750-2

Quach, L. T., Ritchie, C. S., Reynolds, Z., Paul, R., Seeley, J., Tong, Y., Hoeppner, S., Okello, S., Nakasujja, N., Olivieri-Mui, B., Saylor, D., Greene, M., Asiimwe, S., Tindimwebwa, E., Atwiine, F., Sentongo, R., Siedner, M. J., & Tsai, A. C. (2024). HIV, Social Networks, and Loneliness among Older Adults in Uganda. AIDS and Behavior. https://doi.org/10.1007/s10461-023-04258-y

Ramsay, M., Crampin, A. C., Bawah, A. A., Gitau, E., & Herbst, K. (2024). The value proposition of coordinated population cohorts across Africa. Annual Review of Biomedical Data Science, 7(1), 277–294. https://doi.org/10.1146/annurev-biodatasci-020722-015026

Rapulana, A. M., Mpotje, T., Baiyegunhi, O. O., Ndlovu, H., Smit, T. K., McHugh, T. D., & Marakalala, M. J. (2024). Combined analysis of host IFN-γ, IL-2 and IP-10 as potential LTBI biomarkers in ESAT-6/CFP-10 stimulated blood. Frontiers in Molecular Medicine, 4, 1345510. https://doi.org/10.3389/fmmed.2024.1345510

Renedo, D., Acosta, J. N., Leasure, A. C., Sharma, R., Krumholz, H. M., De Havenon, A., Alahdab, F., Aravkin, A. Y., Aryan, Z., Bärnighausen, T. W., Basu, S., Burkart, K., Coberly, K., Criqui, M. H., Dai, X., Desai, R., Dharmaratne, S. D., Doshi, R., Elgendy, I. Y., … Sheth, K. N. (2024). Burden of Ischemic and Hemorrhagic Stroke Across the US From 1990 to 2019. JAMA Neurology. https://doi.org/10.1001/jamaneurol.2024.0190

Riou, C., Bhiman, J. N., Ganga, Y., Sawry, S., Ayres, F., Baguma, R., Balla, S. R., Benede, N., Bernstein, M., Besethi, A. S., Cele, S., Crowther, C., Dhar, M., Geyer, S., Gill, K., Grifoni, A., Hermanus, T., Kaldine, H., Keeton, R. S., … Fairlie, L. (2024). Safety and immunogenicity of booster vaccination and fractional dosing with Ad26.COV2.S or BNT162b2 in Ad26.COV2.S-vaccinated participants. PLOS Global Public Health, 4(4), e0002703. https://doi.org/10.1371/journal.pgph.0002703

Rohr, J. K., Huber-Krum, S., Rugarabamu, A., Pearson, E., Francis, J. M., Guo, M., Siril, H., Shah, I., Canning, D., Ulenga, N., & Bärnighausen, T. W. (2024). Impact of a post-partum family planning intervention on contraception and fertility in Tanzania: Two-year follow-up of a cluster-randomised controlled trial. The European Journal of Contraception & Reproductive Health Care, 29(1), 24–31. https://doi.org/10.1080/13625187.2023.2290985

Sahu, M., Schaafsma, T., Szpiro, A. A., Van Rooyen, H., Asiimwe, S., Shahmanesh, M., Krows, M. L., Sithole, N., Van Heerden, A., & Barnabas, R. V. (2024). Performance of patient-collected dried blood spot specimens for HIV-1 viral load testing: Evidence from the DO ART Study in South Africa. AIDS. https://doi.org/10.1097/QAD.0000000000004011

Samuels, V., Mulelu, A. E., Ndlovu, H., & Marakalala, M. J. (2024). Mycobacterial FtsEX-RipC interaction is required for normal growth and cell morphology in rifampicin and low ionic strength conditions. Microbiology Spectrum, 12(3), e02515-23. https://doi.org/10.1128/spectrum.02515-23

Samuels, V., Mulelu, A. E., Ndlovu, H., & Marakalala, M. J. (2024). Mycobacterial FtsEX-RipC interaction is required for normal growth and cell morphology in rifampicin and low ionic strength conditions. Microbiology Spectrum, e02515-23. https://doi.org/10.1128/spectrum.02515-23

Samuels, V., Mulelu, A. E., Ndlovu, H., & Marakalala, M. J. (2024). Mycobacterial FtsEX-RipC interaction is required for normal growth and cell morphology in rifampicin and low ionic strength conditions. Microbiology Spectrum, 12(3), e02515-23. https://doi.org/10.1128/spectrum.02515-23

Samuels, V., Mulelu, A. E., Ndlovu, H., & Marakalala, M. J. (2024). Mycobacterial FtsEX-RipC interaction is required for normal growth and cell morphology in rifampicin and low ionic strength conditions. Microbiology Spectrum, e02515-23. https://doi.org/10.1128/spectrum.02515-23

Ssali, A., Nabaggala, G., Mubiru, M. C., Semakula, I., Seeley, J., & King, R. (2023). Contextual, structural, and mental health experiences of children of women engaged in high-risk sexual behaviour in Kampala: A mixed method study. Frontiers in Public Health, 11, 1185339. https://doi.org/10.3389/fpubh.2023.1185339

Stein, D. T., Reitsma, M. B., Geldsetzer, P., Agoudavi, K., Aryal, K. K., Bahendeka, S., Brant, L. C. C., Farzadfar, F., Gurung, M. S., Guwatudde, D., Houehanou, Y. C. N., Malta, D. C., Martins, J. S., Saeedi Moghaddam, S., Mwangi, K. J., Norov, B., Sturua, L., Zhumadilov, Z., Bärnighausen, T., … Verguet, S. (2024). Hypertension care cascades and reducing inequities in cardiovascular disease in low- and middle-income countries. Nature Medicine. https://doi.org/10.1038/s41591-023-02769-8

The CRyPTIC Consortium, Barilar, I., Battaglia, S., Borroni, E., Brandao, A. P., Brankin, A., Cabibbe, A. M., Carter, J., Chetty, D., Cirillo, D. M., Claxton, P., Clifton, D. A., Cohen, T., Coronel, J., Crook, D. W., Dreyer, V., Earle, S. G., Escuyer, V., Ferrazoli, L., … Zhu, B. (2024). Quantitative measurement of antibiotic resistance in Mycobacterium tuberculosis reveals genetic determinants of resistance and susceptibility in a target gene approach. Nature Communications, 15(1), 488. https://doi.org/10.1038/s41467-023-44325-5

Tomasicchio, M., Jaumdally, S., Wilson, L., Kotze, A., Semple, L., Meier, S., Pooran, A., Esmail, A., Pillay, K., Roberts, R., Kriel, R., Meldau, R., Oelofse, S., Mandviwala, C., Burns, J., Londt, R., Davids, M., Van Der Merwe, C., Roomaney, A., … Dheda, K. (2024). SARS-CoV-2 Viral Replication Persists in the Human Lung for Several Weeks after Symptom Onset. American Journal of Respiratory and Critical Care Medicine, rccm.202308-1438OC. https://doi.org/10.1164/rccm.202308-1438OC

White, R. G., Fiore-Gartland, A. J., Hanekom, W. A., Vekemans, J., Garcia-Basteiro, A. L., Churchyard, G., Rangaka, M. X., Frick, M., Behr, M. A., Hill, P. C., & Mave, V. (2024). What is next for BCG revaccination to prevent tuberculosis? The Lancet Respiratory Medicine, 12(3), e7–e8. https://doi.org/10.1016/S2213-2600(24)00009-2

White, R. G., Fiore-Gartland, A. J., Hanekom, W. A., Vekemans, J., Garcia-Basteiro, A. L., Churchyard, G., Rangaka, M. X., Frick, M., Behr, M. A., Hill, P. C., & Mave, V. (2024). What is next for BCG revaccination to prevent tuberculosis? The Lancet Respiratory Medicine, 12(3), e7–e8. https://doi.org/10.1016/S2213-2600(24)00009-2

Zhu, M., Frank, M. W., Radka, C. D., Jeanfavre, S., Tse, M. W., Pacheco, J. A., Pierce, K., Deik, A., Xu, J., Hussain, S., Hussain, F. A., Xulu, N., Khan, N., Pillay, V., Dong, K. L., Ndung’u, T., Clish, C. B., Rock, C. O., Blainey, P. C., … Kwon, D. S. (2023). Vaginal Lactobacillus fatty acid response mechanisms reveal a novel strategy for bacterial vaginosis treatment [Preprint]. Microbiology. https://doi.org/10.1101/2023.12.30.573720

2023 Publications

Abdullahi, A., Kida, I. M., Maina, U. A., Ibrahim, A. H., Mshelia, J., Wisso, H., Adamu, A., Onyemata, J. E., Edun, M., Yusuph, H., Aliyu, S. H., Charurat, M., Abimiku, A., Abeler-Dorner, L., Fraser, C., Bonsall, D., PANGEA consortium, Abeler-Dörner, L., Ayles, H., … Gupta, R. K. (2023). Limited emergence of resistance to integrase strand transfer inhibitors (INSTIs) in ART-experienced participants failing dolutegravir-based antiretroviral therapy: A cross-sectional analysis of a Northeast Nigerian cohort. Journal of Antimicrobial Chemotherapy, dkad195. https://doi.org/10.1093/jac/dkad195

Adriano Vieira, V., Lim, N., Singh, A., Leitman, E., D’Souza, R. R., Adland, E., Muenchhoff, M., Roider, J., Marín Lopez, M. Á., Carabelli, J., Giandhari, J., Groll, A., Jooste, P., Prado, J. G., Thobakgale, C., Dong, K., Kiepiela, P., Prendergast, A. J., Tudor-Williams, G., Thumbi Ndung'u., Alasdair Leslie, Henrik N Kløverpris., … Goulder, P. (2023). Paediatric HIV slow-progression is associated with early CD8+ T-cell PD-1 expression and a stem-like phenotype. JCI Insight. https://doi.org/10.1172/jci.insight.156049

Allué-Guardia, A., Torrelles, J. B., & Sigal, A. (2023). Tuberculosis and COVID-19 in the elderly: Factors driving a higher burden of disease. Frontiers in Immunology, 14, 1250198. https://doi.org/10.3389/fimmu.2023.1250198

Busang, J., Zuma, T., Herbst, C., Okesola, N., Chimbindi, N., Dreyer, J., Mtshali, N., Smit, T., Ngubane, S., Hlongwane, S., Gumede, D., Jalazi, A., Mdluli, S., Bird, K., Msane, S., Danisa, P., Hanekom, W., Lebina, L., Behuhuma, N., … Shahmanesh, M. (2023). Thetha Nami ngithethe nawe (Let’s Talk): A stepped-wedge cluster randomised trial of social mobilisation by peer navigators into community-based sexual health and HIV care, including pre-exposure prophylaxis (PrEP), to reduce sexually transmissible HIV amongst young people in rural KwaZulu-Natal, South Africa. BMC Public Health, 23(1), 1553. https://doi.org/10.1186/s12889-023-16262-x

Busisiwe, N., Seeley, J., Strode, A., & Parker, M. (2023). Beyond translations, perspectives for researchers to consider to enhance comprehension during consent processes for health research in sub-saharan Africa: A scoping review. BMC Medical Ethics, 24(1), 43. https://doi.org/10.1186/s12910-023-00920-1

Castle, A. C., Hoeppner, S. S., Magodoro, I. M., Singh, U., Moosa, Y., Bassett, I. V., Wong, E. B., Siedner, M. J., & on behalf of the Vukuzazi Study Team. (2023). Association between prior tuberculosis disease and dysglycemia within an HIV-endemic, rural South African population. PLOS ONE, 18(3), e0282371. https://doi.org/10.1371/journal.pone.0282371

Castle, A. C., Hoeppner, S. S., Manne-Goehler, J. M., Olivier, S., Magodoro, I. M., Singh, U., Edwards, J. A., Tanser, F., Bassett, I. V., Wong, E. B., Siedner, M. J., & on behalf of the Vukuzazi Study Team. (2023). Identifying sex-specific anthropometric measures and thresholds for dysglycemia screening in an HIV-endemic rural South African population. PLOS Global Public Health, 3(10), e0001698. https://doi.org/10.1371/journal.pgph.0001698

Chidumwa, G., Olivier, S., Ngubane, H., Zulu, T., Sewpaul, R., Kruse, G., Rigotti, N. A., Siedner, M. J., Reddy, K. P., & Wong, E. B. (2023). Tobacco smoking and prevalence of communicable and non-communicable diseases in rural South Africa: A cross-sectional study [Preprint]. In Review. https://doi.org/10.21203/rs.3.rs-2730894/v1

Cuadros, D. F., Devi, C., Singh, U., Olivier, S., Castle, A., Moosa, Y., Edwards, J. A., Kim, H.-Y., Siedner, M. J., Wong, E. B., & Tanser, F. (2023). Convergence of HIV and non-communicable disease epidemics: Geospatial mapping of the unmet health needs in a HIV Hyperendemic South African community [Preprint]. Epidemiology. https://doi.org/10.1101/2023.03.27.23287807

Cuadros, D. F., Moreno, C. M., Tomita, A., Singh, U., Olivier, S., Castle, A., Moosa, Y., Edwards, J. A., Kim, H.-Y., Siedner, M. J., Wong, E. B., & Tanser, F. (2023). Geospatial assessment of the convergence of communicable and non-communicable diseases in South Africa. Journal of Multimorbidity and Comorbidity, 13, 26335565231204119. https://doi.org/10.1177/26335565231204119

DeSanto, D., Velen, K., Lessells, R., Makgopa, S., Gumede, D., Fielding, K., Grant, A. D., Charalambous, S., & Chetty-Makkan, C. M. (2023). A qualitative exploration into the presence of TB stigmatization across three districts in South Africa. BMC Public Health, 23(1), 504. https://doi.org/10.1186/s12889-023-15407-2

Fehr, J., Gunda, R., Siedner, M. J., Hanekom, W., Ndung´u, T., Grant, A., Lippert, C., & Wong, E. B. (2023). CAD4TB software updates: Different triaging thresholds require caution by users and regulation by authorities. The International Journal of Tuberculosis and Lung Disease, 27(2), 157–160. https://doi.org/10.5588/ijtld.22.0437

Gibbs, A., Gumede, D., Adeagbo, O., Sikweyiya, Y., Chirwa, E., Mkhwanazi, S., Luthuli, M., Xulu, Z., Herbst, C., Zuma, T., Hlongwane, S., Okesola, N., Dreyer, J., Khaula, S., Washington, L., & Shahmanesh, M. (2023). Adaptation and pre-test of a shortened Stepping Stones and Creating Futures intervention focused on HIV for young men in rural South Africa. PLOS Global Public Health, 3(2), e0001632. https://doi.org/10.1371/journal.pgph.0001632

Greuel, M., Sy, F., Bärnighausen, T., Adam, M., Vandormael, A., Gates, J., & Harling, G. (2023). Community Health Worker Use of Smart Devices for Health Promotion: Scoping Review. JMIR MHealth and UHealth, 11, e42023. https://doi.org/10.2196/42023

Haribhai, S., Bhatia, K., & Shahmanesh, M. (2023). Global elective breast- and colorectal cancer surgery performance backlogs, attributable mortality and implemented health system responses during the COVID-19 pandemic: A scoping review. PLOS Global Public Health, 3(4), e0001413. https://doi.org/10.1371/journal.pgph.0001413

Houle, B., Kabudula, C., Gareta, D., Herbst, K., & Clark, S. J. (2023). Household structure, composition and child mortality in the unfolding antiretroviral therapy era in rural South Africa: Comparative evidence from population surveillance, 2000–2015. BMJ Open, 13(3), e070388. https://doi.org/10.1136/bmjopen-2022-070388

Hwa, S.-H., Snyman, J., Bernstein, M., Ganga, Y., Cele, S., Muema, D., Tan, C. W., Khan, K., Karim, F., Hanekom, W., Bernstein, L., Kaufmann, S. H. E., Wang, L.-F., Ndung’u, T., Sigal, A., the COMMIT-KZN Team, Steyn, A., Leslie, A., Ramjit, D., … Ndhlovu, Z. (2023). Association Between Human Immunodeficiency Virus Viremia and Compromised Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2 Beta Variant. The Journal of Infectious Diseases, 227(2), 211–220. https://doi.org/10.1093/infdis/jiac343

Hysenaj, L., Little, S., Kulhanek, K., Magnen, M., Bahl, K., Gbenedio, O. M., Prinz, M., Rodriguez, L., Andersen, C., Rao, A. A., Shen, A., Lone, J.-C., Lupin-Jimenez, L. C., Bonser, L. R., Serwas, N. K., Mick, E., Khalid, M. M., Taha, T. Y., Kumar, R., … Roose, J. P. (2023). SARS-CoV-2 infection of airway organoids reveals conserved use of Tetraspanin-8 by Ancestral, Delta, and Omicron variants. Stem Cell Reports, S2213671123000140. https://doi.org/10.1016/j.stemcr.2023.01.011

Jeewanraj, N., Mandizvo, T., Mulaudzi, T., Gumede, N., Ndhlovu, Z., Ndung’u, T., Gounder, K., & Mann, J. (2023). Partial compartmentalisation of HIV-1 subtype C between lymph nodes, peripheral blood mononuclear cells and plasma. Virology, 582, 62–70. https://doi.org/10.1016/j.virol.2023.03.011

Kasprowicz, V. O., Jeffery, C., Mbuvi, D., Bukirwa, V., Ouattara, K., Kirimi, F., Heitz-Tokpa, K., Gorrethy, M., Chopera, D., Nakanjako, D., Bonfoh, B., Elliott, A., Kinyanjui, S., Bates, I., & Ndung’u, T. (2023). How to improve research capacity strengthening efforts: Learning from the monitoring and evaluation of four research consortia in Africa. Health Research Policy and Systems, 21(1), 109. https://doi.org/10.1186/s12961-023-01056-9

Keter, A. K., Lynen, L., Van Heerden, A., Wong, E., Reither, K., Goetghebeur, E., & Jacobs, B. K. M. (2023). Evaluation of tuberculosis diagnostic test accuracy using Bayesian latent class analysis in the presence of conditional dependence between the diagnostic tests used in a community-based tuberculosis screening study. PLOS ONE, 18(3), e0282417. https://doi.org/10.1371/journal.pone.0282417

Krause, R. G. E., Moyo-Gwete, T., Richardson, S. I., Makhado, Z., Manamela, N. P., Hermanus, T., Mkhize, N. N., Keeton, R., Benede, N., Mennen, M., Skelem, S., Karim, F., Khan, K., Riou, C., Ntusi, N. A. B., Goga, A., Gray, G., Hanekom, W., Garrett, N., … Leslie, A. (2023). Infection pre-Ad26.COV2.S-vaccination primes greater class switching and reduced CXCR5 expression by SARS-CoV-2-specific memory B cells. Npj Vaccines, 8(1), 119. https://doi.org/10.1038/s41541-023-00724-9

Le Roux, S. R., Jassat, W., Dickson, L., Mitrani, L., Cox, H., Mlisana, K., Black, J., Loveday, M., Grant, A. D., Moshabela, M., Kielmann, K., & Nicol, M. P. (2022). The role of emergent champions in policy implementation for decentralised drug-resistant tuberculosis care in South Africa. BMJ Global Health, 7(12), e008907. https://doi.org/10.1136/bmjgh-2022-008907

Luthuli, B., Gounder, K., Deymier, M. J., Dong, K. L., Balazs, A. B., Mann, J. K., & Ndung’u, T. (2023). Generation and characterization of infectious molecular clones of transmitted/founder HIV-1 subtype C viruses. Virology, 583, 14–26. https://doi.org/10.1016/j.virol.2023.04.001

Mabweazara, S., Manne-Goehler, J., Hamer, M., Cellini, J., & Siedner, M. (2023). Characteristics and efficacy of physical activity interventions to improve cardiometabolic and psychosocial outcomes in people living with HIV in sub-Saharan Africa: A protocol for a systematic review. Systematic Reviews, 12(1), 24. https://doi.org/10.1186/s13643-023-02186-5

Mabweazara, S., Manne-Goehler, J., Hamer, M., Cellini, J., & Siedner, M. (2023). Characteristics and efficacy of physical activity interventions to improve cardiometabolic and psychosocial outcomes in people living with HIV in sub-Saharan Africa: A protocol for a systematic review. Systematic Reviews, 12(1), 24. https://doi.org/10.1186/s13643-023-02186-5

Madela, S., Harriman, N., Sewpaul, R., Mbewu, A., Williams, D., Sifunda, S., Manyaapelo, T., Nyembezi, A., & Reddy, S. (2023). Individual and area-level socioeconomic correlates of hypertension prevalence, awareness, treatment, and control in uMgungundlovu, KwaZulu-Natal, South Africa. BMC Public Health, 23(1), 417. https://doi.org/10.1186/s12889-023-15247-0

Madlala, P., Mkhize, Z., Naicker, S., Khathi, S. P., Maikoo, S., Gopee, K., Dong, K. L., & Ndung’u, T. (2023). Genetic variation of the HIV-1 subtype C transmitted/founder viruses long terminal repeat elements and the impact on transcription activation potential and clinical disease outcomes. PLOS Pathogens, 19(6), e1011194. https://doi.org/10.1371/journal.ppat.1011194

Makofane, K., Kim, H., Tchetgen Tchetgen, E., Bassett, M. T., Berkman, L., Adeagbo, O., McGrath, N., Seeley, J., Shahmanesh, M., Yapa, H. M., Herbst, K., Tanser, F., & Bärnighausen, T. (2023). Impact of family networks on uptake of health interventions: Evidence from a community‐randomized control trial aimed at increasing HIV testing in South Africa. Journal of the International AIDS Society, 26(8), e26142. https://doi.org/10.1002/jia2.26142

Moyano, A., Ndlovu, B., Mbele, M., Naidoo, K., Khan, N., Mann, J. K., & Ndung’u, T. (2023). Differing natural killer cell, T cell and antibody profiles in antiretroviral-naive HIV-1 viraemic controllers with and without protective HLA alleles. PLOS ONE, 18(6), e0286507. https://doi.org/10.1371/journal.pone.0286507

Moyano, A., Ndlovu, B., Mbele, M., Naidoo, K., Khan, N., Mann, J. K., & Ndung’u, T. (2023). Differing natural killer cell, T cell and antibody profiles in antiretroviral-naive HIV-1 viraemic controllers with and without protective HLA alleles. PLOS ONE, 18(6), e0286507. https://doi.org/10.1371/journal.pone.0286507

Mpotje, T., More, J., Rajkumar-Bhugeloo, K., Moodley, D., & Marakalala, M. J. (2023). Validation of proteins associated with pathological damage in human tuberculosis granulomas: Study protocol. Wellcome Open Research, 8, 139. https://doi.org/10.12688/wellcomeopenres.19226.1

Mthembu, M., Bowman, K. A., Davies, L. R. L., Khuzwayo, S., Mazibuko, L., Bassett, T., Ramjit, D., Mhlane, Z., Karim, F., Alter, G., Ndung’u, T., & Wong, E. B. (2023). Discrepancy between Mtb-specific IFN-γ and IgG responses in HIV-positive people with low CD4 counts. EBioMedicine, 90, 104504. https://doi.org/10.1016/j.ebiom.2023.104504

Mthiyane, N., Rapulana, A. M., Harling, G., Copas, A., & Shahmanesh, M. (2023). Effect of multi-level interventions on mental health outcomes among adolescents in sub-Saharan Africa: A systematic review. BMJ Open, 13(10), e066586. https://doi.org/10.1136/bmjopen-2022-066586

Mukora, R., Thompson, R. R., Hippner, P., Pelusa, R., Mothibi, M., Lessells, R., Grant, A. D., Fielding, K., Velen, K., Charalambous, S., Dowdy, D. W., & Sohn, H. (2023). Human resource time commitments and associated costs of Community Caregiver outreach team operations in South Africa. PLOS ONE, 18(3), e0282425. https://doi.org/10.1371/journal.pone.0282425

Musvosvi, M., Huang, H., Wang, C., Xia, Q., Rozot, V., Krishnan, A., Acs, P., Cheruku, A., Obermoser, G., Leslie, A., Behar, S. M., Hanekom, W. A., Bilek, N., Fisher, M., Kaufmann, S. H. E., Walzl, G., Hatherill, M., Davis, M. M., Scriba, T. J., … Van, T. (2023). T cell receptor repertoires associated with control and disease progression following Mycobacterium tuberculosis infection. Nature Medicine. https://doi.org/10.1038/s41591-022-02110-9

Naidoo, K. K., Highton, A. J., Baiyegunhi, O. O., Bhengu, S. P., Dong, K. L., Bunders, M. J., Altfeld, M., & Ndung’u, T. (2023). Early initiation of antiretroviral therapy preserves the metabolic function of CD4+ T-cells in subtype C HIV-1 infection. The Journal of Infectious Diseases, jiad432. https://doi.org/10.1093/infdis/jiad432

Nascimento, F. F., Ragonnet-Cronin, M., Golubchik, T., Danaviah, S., Derache, A., Fraser, C., & Volz, E. (2022). Evaluating whole HIV-1 genome sequence for estimation of incidence and migration in a rural South African community. Wellcome Open Research, 7, 174. https://doi.org/10.12688/wellcomeopenres.17891.1

Ndung’u, T. (2023). Fighting HIV where it matters most. Nature Microbiology, 8(10), 1751–1753. https://doi.org/10.1038/s41564-023-01463-2

Ndung’u, T. (2023). The KT Jeang retrovirology prize 2023: Thumbi Ndung’u. Retrovirology, 20(1), 17, s12977-023-00632–00639. https://doi.org/10.1186/s12977-023-00632-9

Nelson, K. N., Churchyard, G., Cobelens, F., Hanekom, W. A., Hill, P. C., Lopman, B., Mave, V., Rangaka, M. X., Vekemans, J., White, R. G., Wong, E. B., Martinez, L., & García-Basteiro, A. L. (2023). Measuring indirect transmission-reducing effects in tuberculosis vaccine efficacy trials: Why and how? The Lancet Microbe, S266652472300112X. https://doi.org/10.1016/S2666-5247(23)00112-X

Nguyen, A. N., Plotkin, A. L., Odumade, O. A., De Armas, L., Pahwa, S., Morrocchi, E., Cotugno, N., Rossi, P., Foster, C., Domínguez-Rodríguez, S., Tagarro, A., Syphurs, C., Diray-Arce, J., Fatou, B., Ozonoff, A., Levy, O., Palma, P., Smolen, K. K., on the behalf of the EPIICAL Consortium, … Kityo, C. (2023). Effective early antiretroviral therapy in perinatal-HIV infection reduces subsequent plasma inflammatory profile. Pediatric Research. https://doi.org/10.1038/s41390-023-02669-0

Plazy, M., Diallo, A., Hlabisa, T., Okesola, N., Iwuji, C., Herbst, K., Boyer, S., Lert, F., McGrath, N., Pillay, D., Dabis, F., Larmarange, J., Orne-Gliemann, J., & for the ANRS TasP Study Group. (2023). Implementation and effectiveness of a linkage to HIV care intervention in rural South Africa (ANRS 12249 TasP trial). PLOS ONE, 18(1), e0280479. https://doi.org/10.1371/journal.pone.0280479

Randera-Rees, S., Clarence Safari, W., Gareta, D., Herbst, K., Baisley, K., & Grant, A. D. (2023). Can we find the missing men in clinics? Clinic attendance by sex and HIV status in rural South Africa. Wellcome Open Research, 6, 169. https://doi.org/10.12688/wellcomeopenres.16702.2

Roest, J., Nkosi, B., Seeley, J., Molyneux, S., & Kelley, M. (2023). Respecting relational agency in the context of vulnerability: What can research ethics learn from the social sciences? Bioethics, bioe.13139. https://doi.org/10.1111/bioe.13139

Shinde, S., Noor, R. A., Mwanyika‐Sando, M., Moshabela, M., Tadesse, A. W., Sherfi, H., Vandormael, A., Young, T., Tinkasimile, A., Drysdale, R., Baernighausen, T., Sharma, D., & Fawzi, W. W. (2023). Adolescent health and well‐being in sub‐Saharan Africa: Strengthening knowledge base and research capacity through a collaborative multi‐country school‐based study. Maternal & Child Nutrition, e13411. https://doi.org/10.1111/mcn.13411

Sigal, A. (2023). Boosting in the age of Omicron. ELife, 12, e87358. https://doi.org/10.7554/eLife.87358

Singh, U., Olivier, S., Cuadros, D., Castle, A., Moosa, Y., Edwards, J. A., Kim, H.-Y., Siedner, M. J., Tanser, F., & Wong, E. B. (2023). Quantifying met and unmet health needs for HIV, hypertension and diabetes in rural KwaZulu-Natal, South Africa [Preprint]. In Review. https://doi.org/10.21203/rs.3.rs-2702048/v1

Singh, U., Olivier, S., Cuadros, D., Castle, A., Moosa, Y., Zulu, T., Edwards, J. A., Kim, H.-Y., Gunda, R., Koole, O., Surujdeen, A., Gareta, D., Munatsi, D., Modise, T. H., Dreyer, J., Nxumalo, S., Smit, T. K., Ordering-Jespersen, G., Mpofana, I. B., … Harilall, S. (2023). The met and unmet health needs for HIV, hypertension, and diabetes in rural KwaZulu-Natal, South Africa: Analysis of a cross-sectional multimorbidity survey. The Lancet Global Health, 11(9), e1372–e1382. https://doi.org/10.1016/S2214-109X(23)00239-5

Sithole, N., Castle, A., Nxumalo, S., Mazibuko, L., Manyaapelo, T., Abrahams-Gessel, S., Dlamini, S., Gareta, D., Orne-Gliemann, J., Baisley, K., Bachmann, M., Magula, N., Gaziano, T. A., & Siedner, M. J. (2023). Protocol: Implementation evaluation of a combination intervention for sustainable blood pressure control in rural KwaZulu-Natal, South Africa (IMPACT BP): A three-arm, unblinded, parallel group individually randomized clinical trial. Contemporary Clinical Trials, 131, 107258. https://doi.org/10.1016/j.cct.2023.107258

Smith, J., Bansi-Matharu, L., Cambiano, V., Dimitrov, D., Bershteyn, A., van de Vijver, D., Kripke, K., Revill, P., Boily, M.-C., Meyer-Rath, G., Taramusi, I., Lundgren, J. D., van Oosterhout, J. J., Kuritzkes, D., Schaefer, R., Siedner, M. J., Schapiro, J., Delany-Moretlwe, S., Landovitz, R. J., … Phillips, A. N. (2023). Predicted effects of the introduction of long-acting injectable cabotegravir pre-exposure prophylaxis in sub-Saharan Africa: A modelling study. The Lancet HIV, S2352301822003654. https://doi.org/10.1016/S2352-3018(22)00365-4

Turkova, A., White, E., Kekitiinwa, A. R., Mumbiro, V., Kaudha, E., Liberty, A., Ahimbisibwe, G. M., Moloantoa, T., Srirompotong, U., Mosia, N. R., Puthanakit, T., Kobbe, R., Fortuny, C., Kataike, H., Bbuye, D., Na-Rajsima, S., Coelho, A., Lugemwa, A., Bwakura-Dangarembizi, M. F., … Zuidewind, P. (2023). Neuropsychiatric manifestations and sleep disturbances with dolutegravir-based antiretroviral therapy versus standard of care in children and adolescents: A secondary analysis of the ODYSSEY trial. The Lancet Child & Adolescent Health, S2352464223001645. https://doi.org/10.1016/S2352-4642(23)00164-5

Vieira, V., Lim, N., Singh, A., Leitman, E., Dsouza, R., Adland, E., Muenchhoff, M., Roider, J., Marin Lopez, M., Carabelli, J., Giandhari, J., Groll, A., Jooste, P., Prado, J. G., Thobakgale, C., Dong, K., Kiepiela, P., Prendergast, A. J., Tudor-Williams, G., … Goulder, P. (2023). Slow progression of pediatric HIV associates with early CD8+ T cell PD-1 expression and a stem-like phenotype. JCI Insight, 8(3), e156049. https://doi.org/10.1172/jci.insight.156049

2022 Publications

Edwards, A., Mahomed-Asmail, F., Olivier, A.-M., van der Linde, J., Khoza-Shangase, K., Moroe, N., & Neille, J. (2022). In pursuit of best practice through contextually relevant, accountable and responsive research. South African Journal of Communication Disorders, 69(1). https://doi.org/10.4102/sajcd.v69i1.945

Adeagbo, O. A., Seeley, J., Gumede, D., Xulu, S., Dlamini, N., Luthuli, M., Dreyer, J., Herbst, C., Cowan, F., Chimbindi, N., Hatzold, K., Okesola, N., Johnson, C., Harling, G., Subedar, H., Sherr, L., McGrath, N., Corbett, L., & Shahmanesh, M. (2022). Process evaluation of peer-to-peer delivery of HIV self-testing and sexual health information to support HIV prevention among youth in rural KwaZulu-Natal, South Africa: Qualitative analysis. BMJ Open, 12(2), e048780. https://doi.org/10.1136/bmjopen-2021-048780

Ahmed, M., Mackenzie, J., Tezera, L., Krause, R., Truebody, B., Garay-Baquero, D., Vallejo, A., Govender, K., Adamson, J., Fisher, H., Essex, J. W., Mansour, S., Elkington, P., Steyn, A. J. C., & Leslie, A. (2022).Mycobacterium tuberculosis senses host Interferon-γ via the membrane protein MmpL10. Communications Biology, 5(1), 1317. https://doi.org/10.1038/s42003-022-04265-0

Ahmed, M., Mackenzie, J., Tezera, L., Krause, R., Truebody, B., Garay-Baquero, D., Vallejo, A., Govender, K., Adamson, J., Fisher, H., Essex, J. W., Mansour, S., Elkington, P., Steyn, A. J. C., & Leslie, A. (2022). Mycobacterium tuberculosis senses host Interferon-γ via the membrane protein MmpL10. Communications Biology, 5(1), 1317. https://doi.org/10.1038/s42003-022-04265-0

Amuge, P., Lugemwa, A., Wynne, B., Mujuru, H. A., Violari, A., Kityo, C. M., Archary, M., Variava, E., White, E., Turner, R. M., Shakeshaft, C., Ali, S., Nathoo, K. J., Atwine, L., Liberty, A., Bbuye, D., Kaudha, E., Mngqibisa, R., Mosala, M., … Zuidewind, P. (2022). Once-daily dolutegravir-based antiretroviral therapy in infants and children living with HIV from age 4 weeks: Results from the below 14 kg cohort in the randomised ODYSSEY trial. The Lancet HIV, 9(9), e638–e648. https://doi.org/10.1016/S2352-3018(22)00163-1

Arsenault, C., Gage, A., Kim, M. K., Kapoor, N. R., Akweongo, P., Amponsah, F., Aryal, A., Asai, D., Awoonor-Williams, J. K., Ayele, W., Bedregal, P., Doubova, S. V., Dulal, M., Gadeka, D. D., Gordon-Strachan, G., Mariam, D. H., Hensman, D., Joseph, J. P., Kaewkamjornchai, P., … Kruk, M. E. (2022). Covid-19 and resilience of healthcare systems in ten countries. Nature Medicine, 28(6), 1314–1324. https://doi.org/10.1038/s41591-022-01750-1

Baisley, K., Orne‐Gliemann, J., Larmarange, J., Plazy, M., Collier, D., Dreyer, J., Mngomezulu, T., Herbst, K., Hanekom, W., Dabis, F., Siedner, M. J., & Iwuji, C. (2022). Early HIV treatment and survival over six years of observation in the ANRS 12249 Treatment as Prevention Trial. HIV Medicine, hiv.13263. https://doi.org/10.1111/hiv.13263

Baiyegunhi, O. O., Mann, J., Khaba, T., Nkosi, T., Mbatha, A., Ogunshola, F., Chasara, C., Ismail, N., Ngubane, T., Jajbhay, I., Pansegrouw, J., Dong, K. L., Walker, B. D., Ndung’u, T., & Ndhlovu, Z. M. (2022). CD8 lymphocytes mitigate HIV-1 persistence in lymph node follicular helper T cells during hyperacute-treated infection. Nature Communications, 13(1), 4041. https://doi.org/10.1038/s41467-022-31692-8

Bengu, N., Mchunu, N., Mokhethi, S., Fillis, R., Cromhout, G., Lobenstein, J. van, Graza, Y., Kapongo, C., Chinniah, K., Bhoola, R., Adland, E., Puertas, M. C., Ndung’u, T., Martinez-Picado, J., Archary, M., & Goulder, P. J. R. (2022). Next-generation point-of-care testing in pediatric human immunodeficiency virus infection facilitates diagnosis and monitoring of treatment. Medicine, 101(27), e29228. https://doi.org/10.1097/MD.0000000000029228

Bernabe, K. J., Siedner, M., Tsai, A. C., Marconi, V. C., & Murphy, R. A. (2022). Detection of HIV virologic failure and switch to second-line therapy: A systematic review and meta-analysis of data from sub-Saharan Africa. Open Forum Infectious Diseases, ofac121. https://doi.org/10.1093/ofid/ofac121

Boeke, C. E., Khan, S., Walsh, F. J., Lejeune, C., Hettema, A., Spiegelman, D., Okello, V., & Bärnighausen, T. (2021). Longitudinal analysis of client appointment adherence under Universal Test and Treat strategy: A stepped‐wedge trial. HIV Medicine, 22(9), 854–859. https://doi.org/10.1111/hiv.13144

Bogart, L. M., Shazi, Z., MacCarthy, S., Mendoza-Graf, A., Wara, N. J., Zionts, D., Dube, N., Govere, S., & Bassett, I. V. (2022). Implementation of South Africa’s Central Chronic Medicine Dispensing and Distribution Program for HIV Treatment: A Qualitative Evaluation. AIDS and Behavior, 26(8), 2600–2612. https://doi.org/10.1007/s10461-022-03602-y

Bousmah, M.-Q., Iwuji, C., Okesola, N., Orne-Gliemann, J., Pillay, D., Dabis, F., Larmarange, J., & Boyer, S. (2022). Costs and economies of scale in repeated home-based HIV counselling and testing: Evidence from the ANRS 12249 treatment as prevention trial in South Africa. Social Science & Medicine, 305, 115068. https://doi.org/10.1016/j.socscimed.2022.115068

Cele, S., Karim, F., Lustig, G., San, J. E., Hermanus, T., Tegally, H., Snyman, J., Moyo-Gwete, T., Wilkinson, E., Bernstein, M., Khan, K., Hwa, S.-H., Tilles, S. W., Singh, L., Giandhari, J., Mthabela, N., Mazibuko, M., Ganga, Y., Gosnell, B. I., Karim SA, Hanekom W, Van Voorhis WC, Ndungâ U T; COMMIT-KZN Team, Lessells RJ, Moore PL, Moosa MS, de Oliveira T, Sigal A. (2022). SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escape. Cell Host & Microbe, S1931312822000415. https://doi.org/10.1016/j.chom.2022.01.005

Chidumwa, G., Chimbindi, N., Herbst, C., Okeselo, N., Dreyer, J., Zuma, T., Smith, T., Molina, J.-M., Khoza, T., McGrath, N., Seeley, J., Pillay, D., Tanser, F., Harling, G., Sherr, L., Copas, A., Baisley, K., & Shahmanesh, M. (2022). Isisekelo Sempilo study protocol for the effectiveness of HIV prevention embedded in sexual health with or without peer navigator support (Thetha Nami) to reduce prevalence of transmissible HIV amongst adolescents and young adults in rural KwaZulu-Natal: A 2 × 2 factorial randomised controlled trial. BMC Public Health, 22(1), 454. https://doi.org/10.1186/s12889-022-12796-8

Chimbindi, N., & Shahmanesh, M. (2022). PrEP dispensing with HIV self-testing. The Lancet HIV, 9(7), e450–e451. https://doi.org/10.1016/S2352-3018(22)00171-0

Chimukuche, R. S., Kawuma, R., Mahapa, N., Mkhwanazi, S., Singh, N., Siva, S., Ruzagira, E., Seeley, J., On behalf of the PrEPVacc Study Group, Gray, G., Singh, N., Gaffoor, Z., Morar, N., Sithole, T., Woeber, K., Siva, S., Hwengwere, E., Chidawanyika, R. S., Mahapa, N., … Robb, M. (2022). Examining oral pre-exposure prophylaxis (PrEP) literacy among participants in an HIV vaccine trial preparedness cohort study. BMC Health Services Research, 22(1), 1336. https://doi.org/10.1186/s12913-022-08730-8

Chimukuche, R. S., Nkosi, B., & Seeley, J. (2022). Policy and Guideline Review of Vaccine Safety for COVID-19 in Pregnant Women in Southern Africa, with a Particular Focus on South Africa. Vaccines, 10(12), 2077. https://doi.org/10.3390/vaccines10122077

Chimukuche, R., Ngwenya, N., Seeley, J., Nxumalo, P., Nxumalo, Z., Godongwana, M., Radebe, N., Myburgh, N., Adedini, S., & Cutland, C. (2022). Assessing Community Acceptance of Maternal Immunisation in Rural KwaZulu-Natal, South Africa: A Qualitative Investigation. Vaccines, 10(3), 415. https://doi.org/10.3390/vaccines10030415

Cowan, F. M., Machingura, F., Chabata, S. T., Ali, M. S., Busza, J., Steen, R., Desmond, N., Shahmanesh, M., Revill, P., Mpofu, A., Yekeye, R., Mugurungi, O., Phillips, A. N., & Hargreaves, J. R. (2022). Differentiated prevention and care to reduce the risk of HIV acquisition and transmission among female sex workers in Zimbabwe: Study protocol for the ‘AMETHIST’ cluster randomised trial. Trials, 23(1), 209. https://doi.org/10.1186/s13063-022-06119-w

Dzomba, A., Kim, H.-Y., Tomita, A., Vandormael, A., Govender, K., & Tanser, F. (2022). Predictors of migration in an HIV hyper-endemic rural South African community: Evidence from a population-based cohort (2005–2017). BMC Public Health, 22(1), 1141. https://doi.org/10.1186/s12889-022-13526-w

Fardoos, R., Nyquist, S. K., Asowata, O. E., Kazer, S. W., Singh, A., Ngoepe, A., Giandhari, J., Mthabela, N., Ramjit, D., Singh, S., Karim, F., Buus, S., Anderson, F., Porterfield, J. Z., Sibiya, A. L., Bipath, R., Moodley, K., Kuhn, W., Berger, B., … Kløverpris, H. N. (2022). HIV specific CD8+ TRM-like cells in tonsils express exhaustive signatures in the absence of natural HIV control. Frontiers in Immunology, 13, 912038. https://doi.org/10.3389/fimmu.2022.912038

Fentress, M., Henwood, P. C., Maharaj, P., Mitha, M., Khan, D., Caligiuri, P., Karat, A. S., Olivier, S., Edwards, A., Ramjit, D., Ngcobo, N., Wong, E. B., & Grant, A. D. (2022). High sensitivity of ultrasound for the diagnosis of tuberculosis in adults in South Africa: A proof-of-concept study. PLOS Global Public Health, 2(10), e0000800. https://journals.plos.org/globalpublichealth/article?id=10.1371/journal.pgph.0000800

Fentress, M., Henwood, P. C., Maharaj, P., Mitha, M., Khan, D., Jackpersad, R., Pitcher, R., Redfern, A., Lopez Varela, E., van der Zalm, M. M., Wong, E. B., Palmer, M., & Grant, A. D. (2022). Thoracic ultrasound for TB diagnosis in adults and children. Public health action, 12(1), 3–6. https://doi.org/10.5588/pha.21.0072

Fernández-Luis, S., Lain, M. G., Serna-Pascual, M., Domínguez-Rodríguez, S., Kuhn, L., Liberty, A., Barnabas, S., Lopez-Varela, E., Otwombe, K., Danaviah, S., Nastouli, E., Palma, P., Cotugno, N., Spyer, M., Giannuzzi, V., Giaquinto, C., Violari, A., Cotton, M. F., Nhampossa, T., Klein, N., Behuhuma, O., Goulder, P … Maiga, A. (2022). Optimizing the World Health Organization algorithm for HIV vertical transmission risk assessment by adding maternal self-reported antiretroviral therapy adherence. BMC Public Health, 22(1), 1312. https://doi.org/10.1186/s12889-022-13543-9

Fisher, K. L., Moodley, D., Rajkumar-Bhugeloo, K., Baiyegunhi, O. O., Karim, F., Ndlovu, H., Ndung’u, T., & Marakalala, M. J. (2022). Elevated IP-10 at the protein and gene level associates with pulmonary TB. Frontiers in Cellular and Infection Microbiology, 12, 908144. https://doi.org/10.3389/fcimb.2022.908144

Floyd, S., Mulwa, S., Magut, F., Gourlay, A., Mthiyane, N., Kamire, V., Osindo, J., Otieno, M., Chimbindi, N., Ziraba, A., Phillips-Howard, P., Kwaro, D., Shahmanesh, M., & Birdthistle, I. (2022). DREAMS impact on HIV status knowledge and sexual risk among cohorts of young women in Kenya and South Africa. AIDS, 36(Supplement 1), S61–S73. https://doi.org/10.1097/QAD.0000000000003157

Gibbs, A., Desmond, C., Barnett, T., Shahmanesh, M., & Seeley, J. (2022). Is hope associated with HIV-acquisition risk and intimate partner violence amongst young women and men? A cross-sectional study in urban informal settlements in South Africa. AIDS Care, 1–8. https://doi.org/10.1080/09540121.2022.2143470

Gibbs, J., Solomon, D., Jackson, L., Mullick, S., Burns, F., & Shahmanesh, M. (2022). Measuring and evaluating sexual health in the era of digital health: Challenges and opportunities. Sexual Health. https://doi.org/10.1071/SH22068

Gideon, H. P., Hughes, T. K., Tzouanas, C. N., Wadsworth, M. H., Tu, A. A., Gierahn, T. M., … Leslie, A., Behar, S.M., Bryson, B., Flynn, J.L., Fortune, S.M., Shalek, A. K. (2022). Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control. Immunity, S1074761322001753. https://doi.org/10.1016/j.immuni.2022.04.004

Gourlay, A. J., Birdthistle, I., Mulwa, S., Mthiyane, N. T., Magut, F., Chimbindi, N., Ziraba, A., Otieno, M., Kwaro, D., Osindo, J., Kamire, V., Shahmanesh, M., & Floyd, S. (2022). Awareness and uptake of the Determined, Resilient, Empowered, AIDS-free, Mentored and Safe HIV prevention package over time among population-based cohorts of young women in Kenya and South Africa. AIDS, 36(Supplement 1), S27–S38. https://doi.org/10.1097/QAD.0000000000003120

Gourlay, A., Floyd, S., Magut, F., Mulwa, S., Mthiyane, N., Wambiya, E., Otieno, M., Kamire, V., Osindo, J., Chimbindi, N., Ziraba, A., Kwaro, D., Shahmanesh, M., & Birdthistle, I. (2022). Impact of the DREAMS Partnership on social support and general self-efficacy among adolescent girls and young women: Causal analysis of population-based cohorts in Kenya and South Africa. BMJ Global Health, 7(3), e006965. https://doi.org/10.1136/bmjgh-2021-006965

Govere-Hwenje, S., Jarolimova, J., Yan, J., Khumalo, A., Zondi, G., Ngcobo, M., Wara, N. J., Zionts, D., Bogart, L. M., Parker, R. A., & Bassett, I. V. (2022). Willingness to accept Covid-19 vaccination among people living with HIV in a high HIV prevalence community. BMC Public Health, 22(1), 1239. https://doi.org/10.1186/s12889-022-13623-w

Greaney, A. J., Eguia, R. T., Starr, T. N., Khan, K., Franko, N., Logue, J. K., Lord, S. M., Speake, C., Chu, H. Y., Sigal, A., & Bloom, J. D. (2022). The SARS-CoV-2 Delta variant induces an antibody response largely focused on class 1 and 2 antibody epitopes. PLOS Pathogens, 18(6), e1010592. https://doi.org/10.1371/journal.ppat.1010592

Greaney, A. J., Starr, T. N., Eguia, R. T., Loes, A. N., Khan, K., Karim, F., Cele, S., Bowen, J. E., Logue, J. K., Corti, D., Veesler, D., Chu, H. Y., Sigal, A., & Bloom, J. D. (2022). A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy. PLOS Pathogens, 18(2), e1010248. https://doi.org/10.1371/journal.ppat.1010248

Gumede, D., Meyer-Weitz, A., Zuma, T., Shahmanesh, M., & Seeley, J. (2022). A qualitative investigation of facilitators and barriers to DREAMS uptake among adolescents with grandparent caregivers in rural KwaZulu-Natal, South Africa. PLOS Global Public Health, 2(9), e0000369. https://doi.org/10.1371/journal.pgph.0000369

Inghels, M., Kim, H.-Y., Mathenjwa, T., Shahmanesh, M., Seeley, J., Wyke, S., McGrath, N., Sartorius, B., Yapa, H. M., Dobra, A., Bärnighausen, T., & Tanser, F. (2022). Can a conditional financial incentive (CFI) reduce socio-demographic inequalities in home-based HIV testing uptake? A secondary analysis of the HITS clinical trial intervention in rural South Africa. Social Science & Medicine, 311, 115305. https://doi.org/10.1016/j.socscimed.2022.115305

Iwuji, C., Pillay, D., Shamu, P., Murire, M., Nzenze, S., Cox, L.-A., & Mullick, S. (2022). A systematic review of antimicrobial resistance in Neisseria gonorrhoeae and Mycoplasma genitalium in sub-Saharan Africa. Journal of Antimicrobial Chemotherapy, dkac159. https://doi.org/10.1093/jac/dkac159

Jahagirdar, D., Walters, M. K., Novotney, A., Brewer, E. D., Frank, T. D., Carter, A., Biehl, M. H., Abbastabar, H., Abhilash, E. S., Abu-Gharbieh, E., Abu-Raddad, L. J., Adekanmbi, V., Adeyinka, D. A., Adnani, Q. E. S., Afzal, S., Aghababaei, S., Ahinkorah, B. O., Ahmad, S., Ahmadi, K., … Kyu, H. H. (2021). Global, regional, and national sex-specific burden and control of the HIV epidemic, 1990–2019, for 204 countries and territories: The Global Burden of Diseases Study 2019. The Lancet HIV, 8(10), e633–e651. https://doi.org/10.1016/S2352-3018(21)00152-1

Jarolimova, J., Platt, L. R., Curtis, M. R., Philpotts, L. L., Bekker, L.-G., Morroni, C., Shahmanesh, M., Mussa, A., Barracks, K., Ciaranello, A. L., Parker, R. A., Bassett, I. V., & Dugdale, C. M. (2022). Curable sexually transmitted infections among women with HIV in sub-Saharan Africa. AIDS, 36(5), 697–709. https://doi.org/10.1097/QAD.0000000000003163

Kampiire, L., Archary, M., Frigati, L., Penazatto, M., & Brusamento, S. (2022). Immunization for Children Living With HIV: A Scoping Review. Journal of the Pediatric Infectious Diseases Society, piab119. https://doi.org/10.1093/jpids/piab119

Keeton, R., Tincho, M. B., Ngomti, A., Baguma, R., Benede, N., Suzuki, A., Khan, K., Cele, S., Bernstein, M., Karim, F., Madzorera, S. V., Moyo-Gwete, T., Mennen, M., Skelem, S., Adriaanse, M., Mutithu, D., Aremu, O., Stek, C., du Bruyn, E., … Riou, C. (2022). T cell responses to SARS-CoV-2 spike cross-recognize Omicron. Nature. https://doi.org/10.1038/s41586-022-04460-3

Kemp, S. A., Charles, O. J., Derache, A., Smidt, W., Martin, D. P., Iwuji, C., Adamson, J., Govender, K., de Oliveira, T., Dabis, F., Pillay, D., Goldstein, R. A., & Gupta, R. K. (2022). HIV-1 Evolutionary Dynamics under Nonsuppressive Antiretroviral Therapy. MBio, e00269-22. https://doi.org/10.1128/mbio.00269-22

Khan, K., Karim, F., Cele, S., Reedoy, K., San, J. E., Lustig, G., Tegally, H., Rosenberg, Y., Bernstein, M., Jule, Z., Ganga, Y., Ngcobo, N., Mazibuko, M., Mthabela, N., Mhlane, Z., Mbatha, N., Miya, Y., Giandhari, J., Ramphal, Y., … Sigal, A. (2022). Omicron infection enhances Delta antibody immunity in vaccinated persons. Nature. https://doi.org/10.1038/s41586-022-04830-x

Khan, K., Lustig, G., Bernstein, M., Archary, D., Cele, S., Karim, F., Smith, M., Ganga, Y., Jule, Z., Reedoy, K., Miya, Y., Mthabela, N., Magula, N. P., Lessells, R., de Oliveira, T., Gosnell, B. I., Abdool Karim, S., Garrett, N., Hanekom, W., … Ndhlovu, Z. (2022). Immunogenicity of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Ad26.CoV2.S Vaccination in People Living With Human Immunodeficiency Virus (HIV). Clinical Infectious Diseases, 75(1), e857–e864. https://doi.org/10.1093/cid/ciab1008

Kim, H.-Y., Cuadros, D., Wilkinson, E., Junqueira, D. M., Oliveira, T. de, & Tanser, F. (2022). The geography and inter-community configuration of new sexual partnership formation in a rural South African population over fourteen years (2003–2016). PLOS Global Public Health, 2(3), e0000055. https://doi.org/10.1371/journal.pgph.0000055

Kruse, G., Zulu, T., Ngubane, H., Reddy, K., Siedner, M., Rigotti, N. A., Seeley, J., Ngwenya, N., & Wong, E. (2022). The ethics of conducting observational tobacco research without providing treatment to people who use tobacco: A case example from South Africa. BMJ Global Health, 7(7), e009732. https://doi.org/10.1136/bmjgh-2022-009732

Lustig, G., Ganga, Y., Rodel, H., Tegally, H., Jackson, L., Cele, S., Khan, K., Jule, Z., Reedoy, K., Karim, F., Bernstein, M., Moosa, M.-Y. S., Archary, D., de Oliveira, T., Lessells, R., Abdool Karim, S. S., & Sigal, A. (2022). SARS-CoV-2 evolves increased infection elicited cell death and fusion in an immunosuppressed individual [Preprint]. Infectious Diseases (except HIV/AIDS). https://doi.org/10.1101/2022.11.23.22282673

Lustig, G., Ganga, Y., Rodel, H., Tegally, H., Jackson, L., Cele, S., Khan, K., Jule, Z., Reedoy, K., Karim, F., Bernstein, M., Moosa, M.-Y. S., Archary, D., de Oliveira, T., Lessells, R., Abdool Karim, S. S., & Sigal, A. (2022). SARS-CoV-2 evolves increased infection elicited cell death and fusion in an immunosuppressed individual [Preprint]. Infectious Diseases (except HIV/AIDS). https://doi.org/10.1101/2022.11.23.22282673

Luthuli, M., Ngwenya, N., Gumede, D., Gunda, R., Gareta, D., Koole, O., Siedner, M. J., Wong, E. B., & Seeley, J. (2022). Participant recall and understandings of information on biobanking and future genomic research: Experiences from a multi-disease community-based health screening and biobank platform in rural South Africa. BMC Medical Ethics, 23(1), 43. https://doi.org/10.1186/s12910-022-00782-z

Mahlobo, B., Laher, F., Smidt, W., Ogunshola, F., Khaba, T., Nkosi, T., Mbatha, A., Ngubane, T., Dong, K., Jajbhay, I., Pansegrouw, J., & Ndhlovu, Z. M. (2022). The impact of HIV infection on the frequencies, function, spatial localization and heterogeneity of T follicular regulatory cells (TFRs) within human lymph nodes. BMC Immunology, 23(1), 34. https://doi.org/10.1186/s12865-022-00508-1

Mandizvo, T., Gumede, N., Ndlovu, B., Ndlovu, S., Mann, J. K., Chopera, D. R., Singh, L., Dong, K. L., Walker, B. D., Ndhlovu, Z. M., Lavine, C. L., Seaman, M. S., Gounder, K., & Ndung’u, T. (2022). Subtle Longitudinal Alterations in Env Sequence Potentiate Differences in Sensitivity to Broadly Neutralizing Antibodies following Acute HIV-1 Subtype C Infection. Journal of Virology, e01270-22. https://doi.org/10.1128/jvi.01270-22

Marcus, M. E., Manne-Goehler, J., Theilmann, M., Farzadfar, F., Moghaddam, S. S., Keykhaei, M., Hajebi, A., Tschida, S., Lemp, J. M., Aryal, K. K., Dunn, M., Houehanou, C., Bahendeka, S., Rohloff, P., Atun, R., Bärnighausen, T. W., Geldsetzer, P., Ramirez-Zea, M., Chopra, V., … Flood, D. (2022). Use of statins for the prevention of cardiovascular disease in 41 low-income and middle-income countries: A cross-sectional study of nationally representative, individual-level data. The Lancet Global Health, 10(3), e369–e379. https://doi.org/10.1016/S2214-109X(21)00551-9

Martin, D. P., Lytras, S., Lucaci, A. G., Maier, W., Grüning, B., Shank, S. D., Weaver, S., MacLean, O. A., Orton, R. J., Lemey, P., Boni, M. F., Tegally, H., Harkins, G. W., Scheepers, C., Bhiman, J. N., Everatt, J., Amoako, D. G., San, J. E., Giandhari, J., … Kosakovsky Pond, S. L. (2022). Selection analysis identifies clusters of unusual mutational changes in Omicron lineage BA.1 that likely impact Spike function. Molecular Biology and Evolution, msac061. https://doi.org/10.1093/molbev/msac061

Matimba, A., Ali, S., Littler, K., Madden, E., Marshall, P., McCurdy, S., Nembaware, V., Rodriguez, L., Seeley, J., Tindana, P., Yakubu, A., & de Vries, J. (2022). Guideline for feedback of individual genetic research findings for genomics research in Africa. BMJ Global Health, 7(1), e007184. https://doi.org/10.1136/bmjgh-2021-007184

McCaffrey, E. F., Donato, M., Keren, L., Chen, Z., Delmastro, A., Fitzpatrick, M. B., Gupta, S., Greenwald, N. F., Baranski, A., Graf, W., Kumar, R., Bosse, M., Fullaway, C. C., Ramdial, P. K., Forgó, E., Jojic, V., Van Valen, D., Mehra, S., Khader, S. A., Bendall SC, van de Rijn M, Kalman D, Kaushal D, Hunter RL, Banaei N, Steyn AJC, Khatri P, Angelo M. (2022). The immunoregulatory landscape of human tuberculosis granulomas. Nature Immunology. https://doi.org/10.1038/s41590-021-01121-x

McCreesh, N., Karat, A. S., Govender, I., Baisley, K., Diaconu, K., Yates, T. A., Houben, R. M., Kielmann, K., Grant, A. D., & White, R. (2022). Estimating the contribution of transmission in primary healthcare clinics to community-wide TB disease incidence, and the impact of infection prevention and control interventions, in KwaZulu-Natal, South Africa. BMJ Global Health, 7(4), e007136. https://doi.org/10.1136/bmjgh-2021-007136

McCreesh, N., Mohlamonyane, M., Edwards, A., Olivier, S., Dikgale, K., Dayi, N., Gareta, D., Wood, R., Grant, A. D., White, R. G., & Middelkoop, K. (2022). Improving Estimates of Social Contact Patterns for Airborne Transmission of Respiratory Pathogens. Emerging Infectious Diseases, 28(10), 2016–2026. https://doi.org/10.3201/eid2810.212567

Meng, B., Abdullahi, A., Ferreira, I. A. T. M., Goonawardane, N., Saito, A., Kimura, I., Yamasoba, D., Gerber, P. P., Fatihi, S., Rathore, S., Zepeda, S. K., Papa, G., Kemp, S. A., Ikeda, T., Toyoda, M., Tan, T. S., Kuramochi, J., Mitsunaga, S., Ueno, T., … Gupta, R. K. (2022). Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts tropism and fusogenicity. Nature. https://doi.org/10.1038/s41586-022-04474-x

Miall, A., McLellan, R., Dong, K., Ndung’u, T., Saberi, P., Sauceda, J. A., & Dubé, K. (2022). Bringing social context into global biomedical HIV cure-related research: An urgent call to action. Journal of Virus Eradication, 8(1), 100062. https://doi.org/10.1016/j.jve.2021.100062

Millar, J. R., Bengu, N., Vieira, V. A., Adland, E., Roider, J., Muenchhoff, M., Fillis, R., Sprenger, K., Ntlantsana, V., Fatti, I., Archary, M., Groll, A., Ismail, N., García-Guerrero, M. C., Matthews, P. C., Ndung’u, T., Puertas, M. C., Martinez-Picado, J., & Goulder, P. (2021). Early initiation of antiretroviral therapy following in utero HIV infection is associated with low viral reservoirs but other factors determine viral rebound. The Journal of Infectious Diseases, 224(11), 1925–1934. https://doi.org/10.1093/infdis/jiab223

Moyano, A., Ndungu, T., & Mann, J. K. (2022). Determinants of natural HIV-1 control. Aids Reviews, 0(0), 7765. https://doi.org/10.24875/AIDSRev.21000048

Mthiyane, N., Baisley, K., Chimbindi, N., Zuma, T., Okesola, N., Dreyer, J., Herbst, C., Smit, T., Danaviah, S., McGrath, N., Harling, G., Sherr, L., Seeley, J., Floyd, S., Birdthistle, I., & Shahmanesh, M. (2022). The association of exposure to DREAMS on sexually acquiring or transmitting HIV amongst adolescent girls and young women living in rural South Africa. AIDS, 36(Supplement 1), S39–S49. https://doi.org/10.1097/QAD.0000000000003156

Mvaya, L., Khaba, T., Lakudzala, A. E., Nkosi, T., Jambo, N., Kadwala, I., Kankwatira, A., Patel, P. D., Gordon, M. A., Nyirenda, T. S., Jambo, K. C., & Ndhlovu, Z. M. (2022). Differential localization and limited cytotoxic potential of duodenal CD8+ T cells. JCI Insight, 7(3), e154195. https://doi.org/10.1172/jci.insight.154195

Nachega, J. B., Sam-Agudu, N. A., Machekano, R. N., Rabie, H., van der Zalm, M. M., Redfern, A., Dramowski, A., O’Connell, N., Pipo, M. T., Tshilanda, M. B., Byamungu, L. N., Masekela, R., Jeena, P. M., Pillay, A., Gachuno, O. W., Kinuthia, J., Ishoso, D. K., Amoako, E., Agyare, E., … Adirieje, C. (2022). Assessment of Clinical Outcomes Among Children and Adolescents Hospitalized With COVID-19 in 6 Sub-Saharan African Countries. JAMA Pediatrics, 176(3), e216436. https://doi.org/10.1001/jamapediatrics.2021.6436

Negin, J., & Seeley, J. (2021). Incidence data do not count everyone. The Lancet HIV, 8(10), e603. https://doi.org/10.1016/S2352-3018(21)00243-5

Nkosi, B., Seeley, J., Chimbindi, N., Zuma, T., Kelley, M., & Shahmanesh, M. (2022). Putting research ethics in context: Rethinking vulnerability and agency within a research ethics case study on HIV prevention for young girls in South Africa. SSM - Qualitative Research in Health, 2, 100081. https://doi.org/10.1016/j.ssmqr.2022.100081

Nkosi, T., Chasara, C., Papadopoulos, A. O., Nguni, T. L., Karim, F., Moosa, M.-Y. S., Gazy, I., Jambo, K., COMMIT-KZN, Hanekom, W., Sigal, A., & Ndhlovu, Z. M. (2022). Unsuppressed HIV infection impairs T cell responses to SARS-CoV-2 infection and abrogates T cell cross-recognition. ELife, 11, e78374. https://doi.org/10.7554/eLife.78374

Nxumalo, V., Nxumalo, S., Smit, T., Khoza, T., Mdaba, F., Khumalo, T., Cislaghi, B., McGrath, N., Seeley, J., Shahmanesh, M., & Harling, G. (2022). Protocol: Mapping social networks, social influence and sexual health among youth in rural KwaZulu-Natal, the Sixhumene cohort study. Wellcome Open Research, 7, 164. https://doi.org/10.12688/wellcomeopenres.17896.1

O’Donnell, M. R., Padayatchi, N., Wolf, A., Zelnick, J., Daftary, A., Orrell, C., Nimmo, C., Baldwin, M., Boodhram, R., Maharaj, B., Amico, K. R., Naidoo, K., & Friedland, G. (2022). Bedaquiline adherence measured by electronic dose monitoring predicts clinical outcomes in the treatment of patients with multidrug-resistant tuberculosis and HIV/AIDS. JAIDS Journal of Acquired Immune Deficiency Syndromes. https://doi.org/10.1097/QAI.0000000000002940

Ogunshola, F. J., Smidt, W., Naidoo, A. F., Nkosi, T., Ngubane, T., Khaba, T., Baiyegunhi, O. O., Mahlobo, B., Rasehlo, S., Ngema, N., Jajbhay, I., Dong, K. L., Ramsuran, V., Pansegrouw, J., Ndung’u, T., Walker, B. D., Oliveria, T. de, & Ndhlovu, Z. M. (2022). Hypermethylation at the CXCR5 gene locus limits trafficking potential of CD8+ T cells into B-cell follicles during HIV-1 infection. Blood Advances, 6(6), 1904–1916. https://doi.org/10.1182/bloodadvances.2021006001

Orievulu, K. S., Ayeb-Karlsson, S., Ngema, S., Baisley, K., Tanser, F., Ngwenya, N., Seeley, J., Hanekom, W., Herbst, K., Kniveton, D., & Iwuji, C. C. (2022). Exploring linkages between drought and HIV treatment adherence in Africa: A systematic review. The Lancet Planetary Health, 6(4), e359–e370. https://doi.org/10.1016/S2542-5196(22)00016-X

Papadopoulos, A. O., & Ndhlovu, Z. M. (2022). Editing naive CD4+ T cells. Nature methods, 19(1), 36–37. https://doi.org/10.1038/s41592-021-01332-y

Phillips, A. N., Sibanda, E., Sikwese, K., Bansi-Matharu, L., Cambiano, V., Rodger, A., Lundgren, J., Shahmanesh, M., Gilks, C., Godfrey, C., Ehrenkranz, P., Hargreaves, J. R., Revill, P., & Cowan, F. (2022). Enabling timely HIV postexposure prophylaxis access in sub-Saharan Africa. AIDS, 36(10), 1473–1475. https://doi.org/10.1097/QAD.0000000000003258

Roberts, D. A., Cuadros, D., Vandormael, A., Gareta, D., Barnabas, R. V., Herbst, K., Tanser, F., & Akullian, A. (2022). Predicting the Risk of Human Immunodeficiency Virus Type 1 (HIV-1) Acquisition in Rural South Africa Using Geospatial Data. Clinical Infectious Diseases, 75(7), 1224–1231. https://doi.org/10.1093/cid/ciac069

Roberts, D. A., Cuadros, D., Vandormael, A., Gareta, D., Barnabas, R. V., Herbst, K., Tanser, F., & Akullian, A. (2022). Predicting the risk of HIV-1 acquisition in rural South Africa using geospatial data. Clinical Infectious Diseases, ciac069. https://doi.org/10.1093/cid/ciac069

Schaefer, R., Amparo da Costa Leite, P. H., Silva, R., Abdool Karim, Q., Akolo, C., Cáceres, C. F., Dourado, I., Green, K., Hettema, A., Hoornenborg, E., Jana, S., Kerschberger, B., Mahler, H., Matse, S., McManus, H., Molina, J.-M., Reza-Paul, S., Azwa, I., Shahmanesh, M., … Dalal, S. (2022). Kidney function in tenofovir disoproxil fumarate-based oral pre-exposure prophylaxis users: A systematic review and meta-analysis of published literature and a multi-country meta-analysis of individual participant data. The Lancet HIV, 9(4), e242–e253. https://doi.org/10.1016/S2352-3018(22)00004-2

Scheepers, C., Everatt, J., Amoako, D. G., Tegally, H., Wibmer, C. K., Mnguni, A., Ismail, A., Mahlangu, B., Lambson, B. E., Martin, D. P., Wilkinson, E., San, J. E., Giandhari, J., Manamela, N., Ntuli, N., Kgagudi, P., Cele, S., Richardson, S. I., Pillay, S., … Bhiman, J. N. (2022). Emergence and phenotypic characterization of the global SARS-CoV-2 C.1.2 lineage. Nature Communications, 13(1), 1976. https://doi.org/10.1038/s41467-022-29579-9

Seaman, M. S., Siedner, M. J., Boucau, J., Lavine, C. L., Ghantous, F., Liew, M. Y., Mathews, J., Singh, A., Marino, C., Regan, J., Uddin, R., Choudhary, M. C., Flynn, J. P., Chen, G., Stuckwisch, A. M., Lipiner, T., Kittilson, A., Melberg, M., Gilbert, R. F., … Lemieux, J. E. (2022). Vaccine Breakthrough Infection with the SARS-CoV-2 Delta or Omicron (BA.1) Variant Leads to Distinct Profiles of Neutralizing Antibody Responses [Preprint]. Infectious Diseases. https://doi.org/10.1101/2022.03.02.22271731

Sigal, A. (2022). Milder disease with Omicron: Is it the virus or the pre-existing immunity? Nature Reviews Immunology. https://doi.org/10.1038/s41577-022-00678-4

Sigal, A., Milo, R., & Jassat, W. (2022). Estimating disease severity of Omicron and Delta SARS-CoV-2 infections. Nature Reviews Immunology. https://doi.org/10.1038/s41577-022-00720-5

Sithole, N., Koole, O., Sausi, K., Krows, M., Schaafsma, T., Van Heerden, A., Shahmanesh, M., van Rooyen, H., Celum, C., Barnabas, R. V., & Shapiro, A. E. (2022). Secondary Distribution of HIV Self-Testing Kits to Social and Sexual Networks of PLWH in KwaZulu-Natal, South Africa. A Brief Report. Frontiers in Public Health, 10, 855625. https://doi.org/10.3389/fpubh.2022.855625

The CRyPTIC Consortium. (2022). Epidemiological cutoff values for a 96-well broth microdilution plate for high-throughput research antibiotic susceptibility testing of M. tuberculosis. European Respiratory Journal, 2200239. https://doi.org/10.1183/13993003.00239-2022

Turkova, A., Waalewijn, H., Chan, M. K., Bollen, P. D. J., Bwakura-Dangarembizi, M. F., Kekitiinwa, A. R., Cotton, M. F., Lugemwa, A., Variava, E., Ahimbisibwe, G. M., Srirompotong, U., Mumbiro, V., Amuge, P., Zuidewind, P., Ali, S., Kityo, C. M., Archary, M., Ferrand, R. A., Violari, A., … Zuidewind, P. (2022). Dolutegravir twice-daily dosing in children with HIV-associated tuberculosis: A pharmacokinetic and safety study within the open-label, multicentre, randomised, non-inferiority ODYSSEY trial. The Lancet HIV, 9(9), e627–e637. https://doi.org/10.1016/S2352-3018(22)00160-6

van Empel, E., De Vlieg, R. A., Harling, G., Marcus, M. E., Kahn, K., Bärnighausen, T. W., Montana, L., Choko, A. T., & Manne-Goehler, J. (2022). Reaching for the ‘first 95’: A cross-country analysis of HIV self-testing in nine countries in sub-Saharan Africa. AIDS, 36(2), 297–304. https://doi.org/10.1097/QAD.0000000000003106

Walker, N., Karim, F., Moosa, M., Moodley, S., Mazibuko, M., Khan, K., Sterling, T., van der Heijden, Y., Grant, A., Elkington, P., Pym, A., & Leslie, A. (2022). Elevated Plasma Matrix Metalloproteinase-8 associates with Sputum Culture Positivity in Pulmonary Tuberculosis. The Journal of Infectious Diseases, jiac160. https://doi.org/10.1093/infdis/jiac160

Walker, T. M., Miotto, P., Köser, C. U., Fowler, P. W., Knaggs, J., Iqbal, Z., Hunt, M., Chindelevitch, L., Farhat, M. R., Cirillo, D. M., Comas, I., Posey, J., Omar, S. V., Peto, T. E., Suresh, A., Uplekar, S., Laurent, S., Colman, R. E., Nathanson, C.-M., … Puyen, Z. M. (2022). The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: A genotypic analysis. The Lancet Microbe, 3(4), e265–e273. https://doi.org/10.1016/S2666-5247(21)00301-3

Zanoni, B., Archary, M., Sibaya, T., Ramos, T., Donenberg, G., Shahmanesh, M., Celum, C., Pettifor, A., Bekker, L. G., & Haberer, J. (2022). Interventions addressing the adolescent HIV continuum of care in South Africa: A systematic review and modified Delphi analysis. BMJ Open, 12(4), e057797. https://doi.org/10.1136/bmjopen-2021-057797

Zuma, T., Seeley, J., Hlongwane, S., Chimbindi, N., Sherr, L., Floyd, S., Birdthistle, I., & Shahmanesh, M. (2022). A socio-ecological approach to understanding experiences and perceptions of a multilevel HIV prevention intervention: The determined, resilient, empowered, AIDS-free, mentored, and safe (DREAMS) partnership in uMkhanyakude, KwaZulu-Natal, South Africa. SSM - Qualitative Research in Health, 2, 100138. https://doi.org/10.1016/j.ssmqr.2022.100138

2021 Publications

Adeagbo, O., & Naidoo, K. (2021). Engaging the ‘Missing Men’ in the HIV Treatment Cascade: Creating a Tailored Intervention to Improve Men’s Uptake of HIV Care Services in Rural South Africa: A Study Protocol. International Journal of Environmental Research and Public Health, 18(7), 3709. https://doi.org/10.3390/ijerph18073709

Adriano Vieira, V., Adland, E., Malone, D. F. G., Martin, M. P., Groll, A., Ansari, M. A., Garcia-Guerrero, M. C., Puertas, M. C., Muenchhoff, M., Guash, C. F., Brander, C., Martinez-Picado, J., Bamford, A., Tudor-Williams, G., Ndung’u, T., Walker, B. D., Ramsuran, V., Frater, J., Jooste, P., … Goulder, P. J. R. (2021). An HLA-I signature favouring KIR-educated Natural Killer cells mediates immune control of HIV in children and contrasts with the HLA-B-restricted CD8+ T-cell-mediated immune control in adults. PLOS Pathogens, 17(11), e1010090. https://doi.org/10.1371/journal.ppat.1010090

Akullian, A., Vandormael, A., Miller, J.C., Bershteyn, A., Wenger, E., Cuadros, D., Gareta, D., Bärnighausen, T., Herbst, K., Tanser, F., (2021). Large age shifts in HIV-1 incidence patterns in KwaZulu-Natal, South Africa. Proc Natl Acad Sci USA, 118, e2013164118. https://doi.org/10.1073/pnas.2013164118

Asowata, O. E., Singh, A., Ngoepe, A., Herbert, N., Fardoos, R., Reddy, K., Zungu, Y., Nene, F., Mthabela, N., Ramjit, D., Karim, F., Govender, K., Ndung’u, T., Porterfield, J. Z., Adamson, J. H., Madela, F. G., Manzini, V. T., Anderson, F., Leslie, A., & Kløverpris, H. N. (2021). Irreversible depletion of intestinal CD4+ T-cells is associated with T-cell activation during chronic HIV infection. JCI Insight. https://doi.org/10.1172/jci.insight.146162

Benson, P., Litovsky, S., Steyn, A. C., Margaroli, C., Iriabho, E., & Anderson, P. (2021). Use of telepathology to facilitate COVID-19 research and education through an online COVID-19 autopsy biorepository. Journal of Pathology Informatics, 12(1), 48. https://doi.org/10.4103/jpi.jpi_15_21

Bernays, S., Lanyon, C., Tumwesige, E., Aswiime, A., Ngwenya, N., Dlamini, V., Shahmanesh, M., Seeley, J., (2021). ‘This is what is going to help me’: Developing a co-designed and theoretically informed harm reduction intervention for mobile youth in South Africa and Uganda. Global Public Health, 1–14. https://doi.org/10.1080/17441692.2021.1953105

Birdthistle, I., Carter, D. J., Mthiyane, N. T., Orindi, B. O., Muuo, S., Chimbindi, N., Ziraba, A., Shahmanesh, M., Baisley, K., & Floyd, S. (2021). Early impact of the DREAMS partnership on young women’s knowledge of their HIV status: Causal analysis of population-based surveys in Kenya and South Africa. Journal of Epidemiology and Community Health, jech-2020-216042. https://doi.org/10.1136/jech-2020-216042

Bor, J., Fischer, C., Modi, M., Richman, B., Kinker, C., King, R., Calabrese, S. K., Mokhele, I., Sineke, T., Zuma, T., Rosen, S., Bärnighausen, T., Mayer, K. H., & Onoya, D. (2021). Changing Knowledge and Attitudes Towards HIV Treatment-as-Prevention and “Undetectable = Untransmittable”: A Systematic Review. AIDS and Behavior, 25(12), 4209–4224. https://doi.org/10.1007/s10461-021-03296-8

Bozzani, F. M., Diaconu, K., Gomez, G. B., Karat, A. S., Kielmann, K., Grant, A. D., & Vassall, A. (2021). Using System Dynamics Modelling to Estimate the Costs of Relaxing Health System Constraints: A Case Study of Tuberculosis Prevention and Control Interventions in South Africa. Health Policy and Planning, czab155. https://doi.org/10.1093/heapol/czab155

Brinkmann, B., Davies, J. I., Witham, M. D., Harling, G., Bärnighausen, T., Bountogo, M., Siedner, M. J., Ouermi, L., Junghanns, J., Boubacar, C., Sié, A., Payne, C. F., & Kohler, I. V. (2021). Impairment in Activities of Daily Living and unmet need for care among older adults: A population-based study from Burkina Faso. The Journals of Gerontology: Series B, gbab041. https://doi.org/10.1093/geronb/gbab041

Bulstra, C. A., Reddy, C. L., Atun, R., Bärnighausen, T., & Hontelez, J. A. C. (2021). Impact of the COVID-19-related global recession on the financing of the global HIV response. AIDS, Publish Ahead of Print. https://doi.org/10.1097/QAD.0000000000002872

Cai, Y., Jaecklein, E., Mackenzie, J. S., Papavinasasundaram, K., Olive, A. J., Chen, X., Steyn, A. J. C., & Sassetti, C. M. (2021). Host immunity increases Mycobacterium tuberculosis reliance on cytochrome bd oxidase. PLOS Pathogens, 17(7), e1008911. https://doi.org/10.1371/journal.ppat.1008911

Cai, Y., Jaecklein, E., Mackenzie, J. S., Papavinasasundaram, K., Olive, A. J., Chen, X., Steyn, A. J. C., & Sassetti, C. M. (2021). Host immunity increases Mycobacterium tuberculosis reliance on cytochrome bd oxidase. PLOS Pathogens, 17(7), e1008911. https://doi.org/10.1371/journal.ppat.1008911

Cele, S., Gazy, I., Jackson, L., Hwa, S.-H., Tegally, H., Lustig, G., Giandhari, J., Pillay, S., Wilkinson, E., Naidoo, Y., Karim, F., Ganga, Y., Khan, K., Balazs, A. B., Gosnell, B. I., Hanekom, W., Moosa, M.-Y. S., Lessells, R. J., de Oliveira, T., & Sigal, A. (2021). Escape of SARS-CoV-2 501Y.V2 variants from neutralization by convalescent plasma. MedRxiv, 2021.01.26.21250224. https://doi.org/10.1101/2021.01.26.21250224

Cele, S., Jackson, L., Khoury, D. S., Khan, K., Moyo-Gwete, T., Tegally, H., San, J. E., Cromer, D., Scheepers, C., Amoako, D. G., Karim, F., Bernstein, M., Lustig, G., Archary, D., Smith, M., Ganga, Y., Jule, Z., Reedoy, K., Hwa, S.-H., Giandhari, J., Blackburn … Sigal, A. (2021). Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization. Nature. https://doi.org/10.1038/s41586-021-04387-1

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Mlcochova, P., Kemp, S., Dhar, M. S., Papa, G., Meng, B., Ferreira, I. A. T. M., Datir, R., Collier, D. A., Albecka, A., Singh, S., Pandey, R., Brown, J., Zhou, J., Goonawardane, N., Mishra, S., Whittaker, C., Mellan, T., Marwal, R., Datta, M., … Gupta, R. K. (2021). SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion. Nature. https://doi.org/10.1038/s41586-021-03944-y

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Mthiyane, N., Harling, G., Chimbindi, N., Baisley, K., Seeley, J., Dreyer, J., Zuma, T., Birdthistle, I., Floyd, S., McGrath, N., Tanser, F., Shahmanesh, M., & Sherr, L. (2021). Common mental disorders and HIV status in the context of DREAMS among adolescent girls and young women in rural KwaZulu-Natal, South Africa. BMC Public Health, 21(1), 478. https://doi.org/10.1186/s12889-021-10527-z

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Naidoo, K. K., Ndumnego, O. C., Ismail, N., Dong, K. L., & Ndung’u, T. (2021). Antigen Presenting Cells Contribute to Persistent Immune Activation Despite Antiretroviral Therapy Initiation During Hyperacute HIV-1 Infection. Frontiers in Immunology, 12, 738743. https://doi.org/10.3389/fimmu.2021.738743

NCD Risk Factor Collaboration (NCD-RisC), Iurilli, M. L., Zhou, B., Bennett, J. E., Carrillo-Larco, R. M., Sophiea, M. K., Rodriguez-Martinez, A., Bixby, H., Solomon, B. D., Taddei, C., Danaei, G., Di Cesare, M., Stevens, G. A., Riley, L. M., Savin, S., Cowan, M. J., Bovet, P., Damasceno, A., Chirita-Emandi, A., … Filippi, S. (2021). Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight. ELife, 10, e60060. https://doi.org/10.7554/eLife.60060

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Shahmanesh, M., Okesola, N., Chimbindi, N., Zuma, T., Mdluli, S., Mthiyane, N., Adeagbo, O., Dreyer, J., Herbst, C., McGrath, N., Harling, G., Sherr, L., Seeley, J., (2021). Thetha Nami: participatory development of a peer-navigator intervention to deliver biosocial HIV prevention for adolescents and youth in rural South Africa. BMC Public Health, 21, 1393. https://doi.org/10.1186/s12889-021-11399-z

Siedner, M. J. (2021). Ivermectin for the treatment of COVID-19 disease: Too good to pass up or too good to be true? Open Forum Infectious Diseases, ofab318. https://doi.org/10.1093/ofid/ofab318

Singer, S. N., Ndumnego, O. C., Kim, R. S., Ndung’u, T., Anastos, K., French, A., Churchyard, G., Paramithiothis, E., Kasprowicz, V. O., & Achkar, J. M. (2022). Plasma host protein biomarkers correlating with increasing Mycobacterium tuberculosis infection activity prior to tuberculosis diagnosis in people living with HIV. EBioMedicine, 75, 103787. https://doi.org/10.1016/j.ebiom.2021.103787

Singh, R., Ramsuran, V., Naranbhai, V., Yende-Zuma, N., Garrett, N., Mlisana, K., Dong, K.L., Walker, B.D., Abdool Karim, S.S., Carrington, M., Ndung’u, T. (2021). Epigenetic Regulation of BST-2 Expression Levels and the Effect on HIV-1 Pathogenesis. Front. Immunol., 12, 669241. https://doi.org/10.3389/fimmu.2021.669241

Sithole, N., Gunda, R., Koole, O., Krows, M., Schaafsma, T., Moshabela, M., Siedner, M. J., Celum, C., & Barnabas, R. V. (2021). Undisclosed Antiretroviral Therapy Use at Primary Health Care Clinics in Rural KwaZulu Natal South Africa: A DO-ART Trial Sub-study. AIDS and Behavior, 25(11), 3695–3703. https://doi.org/10.1007/s10461-021-03319-4

Sithole, N., Gunda, R., Koole, O., Krows, M., Schaafsma, T., Moshabela, M., Siedner, M.J., Celum, C., Barnabas, R.V. (2021). Undisclosed Antiretroviral Therapy Use at Primary Health Care Clinics in Rural KwaZulu Natal South Africa: A DO-ART Trial Sub-study. AIDS Behav., https://doi.org/10.1007/s10461-021-03319-4

Sithole, N., Shahmanesh, M., Koole, O., Krows, M., Schaafsma, T., Siedner, M. J., Celum, C., Barnabas, R. V., & Shapiro, A. E. (2021). Implementation of HIV Self-Testing to Reach Men in Rural uMkhanyakude, KwaZulu-Natal, South Africa. A DO-ART Trial Sub Study. Frontiers in Public Health, 9, 652887. https://doi.org/10.3389/fpubh.2021.652887

Skelly, D. T., Harding, A. C., Gilbert-Jaramillo, J., Knight, M. L., Longet, S., Brown, A., Adele, S., Adland, E., Brown, H., Medawar Laboratory Team, Chinnakannan, S., Donnison, T., Ali, M., Rongkard, P., Pace, M., Zacharopoulou, P., Robinson, N., Csala, A., De Lara, C., … James, W. S. (2021). Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern. Nature Communications, 12(1), 5061. https://doi.org/10.1038/s41467-021-25167-5

Snyman, J., Hwa, S.-H., Krause, R., Muema, D., Reddy, T., Ganga, Y., Karim, F., Leslie, A., Sigal, A., Ndung’u, T., & the COMMIT-KZN Team. (2021). Similar antibody responses against SARS-CoV-2 in HIV uninfected and infected individuals on antiretroviral therapy during the first South African infection wave. Clinical Infectious Diseases, ciab758. https://doi.org/10.1093/cid/ciab758

Snyman, J., Sanders, E. J., & Ndung’u, T. (2021). COVID-19 in Africa: Preexisting immunity and HIV. AIDS, 35(14), 2391–2393. https://doi.org/10.1097/QAD.0000000000003079

Tanser, F. C., Kim, H., Mathenjwa, T., Shahmanesh, M., Seeley, J., Matthews, P., Wyke, S., McGrath, N., Adeagbo, O., Sartorius, B., Yapa, H. M., Zuma, T., Zeitlin, A., Blandford, A., Dobra, A., & Bärnighausen, T. (2021). Home‐Based Intervention to Test and Start (HITS): A community‐randomized controlled trial to increase HIV testing uptake among men in rural South Africa. Journal of the International AIDS Society, 24(2). https://doi.org/10.1002/jia2.25665

Tegally, H., Wilkinson, E., Giovanetti, M., Iranzadeh, A., Fonseca, V., Giandhari, J., Doolabh, D., Pillay, S., San, E. J., Msomi, N., Mlisana, K., von Gottberg, A., Walaza, S., Allam, M., Ismail, A., Mohale, T., Glass, A. J., Engelbrecht, S., Van Zyl, G., l, Preiser, W., Petruccione, F., Sigal, A., Hardie, D., Marais, G., Hsiao, M., Korsman, S., Davies, M., Tyers, L., Mudau, I., York, D., Maslo, C., Goedhals, D., Abrahams, S., Laguda-Akingba, O., Alisoltani-Dehkordi, A., Godzik, A., Wibmer, C.K., Sewell, B.T., Lourenço, J., Alcantara, L.C.Jr., Pond, S.L.K., Weaver, S., Martin, D., Lessells, R.J., Bhiman, J.N., Williamson, C., … de Oliveira, T. (2021). Emergence of a SARS-CoV-2 variant of concern with mutations in spike glycoprotein. Nature. https://doi.org/10.1038/s41586-021-03402-9

Tegally, H., Wilkinson, E., Lessells, R. J., Giandhari, J., Pillay, S., Msomi, N., Mlisana, K., Bhiman, J. N., von Gottberg, A., Walaza, S., Fonseca, V., Allam, M., Ismail, A., Glass, A. J., Engelbrecht, S., Van Zyl, G., Preiser, W., Williamson, C., Petruccione, F., … de Oliveira, T. (2021). Sixteen novel lineages of SARS-CoV-2 in South Africa. Nature Medicine. https://doi.org/10.1038/s41591-021-01255-3

The CITIID-NIHR BioResource COVID-19 Collaboration, The COVID-19 Genomics UK (COG-UK) consortium, Collier, D. A., De Marco, A., Ferreira, I. A. T. M., Meng, B., Datir, R., Walls, A. C., Kemp S, S. A., Bassi, J., Pinto, D., Fregni, C. S., Bianchi, S., Tortorici, M. A., Bowen, J., Culap, K., Jaconi, S., Cameroni, E., Snell, G., … Gupta, R. K. (2021). Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies. Nature. https://doi.org/10.1038/s41586-021-03412-7

The CITIID-NIHR BioResource COVID-19 Collaboration, The COVID-19 Genomics UK (COG-UK) Consortium, Kemp, S. A., Collier, D. A., Datir, R. P., Ferreira, I. A. T. M., Gayed, S., Jahun, A., Hosmillo, M., Rees-Spear, C., Mlcochova, P., Lumb, I. U., Roberts, D. J., Chandra, A., Temperton, N., Sharrocks, K., Blane, E., Modis, Y., Leigh, K., … Gupta, R. K. (2021). SARS-CoV-2 evolution during treatment of chronic infection. Nature. https://doi.org/10.1038/s41586-021-03291-y

The NHLBI LungMap Consortium, The Human Cell Atlas Lung Biological Network, Muus, C., Luecken, M. D., Eraslan, G., Sikkema, L., Waghray, A., Heimberg, G., Kobayashi, Y., Vaishnav, E. D., Subramanian, A., Smillie, C., Jagadeesh, K. A., Duong, E. T., Fiskin, E., Triglia, E. T., Ansari, M., Cai, P., Lin, B., … Ziegler, C. G. K. (2021). Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics. Nature Medicine, 27(3), 546–559. https://doi.org/10.1038/s41591-020-01227-z

Tomita, A., Leyna, G. H., Kim, H.-Y., Moodley, Y., Mpolya, E., Mogeni, P., Cuadros, D. F., Dzomba, A., Vandormael, A., Bärnighausen, T., & Tanser, F. (2021). Patterns of multimorbidity and their association with hospitalisation: A population-based study of older adults in urban Tanzania. Age and Ageing, afab046. https://doi.org/10.1093/ageing/afab046

Tsai, A. C., Harling, G., Reynolds, Z., Gilbert, R. F., & Siedner, M. J. (2021). Coronavirus Disease 2019 (COVID-19) Transmission in the United States Before Versus After Relaxation of Statewide Social Distancing Measures. Clinical Infectious Diseases, 73(Supplement_2), S120–S126. https://doi.org/10.1093/cid/ciaa1502

Turbé, V., Herbst, C., Mngomezulu, T., Meshkinfamfard, S., Dlamini, N., Mhlongo, T., Smit, T., Cherepanova, V., Shimada, K., Budd, J., Arsenov, N., Gray, S., Pillay, D., Herbst, K., Shahmanesh, M., & McKendry, R. A. (2021). Deep learning of HIV field-based rapid tests. Nature Medicine, 10.1038/s41591-021-01384-9. Advance online publication. https://doi.org/10.1038/s41591-021-01384-9

Turkova A, White E, Mujuru HA, Kekitiinwa AR, Kityo CM, Violari A, Lugemwa A, Cressey TR, Musoke P, Variava E, Cotton MF, Archary M, Puthanakit T, Behuhuma O, Kobbe R, Welch SB, Bwakura-Dangarembizi M, Amuge P, Kaudha E, Barlow-Mosha L, Makumbi S, Ramsagar N, Ngampiyaskul C, Musoro G, Atwine L, Liberty A, Musiime V, Bbuye D, Ahimbisibwe GM, Chalermpantmetagul S, Ali S, Sarfati T, Wynne B, Shakeshaft C, Colbers A, Klein N, Bernays S, Saïdi Y, Coelho A, Grossele T, Compagnucci A, Giaquinto C, Rojo P, Ford D, Gibb DM; ODYSSEY Trial Team. (2021). Dolutegravir as First- or Second-Line Treatment for HIV-1 Infection in Children. New England Journal of Medicine, 385(27), 2531–2543. https://doi.org/10.1056/NEJMoa2108793

van Empel, E., de Vlieg, R. A., Montana, L., Gómez-Olivé, F. X., Kahn, K., Tollman, S., Berkman, L., Bärnighausen, T. W., & Manne-Goehler, J. (2021). Older Adults Vastly Overestimate Both HIV Acquisition Risk and HIV Prevalence in Rural South Africa. Archives of Sexual Behavior. https://doi.org/10.1007/s10508-021-01982-1

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Wong, E. B., Olivier, S., Gunda, R., Koole, O., Surujdeen, A., Gareta, D., Munatsi, D., Modise, T. H., Dreyer, J., Nxumalo, S., Smit, T. K., Ording-Jespersen, G., Mpofana, I. B., Khan, K., Sikhosana, Z., Moodley, S., Shen, Y. J., Khoza, T., Mhlongo, N., Bucibo, S., Nyamande K, Baisley K. J, Cuadros D, Tanser F, Grant A. D, Herbst K, Seeley J, Hanekom W.A, Ndung'u T, Siedner M. J, Pillay D; Vukuzazi Team. (2021). Convergence of infectious and non-communicable disease epidemics in rural South Africa: a cross-sectional, population-based multimorbidity study. The Lancet Global health, 9(7), e967–e976. https://doi.org/10.1016/S2214-109X(21)00176-5

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Zuma, T., King, R., Ngwenya, N., Kasujja, F. X., Chimbindi, N., Kawuma, R., Shahmanesh, M., Bernays, S., & Seeley, J. (2021). Lives Interrupted: Navigating Hardship During COVID-19 Provides Lessons in Solidarity and Visibility for Mobile Young People in South Africa and Uganda. Progress in Development Studies, 21(4), 419–434. https://doi.org/10.1177/1464993421998209

2020 Publications

Adeagbo, O., Kim, H.-Y., Tanser, F., Xulu, S., Dlamini, N., Gumede, V., Mathenjwa, T., Bärnighausen, T., McGrath, N., Blandford, A., Seeley, J., & Shahmanesh, M. (2020). Acceptability of a tablet-based application to support early HIV testing among men in rural KwaZulu-Natal, South Africa: A mixed method study. AIDS Care, 1–8. https://doi.org/10.1080/09540121.2020.1742867

Adland, E., Millar, J., Bengu, N., Muenchhoff, M., Fillis, R., Sprenger, K., Ntlantsana, V., Roider, J., Vieira, V., Govender, K., Adamson, J., Nxele, N., Ochsenbauer, C., Kappes, J., Mori, L., van Lobenstein, J., Graza, Y., Chinniah, K., Kapongo, C., … Goulder, P. (2020). Sex-specific innate immune selection of HIV-1 in utero is associated with increased female susceptibility to infection. Nature Communications, 11(1), 1767. https://doi.org/10.1038/s41467-020-15632-y

Asiimwe, S. B., Montana, L., Kahn, K., Tollman, S. M., Kabudula, C. W., Gómez-Olivé, X. F., Berkman, L. F., Glymour, M. M., & Bärnighausen, T. (2020). HIV Status and Antiretroviral Therapy as Predictors of Disability among Older South Africans: Overall Association and Moderation by Body Mass Index. Journal of Aging and Health, 089826432092532. https://doi.org/10.1177/0898264320925323

Auld, A.F., Fielding, K., Agizew, T., Maida, A., Mathoma, A., Boyd, R., Date, A., Pals, S.L., Bicego, G., Liu, Y., Shiraishi, R.W., Ehrenkranz, P., Serumola, C., Mathebula, U., Alexander, H., Charalambous, S., Emerson, C., Rankgoane-Pono, G., Pono, P., Finlay, A., Shepherd, J.C., Holmes, C., Ellerbrock, T.V., Grant, A.D., 2020. Risk scores for predicting early antiretroviral therapy mortality in sub-Saharan Africa to inform who needs intensification of care: a derivation and external validation cohort study. BMC Med 18, 311. https://doi.org/10.1186/s12916-020-01775-8

Baggett, Travis P., Justine A. Scott, Mylinh H. Le, Fatma M. Shebl, Christopher Panella, Elena Losina, Clare Flanagan, Jessie M. Gaeta, Anne Neilan, Emily P. Hyle, Amir Mohareb, Krishna P. Reddy, Mark J. Siedner, Guy Harling, Milton C. Weinstein, Andrea Ciaranello, Pooyan Kazemian, and Kenneth A. Freedberg. 2020. “Clinical Outcomes, Costs, and Cost-Effectiveness of Strategies for Adults Experiencing Sheltered Homelessness During the COVID-19 Pandemic.” JAMA Network Open 3(12):e2028195. doi: 10.1001/jamanetworkopen.2020.28195.

Barnabas, R. V., Szpiro, A. A., van Rooyen, H., Asiimwe, S., Pillay, D., Ware, N. C., Schaafsma, T. T., Krows, M. L., van Heerden, A., Joseph, P., Shahmanesh, M., Wyatt, M. A., Sausi, K., Turyamureeba, B., Sithole, N., Morrison, S., Shapiro, A. E., Roberts, D. A., Thomas, K. K., … Celum, C. (2020). Community-based antiretroviral therapy versus standard clinic-based services for HIV in South Africa and Uganda (DO ART): A randomised trial. The Lancet Global Health, 8(10), e1305–e1315. https://doi.org/10.1016/S2214-109X(20)30313-2

Barteit, S., Guzek, D., Jahn, A., Bärnighausen, T., Jorge, M. M., & Neuhann, F. (2020). Evaluation of e-learning for medical education in low- and middle-income countries: A systematic review. Computers & Education, 103726. https://doi.org/10.1016/j.compedu.2019.103726

Bbosa, N., Ssemwanga, D., Ssekagiri, A., Xi, X., Mayanja, Y., Bahemuka, U., Seeley, J., Pillay, D., Abeler-Dörner, L., Golubchik, T., Fraser, C., Kaleebu, P., & Ratmann, O. (2020). Phylogenetic and Demographic Characterization of Directed HIV-1 Transmission Using Deep Sequences from High-Risk and General Population Cohorts/Groups in Uganda. Viruses, 12(3), 331. https://doi.org/10.3390/v12030331

Bekker, L.-G., Tatoud, R., Dabis, F., Feinberg, M., Kaleebu, P., Marovich, M., Ndung’u, T., Russell, N., Johnson, J., Luba, M., Fauci, A. S., Morris, L., Pantaleo, G., Buchbinder, S., Gray, G., Vekemans, J., Kim, J. H., Levy, Y., Corey, L., … Johnston, M. I. (2020). The complex challenges of HIV vaccine development require renewed and expanded global commitment. The Lancet, 395(10221), 384–388. https://doi.org/10.1016/S0140-6736(19)32682-0

Bernays, S., Lanyon, C., Dlamini, V., Ngwenya, N., & Seeley, J. (2020). Being young and on the move in South Africa: How ‘waithood’ exacerbates HIV risks and disrupts the success of current HIV prevention interventions. Vulnerable Children and Youth Studies, 1–11. https://doi.org/10.1080/17450128.2020.1739359

Calvert, C., Marston, M., Slaymaker, E., Crampin, A. C., Price, A. J., Klein, N., Herbst, K., Michael, D., Urassa, M., Clark, S. J., Ronsmans, C., & Reniers, G. (2020). Direct maternal deaths attributable to HIV in the era of ART: Evidence from three population-based HIV cohorts with verbal autopsy. AIDS, Publish Ahead of Print. https://doi.org/10.1097/QAD.0000000000002552

Chimukuche, R. S., Wringe, A., Songo, J., Hassan, F., Luwanda, L., Kalua, T., Moshabela, M., Renju, J., & Seeley, J. (2020). Investigating the implementation of differentiated HIV services and implications for pregnant and postpartum women: A mixed methods multi-country study. Global Public Health, 1–14. https://doi.org/10.1080/17441692.2020.1795221

Cohen, K. A., Stott, K. E., Munsamy, V., Manson, A. L., Earl, A. M., & Pym, A. S. (2020). Evidence for expanding the role of streptomycin in the management of drug-resistant M. tuberculosis. Antimicrobial Agents and Chemotherapy, AAC.00860-20, aac;AAC.00860-20v1. https://doi.org/10.1128/AAC.00860-20

Collier, D. A., Assennato, S. M., Warne, B., Sithole, N., Sharrocks, K., Ritchie, A., Ravji, P., Routledge, M., Sparkes, D., Skittrall, J., Smielewska, A., Ramsey, I., Goel, N., Curran, M., Enoch, D., Tassell, R., Lineham, M., Vaghela, D., Leong, C., … Gupta, R. K. (2020). Point of care nucleic acid testing for SARS-CoV-2 in hospitalised patients: A clinical validation trial and implementation study. Cell Reports Medicine, 100062. https://www.sciencedirect.com/science/article/pii/S2666379120300781

Cork, M. A., Wilson, K. F., Perkins, S., Collison, M. L., Deshpande, A., Eaton, J. W., Earl, L., Haeuser, E., Justman, J. E., Kinyoki, D. K., Mayala, B. K., Mosser, J. F., Murray, C. J. L., Nkengasong, J. N., Piot, P., Sartorius, B., Schaeffer, L. E., Serfes, A. L., Sligar, A., … Dwyer-Lindgren, L. (2020). Mapping male circumcision for HIV prevention efforts in sub-Saharan Africa. BMC Medicine, 18(1), 189. https://doi.org/10.1186/s12916-020-01635-5

Cumming, B. M., Reddy, V. P., & Steyn, A. J. C. (2020). The Analysis of Mycobacterium tuberculosis-Induced Bioenergetic Changes in Infected Macrophages Using an Extracellular Flux Analyzer. In S. Mishra (Ed.), Immunometabolism (Vol. 2184, pp. 161–184). Springer US. https://doi.org/10.1007/978-1-0716-0802-9_12

Dambach, P., Mahenge, B., Mashasi, I., Muya, A., Barnhart, D. A., Bärnighausen, T. W., Spiegelman, D., & Harling, G. (2020). Socio-demographic characteristics and risk factors for HIV transmission in female bar workers in sub-Saharan Africa: A systematic literature review. BMC Public Health, 20(1), 697. https://doi.org/10.1186/s12889-020-08838-8

Dube, A., Renju, J., Wamoyi, J., Hassan, F., Seeley, J., Chimukuche, R. S., Songo, J., Kalua, T., Crampin, A., Moshabela, M., & Wringe, A. (2020). Consequences of male partner engagement policies on HIV care-seeking in three African countries: Findings from the SHAPE UTT study. Global Public Health, 1–11. https://doi.org/10.1080/17441692.2020.1805788

Dunlap, M. D., Prince, O. A., Rangel-Moreno, J., Thomas, K. A., Scordo, J. M., Torrelles, J. B., Cox, J., Steyn, A. J. C., Zúñiga, J., Kaushal, D., & Khader, S. A. (2020). Formation of Lung Inducible Bronchus Associated Lymphoid Tissue Is Regulated by Mycobacterium tuberculosis Expressed Determinants. Frontiers in Immunology, 11, 1325. https://doi.org/10.3389/fimmu.2020.01325

Edwards, A., Siedner, M. J., Nash, S., Neuman, M., Danaviah, S., Smit, T., Gareta, D., Kowal, P., & Seeley, J. (2020). HIV serostatus, inflammatory biomarkers and the frailty phenotype among older people in rural KwaZulu-Natal, South Africa. African Journal of AIDS Research: AJAR, 1–9. https://doi.org/10.2989/16085906.2020.1790398

Edwards, T., Mkwanazi, N., Mitchell. J, Bland, R.M., &Rochat, T.J. (2020). Empowering parents for human immunodeficiency virus prevention: Health and sex education at home. S Afr J HIV Med. 21(1). https://doi.org/10.4102/sajhivmed.v21i1.970

El Bouzidi, K., Kemp, S. A., Datir, R. P., Murtala-Ibrahim, F., Aliyu, A., Kwaghe, V., Frampton, D., Roy, S., Breuer, J., Sabin, C. A., Ogbanufe, O., Charurat, M. E., Bonsall, D., Golubchik, T., Fraser, C., Dakum, P., Ndembi, N., & Gupta, R. K. (2020). High prevalence of integrase mutation L74I in West African HIV-1 subtypes prior to integrase inhibitor treatment. Journal of Antimicrobial Chemotherapy, dkaa033. https://doi.org/10.1093/jac/dkaa033

Fernández-García, M., Rey-Stolle, F., Boccard, J., Reddy, V. P., García, A., Cumming, B. M., Steyn, A. J. C., Rudaz, S., & Barbas, C. (2020). Comprehensive Examination of the Mouse Lung Metabolome Following Mycobacterium tuberculosis Infection Using a Multiplatform Mass Spectrometry Approach. Journal of Proteome Research, acs.jproteome.9b00868. https://doi.org/10.1021/acs.jproteome.9b00868

Ferreira, I. A. T. M., Porterfield, J. Z., Gupta, R. K., & Mlcochova, P. (2020). Cell Cycle Regulation in Macrophages and Susceptibility to HIV-1. Viruses, 12(8), 839. https://doi.org/10.3390/v12080839

Garay-Baquero, D. J., White, C. H., Walker, N. F., Tebruegge, M., Schiff, H. F., Ugarte-Gil, C., Morris-Jones, S., Marshall, B. G., Manousopoulou, A., Adamson, J. H., Vallejo, A. F., Bielecka, M. K., Wilkinson, R. J., Tezera, L. B., Woelk, C. H., Garbis, S. D., & Elkington, P. (2020). Comprehensive plasma proteomic profiling reveals biomarkers for active tuberculosis. JCI Insight. https://doi.org/10.1172/jci.insight.137427

Geldsetzer, P., Reinmuth, M., Ouma, P. O., Lautenbach, S., Okiro, E. A., Baernighausen, T., & Zipf, A. (2020). Mapping physical access to healthcare for older adults in sub-Saharan Africa: A cross-sectional analysis with implications for the COVID-19 response [Preprint]. Public and Global Health. https://doi.org/10.1101/2020.07.17.20152389

Graham, S. M., Agutu, C., van der Elst, E., Hassan, A. S., Gichuru, E., Mugo, P. M., Farquhar, C., Babigumira, J. B., Goodreau, S. M., Hamilton, D. T., Ndung’u, T., Sirengo, M., Chege, W., & Sanders, E. J. (2020). A Novel HIV-1 RNA Testing Intervention to Detect Acute and Prevalent HIV Infection in Young Adults and Reduce HIV Transmission in Kenya: Protocol for a Randomized Controlled Trial. JMIR Research Protocols, 9(8), e16198. https://doi.org/10.2196/16198

Grant, A. D., Charalambous, S., Tlali, M., Karat, A. S., Dorman, S. E., Hoffmann, C. J., Johnson, S., Vassall, A., Churchyard, G. J., & Fielding, K. L. (2020). Algorithm-guided empirical tuberculosis treatment for people with advanced HIV (TB Fast Track): An open-label, cluster-randomised trial. The Lancet HIV, 7(1), e27–e37. https://doi.org/10.1016/S2352-3018(19)30266-8

Gupta, R. K., Peppa, D., Hill, A. L., Gálvez, C., Salgado, M., Pace, M., McCoy, L. E., Griffith, S. A., Thornhill, J., Alrubayyi, A., Huyveneers, L. E. P., Nastouli, E., Grant, P., Edwards, S. G., Innes, A. J., Frater, J., Nijhuis, M., Wensing, A. M. J., Martinez-Picado, J., & Olavarria, E. (2020). Evidence for HIV-1 cure after CCR5Δ32/Δ32 allogeneic haemopoietic stem-cell transplantation 30 months post analytical treatment interruption: A case report. The Lancet HIV, S2352301820300692. https://doi.org/10.1016/S2352-3018(20)30069-2

Haber, N. A., Lesko, C. R., Fox, M. P., Powers, K. A., Harling, G., Edwards, J., Salomon, J., Lippman, S. A., Bor, J., Chang, A. Y., Anglemyer, A., & Pettifor, A. (2020). Limitations of the UNAIDS 90-90-90 metrics: A simulation-based comparison of cross-sectional and longitudinal metrics for the HIV care continuum. AIDS, 1. https://doi.org/10.1097/QAD.0000000000002502

Harling, G., Kobayashi, L. C., Farrell, M. T., Wagner, R. G., Tollman, S., & Berkman, L. (2020). Social contact, social support, and cognitive health in a population-based study of middle-aged and older men and women in rural South Africa. Social Science & Medicine, 260, 113167. https://doi.org/10.1016/j.socscimed.2020.113167

Havlir, D., Lockman, S., Ayles, H., Larmarange, J., Chamie, G., Gaolathe, T., Iwuji, C., Fidler, S., Kamya, M., Floyd, S., Moore, J., Hayes, R., Petersen, M., Dabis, F., & on behalf of the (Universal Test, Treat Trials) UT3 Consortium. (2020). What do the Universal Test and Treat trials tell us about the path to HIV epidemic control? Journal of the International AIDS Society, 23(2). https://doi.org/10.1002/jia2.25455

Hunter, Jessica, Sandile Cele, Laurelle Jackson, Jennifer Giandhari, Tulio de Oliveira, Gila Lustig, and Alex Sigal. 2020. HIV Cell-to-Cell Spread Slows Evolution of Drug Resistance. preprint. Evolutionary Biology. https://www.biorxiv.org/content/10.1101/2020.09.04.283192v1.full

Iwuji, C., Chimukuche, R. S., Zuma, T., Plazy, M., Larmarange, J., Orne-Gliemann, J., Siedner, M., Shahmanesh, M., & Seeley, J. (2020). Test but not treat: Community members’ experiences with barriers and facilitators to universal antiretroviral therapy uptake in rural KwaZulu-Natal, South Africa. PLOS ONE, 15(9), e0239513. https://doi.org/10.1371/journal.pone.0239513

Iwuji, C., Shahmanesh, M., Koole, O., Herbst, K., Pillay, D., Siedner, M., Baisley, K., & H‐DREAM Network. (2020). Clinical outcomes after first‐line HIV treatment failure in South Africa: The next cascade of care. HIV Medicine, hiv.12877. https://doi.org/10.1111/hiv.12877

Jennewein, M. F., Mabuka, J., Papia, C. L., Boudreau, C. M., Dong, K. L., Ackerman, M. E., Ndung’u, T., & Alter, G. (2020). Tracking the Trajectory of Functional Humoral Immune Responses Following Acute HIV Infection. Frontiers in Immunology, 11, 1744. https://doi.org/10.3389/fimmu.2020.01744

Jin, S. W., Mwimanzi, F. M., Mann, J. K., Bwana, M. B., Lee, G. Q., Brumme, C. J., Hunt, P. W., Martin, J. N., Bangsberg, D. R., Ndung’u, T., Brumme, Z. L., & Brockman, M. A. (2020). Variation in HIV-1 Nef function within and among viral subtypes reveals genetically separable antagonism of SERINC3 and SERINC5. PLoS Pathogens, 16(9), e1008813. https://doi.org/10.1371/journal.ppat.1008813

Kasprowicz, V. O., Chopera, D., Waddilove, K. D., Brockman, M. A., Gilmour, J., Hunter, E., Kilembe, W., Karita, E., Gaseitsiwe, S., Sanders, E. J., & Ndung’u, T. (2020). African-led health research and capacity building- is it working? BMC Public Health, 20(1), 1104. https://doi.org/10.1186/s12889-020-08875-3

Kazer, S. W., Aicher, T. P., Muema, D. M., Carroll, S. L., Ordovas-Montanes, J., Miao, V. N., Tu, A. A., Ziegler, C. G. K., Nyquist, S. K., Wong, E. B., Ismail, N., Dong, M., Moodley, A., Berger, B., Love, J. C., Dong, K. L., Leslie, A., Ndhlovu, Z. M., Ndung’u, T., … Shalek, A. K. (2020). Integrated single-cell analysis of multicellular immune dynamics during hyperacute HIV-1 infection. Nature Medicine. https://doi.org/10.1038/s41591-020-0799-2

Kielmann, K., Karat, A. S., Zwama, G., Colvin, C., Swartz, A., Voce, A. S., Yates, T. A., MacGregor, H., McCreesh, N., Kallon, I., Vassall, A., Govender, I., Seeley, J., & Grant, A. D. (2020). Tuberculosis infection prevention and control: Why we need a whole systems approach. Infectious Diseases of Poverty, 9(1), 56. https://doi.org/10.1186/s40249-020-00667-6

Kim, H.-Y., Dobra, A., & Tanser, F. (2020). Migration and first-year maternal mortality among HIV-positive postpartum women: A population-based longitudinal study in rural South Africa. PLOS Medicine, 17(3), e1003085. https://doi.org/10.1371/journal.pmed.1003085

Kim, H., Harling, G., Vandormael, A., Tomita, A., Cuadros, D. F., Bärnighausen, T., & Tanser, F. (2020). HIV seroconcordance among heterosexual couples in rural KwaZulu‐Natal, South Africa: A population‐based analysis. Journal of the International AIDS Society, 23(1). https://doi.org/10.1002/jia2.25432

Kim, H., Miller, F. D., Hernandez, A., Tanser, F., Mogeni, P., & Cuadros, D. F. (2020). Spatiotemporal analysis of insecticide-treated net use for children under 5 in relation to socioeconomic gradients in Central and East Africa. Malaria Journal, 19(1), 163. https://doi.org/10.1186/s12936-020-03236-2

Kinyanjui, S., Fonn, S., Kyobutungi, C., Vicente-Crespo, M., Bonfoh, B., Ndungu, T., Sewankambo, N. K., Djimde, A. A., Gaye, O., Chirwa, T., Musenge, E., Elliot, A., Nakanjako, D., Chibanda, D., & Awandare, G. (2020). Enhancing science preparedness for health emergencies in Africa through research capacity building. BMJ Global Health, 5(7), e003072. https://doi.org/10.1136/bmjgh-2020-003072

Lanyon, C., Seeley, J., Namukwaya, S., Musiime, V., Paparini, S., Nakyambadde, H., Matama, C., Turkova, A., & Bernays, S. (2020). “Because we all have to grow up”: Supporting adolescents in Uganda to develop core competencies to transition towards managing their HIV more independently. Journal of the International AIDS Society, 23(S5). https://doi.org/10.1002/jia2.25552

Lee, Bei Shi, Kiel Hards, Curtis A. Engelhart, Erik J. Hasenoehrl, Nitin P. Kalia, Jared S. Mackenzie, Ekaterina Sviriaeva, Shi Min Sherilyn Chong, Malathy Sony S. Manimekalai, Vanessa H. Koh, John Chan, Jiayong Xu, Sylvie Alonso, Marvin J. Miller, Adrie J. C. Steyn, Gerhard Grüber, Dirk Schnappinger, Michael Berney, Gregory M. Cook, Garrett C. Moraski, and Kevin Pethe. 2020. “Dual Inhibition of the Terminal Oxidases Eradicates Antibiotic-Tolerant Mycobacterium Tuberculosis.” EMBO Molecular Medicine e13207. doi: 10.15252/emmm.202013207.

Lupien, A., Foo, C. S.-Y., Savina, S., Vocat, A., Piton, J., Monakhova, N., Benjak, A., Lamprecht, D. A., Steyn, A. J. C., Pethe, K., Makarov, V. A., & Cole, S. T. (2020). New 2-Ethylthio-4-methylaminoquinazoline derivatives inhibiting two subunits of cytochrome bc1 in Mycobacterium tuberculosis. PLOS Pathogens, 16(1), e1008270. https://doi.org/10.1371/journal.ppat.1008270

Mann, J. K., Rajkoomar, E., Jin, S. W., Mkhize, Q., Baiyegunhi, O., Mbona, P., Brockman, M. A., & Ndung’u, T. (2020). Consequences of HLA‐associated mutations in HIV‐1 subtype C Nef on HLA‐I down‐regulation ability. Journal of Medical Virology, jmv.25676. https://doi.org/10.1002/jmv.25676

Mbano, I. M., Mandizvo, T., Rogich, J., Kunota, T. T. R., Mackenzie, J. S., Pillay, M., & Balagaddé, F. K. (2020). Light Forge: A Microfluidic DNA Melting-based Tuberculosis Test. The Journal of Applied Laboratory Medicine, 5(3), 440–453. https://doi.org/10.1093/jalm/jfaa019

McCreesh, N., Grant, A. D., Yates, T. A., Karat, A. S., & White, R. G. (2020). Tuberculosis from transmission in clinics in high HIV settings may be far higher than contact data suggest. The International Journal of Tuberculosis and Lung Disease: The Official Journal of the International Union Against Tuberculosis and Lung Disease, 24(4), 403–408. https://doi.org/10.5588/ijtld.19.0410

McCreesh, Nicky, Vuyiswa Dlamini, Anita Edwards, Stephen Olivier, Njabulo Dayi, Keabetswe Dikgale, Siyabonga Nxumalo, Jaco Dreyer, Kathy Baisley, Mark J. Siedner, Richard G. White, Kobus Herbst, Alison D. Grant, and Guy Harling. 2020. Impact of Social Distancing Regulations and Epidemic Risk Perception on Social Contact and SARS-CoV-2 Transmission Potential in Rural South Africa: Analysis of Repeated Cross-Sectional Surveys. preprint. Public and Global Health. https://www.medrxiv.org/content/10.1101/2020.12.01.20241877v1.full

Millar, J. R., Bengu, N., Fillis, R., Sprenger, K., Ntlantsana, V., Vieira, V. A., Khambati, N., Archary, M., Muenchhoff, M., Groll, A., Grayson, N., Adamson, J., Govender, K., Dong, K., Kiepiela, P., Walker, B. D., Bonsall, D., Connor, T., Bull, M. J., … Goulder, P. (2020). HIGH-FREQUENCY failure of combination antiretroviral therapy in paediatric HIV infection is associated with unmet maternal needs causing maternal NON-ADHERENCE. EClinicalMedicine, 22, 100344. https://doi.org/10.1016/j.eclinm.2020.100344

Mlcochova, P., Collier, D., Ritchie, A., Assennato, S. M., Hosmillo, M., Goel, N., Meng, B., Chatterjee, K., Mendoza, V., Temperton, N., Kiss, L., James, L. C., Ciazynska, K. A., Xiong, X., Briggs, J. A. G., Nathan, J. A., Mescia, F., Bergamaschi, L., Zhang, H., … Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID BioResource Collaboration. (2020). Combined Point-of-Care Nucleic Acid and Antibody Testing for SARS-CoV-2 following Emergence of D614G Spike Variant. Cell Reports. Medicine, 1(6), 100099. https://doi.org/10.1016/j.xcrm.2020.100099

Mlcochova, P., Winstone, H., Zuliani-Alvarez, L., & Gupta, R. K. (2020). TLR4-Mediated Pathway Triggers Interferon-Independent G0 Arrest and Antiviral SAMHD1 Activity in Macrophages. Cell Reports, 30(12), 3972-3980.e5. https://doi.org/10.1016/j.celrep.2020.03.008

Mogeni, P., Vandormael, A., Cuadros, D., Appleton, C., & Tanser, F. (2020). Impact of community piped water coverage on re-infection with urogenital schistosomiasis in rural South Africa. ELife, 9, e54012. https://doi.org/10.7554/eLife.54012

Molatlhegi, R. P., Liebenberg, L. J., Leslie, A., Noel-Romas, L., Mabhula, A., Mchunu, N., Perner, M., Birse, K., Ngcapu, S., Adamson, J. H., Govender, K., Garrett, N. J., Samsunder, N., Burgener, A. D., Abdool Karim, S. S., Abdool Karim, Q., Passmore, J.-A. S., & McKinnon, L. R. (2020). Plasma concentration of injectable contraceptive correlates with reduced cervicovaginal growth factor expression in South African women. Mucosal Immunology. https://doi.org/10.1038/s41385-019-0249-y

Moosa, Y., Kwon, D., de Oliveira, T., & Wong, E. B. (2020). Determinants of Vaginal Microbiota Composition. Frontiers in Cellular and Infection Microbiology, 10, 467. https://doi.org/10.3389/fcimb.2020.00467

Moyano, A., Lustig, G., Rodel, H. E., Antal, T., & Sigal, A. (2020). Interference with HIV infection of the first cell is essential for viral clearance at sub-optimal levels of drug inhibition. PLOS Computational Biology, 16(2), e1007482. https://doi.org/10.1371/journal.pcbi.1007482

Mthiyane, T., Millard, J., Adamson, J., Balakrishna, Y., Connolly, C., Owen, A., Rustomjee, R., Dheda, K., McIlleron, H., & Pym, A. S. (2020). N-acetyltransferase 2 genotypes amongst Zulu Speaking South Africans and isoniazid/ N -acetyl-isoniazid pharmacokinetics during anti-tuberculosis treatment. Antimicrobial Agents and Chemotherapy, AAC.02376-19, aac;AAC.02376-19v1. https://doi.org/10.1128/AAC.02376-19

Muema, D. M., Akilimali, N. A., Ndumnego, O. C., Rasehlo, S. S., Durgiah, R., Ojwach, D. B. A., Ismail, N., Dong, M., Moodley, A., Dong, K. L., Ndhlovu, Z. M., Mabuka, J. M., Walker, B. D., Mann, J. K., & Ndung’u, T. (2020). Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection. BMC Medicine, 18(1), 81. https://doi.org/10.1186/s12916-020-01529-6

Muema, D. M., Mthembu, M., Schiff, A. E., Singh, U., Corleis, B., Chen, D., Bassett, T., Rasehlo, S. S., Nyamande, K., Khan, D. F., Maharaj, P., Mitha, M., Suleman, M., Mhlane, Z., Naidoo, T., Ramjit, D., Karim, F., Kwon, D. S., Ndung’u, T., & Wong, E. B. (2020). Contrasting Inflammatory Signatures in Peripheral Blood and Bronchoalveolar Cells Reveal Compartment-Specific Effects of HIV Infection. Frontiers in Immunology, 11, 864. https://doi.org/10.3389/fimmu.2020.00864

Muenchhoff, M., A. W. Chung, J. Roider, Anne-Sophie Dugast, Simone Richardson, Henrik Kløverpris, Alasdair Leslie, Thumbi Ndung’u, Penny Moore, Galit Alter, and Philip J. R. Goulder. 2020. “Distinct Immunoglobulin Fc Glycosylation Patterns Are Associated with Disease Nonprogression and Broadly Neutralizing Antibody Responses in Children with HIV Infection.” MSphere 5(6). doi: 10.1128/mSphere.00880-20

Naicker, N., Sigal, A., & Naidoo, K. (2020). Metformin as Host-Directed Therapy for TB Treatment: Scoping Review. Frontiers in Microbiology, 11, 435. https://doi.org/10.3389/fmicb.2020.00435

Nakasone, S. E., Chimbindi, N., Mthiyane, N., Nkosi, B., Zuma, T., Baisley, K., Dreyer, J., Pillay, D., Floyd, S., Birdthistle, I., Seeley, J., & Shahmanesh, M. (2020). “They have this not care – don’t care attitude:” A Mixed Methods Study Evaluating Community Readiness for Oral PrEP in Adolescent Girls and Young Women in a Rural Area of South Africa. AIDS Research and Therapy, 17(1), 55. https://doi.org/10.1186/s12981-020-00310-2

Narayanan, G. A., McLaren, J. E., Meermeier, E. W., Ladell, K., Swarbrick, G. M., Price, D. A., Tran, J. G., Worley, A. H., Vogt, T., Wong, E. B., & Lewinsohn, D. M. (2020). The MAIT TCRβ chain contributes to discrimination of microbial ligand. Immunology & Cell Biology, imcb.12370. https://doi.org/10.1111/imcb.12370

Ndlovu, B., Gounder, K., Muema, D., Raju, N., Hermanus, T., Mthethwa, Q., Robertson, K., Walker, B. D., Georgiev, I. S., Morris, L., Moore, P. L., & Ndung’u, T. (2020a). Envelope characteristics in individuals who developed neutralizing antibodies targeting different epitopes in HIV-1 subtype C infection. Virology, 546, 1–12. https://doi.org/10.1016/j.virol.2020.03.003

Ndlovu, L. N., Peetluk, L., Moodley, S., Nhamoyebonde, S., Ngoepe, A. T., Mazibuko, M., Khan, K., Karim, F., Pym, A. S., Maruri, F., Moosa, M.-Y. S., van der Heijden, Y. F., Sterling, T. R., & Leslie, A. (2020). Increased Neutrophil Count and Decreased Neutrophil CD15 Expression Correlate With TB Disease Severity and Treatment Response Irrespective of HIV Co-infection. Frontiers in Immunology, 11, 1872. https://doi.org/10.3389/fimmu.2020.01872

Ngwenya, N., Nkosi, B., Mchunu, L. S., Ferguson, J., Seeley, J., & Doyle, A. M. (2020). Behavioural and socio-ecological factors that influence access and utilisation of health services by young people living in rural KwaZulu-Natal, South Africa: Implications for intervention. PLOS ONE, 15(4), e0231080. https://doi.org/10.1371/journal.pone.0231080

Nimmo, C., Brien, K., Millard, J., Grant, A. D., Padayatchi, N., Pym, A. S., O’Donnell, M., Goldstein, R., Breuer, J., & Balloux, F. (2020). Dynamics of within-host Mycobacterium tuberculosis diversity and heteroresistance during treatment. EBioMedicine, 55, 102747. https://doi.org/10.1016/j.ebiom.2020.102747

Nimmo, C., Millard, J., Brien, K., Moodley, S., van Dorp, L., Lutchminarain, K., Wolf, A., Grant, A. D., Balloux, F., Pym, A. S., Padayatchi, N., & O’Donnell, M. (2020). Bedaquiline resistance in drug-resistant tuberculosis HIV co-infected patients. European Respiratory Journal, 1902383. https://doi.org/10.1183/13993003.02383-2019

Nimmo, C., Millard, J., van Dorp, L., Brien, K., Moodley, S., Wolf, A., Grant, A. D., Padayatchi, N., Pym, A. S., Balloux, F., & O’Donnell, M. (2020). Population-level emergence of bedaquiline and clofazimine resistance-associated variants among patients with drug-resistant tuberculosis in southern Africa: A phenotypic and phylogenetic analysis. The Lancet Microbe, 1(4), e165–e174. https://doi.org/10.1016/S2666-5247(20)30031-8

Nyakato, P., Davies, M.-A., Technau, K.-G., Fatti, G., Rabie, H., Tanser, F., Boulle, A., Wood, R., Eley, B., Sawry, S., Giddy, J., Sipambo, N., Kuhn, L., Fairlie, L., & for the International epidemiology Database to Evaluate AIDS-Southern Africa (IeDEA-SA) Collaboration. (2020). Virologic response to efavirenz-based first-line antiretroviral therapy in children with previous exposure to antiretrovirals to prevent mother-to-child transmission. PLOS ONE, 15(5), e0233693. https://doi.org/10.1371/journal.pone.0233693

Ogongo, P., Steyn, A. J. C., Karim, F., Dullabh, K. J., Awala, I., Madansein, R., Leslie, A., & Behar, S. M. (2019). Differential skewing of donor-unrestricted and γδ T cell repertoires in tuberculosis-infected human lungs. Journal of Clinical Investigation, 130(1), 214–230. https://doi.org/10.1172/JCI130711

Phillips, A. N., Bansi-Matharu, L., Venter, F., Havlir, D., Pozniak, A., Kuritzkes, D. R., Wensing, A., Lundgren, J. D., Pillay, D., Mellors, J., Cambiano, V., Jahn, A., Apollo, T., Mugurungi, O., Ripin, D., Da Silva, J., Raizes, E., Ford, N., Siberry, G. K., … Bertagnolio, S. (2020). Updated assessment of risks and benefits of dolutegravir versus efavirenz in new antiretroviral treatment initiators in sub-Saharan Africa: Modelling to inform treatment guidelines. The Lancet HIV, S235230181930400X. https://doi.org/10.1016/S2352-3018(19)30400-X

Pillay, T., Cornell, M., Fox, M. P., Euvrard, J., Fatti, G., Technau, K.-G., Sipambo, N., Prozesky, H., Eley, B., Tanser, F., & Johnson, L. F. (2020). Recording of HIV viral loads and viral suppression in South African patients receiving antiretroviral treatment: A multicentre cohort study. Antiviral Therapy. https://doi.org/10.3851/IMP3371

Pillaye, J. N., Marakalala, M. J., Khumalo, N., Spearman, W., & Ndlovu, H. (2020). Mechanistic insights into antiretroviral drug‐induced liver injury. Pharmacology Research & Perspectives, 8(4). https://doi.org/10.1002/prp2.598

Rahman, Md. A., Cumming, B. M., Addicott, K. W., Pacl, H. T., Russell, S. L., Nargan, K., Naidoo, T., Ramdial, P. K., Adamson, J. H., Wang, R., & Steyn, A. J. C. (2020). Hydrogen sulfide dysregulates the immune response by suppressing central carbon metabolism to promote tuberculosis. Proceedings of the National Academy of Sciences, 117(12), 6663–6674. https://doi.org/10.1073/pnas.1919211117

Reddy, K. P., Shebl, F. M., Foote, J. H. A., Harling, G., Scott, J. A., Panella, C., Flanagan, C., Hyle, E. P., Neilan, A. M., Mohareb, A. M., Bekker, L.-G., Lessells, R. J., Ciaranello, A. L., Wood, R., Losina, E., Freedberg, K. A., Kazemian, P., & Siedner, M. J. (2020). Cost-effectiveness of public health strategies for COVID-19 epidemic control in South Africa [Preprint]. Public and Global Health. https://doi.org/10.1101/2020.06.29.20140111

Renju, J., Rice, B., Songo, J., Hassan, F., Chimukuche, R. S., McLean, E., Kalua, T., Kajoka, D., Geubbels, E., Moshabela, M., Seeley, J., & Wringe, A. (2020). Influence of evolving HIV treatment guidance on CD4 counts and viral load monitoring: A mixed-methods study in three African countries. Global Public Health, 1–17. https://doi.org/10.1080/17441692.2020.1805785

Rosenberg, M., Gómez‐Olivé, F. X., Wagner, R. G., Rohr, J., Payne, C. F., Berkman, L., Kahn, K., Tollman, S., Bärnighausen, T., & Kobayashi, L. C. (2020). The relationships between cognitive function, literacy and HIV status knowledge among older adults in rural South Africa. Journal of the International AIDS Society, 23(3). https://doi.org/10.1002/jia2.25457

Saini, V., Chinta, K. C., Reddy, V. P., Glasgow, J. N., Stein, A., Lamprecht, D. A., Rahman, Md. A., Mackenzie, J. S., Truebody, B. E., Adamson, J. H., Kunota, T. T. R., Bailey, S. M., Moellering, D. R., Lancaster, J. R., & Steyn, A. J. C. (2020). Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis. Nature Communications, 11(1), 557. https://doi.org/10.1038/s41467-019-14132-y

Shapiro, A. E., Heerden, A., Krows, M., Sausi, K., Sithole, N., Schaafsma, T. T., Koole, O., Rooyen, H., Celum, C. L., & Barnabas, R. V. (2020). An implementation study of oral and blood‐based HIV self‐testing and linkage to care among men in rural and peri‐urban KwaZulu‐Natal, South Africa. Journal of the International AIDS Society, 23(S2). https://doi.org/10.1002/jia2.25514

Siedner, M. J., Baisley, K., Koole, O., Mpofana, I., Ording-Jespersen, G., Matthews, P., Herbst, K., Smit, T., & Pillay, D. (2020). Does antiretroviral therapy use affect the accuracy of HIV rapid diagnostic assays? Experience from a demographic health and surveillance site in rural South Africa. Diagnostic Microbiology and Infectious Disease, 115031. https://doi.org/10.1016/j.diagmicrobio.2020.115031

Siedner, M. J., Harling, G., Derache, A., Smit, T., Khoza, T., Gunda, R., Mngomezulu, T., Gareta, D., Majozi, N., Ehlers, E., Dreyer, J., Nxumalo, S., Dayi, N., Ording-Jesperson, G., Ngwenya, N., Wong, E., Iwuji, C., Shahmanesh, M., Seeley, J., … Herbst, K. (2020). Protocol: Leveraging a demographic and health surveillance system for Covid-19 Surveillance in rural KwaZulu-Natal. Wellcome Open Research, 5, 109. https://doi.org/10.12688/wellcomeopenres.15949.1

Siedner, M. J., Kraemer, J. D., Meyer, M. J., Harling, G., Mngomezulu, T., Gabela, P., Dlamini, S., Gareta, D., Majozi, N., Ngwenya, N., Reynolds, Z., Seeley, J., Wong, E., Iwuji, C., Shahmanesh, M., Hanekom, W., & Herbst, K. (2020). Access to primary healthcare during lockdown measures for COVID-19 in rural South Africa: A longitudinal cohort study [Preprint]. Health Systems and Quality Improvement. https://doi.org/10.1101/2020.05.15.20103226

Singh, A., Kazer, S. W., Roider, J., Krista, K. C., Millar, J., Asowata, O. E., Ngoepe, A., Ramsuran, D., Fardoos, R., Ardain, A., Muenchhoff, M., Kuhn, W., Karim, F., Ndung’u, T., Shalek, A. K., Goulder, P., Leslie, A., & Kløverpris, H. N. (2020). Innate Lymphoid Cell Activation and Sustained Depletion in Blood and Tissue of Children Infected with HIV from Birth Despite Antiretroviral Therapy. Cell Reports, 32(11), 108153. https://doi.org/10.1016/j.celrep.2020.108153

Suchard, M. S., Adu-Gyamfi, C. G., Cumming, B. M., & Savulescu, D. M. (2020). Evolutionary Views of Tuberculosis: Indoleamine 2,3-Dioxygenase Catalyzed Nicotinamide Synthesis Reflects Shifts in Macrophage Metabolism: Indoleamine 2,3-Dioxygenase Reflects Altered Macrophage Metabolism During Tuberculosis Pathogenesis. BioEssays: News and Reviews in Molecular, Cellular and Developmental Biology, 42(5), e1900220. https://doi.org/10.1002/bies.201900220

Sweeney, S., Vassall, A., Guinness, L., Siapka, M., Chimbindi, N., Mudzengi, D., & Gomez, G. B. (2020). Examining Approaches to Estimate the Prevalence of Catastrophic Costs Due to Tuberculosis from Small-Scale Studies in South Africa. PharmacoEconomics. https://doi.org/10.1007/s40273-020-00898-3

Tanser, F., Kim, H.-Y., Vandormael, A., Iwuji, C., & Bärnighausen, T. (2020). Opportunities and Challenges in HIV Treatment as Prevention Research: Results from the ANRS 12249 Cluster-Randomized Trial and Associated Population Cohort. Current HIV/AIDS Reports. https://doi.org/10.1007/s11904-020-00487-1

Tezera, L. B., Bielecka, M. K., Ogongo, P., Walker, N. F., Ellis, M., Garay-Baquero, D. J., Thomas, K., Reichmann, M. T., Johnston, D. A., Wilkinson, K. A., Ahmed, M., Jogai, S., Jayasinghe, S. N., Wilkinson, R. J., Mansour, S., Thomas, G. J., Ottensmeier, C. H., Leslie, A., & Elkington, P. T. (2020). Anti-PD-1 immunotherapy leads to tuberculosis reactivation via dysregulation of TNF-α. ELife, 9, e52668. https://doi.org/10.7554/eLife.52668

Tlali, M., Fielding, K. L., Karat, A. S., Hoffmann, C. J., Muravha, T., Grant, A. D., & Charalambous, S. (2020). Sensitivity of the lateral flow urine lipoarabinomannan assay in ambulant adults with advanced HIV disease: Data from the TB Fast Track study. Transactions of The Royal Society of Tropical Medicine and Hygiene, 114(8), 556–560. https://doi.org/10.1093/trstmh/traa018

Tomita, A., Cuadros, D. F., Mabhaudhi, T., Sartorius, B., Ncama, B. P., Dangour, A. D., Tanser, F., Modi, A. T., Slotow, R., & Burns, J. K. (2020). Spatial clustering of food insecurity and its association with depression: A geospatial analysis of nationally representative South African data, 2008–2015. Scientific Reports, 10(1), 13771. https://doi.org/10.1038/s41598-020-70647-1

Umviligihozo, G., Cobarrubias, K. D., Chandrarathna, S., Jin, S. W., Reddy, N., Byakwaga, H., Muzoora, C., Bwana, M. B., Lee, G. Q., Hunt, P. W., Martin, J. N., Brumme, C. J., Bangsberg, D. R., Karita, E., Allen, S., Hunter, E., Ndung’u, T., Brumme, Z. L., & Brockman, M. A. (2020). Differential Vpu-Mediated CD4 and Tetherin Downregulation Functions among Major HIV-1 Group M Subtypes. Journal of Virology, 94(14), e00293-20, /jvi/94/14/JVI.00293-20.atom. https://doi.org/10.1128/JVI.00293-20

Vandormael, A., Cuadros, D., Dobra, A., Bärnighausen, T., & Tanser, F. (2020). HIV incidence declines in a rural South African population: A G-imputation approach for inference. BMC Public Health, 20(1), 1205. https://doi.org/10.1186/s12889-020-09193-4

Vandormael, A., Cuadros, D., Kim, H.-Y., Bärnighausen, T., & Tanser, F. (2020). The state of the HIV epidemic in rural KwaZulu-Natal, South Africa: A novel application of disease metrics to assess trajectories and highlight areas for intervention. International Journal of Epidemiology, dyz269. https://doi.org/10.1093/ije/dyz269

Vandormael, Alain, Maya Adam, Merlin Greuel, and Till Bärnighausen. 2020. “An Entertainment-Education Approach to Prevent COVID-19 Spread: Study Protocol for a Multi-Site Randomized Controlled Trial.” Trials 21(1):1025. doi: 10.1186/s13063-020-04942-7.

Yapa, H. M., Drayne, R., Klein, N., De Neve, J.-W., Petoumenos, K., Jiamsakul, A., Herbst, C., Pillay, D., Post, F. A., & Bärnighausen, T. (2020). Infant feeding knowledge and practice vary by maternal HIV status: A nested cohort study in rural South Africa. International Breastfeeding Journal, 15(1), 77. https://doi.org/10.1186/s13006-020-00317-5

Zaniewski, E., Dao Ostinelli, C. H., Chammartin, F., Maxwell, N., Davies, M., Euvrard, J., Dijk, J., Bosomprah, S., Phiri, S., Tanser, F., Sipambo, N., Muhairwe, J., Fatti, G., Prozesky, H., Wood, R., Ford, N., Fox, M. P., & Egger, M. (2020). Trends in CD4 and viral load testing 2005 to 2018: Multi‐cohort study of people living with HIV in Southern Africa. Journal of the International AIDS Society, 23(7). https://doi.org/10.1002/jia2.25546

Ziegler, C. G. K., Allon, S. J., Nyquist, S. K., Mbano, I. M., Miao, V. N., Tzouanas, C. N., Cao, Y., Yousif, A. S., Bals, J., Hauser, B. M., Feldman, J., Muus, C., Wadsworth, M. H., Kazer, S. W., Hughes, T. K., Doran, B., Gatter, G. J., Vukovic, M., Taliaferro, F., … Zhang, K. (2020). SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues. Cell, 181(5), 1016-1035.e19. https://doi.org/10.1016/j.cell.2020.04.035

2019 Publications

Abeler-Dörner, L., Grabowski, M. K., Rambaut, A., Pillay, D., & Fraser, C. (2019). PANGEA-HIV 2: Phylogenetics And Networks for Generalised Epidemics in Africa. Current Opinion in HIV and AIDS, 14(3), 173–180. https://doi.org/10.1097/COH.0000000000000542

Adam, M., McMahon, S. A., Prober, C., & Bärnighausen, T. (2019). Human-Centered Design of Video-Based Health Education: An Iterative, Collaborative, Community-Based Approach. Journal of Medical Internet Research, 21(1), e12128. https://doi.org/10.2196/12128

Adam, M., Tomlinson, M., Le Roux, I., LeFevre, A. E., McMahon, S. A., Johnston, J., … Bärnighausen, T. (2019). The Philani MOVIE study: a cluster-randomized controlled trial of a mobile video entertainment-education intervention to promote exclusive breastfeeding in South Africa. BMC Health Services Research, 19(1), 211. https://doi.org/10.1186/s12913-019-4000-x

Adeagbo, O. A., Mthiyane, N., Herbst, C., Mee, P., Neuman, M., Dreyer, J., Chimbindi, N., Smit, T., Okesola, N., Johnson, C., Hatzold, K., Seeley, J., Cowan, F., Corbett, L., & Shahmanesh, M. (2019). Cluster randomised controlled trial to determine the effect of peer delivery HIV self-testing to support linkage to HIV prevention among young women in rural KwaZulu-Natal, South Africa: A study protocol. BMJ Open, 9(12), e033435. https://doi.org/10.1136/bmjopen-2019-033435

Adeagbo, O., Herbst, C., Blandford, A., McKendry, R., Estcourt, C., Seeley, J., Shahmanesh, M., 2019. Exploring People’s Candidacy for Mobile Health–Supported HIV Testing and Care Services in Rural KwaZulu-Natal, South Africa: Qualitative Study. J Med Internet Res 21, e15681. https://doi.org/10.2196/15681

Akilimali, N. A., Muema, D. M., Specht, C., Chang, C. C., Moosa, M.-Y. S., Levitz, S. M., … Ndung’u, T. (2019). Cryptococcosis-associated Immune Reconstitution Inflammatory Syndrome is associated with Dysregulation of IL-7/IL-7 Receptor Signaling Pathway in T-cells and Monocyte Activation: JAIDS Journal of Acquired Immune Deficiency Syndromes, 1. https://doi.org/10.1097/QAI.0000000000001946

Ardain, A., Domingo-Gonzalez, R., Das, S., Kazer, S. W., Howard, N. C., Singh, A., … Khader, S. A. (2019). Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis. Nature, 570(7762), 528–532. https://doi.org/10.1038/s41586-019-1276-2

Ardain, A., Marakalala, M.J., Leslie, A., 2019. Tissue‐resident innate immunity in the lung. Immunology imm.13143. https://doi.org/10.1111/imm.13143

Ardain, A., Porterfield, J. Z., Kløverpris, H. N., & Leslie, A. (2019). Type 3 ILCs in Lung Disease. Frontiers in Immunology, 10. https://doi.org/10.3389/fimmu.2019.00092

Baisley, K., Seeley, J., Siedner, M., Koole, K., Matthews, P., Tanser, F., …, Shahmanesh, M. (2019). Findings from home‐based HIV testing and facilitated linkage after scale‐up of test and treat in rural South Africa: Young people still missing. HIV Medicine, hiv.12787. https://doi.org/10.1111/hiv.12787

Barnhart, D. A., Harling, G., Muya, A., Ortblad, K. F., Mashasi, I., Dambach, P., … Spiegelman, D. (2019). Structural, interpersonal, psychosocial, and behavioral risk factors for HIV acquisition among female bar workers in Dar es Salaam, Tanzania. AIDS Care, 1–10. https://doi.org/10.1080/09540121.2019.1612018

Barteit, S., Guzek, D., Jahn, A., Bärnighausen, T., Jorge, M. M., & Neuhann, F. (2019). Evaluation of e-learning for medical education in low- and middle-income countries: A systematic review. Computers & Education, 103726. https://doi.org/10.1016/j.compedu.2019.103726

Barteit, S., Jahn, A., Banda, S. S., Bärnighausen, T., Bowa, A., Chileshe, G., … Neuhann, F. (2019). E-Learning for Medical Education in Sub-Saharan Africa and Low-Resource Settings: Viewpoint. Journal of Medical Internet Research, 21(1), e12449. https://doi.org/10.2196/12449

Barteit, S., Neuhann, F., Bärnighausen, T., Lüders, S., Malunga, G., Chileshe, G., … Jahn, A. (2019). Perspectives of Nonphysician Clinical Students and Medical Lecturers on Tablet-Based Health Care Practice Support for Medical Education in Zambia, Africa: Qualitative Study. JMIR MHealth and UHealth, 7(1), e12637. https://doi.org/10.2196/12637

Barton, J. P., Rajkoomar, E., Mann, J. K., Murakowski, D. K., Toyoda, M., Mahiti, M., … Ndung’u, T. (2019). Modelling and in vitro testing of the HIV-1 Nef fitness landscape. Virus Evolution, 5(2), vez029–vez029. https://doi.org/10.1093/ve/vez029

Baschieri, A., Gordeev, V. S., Akuze, J., Kwesiga, D., Blencowe, H., Cousens, S., … Lawn, J. E. (2019). “Every Newborn-INDEPTH” (EN-INDEPTH) study protocol for a randomised comparison of household survey modules for measuring stillbirths and neonatal deaths in five Health and Demographic Surveillance sites. Journal of Global Health, 9(1). https://doi.org/10.7189/jogh.09.010901

Bekker, L.-G., Tatoud, R., Dabis, F., Feinberg, M., Kaleebu, P., Marovich, M., … Johnston, M. I. (2019). The complex challenges of HIV vaccine development require renewed and expanded global commitment. The Lancet, S0140673619326820. https://doi.org/10.1016/S0140-6736(19)32682-0

Birdthistle, I., Tanton, C., Tomita, A., Graaf, K. de, Schaffnit, S. B., Tanser, F., & Slaymaker, E. (2019). Recent levels and trends in HIV incidence rates among adolescent girls and young women in ten high-prevalence African countries: A systematic review and meta-analysis. The Lancet Global Health, 7(11), e1521–e1540. https://doi.org/10.1016/S2214-109X(19)30410-3

Bixby, H., Bentham, J., Zhou, B., Di Cesare, M., Paciorek, C. J., Bennett, J. E., …Gareta,D.,..Tanser,F.,.. NCD Risk Factor Collaboration (NCD-RisC). (2019). Rising rural body-mass index is the main driver of the global obesity epidemic in adults. Nature, 569(7755), 260–264. https://doi.org/10.1038/s41586-019-1171-x

Chimukangara, B., Lessells, R. J., Rhee, S.-Y., Giandhari, J., Kharsany, A. B. M., Naidoo, K., … de Oliveira, T. (2019). Trends in Pretreatment HIV-1 Drug Resistance in Antiretroviral Therapy-naive Adults in South Africa, 2000–2016: A Pooled Sequence Analysis. EClinicalMedicine. https://doi.org/10.1016/j.eclinm.2019.03.006

Closson, K., Dietrich, J. J., Beksinska, M., Gibbs, A., Hornschuh, S., Smith, T., … Kaida, A. (2019). Measuring sexual relationship power equity among young women and young men South Africa: Implications for gender-transformative programming. PLOS ONE, 14(9), e0221554. https://doi.org/10.1371/journal.pone.0221554

Concannon, D., Herbst, K., & Manley, E. (2019). Developing a Data Dashboard Framework for Population Health Surveillance: Widening Access to Clinical Trial Findings. JMIR Formative Research, 3(2), e11342. https://doi.org/10.2196/11342

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Witham, M. D., Davies, J. I., Bärnighausen, T., Bountogo, M., Manne-Goehler, J., Payne, C. F., … Harling, G. (2019). Frailty and physical performance in the context of extreme poverty: A population-based study of older adults in rural Burkina Faso. Wellcome Open Research, 4, 135. https://doi.org/10.12688/wellcomeopenres.15455.1

Wong, E. B., Gold, M. C., Meermeier, E. W., Xulu, B. Z., Khuzwayo, S., Sullivan, Z. A., … Lewinsohn, D. M. (2019). TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis. Communications Biology, 2(1), 203. https://doi.org/10.1038/s42003-019-0442-2

Wood, C. S., Thomas, M. R., Budd, J., Mashamba-Thompson, T. P., Herbst, K., Pillay, D., … Stevens, M. M. (2019). Taking connected mobile-health diagnostics of infectious diseases to the field. Nature, 566(7745), 467–474. https://doi.org/10.1038/s41586-019-0956-2

Yang, Y., McKhann, A., Chen, S., Harling, G., & Onnela, J.-P. (2019). Efficient vaccination strategies for epidemic control using network information. Epidemics, 27, 115–122. https://doi.org/10.1016/j.epidem.2019.03.002

Zhang, Y., Bärnighausen, T., & Eyal, N. (2019). Appropriate Health Resource Rationing in a Non-Ideal World: JAIDS Journal of Acquired Immune Deficiency Syndromes, 1. https://doi.org/10.1097/QAI.0000000000002127

Zhang, Y., Bärnighausen, T., & Eyal, N. (2019). When Global ART Budgets Cannot Cover All Patients, Who Should Be Eligible?: JAIDS Journal of Acquired Immune Deficiency Syndromes, 1. https://doi.org/10.1097/QAI.0000000000002017

2018 Publications

Ahmed, S., Autrey, J., Katz, I. T., Fox, M. P., Rosen, S., Onoya, D., … Bor, J. (2018). Why do people living with HIV not initiate treatment? A systematic review of qualitative evidence from low- and middle-income countries. Social Science & Medicine. https://doi.org/10.1016/j.socscimed.2018.05.048

Attaf, M., Malik, A., Severinsen, M.C., Roider, J., Ogongo, P., Buus, S., Ndung’u, T., Leslie, A., Kløverpris, H.N., Matthews, P.C., Sewell, A.K., Goulder, P. (2018). Major TCR Repertoire Perturbation by Immunodominant HLA-B*44:03-Restricted CMV-Specific T Cells. Frontiers in Immunology, 9. https://doi.org/10.3389/fimmu.2018.02539

Baisley, K., Chimbindi, N., Mthiyane, N., Floyd, S., McGrath, N., Pillay, D., … Shahmanesh, M. (2018). High HIV incidence and low uptake of HIV prevention services: The context of risk for young male adults prior to DREAMS in rural KwaZulu-Natal, South Africa. PLOS ONE, 13(12), e0208689. https://doi.org/10.1371/journal.pone.0208689

Baiyegunhi, O., Ndlovu, B., Ogunshola, F., Ismail, N., Walker, B. D., Ndung’u, T., & Ndhlovu, Z. M. (2018). Frequencies of circulating Th1-biased T follicular helper cells in acute HIV-1 infection correlate with the development of HIV-specific antibody responses and lower set point viral load. Journal of Virology, JVI.00659-18. https://doi.org/10.1128/JVI.00659-18

Barichievy, S., Naidoo, J., Boulle, M., Scholefield, J., Parihar, S. P., Coussens, A. K., … Mhlanga, M. M. (2017). Viral apoptosis evasion via the MAPK pathway by use of a host long noncoding RNA. https://doi.org/10.1101/153130

Beteck, R. M., Seldon, R., Coertzen, D., van der Watt, M. E., Reader, J., Mackenzie, J. S., … Haynes, R. K. (2018). Accessible and distinct decoquinate derivatives active against Mycobacterium tuberculosis and apicomplexan parasites. Communications Chemistry, 1(1). https://doi.org/10.1038/s42004-018-0062-7

Birdthistle, I., Schaffnit, S. B., Kwaro, D., Shahmanesh, M., Ziraba, A., Kabiru, C. W., … Floyd, S. (2018). Evaluating the impact of the DREAMS partnership to reduce HIV incidence among adolescent girls and young women in four settings: a study protocol. BMC Public Health, 18(1).https://doi.org/10.1186/s12889-018-5789-7 https://doi.org/10.1186/s12889-018-5789-7

Bommer, C., Sagalova, V., Heesemann, E., Manne-Goehler, J., Atun, R., Bärnighausen, T., … Vollmer, S. (2018). Global Economic Burden of Diabetes in Adults: Projections From 2015 to 2030. Diabetes Care, dc171962. https://doi.org/10.2337/dc17-1962

Bond, V., Ngwenya, F., Murray, E., Ngwenya, N., Viljoen, L., Gumede, D., … Seeley, J. (2018). Value and Limitations of Broad Brush Surveys Used in Community-Randomized Trials in Southern Africa. Qualitative Health Research, 1049732318809940. https://doi.org/10.1177/1049732318809940

Brennan, A. T., Bor, J., Davies, M.-A., Wandeler, G., Prozesky, H., Fatti, G., … Fox, M. P. (2018). Drug Side Effects and Retention on HIV Treatment: a Regression Discontinuity Study of Tenofovir Implementation in South Africa and Zambia. American Journal of Epidemiology. https://doi.org/10.1093/aje/kwy093

Camlin, C. S., Cassels, S., & Seeley, J. (2018). Bringing population mobility into focus to achieve HIV prevention goals. Journal of the International AIDS Society, 21(S4), e25136. https://doi.org/10.1002/jia2.25136

Chang, A. Y., Haber, N., Bärnighausen, T., Herbst, K., Gareta, D., Pillay, D., & Salomon, J. A. (2018). Improving the validity of mathematical models for HIV elimination by incorporating empirical estimates of progression through the HIV treatment cascade: JAIDS Journal of Acquired Immune Deficiency Syndromes, https://doi.org/10.1097/QAI.0000000000001852

Chang, S. T., Chihota, V. N., Fielding, K. L., Grant, A. D., Houben, R. M., White, R. G., … Wagner, B. G. (2018). Small contribution of gold mines to the ongoing tuberculosis epidemic in South Africa: a modeling-based study. BMC Medicine, 16(1). https://doi.org/10.1186/s12913-018-3404-3

Chetty, T., Yapa, H. M. N., Herbst, C., Geldsetzer, P., Naidu, K. K., … Bärnighausen, T. (2018). The MONARCH intervention to enhance the quality of antenatal and postnatal primary health services in rural South Africa: protocol for a stepped-wedge cluster-randomised controlled trial. BMC Health Services Research, 18(1). https://doi.org/10.1186/s12913-018-3404-3

Chimbindi, N., Birdthistle, I., Shahmanesh, M., Osindo, J., Mushati, P., Ondeng’e, K., … Seeley, J. (2018). Translating DREAMS into practice: Early lessons from implementation in six settings. PLOS ONE, 13(12), e0208243. https://doi.org/10.1371/journal.pone.0208243

Chimbindi, N., Mthiyane, N., Birdthistle, I., Floyd, S., McGrath, N., Pillay, D., … Shahmanesh, M. (2018). Persistently high incidence of HIV and poor service uptake in adolescent girls and young women in rural KwaZulu-Natal, South Africa prior to DREAMS. PLOS ONE, 13(10), e0203193. https://doi.org/10.1371/journal.pone.0203193

Chimukangara, B., Kharsany, A. B., Lessells, R. J., Naidoo, K., Rhee, S.-Y., Manasa, J., ….Pillay, D, de Oliveira, T. (2018). Moderate to high levels of pre-treatment HIV drug resistance in KwaZulu-Natal Province, South Africa. AIDS Research and Human Retroviruses. https://doi.org/10.1089/AID.2018.0202

Chinta, K. C., Rahman, M. A., Saini, V., Glasgow, J. N., Reddy, V. P., Lever, J. M., … Steyn, A. J. C. (2018). Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis. Cell Reports, 25(7), 1938-1952.e5. https://doi.org/10.1016/j.celrep.2018.10.073

Chung, A., Makuba, J. M., Ndlovu, B., Licht, A., Robinson, H., Ramlakhan, Y., … Alter, G. (2018). Viral control in chronic HIV-1 subtype C infection is associated with enrichment of p24 IgG1 with Fc effector activity: AIDS, 1. https://doi.org/10.1097/QAD.0000000000001812

Collier, D., Haddow, L., Brijkumar, J., Moosa, M.-Y., Benjamin, L., & Gupta, R. (2018). HIV Cerebrospinal Fluid Escape and Neurocognitive Pathology in the Era of Combined Antiretroviral Therapy: What Lies Beneath the Tip of the Iceberg in Sub-Saharan Africa? Brain Sciences, 8(10), 190. https://doi.org/10.3390/brainsci8100190

Coltart, C. E. M., Hoppe, A., Parker, M., Dawson, L., Amon, J. J., Simwinga, M., … Zimmerman, R. (2018). Ethical considerations in global HIV phylogenetic research. The Lancet HIV. https://doi.org/10.1016/S2352-3018(18)30134-6

Cumming, B. M., Addicott, K. W., Adamson, J. H., & Steyn, A. J. (2018). Mycobacterium tuberculosis induces decelerated bioenergetic metabolism in human macrophages. ELife, 7. https://doi.org/10.7554/eLife.39169

De Neve, J.-W., Karlsson, O., Coetzee, L., Schröder, H., Subramanian, S., Bärnighausen, T., & Vollmer, S. (2018). Antiretroviral therapy coverage associated with increased co-residence between elderly people and prime-age adults in Africa: AIDS, 1. https://doi.org/10.1097/QAD.0000000000001917

Deiner, M. S., Keenan, J. D., Diarra, A., Sié, A., Zongo, A., Millogo, O., … Chodosh, J. (2018). Seasonal and Temporal Trends in Childhood Conjunctivitis in Burkina Faso. The American Journal of Tropical Medicine and Hygiene. https://doi.org/10.4269/ajtmh.17-0642

Derache, A., Iwuji, C. C., Baisley, K., Danaviah, S., Marcelin, A.-G., Calvez, V., … Pillay, D. (2018). Impact of next generation sequencing defined HIV pre-treatment drug resistance on virological outcomes in the ANRS 12249 treatment as prevention trial. Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciy881

Derache, A., Iwuji, C.C., Danaviah, S., Giandhari, J., Marcelin, A.-G., Calvez, V., de Oliveira, T., Dabis, F., Pillay, D., Gupta, R.K. (2018). Predicted antiviral activity of tenofovir versus abacavir in combination with a cytosine analogue and the integrase inhibitor dolutegravir in HIV-1-infected South African patients initiating or failing first-line ART. Journal of Antimicrobial Chemotherapy. https://doi.org/10.1093/jac/dky428

Dong, K. L., Moodley, A., Kwon, D. S., Ghebremichael, M. S., Dong, M., Ismail, N., … Ndung’u, T. (2018). Detection and treatment of Fiebig stage I HIV-1 infection in young at-risk women in South Africa: a prospective cohort study. The Lancet HIV, 5(1), e35–e44. https://doi.org/10.1016/S2352-3018(17)30146-7

Doyle, A. M., Floyd, S., Baisley, K., Orindi, B., Kwaro, D., Mthiyane, T. N., … Birdthistle, I. (2018). Who are the male sexual partners of adolescent girls and young women? Comparative analysis of population data in three settings prior to DREAMS roll-out. PLOS ONE, 13(9), e0198783. https://doi.org/10.1371/journal.pone.0198783

Dzomba, A., Govender, K., Mashamba-Thompson, T. P., & Tanser, F. (2018). Mobility and increased risk of HIV acquisition in South Africa: a mixed-method systematic review protocol. Systematic Reviews, 7(1). https://doi.org/10.1186/s13643-018-0703-z

Ekoru, K., Young, E. H., Dillon, D. G., Gurdasani, D., Stehouwer, N., Faurholt-Jepsen, D., … Sandhu, M. S. (2018). HIV treatment is associated with a twofold higher probability of raised triglycerides: pooled analyses in 21 023 individuals in sub-Saharan Africa. Global Health, Epidemiology and Genomics, 3. https://doi.org/10.1017/gheg.2018.7

Foo, C. S., Lupien, A., Kienle, M., Vocat, A., Benjak, A., Sommer, R., … Cole, S. T. (2018). Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis. MBio, 9(5). https://doi.org/10.1128/mBio.01276-18

Francis, S. C., Mthiyane, T. N., Baisley, K., Mchunu, S. L., Ferguson, J. B., Smit, T., … Shahmanesh, M. (2018). Prevalence of sexually transmitted infections among young people in South Africa: A nested survey in a health and demographic surveillance site. PLOS Medicine, 15(2), e1002512. https://doi.org/10.1371/journal.pmed.1002512

Frank, D. J., Horne, D. J., Dutta, N. K., Shaku, M. T., Madensein, R., Hawn, T. R., … Tanvir, Z. (2018). Remembering the Host in Tuberculosis Drug Development. The Journal of Infectious Diseases. https://doi.org/10.1093/infdis/jiy712

Geldsetzer, P., Francis, J. M., Sando, D., Asmus, G., Lema, I. A., Mboggo, E., … Bärnighausen, T. (2018). Community delivery of antiretroviral drugs: A non-inferiority cluster-randomized pragmatic trial in Dar es Salaam, Tanzania. PLOS Medicine, 15(9), e1002659. https://doi.org/10.1371/journal.pmed.1002659

Geldsetzer, P., Manne-Goehler, J., Theilmann, M., Davies, J. I., Awasthi, A., Vollmer, S., … Atun, R. (2018). Diabetes and Hypertension in India: A Nationally Representative Study of 1.3 Million Adults. JAMA Internal Medicine. https://doi.org/10.1001/jamainternmed.2017.8094

Geldsetzer, P., Manne-Goehler, J., Theilmann, M., Davies, J. I., Awasthi, A., Danaei, G., … Atun, R. (2018). Geographic and sociodemographic variation of cardiovascular disease risk in India: A cross-sectional study of 797,540 adults. PLOS Medicine, 15(6), e1002581. https://doi.org/10.1371/journal.pmed.1002581

Geldsetzer, P., Vaikath, M., Wagner, R., Rohr, J. K., Montana, L., Gómez-Olivé, F. X., … Berkman, L. F. (2018). Depressive Symptoms and their Relation to Age and Chronic diseases among middle-aged and Older Adults in rural South Africa. The Journals of Gerontology: Series A. https://doi.org/10.1093/gerona/gly145

Ginsburg, C., Bocquier, P., Béguy, D., Afolabi, S., Kahn, K., Obor, D., … Collinson, M. A. (2018). Association between internal migration and epidemic dynamics: an analysis of cause-specific mortality in Kenya and South Africa using health and demographic surveillance data. BMC Public Health, 18(1). https://doi.org/10.1186/s12889-018-5851-5

Günthard, H. F., Calvez, V., Paredes, R., Pillay, D., Shafer, R. W., Wensing, A. M., … Richman, D. D. (2018). Human Immunodeficiency Virus Drug Resistance: 2018 Recommendations of the International Antiviral Society–USA Panel. Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciy463

Haber, N., Harling, G., Cohen, J., Mutevedzi, T., Tanser, F., Gareta, D., … Fink, G. (2018). List randomization for eliciting HIV status and sexual behaviors in rural KwaZulu-Natal, South Africa: a randomized experiment using known true values for validation. BMC Medical Research Methodology, 18(1). https://doi.org/10.1186/s12874-018-0507-9

Harling, G., Gumede, D., Shahmanesh, M., Pillay, D., Bärnighausen, T. W., & Tanser, F. (2018). Sources of social support and sexual behaviour advice for young adults in rural South Africa. BMJ Global Health, 3(6), e000955. https://doi.org/10.1136/bmjgh-2018-000955

Hontelez, J. A. C., Bor, J., Tanser, F. C., Pillay, D., Moshabela, M., & Bärnighausen, T. (2018). HIV Treatment Substantially Decreases Hospitalization Rates: Evidence From Rural South Africa. Health Affairs, 37(6), 997–1004. https://doi.org/10.1377/hlthaff.2017.0820

Hu, J., Geldsetzer, P., Steele, S. J., Matthews, P., Ortblad, K., Solomon, T., … Bärnighausen, T. (2018). The impact of lay counselors on HIV testing rates: Quasi-experimental evidence from lay counselor redeployment in KwaZulu-Natal, South Africa. AIDS, 1. https://doi.org/10.1097/QAD.0000000000001924

Iwuji, C., McGrath, N., Calmy, A., Dabis, F., Pillay, D., Newell, M.-L., … Porter, K. (2018). Universal test and treat is not associated with sub-optimal antiretroviral therapy adherence in rural South Africa: the ANRS 12249 TasP trial. Journal of the International AIDS Society, 21(6), e25112. https://doi.org/10.1002/jia2.25112

Kaida, A., Dietrich, J. J., Laher, F., Beksinska, M., Jaggernath, M., Bardsley, M., … Gray, G. (2018). A high burden of asymptomatic genital tract infections undermines the syndromic management approach among adolescents and young adults in South Africa: implications for HIV prevention efforts. BMC Infectious Diseases, 18(1). https://doi.org/10.1186/s12879-018-3380-6

Karat, A. S., Maraba, N., Tlali, M., Charalambous, S., Chihota, V. N., Churchyard, G. J., … Grant, A. D. (2018). Performance of verbal autopsy methods in estimating HIV-associated mortality among adults in South Africa. BMJ Global Health, 3(4), e000833. https://doi.org/10.1136/bmjgh-2018-000833

Kim, J. T., Chang, E., Sigal, A., & Baltimore, D. (2018). Dendritic cells efficiently transmit HIV to T Cells in a tenofovir and raltegravir insensitive manner. PLOS ONE, 13(1), e0189945. https://doi.org/10.1371/journal.pone.0189945

Kluberg, S. A., Fox, M. P., LaValley, M., Pillay, D., Bärnighausen, T., & Bor, J. (2018). Do ART eligibility expansions crowd out the sickest? Evidence from rural South Africa. Tropical Medicine & International Health. https://doi.org/10.1111/tmi.13122

Kufa, T., Fielding, K. L., Hippner, P., Kielmann, K., Vassall, A., Churchyard, G. J., … Charalambous, S. (2018). An intervention to optimise the delivery of integrated tuberculosis and HIV services at primary care clinics: results of the MERGE cluster randomised trial. Contemporary Clinical Trials, 72, 43–52. https://doi.org/10.1016/j.cct.2018.07.013

Larmarange, J., Diallo, M. H., McGrath, N., Iwuji, C., Plazy, M., Thiébaut, R., … the ANRS 12249 TasP Study Group. (2018). The impact of population dynamics on the population HIV care cascade: results from the ANRS 12249 Treatment as Prevention trial in rural KwaZulu-Natal (South Africa). Journal of the International AIDS Society, 21, e25128. https://doi.org/10.1002/jia2.25128

Liu, Y., Ndumnego, O., Chen, T., Kim, R., Jenny-Avital, E., Ndung’u, T., … Achkar, J. (2018). Soluble CD14 as a Diagnostic Biomarker for Smear-Negative HIV-Associated Tuberculosis. Pathogens, 7(1), 26. https://doi.org/10.3390/pathogens7010026

Lozano, R., Fullman, N., Abate, D., Abay, S. M., Abbafati, C., Abbasi, N., …Tanser, F., Bärnighausen T…. Murray, C. J. L. (2018). Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet, 392(10159), 2091–2138. https://doi.org/10.1016/S0140-6736(18)32281-5

Manne-Goehler, J., Rohr, J., Montana, L., Siedner, M., Harling, G., Gómez-Olivé, F. X., … Bärnighausen, T. W. (2018). ART Denial: Results of a Home-Based Study to Validate Self-reported Antiretroviral Use in Rural South Africa. AIDS and Behavior. https://doi.org/10.1007/s10461-018-2351-7

Maraba, N., Chihota, V., McCarthy, K., Churchyard, G. J., & Grant, A. D. (2018). Linkage to care among adults being investigated for tuberculosis in South Africa: pilot study of a case manager intervention. BMJ Open, 8(5), e021111. https://doi.org/10.1136/bmjopen-2017-021111

McCarthy, K., Fielding, K., Churchyard, G. J., & Grant, A. D. (2018). Empiric tuberculosis treatment in South African primary health care facilities - for whom, where, when and why: Implications for the development of tuberculosis diagnostic tests. PLOS ONE, 13(1), e0191608. https://doi.org/10.1371/journal.pone.0191608

McGovern, M., Canning, D., & Bärnighausen, T. (2018). Accounting for non-response bias using participation incentives and survey design: An application using gift vouchers. Economics Letters. https://doi.org/10.1016/j.econlet.2018.07.040

Meyer-Rath, G., McGillen, J. B., Cuadros, D. F., Hallett, T. B., Bhatt, S., Wabiri, N., … Rehle, T. (2018). Targeting the right interventions to the right people and places: the role of geospatial analysis in HIV programme planning. AIDS, 1. https://doi.org/10.1097/QAD.0000000000001792

Moazen, B., Saeedi Moghaddam, S., Silbernagl, M. A., Lotfizadeh, M., Bosworth, R. J., Alammehrjerdi, Z., … Dolan, K. A. (2018). Prevalence of Drug Injection, Sexual Activity, Tattooing, and Piercing Among Prison Inmates. Epidemiologic Reviews, mxy002–mxy002. https://doi.org/10.1093/epirev/mxy002

Mori, M., Leitman, E., Walker, B., Ndung’u, T., Carrington, M., & Goulder, P. (2018). Impact of HLA allele-KIR pairs on HIV clinical outcome in South Africa. The Journal of Infectious Diseases. https://doi.org/10.1093/infdis/jiy692

Mukora, R., Tlali, M., Monkwe, S., Charalambous, S., Karat, A. S., Fielding, K. L., … Vassall, A. (2018). Cost of point-of-care lateral flow urine lipoarabinomannan antigen testing in HIV-positive adults in South Africa. The International Journal of Tuberculosis and Lung Disease, 22(9), 1082–1087. https://doi.org/10.5588/ijtld.18.0046

Naidoo, N., Pillay, B., Bubb, M., Pym, A., Chiliza, T., Naidoo, K., … Pillay, M. (2018). Evaluation of a synthetic peptide for the detection of anti- Mycobacterium tuberculosis curli pili IgG antibodies in patients with pulmonary tuberculosis. Tuberculosis, 109, 80–84. https://doi.org/10.1016/j.tube.2018.01.007

Ndung’u, T., Dong, K. L., Kwon, D. S., & Walker, B. D. (2018). A FRESH approach: Combining basic science and social good. Science Immunology, 3(27), eaau2798. https://doi.org/10.1126/sciimmunol.aau2798

Ngwenya, N., Gumede, D., Shahmanesh, M., McGrath, N., Grant, A., & Seeley, J. (2018). Community perceptions of the socio-economic structural context influencing HIV and TB risk, prevention and treatment in a high prevalence area in the era of antiretroviral therapy. African Journal of AIDS Research, 17(1), 72–81. https://doi.org/10.2989/16085906.2017.1415214

Ogunshola, F., Anmole, G., Miller, R. L., Goering, E., Nkosi, T., Muema, D., … Ndhlovu, Z. M. (2018). Dual HLA B*42 and B*81-reactive T cell receptors recognize more diverse HIV-1 Gag escape variants. Nature Communications, 9(1). https://doi.org/10.1038/s41467-018-07209-7

Ojwach, D. B. A., MacMillan, D., Reddy, T., Novitsky, V., Brumme, Z. L., Brockman, M. A., … Mann, J. K. (2018). Pol-driven replicative capacity impacts disease progression in HIV-1 subtype C infection. Journal of Virology, JVI.00811-18. https://doi.org/10.1128/JVI.00811-18

Oldenburg, C. E., Bor, J., Harling, G., Tanser, F., Mutevedzi, T., Shahmanesh, M., … Bärnighausen, T. (2018). Impact of early antiretroviral therapy eligibility on HIV acquisition: Household-level evidence from rural South Africa. AIDS, 1. https://doi.org/10.1097/QAD.0000000000001737

Oldenburg, C. E., Ortblad, K. F., Chanda, M. M., Mwale, M., Chongo, S., Kanchele, C., … Bärnighausen, T. (2018). Intimate Partner Violence and Antiretroviral Therapy Initiation Among Female Sex Workers Newly Diagnosed with HIV in Zambia: A Prospective Study. JAIDS Journal of Acquired Immune Deficiency Syndromes, 1. https://www.ncbi.nlm.nih.gov/pubmed/30142141

Oldenburg, C., Chanda, M. M., Ortblad, K. F., Mwale, M., Chongo, S., Kamungoma, N., … Bärnighausen, T. (2018). Effect of HIV self-testing on the number of sexual partners among female sex workers in Zambia: A randomized controlled trial. AIDS, 1. https://doi.org/10.1097/QAD.0000000000001740

Ortblad, K. F., Bärnighausen, T., Chimbindi, N., Masters, S. H., Salomon, J. A., & Harling, G. (2018). Predictors of male circumcision incidence in a traditionally non-circumcising South African population-based cohort. PLOS ONE, 13(12), e0209172. https://doi.org/10.1371/journal.pone.0209172

Ortblad, K. F., Chanda, M. M., Musoke, D. K., Ngabirano, T., Mwale, M., Nakitende, A., … Oldenburg, C. E. (2018). Acceptability of HIV self-testing to support pre-exposure prophylaxis among female sex workers in Uganda and Zambia: results from two randomized controlled trials. BMC Infectious Diseases, 18(1). https://doi.org/10.1186/s12879-018-3415-z

Pacl, H. T., Reddy, V. P., Saini, V., Chinta, K. C., & Steyn, A. J. (2018). Host-pathogen redox dynamics modulate Mycobacterium tuberculosis pathogenesis. Pathogens and Disease. https://doi.org/10.1093/femspd/fty036

Patten, G., Schomaker, M., Davies, M.-A., Rabie, H., van Zyl, G., Technau, K., … Fairlie, L. (2018). What Should we do When HIV-Positive Children Fail First-Line Combination Antiretroviral Therapy? A Comparison of 4 ART Management Strategies: The Pediatric Infectious Disease Journal, 1. https://doi.org/10.1097/INF.0000000000002156

Perriat, D., Balzer, L., Hayes, R., Lockman, S., Walsh, F., Ayles, H., … the Universal Test and Treat Trials Consortium (UT3C). (2018). Comparative assessment of five trials of universal HIV testing and treatment in sub-Saharan Africa. Journal of the International AIDS Society, 21(1), e25048. https://doi.org/10.1002/jia2.25048

Perriat, D., Plazy, M., Gumede, D., Boyer, S., Pillay, D., Dabis, F., Seeley,J., Orne-Gliemann, J.; ANRS 12249 TasP Study Group.… for the ANRS 12249 TasP Study Group. (2018). “If you are here at the clinic, you do not know how many people need help in the community”: Perspectives of home-based HIV services from health care workers in rural KwaZulu-Natal, South Africa in the era of universal test-and-treat. PLOS ONE, 13(11), e0202473. https://doi.org/10.1371/journal.pone.0202473

Phillips, A. N., Venter, F., Havlir, D., Pozniak, A., Kuritzkes, D., Wensing, A., … Calmy, A. (2018). Risks and benefits of dolutegravir-based antiretroviral drug regimens in sub-Saharan Africa: a modelling study. The Lancet HIV, 6(2), e116–e127. https://doi.org/10.1016/S2352-3018(18)30317-5

Pillay, K., Gardner, M., Gould, A., Otiti, S., Mullineux, J., Bärnighausen, T., & Matthews, P. M. (2018). Long term effect of primary health care training on HIV testing: A quasi-experimental evaluation of the Sexual Health in Practice (SHIP) intervention. PLOS ONE, 13(8), e0199891. https://doi.org/10.1371/journal.pone.0199891

Poole, D. N., Hedt-Gauthier, B., Liao, S., Raymond, N. A., & Bärnighausen, T. (2018). Major depressive disorder prevalence and risk factors among Syrian asylum seekers in Greece. BMC Public Health, 18(1). https://doi.org/10.1186/s12889-018-5822-x

Ramsuran, V., Naranbhai, V., Horowitz, A., Qi, Y., Martin, M. P., Yuki, Y., … Carrington, M. (2018). Elevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells. Science, 359(6371), 86–90. https://doi.org/10.1126/science.aam8825

Ray, P. C., Bayliss, T., Prosser, G. A., Harrison, J. R., Green, K., Soares de Melo, C., … Boshoff, H. I. M. (2018). 2-Mercapto-quinazolinones as inhibitors of NDH-2 and Mycobacterium tuberculosis: Structure-activity relationships, mechanism of action and ADME characterization. ACS Infectious Diseases. https://doi.org/10.1021/acsinfecdis.7b00275

Reddy, V. P., Chinta, K. C., Saini, V., Glasgow, J. N., Hull, T. D., Traylor, A., … Steyn, A. J. C. (2018). Ferritin H Deficiency in Myeloid Compartments Dysregulates Host Energy Metabolism and Increases Susceptibility to Mycobacterium tuberculosis Infection. Frontiers in Immunology, 9. https://doi.org/10.3389/fimmu.2018.00860

Rickman, H. M., Miller, R. F., Morris-Jones, S., Kellgren, L., Edwards, S. G., & Grant, A. D. (2018). Missed opportunities for tuberculosis prevention among patients accessing a UK HIV service. International Journal of STD & AIDS, 095646241877301. https://doi.org/10.1177/0956462418773010

Roider, J., Maehara, T., Ngoepe, A., Ramsuran, D., Muenchhoff, M., Adland, E., … Leslie, A. (2018). High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults. Frontiers in Immunology, 9. https://doi.org/10.3389/fimmu.2018.01975

Rosenberg, M. S., Gómez-Olivé, F. X., Rohr, J. K., Kahn, K., & Bärnighausen, T. W. (2018). Are circumcised men safer sex partners? Findings from the HAALSI cohort in rural South Africa. PLOS ONE, 13(8), e0201445. https://doi.org/10.1371/journal.pone.0201445

Seipone, I. D., Singh, R., Patel, V. B., Singh, A., Gordon, M. L., Muema, D. M., … Ndung’u, T. (2018). Tuberculous meningitis is associated with higher cerebrospinal HIV-1 viral loads compared to other HIV-1-associated meningitides. PLOS ONE, 13(2), e0192060. https://doi.org/10.1371/journal.pone.0192060

Sié, A., Porco, T. C., Dah, C., Lietman, T. M., Keenan, J. D., Ouermi, L., … Snyder, B. M. (2018). Effect of Antibiotics on Short-Term Growth among Children in Burkina Faso: A Randomized Trial. The American Journal of Tropical Medicine and Hygiene. https://doi.org/10.4269/ajtmh.18-0342

Siedner, M. J., & Triant, V. (2018). Undetectable = Untransmittable and Your Health: The personal benefits of early and continuous therapy for HIV infection. The Journal of Infectious Diseases. https://doi.org/10.1093/infdis/jiy445

Siedner, M. J., Baisley, K., Orne-Gliemann, J., Pillay, D., Koole, O., Wong, E. B., … Bachmann, M. (2018). Linkage to primary care after home-based blood pressure screening in rural KwaZulu-Natal, South Africa: a population-based cohort study. BMJ Open, 8(12), e023369. https://doi.org/10.1136/bmjopen-2018-023369

Smith, C. M., Lessells, R., Grant, A. D., Herbst, K., & Tanser, F. (2018). Spatial clustering of drug-resistant tuberculosis in Hlabisa subdistrict, KwaZulu-Natal, 2011–2015. The International Journal of Tuberculosis and Lung Disease, 22(3), 287–293. https://doi.org/10.5588/ijtld.17.0457

Sweeney, S., Mukora, R., Candfield, S., Guinness, L., Grant, A. D., & Vassall, A. (2018). Measuring income for catastrophic cost estimates: Limitations and policy implications of current approaches. Social Science & Medicine, 215, 7–15. https://doi.org/10.1016/j.socscimed.2018.08.041

Tanser, F., Azongo, D. K., Vandormael, A., Bärnighausen, T., & Appleton, C. (2018). Impact of the scale-up of piped water on urogenital schistosomiasis infection in rural South Africa. ELife, 7, e33065. https://doi.org/10.7554/eLife.33065

Tlou, B., Sartorius, B., & Tanser, F. (2018). Investigating risk factors for under-five mortality in an HIV hyper-endemic area of rural South Africa, from 2000-2014. PLOS ONE, 13(11), e0207294. https://doi.org/10.1371/journal.pone.0207294

Tlou, B., Sartorius, B., Tanser, F., 2018. Effect of timing of mother’s death on child survival in a rural HIV hyper-endemic South African population. BMC Public Health,18. https://doi.org/10.1186/s12889-018-6152-8

van der Heijden, Y. F., Karim, F., Chinappa, T., Mufamadi, G., Zako, L., Shepherd, B. E., … Pym, A. S. (2018). Older age at first tuberculosis diagnosis is associated with tuberculosis recurrence in HIV-negative persons. The International Journal of Tuberculosis and Lung Disease, 22(8), 871–877. https://doi.org/10.5588/ijtld.17.0766

Walker-Sperling, V., Ramsuran, V., Martin, M., Naranbhai, V., Li, H., Anderson, S. K., … Carrington, M. (2018). P069UTR SNPS rs111686073 and rs73410010 independently modify expression of tapasin in blacks. Human Immunology, 79, 113. https://doi.org/10.1016/j.humimm.2018.07.128

Wang, Z., Cumming, B. M., Mao, C., Zhu, Y., Lu, P., Steyn, A. J. C., … Hu, Y. (2018). RbpA and σ ^B association regulates polyphosphate levels to modulate mycobacterial isoniazid-tolerance: RbpA and σ ^B associate to regulate INH-tolerance. Molecular Microbiology. https://doi.org/10.1111/mmi.13952

Yoo, H., Lee, J., Yim, J.-J., Bärnighausen, T., Tanser, F., & Park, S. K. (2018). Effect of the Number of Pregnancies on Mortality Risk in HIV-Infected Women: a Prospective Cohort Study in Rural KwaZulu-Natal, South Africa. AIDS and Behavior. https://doi.org/10.1007/s10461-018-2232-0

Yoon, H. A., Nakouzi, A., Chang, C. C., Kuniholm, M. H., Carreño, L. J., Wang, T., … Pirofski, L. (2018). Association between plasma antibody responses and risk for Cryptococcus-associated immune reconstitution inflammatory syndrome. The Journal of Infectious Diseases. https://doi.org/10.1093/infdis/jiy447

2017 Publications

Aicken, C. R. H., Sutcliffe, L. J., Gibbs, J., Tickle, L. J., Hone, K., Harding-Esch, E. M., … Shahmanesh, M. (2017). Using the eSexual Health Clinic to access chlamydia treatment and care via the internet: a qualitative interview study. Sexually Transmitted Infections. https://doi.org/10.1136/sextrans-2017-053227

Akilimali, N. A., Chang, C. C., Muema, D. M., Reddy, T., Moosa, M.-Y. S., Lewin, S. R., … Ndung’u, T. (2017). Plasma But Not Cerebrospinal Fluid Interleukin 7 and Interleukin 5 Levels Pre–Antiretroviral Therapy Commencement Predict Cryptococcosis-Associated Immune Reconstitution Inflammatory Syndrome. Clinical Infectious Diseases, 65(9), 1551–1559. https://doi.org/10.1093/cid/cix598

Akullian, A., Bershteyn, A., Klein, D., Vandormael, A., Bärnighausen, T., & Tanser, F. (2017). Sexual partnership age pairings and risk of HIV acquisition in rural South Africa: AIDS, 31(12), 1755–1764. https://doi.org/10.1097/QAD.0000000000001553

Ambia, J., Renju, J., Wringe, A., Todd, J., Geubbels, E., Nakiyingi-Miiro, J., … Mee, P. (2017). From policy to practice: Exploring the implementation of antiretroviral therapy access and retention policies between 2013 and 2016 in six sub-Saharan African countries. Bmc Health Services Research, 17, 758. https://doi.org/10.1186/s12913-017-2678-1

Baernighausen, T., Oldenburg, C., Tugwell, P., Bommer, C., Ebert, C., Barreto, M., … Vollmer, S. (2017). Quasi-experimental study designs series-paper 7: Assessing the assumptions. Journal of Clinical Epidemiology, 89, 53–66. https://doi.org/10.1016/j.jclinepi.2017.02.017

Baernighausen, T., Rottingen, J.-A., Rockers, P., Shemilt, I., & Tugwell, P. (2017). Quasi-experimental study designs series-paper 1: Introduction: Two historical lineages. Journal of Clinical Epidemiology, 89, 4–11. https://doi.org/10.1016/j.jclinepi.2017.02.020

Baernighausen, T., Tugwell, P., Rottingen, J.-A., Shemilt, I., Rockers, P., Geldsetzer, P., … Atun, R. (2017). Quasi-experimental study designs series-paper 4: Uses and value. Journal of Clinical Epidemiology, 89, 21–29. https://doi.org/10.1016/j.jclinepi.2017.03.012

Baijnath, S., Moodley, C., Ngcobo, B., Singh, S. D., Kruger, H. G., Arvidsson, P. I., … Govender, T. (2017). Clofazimine protects against mycobacterium tuberculosis dissemination in the CNS following an aerosol challenge in a murine model. International Journal of Antimicrobial Agents. https://doi.org/10.1016/j.ijantimicag.2017.08.020

Bernays, S., Bukenya, D., Thompson, C., Ssembajja, F., & Seeley, J. (2017). Being an ‘adolescent’: The consequences of gendered risks for young people in rural Uganda. Childhood, 0907568217732119. https://doi.org/10.1177/0907568217732119

Bhattacharya, D., Danaviah, S., Muema, D. M., Akilimali, N. A., Moodley, P., Ndung’u, T., & Das, G. (2017). Cellular Architecture of Spinal Granulomas and the Immunological Response in Tuberculosis Patients Coinfected with HIV. Frontiers in Immunology, 8, 1120. https://doi.org/10.3389/fimmu.2017.01120

Bocquier, P., Ginsburg, C., Herbst, K., Sankoh, O., & Collinson, M. A. (2017). A training manual for event history data management using Health and Demographic Surveillance System data. BMC Research Notes, 10(1), 224–224. https://doi.org/10.1186/s13104-017-2541-9

Bohlius, J. (2017). Comparison of Kaposi sarcoma risk in HIV-positive adults across five continents: a multiregional multicohort study. Clinical Infectious Diseases. https://doi.org/10.1093/cid/cix480

Bor, J., Ahmed, S., Fox, M. P., Rosen, S., Meyer-Rath, G., Katz, I. T., … Bärnighausen, T. (2017). Effect of eliminating CD4-count thresholds on HIV treatment initiation in South Africa: An empirical modeling study. PLOS ONE, 12(6), e0178249. https://doi.org/10.1371/journal.pone.0178249

Bor, J., Chiu, C., Ahmed, S., Katz, I., Fox, M., Rosen, S., … Bärnighausen, T. (2017). Failure to initiate HIV treatment in patients with high CD4 counts: evidence from demographic surveillance in rural KwaZulu-Natal. Tropical Medicine & International Health, n/a-n/a. https://doi.org/10.1111/tmi.13013

Bor, J., Fox, M. P., Rosen, S., Venkataramani, A., Tanser, F., Pillay, D., & Bärnighausen, T. (2017). Treatment eligibility and retention in clinical HIV care: A regression discontinuity study in South Africa. PLOS Medicine, 14(11), e1002463. https://doi.org/10.1371/journal.pmed.1002463

Brennan, A. T., Davies, M.-A., Bor, J., Wandeler, G., Stinson, K., Wood, R., … Fox, M. P. (2017). Has the phasing out of stavudine in accordance with changes in WHO guidelines led to a decrease in single-drug substitutions in first-line antiretroviral therapy for HIV in sub-Saharan Africa? AIDS, 31(1). Retrieved from http://journals.lww.com/aidsonline/Fulltext/2017/01020/Has_the_phasing_out_of_stavudine_in_accordance.16.aspx

Bärnighausen, T. (2017). Population health intervention research: three important advancements. International Journal of Public Health. https://doi.org/10.1007/s00038-017-0985-2

Bukenya, D., Wringe, A., Moshabela, M., Skovdal, M., Ssekubugu, R., Paparini, S., … Seeley, J. (2017). Where are we now? A multicountry qualitative study to explore access to pre-antiretroviral care services: a precursor to antiretroviral therapy initiation. Sexually Transmitted Infections, 93(Suppl 3). https://doi.org/10.1136/sextrans-2016-052970

Chanda, M. M., Ortblad, K. F., Mwale, M., Chongo, S., Kanchele, C., Kamungoma, N., … Oldenburg, C. E. (2017). HIV self-testing among female sex workers in Zambia: A cluster randomized controlled trial. PLOS Medicine, 14(11), e1002442. https://doi.org/10.1371/journal.pmed.1002442

Chanda, M. M., Ortblad, K. F., Mwale, M., Chongo, S., Kanchele, C., Kamungoma, N., … Oldenburg, C. E. (2017). Contraceptive use and unplanned pregnancy among female sex workers in Zambia. Contraception, 96(3), 196–202. https://doi.org/10.1016/j.contraception.2017.07.003

Chang, C. C., Kangethe, R., Omarjee, S., Hiramen, K., Gosnell, B., Sojane, K., … Ndung’u, T. (2017). Relationship of Human Immunodeficiency Virus Viral Load in Cerebrospinal Fluid and Plasma in Patients Co-infected With Cryptococcal Meningitis. Open Forum Infectious Diseases, 4(2). https://doi.org/10.1093/ofid/ofx032

Collier, D., Iwuji, C., Derache, A., de Oliveira, T., Okesola, N., Calmy, A., … Gupta, R. K. (2017). Virological Outcomes of Second-line Protease Inhibitor–Based Treatment for Human Immunodeficiency Virus Type 1 in a High-Prevalence Rural South African Setting: A Competing-Risks Prospective Cohort Analysis. Clinical Infectious Diseases, 64(8), 1006–1016. https://doi.org/10.1093/cid/cix015

Cordes, J. L., Stangl, A., Krishnaratne, S., Hoddinott, G., Mathema, H., Bond, V., … Hargreaves, J. R. (2017). Trends in Responses to DHS Questions Should Not Be Interpreted as Reflecting an Increase in “Anticipated Stigma” in Africa: JAIDS Journal of Acquired Immune Deficiency Syndromes, 75(1), e22–e23. https://doi.org/10.1097/QAI.0000000000001328

Cornell, M., Johnson, L. F., Wood, R., Tanser, F., Fox, M. P., Prozesky, H., … Boulle, A. (2017). Twelve-year mortality in adults initiating antiretroviral therapy in South Africa. Journal of the International AIDS Society, 20(1). https://doi.org/10.7448/IAS.20.1.21902

Cox, H., Dickson-Hall, L., Ndjeka, N., van’t Hoog, A., Grant, A., Cobelens, F., … Nicol, M. (2017). Delays and loss to follow-up before treatment of drug-resistant tuberculosis following implementation of Xpert MTB/RIF in South Africa: A retrospective cohort study. PLOS Medicine, 14(2), e1002238. https://doi.org/10.1371/journal.pmed.1002238

Cuadros, D. F., Li, J., Branscum, A. J., Akullian, A., Jia, P., Mziray, E. N., & Tanser, F. (2017). Mapping the spatial variability of HIV infection in Sub-Saharan Africa: Effective information for localized HIV prevention and control. Scientific Reports, 7(1), 9093. https://doi.org/10.1038/s41598-017-09464-y

Cumming, B. M., Chinta, K. C., Reddy, V. P., & Steyn, A. J. C. (2017). Role of Ergothioneine in Microbial Physiology and Pathogenesis. Antioxidants & Redox Signaling. https://doi.org/10.1089/ars.2017.7300

Cumming, B. M., Rahman, M. A., Lamprecht, D. A., Rohde, K. H., Saini, V., Adamson, J. H., … Steyn, A. J. C. (2017). Mycobacterium tuberculosis arrests host cycle at the G1/S transition to establish long term infection. PLOS Pathogens, 13(5), e1006389. https://doi.org/10.1371/journal.ppat.1006389

De Neve, J.-W., & Harling, G. (2017). Offspring schooling associated with increased parental survival in rural KwaZulu-Natal, South Africa. Social Science & Medicine, 176, 149–157. https://doi.org/10.1016/j.socscimed.2017.01.015

de Welzen, L., Eldholm, V., Maharaj, K., Manson, A. L., Earl, A. M., & Pym, A. S. (2017). Whole transcriptome and genomic analysis of extensively drug-resistant Mycobacterium tuberculosis clinical isolates identifies downregulation of ethA as a mechanism of ethionamide resistance. Antimicrobial Agents and Chemotherapy. https://doi.org/10.1128/AAC.01461-17

Dobra, A., Bärnighausen, T., Vandormael, A., & Tanser, F. (2017). Space-time migration patterns and risk of HIV acquisition in rural South Africa. AIDS (London, England), 31(1), 137–145. https://doi.org/10.1097/QAD.0000000000001292

Dong, K. L., Moodley, A., Kwon, D. S., Ghebremichael, M. S., Dong, M., Ismail, N., … Ndung’u, T. (n.d.). Detection and treatment of Fiebig stage I HIV-1 infection in young at-risk women in South Africa: a prospective cohort study. The Lancet HIV. https://doi.org/10.1016/S2352-3018(17)30146-7

Dowdy, D. W., Grant, A. D., Dheda, K., Nardell, E., Fielding, K., & Moore, D. A. J. (2017). Designing and Evaluating Interventions to Halt the Transmission of Tuberculosis. The Journal of Infectious Diseases, 216(suppl_6), S654–S661. https://doi.org/10.1093/infdis/jix320

Gatuguta, A., Katusiime, B., Seeley, J., Colombini, M., Mwanzo, I., & Devries, K. (2017). Should community health workers offer support healthcare services to survivors of sexual violence? a systematic review. BMC International Health and Human Rights, 17(1), 28. https://doi.org/10.1186/s12914-017-0137-z

Geldsetzer, P., De Neve, J.-W., Boudreaux, C., Bärnighausen, T., & Bossert, T. J. (2017). Improving the performance of community health workers in Swaziland: findings from a qualitative study. Human Resources for Health, 15(1), 68. https://doi.org/10.1186/s12960-017-0236-x

Geldsetzer, P., Feigl, A. B., Tanser, F., Gareta, D., Pillay, D., & Bärnighausen, T. (2017). Population-level decline in BMI and systolic blood pressure following mass HIV treatment: Evidence from rural KwaZulu-Natal: Decline in BMI and BP following Mass HIV Treatment. Obesity, 25(1), 200–206. https://doi.org/10.1002/oby.21663

Godfrey, C., Thigpen, M. C., Crawford, K. W., Jean-Phillippe, P., Pillay, D., Persaud, D., … Fitzgibbon, J. (2017). Global HIV Antiretroviral Drug Resistance. The Journal of Infectious Diseases. https://doi.org/10.1093/infdis/jix137

Goodall, R. L., Dunn, D. T., Nkurunziza, P., Mugarura, L., Pattery, T., Munderi, P., … Gupta, R. K. (2017). Rapid accumulation of HIV-1 thymidine analogue mutations and phenotypic impact following prolonged viral failure on zidovudine-based first-line ART in sub-Saharan Africa. Journal of Antimicrobial Chemotherapy, 72(5), 1450–1455. https://doi.org/10.1093/jac/dkw583

Gupta, R. K., Gregson, J., Parkin, N., Haile-Selassie, H., Tanuri, A., Andrade Forero, L., … Bertagnolio, S. (2017). HIV-1 drug resistance before initiation or re-initiation of first-line antiretroviral therapy in low-income and middle-income countries: a systematic review and meta-regression analysis. The Lancet Infectious Diseases. https://doi.org/10.1016/S1473-3099(17)30702-8

Haber, N., Tanser, F., Bor, J., Naidu, K., Mutevedzi, T., Herbst, K., … Bärnighausen, T. (2017). From HIV infection to therapeutic response: a population-based longitudinal HIV cascade-of-care study in KwaZulu-Natal, South Africa. The Lancet HIV, 4(5), e223–e230. https://doi.org/10.1016/S2352-3018(16)30224-7

Hainsworth, E. G., Shahmanesh, M., & Stevenson, F. (2017). Exploring the views and experiences of HIV positive patients treated for cancer: a systematic review of the literature. AIDS Care, 1–9. https://doi.org/10.1080/09540121.2017.1381332

Hanifa, Y., Fielding, K. L., Chihota, V. N., Adonis, L., Charalambous, S., Foster, N., … Grant, A. D. (2017). A clinical scoring system to prioritise investigation for tuberculosis among adults attending HIV clinics in South Africa. PLOS ONE, 12(8), e0181519. https://doi.org/10.1371/journal.pone.0181519

Harling, G., Gumede, D., Mutevedzi, T., McGrath, N., Seeley, J., Pillay, D., … Herbst, A. J. (2017). The impact of self-interviews on response patterns for sensitive topics: a randomized trial of electronic delivery methods for a sexual behaviour questionnaire in rural South Africa. BMC Medical Research Methodology, 17(1), 125. https://doi.org/10.1186/s12874-017-0403-8

Harling, G., McGrath, N., Seeley, J., BBrnighausen, T. W., & Herbst, A. J. (2017). The Advantages and Disadvantages of Self-Interviews for Sensitive Topics: A Randomized Trial of Electronic Delivery Methods for a Sexual Behaviour Questionnaire in Rural South Africa. SSRN Electronic Journal. https://doi.org/10.2139/ssrn.2945424

Helova, A., Akama, E., Bukusi, E. A., Musoke, P., Nalwa, W. Z., Odeny, T. A., … Abuogi, L. L. (2017). Health facility challenges to the provision of Option B+ in western Kenya: a qualitative study. Health Policy Plan, 32.

Iwuji, C. C., Orne-Gliemann, J., Larmarange, J., Balestre, E., Thiebaut, R., Tanser, F., … Rekacewicz, C. (2017). Universal test and treat and the HIV epidemic in rural South Africa: a phase 4, open-label, community cluster randomised trial. The Lancet HIV. https://doi.org/10.1016/S2352-3018(17)30205-9

Iwuji, C., & Newell, M.-L. (2017a). HIV testing: The “front door” to the UNAIDS 90-90-90 target. Public Health Action, 7(2), 79–79. https://doi.org/10.5588/ijtld.17.0046

Iwuji, C., & Newell, M.-L. (2017b). Towards control of the global HIV epidemic: Addressing the middle-90 challenge in the UNAIDS 90-90-90 target. Plos Medicine, 14(5), e1002293. https://doi.org/10.1371/journal.pmed.1002293

Jackson, L., Hunter, J., Cele, S., Ferreira, I. M., Young, A., Karim, F., … Sigal, A. (2017). Incomplete inhibition of HIV infection results in more HIV infected lymph node cells by reducing cell death. https://doi.org/10.1101/163352

Jardim, T. V., Reiger, S., Abrahams-Gessel, S., Gomez-Olive, F. X., Wagner, R. G., Wade, A., … Gaziano, T. A. (2017). Hypertension management in a population of older adults in rural South Africa: Journal of Hypertension, 35(6), 1283–1289. https://doi.org/10.1097/HJH.0000000000001312

Karat, A. S., Tlali, M., Fielding, K. L., Charalambous, S., Chihota, V. N., Churchyard, G. J., … Grant, A. D. (2017). Measuring mortality due to HIV-associated tuberculosis among adults in South Africa: Comparing verbal autopsy, minimally-invasive autopsy, and research data. PLOS ONE, 12(3), e0174097. https://doi.org/10.1371/journal.pone.0174097

Kaufmann, S. H. E., Dockrell, H. M., Drager, N., Ho, M. M., McShane, H., Neyrolles, O., … Hogarth, P. (2017). TBVAC2020: Advancing Tuberculosis Vaccines from Discovery to Clinical Development. Frontiers in Immunology, 8, 1203. https://doi.org/10.3389/fimmu.2017.01203

Kiguoya, M. W., Mann, J. K., Chopera, D., Gounder, K., Lee, G. Q., Hunt, P. W., … Ndung’u, T. (2017). Subtype-Specific Differences in Gag-Protease-Driven Replication Capacity Are Consistent with Intersubtype Differences in HIV-1 Disease Progression. Journal of Virology, 91(13), e00253-17. https://doi.org/10.1128/JVI.00253-17

Kiwuwa-Muyingo, S., Nazziwa, J., Ssemwanga, D., Ilmonen, P., Njai, H., Ndembi, N., … Kaleebu, P. (2017). HIV-1 transmission networks in high risk fishing communities on the shores of Lake Victoria in Uganda: A phylogenetic and epidemiological approach. PLOS ONE, 12(10), e0185818. https://doi.org/10.1371/journal.pone.0185818

Kugathasan, R., Collier, D. A., Haddow, L. J., El Bouzidi, K., Edwards, S. G., Cartledge, J. D., … Gupta, R. K. (2017). Diffuse White Matter Signal Abnormalities on Magnetic Resonance Imaging Are Associated With Human Immunodeficiency Virus Type 1 Viral Escape in the Central Nervous System Among Patients With Neurological Symptoms. Clinical Infectious Diseases, 64(8), 1059–1065. https://doi.org/10.1093/cid/cix035

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Yates, T. A., Khan, P. Y., Knight, G. M., Taylor, J. G., McHugh, T. D., Lipman, M., … Abubakar, I. (n.d.). The transmission of Mycobacterium tuberculosis in high burden settings. The Lancet Infectious Diseases, 16(2), 227–238. https://doi.org/10.1016/S1473-3099(15)00499-5

Zhou, B., Bentham, J., Di Cesare, M., Bixby, H., Danaei, G., Cowan, M. J., … Zuñiga Cisneros, J. (n.d.). Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants. The Lancet, 389(10064), 37–55. https://doi.org/10.1016/S0140-6736(16)31919-5

Zhukova, A., Cutino-Moguel, T., Gascuel, O., & Pillay, D. (2017). The Role of Phylogenetics as a Tool to Predict the Spread of Resistance. The Journal of Infectious Diseases, jix411-jix411. https://doi.org/10.1093/infdis/jix411

Zulu, M., Naidoo, K., Mncube, Z., Jaggernath, M., Goulder, P. J., Ndung’u, T., … Thobakgale, C. F. (2017). Reduced Expression of Siglec-7, NKG2A and CD57 on Terminally Differentiated CD56-CD16+ NK Cell Subset is associated with NK Cell Dysfunction in Chronic HIV-1 clade C Infection. AIDS Research and Human Retroviruses. https://doi.org/10.1089/AID.2017.0095

Zuma, T., Wight, D., Rochat, T., & Moshabela, M. (2017). Traditional health practitioners’ management of HIV/AIDS in rural South Africa in the era of widespread antiretroviral therapy. Global Health Action, 10(1), 1352210. https://doi.org/10.1080/16549716.2017.1352210

2016 Publications

Aicken, C. R. H., Fuller, S. S., Sutcliffe, L. J., Estcourt, C. S., Gkatzidou, V., Oakeshott, P., … Shahmanesh, M. (2016). Young people’s perceptions of smartphone-enabled self-testing and online care for sexually transmitted infections: qualitative interview study. BMC Public Health, 16(1), 974. https://doi.org/10.1186/s12889-016-3648-y

Atun, R., Chang, A. Y., Ogbuoji, O., Silva, S., Resch, S., Hontelez, J., & Bärnighausen, T. (2016). Long-term financing needs for HIV control in sub-Saharan Africa in 2015–2050: a modelling study. BMJ Open, 6(3). https://doi.org/10.1136/bmjopen-2015-009656

Barnhart, D., Hertzmark, E., Liu, E., Mungure, E., Muya, A. N., Sando, D., … Spiegelman, D. (2016). Intra-cluster correlation estimates for HIV-related outcomes from care and treatment clinics in Dar es Salaam, Tanzania. Contemporary Clinical Trials Communications, 4, 161–169. https://doi.org/10.1016/j.conctc.2016.09.001

BCCP: Botswana Combination Prevention Project. clinicaltrials.gov. 2015. https://clinicaltrials.gov/ct2/show/NCT01965470. Accessed 1 Sept 2016. (n.d.). Retrieved from https://clinicaltrials.gov/ct2/show/NCT01965470

Bohlius, J., Maxwell, N., Spoerri, A., Wainwright, R., Sawry, S., Poole, J., … for IeDEA-Southern Africa. (2016). Incidence of AIDS-Defining and Other Cancers in HIV-Positive Children in South Africa: Record Linkage Study. The Pediatric Infectious Disease Journal, 35(6), e164–e170. https://doi.org/10.1097/INF.0000000000001117

Boullé, M., Müller, T. G., Dähling, S., Ganga, Y., Jackson, L., Mahamed, D., … Sigal, A. (2016). HIV Cell-to-Cell Spread Results in Earlier Onset of Viral Gene Expression by Multiple Infections per Cell. PLOS Pathogens, 12(11), e1005964. https://doi.org/10.1371/journal.ppat.1005964

Boyer, S., Iwuji, C., Gosset, A., Protopopescu, C., Okesola, N., Plazy, M., … on behalf of the ANRS 12249 TasP study group. (2016). Factors associated with antiretroviral treatment initiation amongst HIV-positive individuals linked to care within a universal test and treat programme: early findings of the ANRS 12249 TasP trial in rural South Africa. AIDS Care, 28(Suppl 3), 39–51. https://doi.org/10.1080/09540121.2016.1164808

Brice, J., Sylla, M., Sayon, S., Telly, F., Bocar-Fofana, D., Murphy, R., … Maiga, A. I. (2016). Qualitative and quantitative HIV antibodies and viral reservoir size characterization in vertically infected children with virological suppression. Journal of Antimicrobial Chemotherapy, dkw537. https://doi.org/10.1093/jac/dkw537

Bärnighausen, T., Bloom, D. E., & Humair, S. (2016). Human Resources for Treating HIV/AIDS: Are the Preventive Effects of Antiretroviral Treatment a Game Changer? PLOS ONE, 11(10), e0163960. https://doi.org/10.1371/journal.pone.0163960

Byrne, E. H., Anahtar, M. N., Cohen, K. E., Moodley, A., Padavattan, N., Ismail, N., … Kwon, D. S. (2016). Association between injectable progestin-only contraceptives and HIV acquisition and HIV target cell frequency in the female genital tract in South African women: a prospective cohort study. The Lancet Infectious Diseases, 16(4), 441–448. https://doi.org/10.1016/S1473-3099(15)00429-6

Carlson, J. M., Du, V. Y., Pfeifer, N., Bansal, A., Tan, V. Y. F., Power, K., … Goepfert, P. A. (2016). Impact of pre-adapted HIV transmission. Nature Medicine, 22(6), 606–613. https://doi.org/10.1038/nm.4100

Channon, M., Hosegood, V., & McGrath, N. (2016). A longitudinal population-based analysis of relationship status and mortality in KwaZulu-Natal, South Africa 2001–2011. Journal of Epidemiology and Community Health, 70(1), 56–64. https://doi.org/10.1136/jech-2014-205408

Chen, Z., Hu, Y., Cumming, B. M., Lu, P., Feng, L., Deng, J., … Chen, S. (n.d.). Mycobacterial WhiB6 Differentially Regulates ESX-1 and the Dos Regulon to Modulate Granuloma Formation and Virulence in Zebrafish. Cell Reports, 16(9), 2512–2524. https://doi.org/10.1016/j.celrep.2016.07.080

Chetty, T., Thorne, C., Tanser, F., Bärnighausen, T., & Coutsoudis, A. (2016). Cohort profile: the Hlabisa pregnancy cohort, KwaZulu-Natal, South Africa. BMJ Open, 6(10), e012088. https://doi.org/10.1136/bmjopen-2016-012088

Chikovore, J., Gillespie, N., McGrath, N., Orne-Gliemann, J., Zuma, T., & On Behalf of the ANRS 12249 TasP Study Group. (2016). Men, masculinity, and engagement with treatment as prevention in KwaZulu-Natal, South Africa. AIDS Care, 28(sup3), 74–82. https://doi.org/10.1080/09540121.2016.1178953

Chinta, K. C., Saini, V., Glasgow, J. N., Mazorodze, J. H., Rahman, M. A., Reddy, D., … Steyn, A. J. C. (2016). The emerging role of gasotransmitters in the pathogenesis of tuberculosis. Nitric Oxide, 59, 28–41. https://doi.org/10.1016/j.niox.2016.06.009

Cohen, K. A., El-Hay, T., Wyres, K. L., Weissbrod, O., Munsamy, V., Yanover, C., … Pym, A. S. (n.d.). Paradoxical Hypersusceptibility of Drug-resistant Mycobacteriumtuberculosis to β-lactam Antibiotics. EBioMedicine, 9, 170–179. https://doi.org/10.1016/j.ebiom.2016.05.041

Conroy, A. A., McGrath, N., van Rooyen, H., Hosegood, V., Johnson, M. O., Fritz, K., … Darbes, L. A. (2016). Power and the association with relationship quality in South African couples: Implications for HIV/AIDS interventions. Social Science & Medicine, 153, 1–11. https://doi.org/10.1016/j.socscimed.2016.01.035

Delva, W., Leventhal, G. E., & Helleringer, S. (2016). Connecting the dots: network data and models in HIV epidemiology. AIDS, 30. https://doi.org/10.1097/QAD.0000000000001184

Desjardins, C. A., Cohen, K. A., Munsamy, V., Abeel, T., Maharaj, K., Walker, B. J., … Pym, A. S. (2016). Genomic and functional analyses of Mycobacterium tuberculosis strains implicate ald in D-cycloserine resistance. Nature Genetics, 48(5), 544–551. https://doi.org/10.1038/ng.3548

Dimitrov, D. T., Boily, M.-C., Hallett, T. B., Albert, J., Boucher, C., Mellors, J. W., … van de Vijver, D. A. M. C. (2016). How Much Do We Know about Drug Resistance Due to PrEP Use? Analysis of Experts’ Opinion and Its Influence on the Projected Public Health Impact. PLoS ONE, 11(7), e0158620. https://doi.org/10.1371/journal.pone.0158620

El Bouzidi, K., White, E., Mbisa, J. L., Sabin, C. A., Phillips, A. N., Mackie, N., … Dunn, D. T. (2016). HIV-1 drug resistance mutations emerging on darunavir therapy in PI-naive and -experienced patients in the UK. Journal of Antimicrobial Chemotherapy, 71(12), 3487–3494. https://doi.org/10.1093/jac/dkw343

Evangeli, M., Newell, M.-L., & McGrath, N. (2016). Factors associated with pre-ART loss-to-follow up in adults in rural KwaZulu-Natal, South Africa: a prospective cohort study. BMC Public Health, 16(1), 358. https://doi.org/10.1186/s12889-016-3025-x

Feigl, A. B., Bloom, D. E., Danaei, G., Pillay, D., Salomon, J. A., Tanser, F., & Bärnighausen, T. W. (2016). The Effect of HIV and the Modifying Effect of Anti-Retroviral Therapy (ART) on Body Mass Index (BMI) and Blood Pressure Levels in Rural South Africa. PLOS ONE, 11(8), e0158264. https://doi.org/10.1371/journal.pone.0158264

Ferns, R. B., Tarr, A. W., Hue, S., Urbanowicz, R. A., McClure, C. P., Gilson, R., … Pillay, D. (2016). Hepatitis C virus quasispecies and pseudotype analysis from acute infection to chronicity in HIV-1 co-infected individuals. Virology, 492, 213–224. https://doi.org/10.1016/j.virol.2016.02.003

Fox, M. P., Rosen, S., Geldsetzer, P., Bärnighausen, T., Negussie, E., & Beanland, R. (2016). Interventions to improve the rate or timing of initiation of antiretroviral therapy for HIV in sub-Saharan Africa: meta-analyses of effectiveness. Journal of the International AIDS Society, 19(1). https://doi.org/10.7448/IAS.19.1.20888

Garrett, N. J., McGrath, N., & Mindel, A. (2017). Advancing STI care in low/middle-income countries: has STI syndromic management reached its use-by date? Sexually Transmitted Infections, 93(1), 4. https://doi.org/10.1136/sextrans-2016-052581

Geldsetzer, P., Fink, G., Vaikath, M., & Bärnighausen, T. (2016). Sampling for Patient Exit Interviews: Assessment of Methods Using Mathematical Derivation and Computer Simulations. Health Services Research. https://doi.org/10.1111/1475-6773.12611

Geldsetzer, P., Ortblad, K., & Bärnighausen, T. (2016). The efficiency of chronic disease care in sub-Saharan Africa. BMC Medicine, 14(1). https://doi.org/10.1186/s12916-016-0675-6

Geldsetzer, P., Yapa, H. M. N., Vaikath, M., Ogbuoji, O., Fox, M. P., Essajee, S. M., … Bärnighausen, T. (2016). A systematic review of interventions to improve postpartum retention of women in PMTCT and ART care. Journal of the International AIDS Society, 19(1). https://doi.org/10.7448/IAS.19.1.20679

Ginsburg, C., Bocquier, P., Béguy, D., Afolabi, S., Augusto, O., Derra, K., … Collinson, M. A. (2016). Healthy or unhealthy migrants? Identifying internal migration effects on mortality in Africa using health and demographic surveillance systems of the INDEPTH network. Social Science & Medicine, 164, 59–73. https://doi.org/10.1016/j.socscimed.2016.06.035

Global epidemiology of drug resistance after failure of WHO recommended first-line regimens for adult HIV-1 infection: a multicentre retrospective cohort study. (2016). The Lancet Infectious Diseases, 16(5), 565–575. https://doi.org/10.1016/S1473-3099(15)00536-8

Gosmann, C., Anahtar, M. N., Handley, S. A., Farcasanu, M., Abu-Ali, G., Bowman, B. A., … Kwon, D. S. (n.d.). Lactobacillus-Deficient Cervicovaginal Bacterial Communities Are Associated with Increased HIV Acquisition in Young South African Women. Immunity, 46(1), 29–37. https://doi.org/10.1016/j.immuni.2016.12.013

Gounder, K., Oyaro, M., Padayachi, N., Zulu, T. M., de Oliveira, T., Wylie, J., & Ndung’u, T. (2017). Complex Subtype Diversity of HIV-1 Among Drug Users in Major Kenyan Cities. AIDS Research and Human Retroviruses, 33(5), 500–510. https://doi.org/10.1089/aid.2016.0321

Grimsrud, A., Cornell, M., Schomaker, M., Fox, M. P., Orrell, C., Prozesky, H., … Myer, L. (2016). CD4 count at antiretroviral therapy initiation and the risk of loss to follow-up: results from a multicentre cohort study. Journal of Epidemiology and Community Health, 70(6), 549–555. https://doi.org/10.1136/jech-2015-206629

Haber, N., Pillay, D., Porter, K., & Bärnighausen, T. (2016). Constructing the cascade of HIV care: methods for measurement. Current Opinion in HIV and AIDS, 11(1), 102–108. https://doi.org/10.1097/COH.0000000000000212

Harling, G., & Bärnighausen, T. (2016). The role of partners’ educational attainment in the association between HIV and education amongst women in seven sub-Saharan African countries. Journal of the International AIDS Society, 19(1). https://doi.org/10.7448/IAS.19.1.20038

Heidebrecht, C. L., Podewils, L. J., Pym, A. S., Cohen, T., Mthiyane, T., & Wilson, D. (2016). Assessing the utility of Xpert® MTB/RIF as a screening tool for patients admitted to medical wards in South Africa, 6, 19391.

Heidebrecht, C. L., Podewils, L. J., Pym, A., Mthiyane, T., & Cohen, T. (2016). Assessing Local Risk of Rifampicin-Resistant Tuberculosis in KwaZulu-Natal, South Africa Using Lot Quality Assurance Sampling. PLOS ONE, 11(4), e0153143. https://doi.org/10.1371/journal.pone.0153143

Hennig, S., Naiker, S., Reddy, T., Egan, D., Kellerman, T., Wiesner, L., … Pym, A. (2016). Effect of SLCO1B1 Polymorphisms on Rifabutin Pharmacokinetics in African HIV-Infected Patients with Tuberculosis. Antimicrobial Agents and Chemotherapy, 60(1), 617–620. https://doi.org/10.1128/AAC.01195-15

Hennig, S., Svensson, E. M., Niebecker, R., Fourie, P. B., Weiner, M. H., Bonora, S., … Karlsson, M. O. (2016). Population pharmacokinetic drug–drug interaction pooled analysis of existing data for rifabutin and HIV PIs. Journal of Antimicrobial Chemotherapy, 71(5), 1330–1340. https://doi.org/10.1093/jac/dkv470

Herbeck, J., & Tanser, F. (2016). Community viral load as an index of HIV transmission potential. The Lancet HIV, 3(4), e152–e154. https://doi.org/10.1016/S2352-3018(16)00036-9

Hontelez, J. A. C., Tanser, F. C., Naidu, K. K., Pillay, D., & Bärnighausen, T. (2016). The Effect of Antiretroviral Treatment on Health Care Utilization in Rural South Africa: A Population-Based Cohort Study. PLOS ONE, 11(7), e0158015. https://doi.org/10.1371/journal.pone.0158015

Iwuji C, Orne-Gliemann J, Balestre E, Larmarange J, Thiebaut R, Tanser F, et al. Abstract: The impact of universal test and treat on HIV incidence in a rural South African population: ANRS 12249 TasP trial, 2012-2016. In: International AIDS Conference 2016, Durban, South Africa. Durban; 2016. http://programme.aids2016.org/Abstract/Abstract/10537 . (n.d.). Retrieved from http://programme.aids2016.org/Abstract/Abstract/10537

Iwuji, C. C., Orne-Gliemann, J., Larmarange, J., Okesola, N., Tanser, F., Thiebaut, R., … ANRS 12249 TasP trial group. (2016). Uptake of Home-Based HIV Testing, Linkage to Care, and Community Attitudes about ART in Rural KwaZulu-Natal, South Africa: Descriptive Results from the First Phase of the ANRS 12249 TasP Cluster-Randomised Trial. PLOS Medicine, 13(8), e1002107. https://doi.org/10.1371/journal.pmed.1002107

Jaggernath, M., Naicker, R., Madurai, S., Brockman, M. A., Ndung’u, T., & Gelderblom, H. C. (2016). Diagnostic Accuracy of the HemoCue Hb 301, STAT-Site MHgb and URIT-12 Point-of-Care Hemoglobin Meters in a Central Laboratory and a Community Based Clinic in Durban, South Africa. PLOS ONE, 11(4), e0152184. https://doi.org/10.1371/journal.pone.0152184

Jain, P., Weinrick, B. C., Kalivoda, E. J., Yang, H., Munsamy, V., Vilcheze, C., … Jacobs, W. R. (2016). Dual-Reporter Mycobacteriophages (Φ ² DRMs) Reveal Preexisting Mycobacterium tuberculosis Persistent Cells in Human Sputum. MBio, 7(5), e01023-16. https://doi.org/10.1128/mBio.01023-16

Johnson, L. F., Keiser, O., Fox, M. P., Tanser, F., Cornell, M., Hoffmann, C. J., … for the International Epidemiologic Databases to Evaluate AIDS Southern Africa (IeDEA-SA) Collaboration. (2016). Life expectancy trends in adults on antiretroviral treatment in South Africa. AIDS, 30(16). Retrieved from http://journals.lww.com/aidsonline/Fulltext/2016/10230/Life_expectancy_trends_in_adults_on_antiretroviral.16.aspx

Kaposi Sarcoma Risk in HIV-Infected Children and Adolescents on Combination Antiretroviral Therapy From Sub-Saharan Africa, Europe, and Asia. (2016). Clinical Infectious Diseases, ciw519. https://doi.org/10.1093/cid/ciw519

Karat, A. S., Omar, T., von Gottberg, A., Tlali, M., Chihota, V. N., Churchyard, G. J., … Grant, A. D. (2016). Autopsy Prevalence of Tuberculosis and Other Potentially Treatable Infections among Adults with Advanced HIV Enrolled in Out-Patient Care in South Africa. PLOS ONE, 11(11), e0166158. https://doi.org/10.1371/journal.pone.0166158

Karnon, J., & Orji, N. (2016). Option B+ for the prevention of mother-to-child transmission of HIV infection in developing countries: a review of published cost-effectiveness analyses. Health Policy Plan, 31. https://doi.org/10.1093/heapol/czw025

Kasprowicz, V. O., Cheng, T.-Y., Ndung’u, T., Sunpath, H., Moody, D. B., & Kasmar, A. G. (2016). HIV Disrupts Human T Cells That Target Mycobacterial Glycolipids. Journal of Infectious Diseases, 213(4), 628–633. https://doi.org/10.1093/infdis/jiv455

Kassebaum, N. J., Arora, M., Barber, R. M., Bhutta, Z. A., Brown, J., Carter, A., … Murray, C. J. L. (2016). Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1603–1658. https://doi.org/10.1016/S0140-6736(16)31460-X

Kassebaum, N. J., Barber, R. M., Bhutta, Z. A., Dandona, L., Gething, P. W., Hay, S. I., … Murray, C. J. L. (2016). Global, regional, and national levels of maternal mortality, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1775–1812. https://doi.org/10.1016/S0140-6736(16)31470-2

Kløverpris, H. N., Kazer, S. W., Mjösberg, J., Mabuka, J. M., Wellmann, A., Ndhlovu, Z., … Leslie, A. (2016). Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression. Immunity, 44(2), 391–405. https://doi.org/10.1016/j.immuni.2016.01.006

Koofhethile, C. K., Ndhlovu, Z. M., Thobakgale-Tshabalala, C., Prado, J. G., Ismail, N., Mncube, Z., … Ndung’u, T. (2016). CD8 ⁺ T Cell Breadth and Ex Vivo Virus Inhibition Capacity Distinguish between Viremic Controllers with and without Protective HLA Class I Alleles. Journal of Virology, 90(15), 6818–6831. https://doi.org/10.1128/JVI.00276-16

Koto, M. V., & Maharaj, P. (2016). Difficulties facing healthcare workers in the era of AIDS treatment in Lesotho. Sahara J, 13. https://doi.org/10.1080/17290376.2016.1179588

Lamprecht, D. A., Finin, P. M., Rahman, M. A., Cumming, B. M., Russell, S. L., Jonnala, S. R., … Steyn, A. J. C. (2016). Turning the respiratory flexibility of Mycobacterium tuberculosis against itself. Nature Communications, 7, 12393. https://doi.org/10.1038/ncomms12393

Leitman, E. M., Hurst, J., Mori, M., Kublin, J., Ndung’u, T., Walker, B. D., … Goulder, P. J. R. (2016). Lower Viral Loads and Slower CD4+ T-Cell Count Decline in MRKAd5 HIV-1 Vaccinees Expressing Disease-Susceptible HLA-B*58:02. The Journal of Infectious Diseases, 214(3), 379–389. https://doi.org/10.1093/infdis/jiw093

Leitman, E. M., Thobakgale, C. F., Adland, E., Ansari, M. A., Raghwani, J., Prendergast, A. J., … Goulder, P. J. R. (2017). Role of HIV-specific CD8⁺ T cells in pediatric HIV cure strategies after widespread early viral escape. The Journal of Experimental Medicine. https://doi.org/10.1084/jem.20162123

Madlala, P., Singh, R., An, P., Werner, L., Mlisana, K., Abdool Karim, S. S., … Ndung’u, T. (2016). Association of Polymorphisms in the Regulatory Region of the Cyclophilin a Gene (PPIA) with Gene Expression and HIV/AIDS Disease Progression. JAIDS Journal of Acquired Immune Deficiency Syndromes, 72(5). Retrieved from http://journals.lww.com/jaids/Fulltext/2016/08150/Association_of_Polymorphisms_in_the_Regulatory.1.aspx

Manasa, J., Danaviah, S., Lessells, R., Elshareef, M., Tanser, F., Wilkinson, E., … for the Southern African Treatment and Resistance Network. (2016). Increasing HIV-1 Drug Resistance Between 2010 and 2012 in Adults Participating in Population-Based HIV Surveillance in Rural KwaZulu-Natal, South Africa. AIDS Research and Human Retroviruses, 32(8), 763–769. https://doi.org/10.1089/aid.2015.0225

Manne-Goehler, J., Atun, R., Stokes, A., Goehler, A., Houinato, D., Houehanou, C., … Bärnighausen, T. (2016). Diabetes diagnosis and care in sub-Saharan Africa: pooled analysis of individual data from 12 countries. The Lancet Diabetes & Endocrinology, 4(11), 903–912. https://doi.org/10.1016/S2213-8587(16)30181-4

Maraba, N., Karat, A. S., McCarthy, K., Churchyard, G. J., Charalambous, S., Kahn, K., … Chihota, V. (2016). Verbal autopsy-assigned causes of death among adults being investigated for TB in South Africa. Transactions of The Royal Society of Tropical Medicine and Hygiene, 110(9), 510–516. https://doi.org/10.1093/trstmh/trw058

Marston, M., Nakiyingi-Miiro, J., Hosegood, V., Lutalo, T., Mtenga, B., Zaba, B., & on behalf of the ALPHA network. (2016). Measuring the Impact of Antiretroviral Therapy Roll-Out on Population Level Fertility in Three African Countries. PLOS ONE, 11(3), e0151877. https://doi.org/10.1371/journal.pone.0151877

Masum, A. K. M., Azad, M. A. K., Hoque, K. E., Beh, L.-. S., Wanke, P., & Arslan, Ö. (2016). Job satisfaction and intention to quit: an empirical analysis of nurses in Turkey. PeerJ, 4. https://doi.org/10.7717/peerj.1896

Matthews, P. C., Carlson, J. M., Beloukas, A., Malik, A., Jooste, P., Ogwu, A., … Klenerman, P. (2016). HLA-A is a Predictor of Hepatitis B e Antigen Status in HIV-Positive African Adults. Journal of Infectious Diseases, 213(8), 1248–1252. https://doi.org/10.1093/infdis/jiv592

McGovern, M. E., Herbst, K., Tanser, F., Mutevedzi, T., Canning, D., Gareta, D., … Bärnighausen, T. (2016). Do gifts increase consent to home-based HIV testing? A difference-in-differences study in rural KwaZulu-Natal, South Africa. International Journal of Epidemiology, 45(6), 2100–2109. https://doi.org/10.1093/ije/dyw122

Mitchell, J. M., Rochat, T. J., Houle, B., Stein, A., Newell, M. L., & Bland, R. M. (2016). The effect of maternal and child early life factors on grade repetition among HIV exposed and unexposed children in rural KwaZulu-Natal, South Africa. Journal of Developmental Origins of Health and Disease, 7(02), 185–196. https://doi.org/10.1017/S2040174415007230

Mitchell, J., Wight, M., Van Heerden, A., & Rochat, T. J. (2016). Intimate partner violence, HIV, and mental health: a triple epidemic of global proportions. International Review of Psychiatry, 28(5), 452–463. https://doi.org/10.1080/09540261.2016.1217829

Moshabela, M., Zuma, T., Orne-Gliemann, J., Iwuji, C., Larmarange, J., McGrath, N., & on behalf of the ANRS 12249 TasP Study Group. (2016). “It is better to die”: experiences of traditional health practitioners within the HIV treatment as prevention trial communities in rural South Africa (ANRS 12249 TasP trial). AIDS Care, 28(sup3), 24–32. https://doi.org/10.1080/09540121.2016.1181296

Moyo, S., Vandormael, A., Wilkinson, E., Engelbrecht, S., Gaseitsiwe, S., Kotokwe, K. P., … de Oliveira, T. (2016). Analysis of Viral Diversity in Relation to the Recency of HIV-1C Infection in Botswana. PLOS ONE, 11(8), e0160649. https://doi.org/10.1371/journal.pone.0160649

Mthiyane, T., Pym, A., Dheda, K., Rustomjee, R., Reddy, T., & Manie, S. (2016). Longitudinal assessment of health related quality of life of HIV infected patients treated for tuberculosis and HIV in a high burden setting. Quality of Life Research, 25(12), 3067–3076. https://doi.org/10.1007/s11136-016-1332-4

Muenchhoff, M., Adland, E., Karimanzira, O., Crowther, C., Pace, M., Csala, A., … Goulder, P. (2016). Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection. Science Translational Medicine, 8(358), 358ra125-358ra125. https://doi.org/10.1126/scitranslmed.aag1048

Muenchhoff, M., Healy, M., Singh, R., Roider, J., Groll, A., Kindra, C., … Archary, M. (2017). Malnutrition in HIV-Infected Children Is an Indicator of Severe Disease with an Impaired Response to Antiretroviral Therapy. AIDS Research and Human Retroviruses. https://doi.org/10.1089/aid.2016.0261

Naburi, H., Mujinja, P., Kilewo, C., Bärnighausen, T., Orsini, N., Manji, K., … Ekström, A. M. (2016). Predictors of Patient Dissatisfaction with Services for Prevention of Mother-To-Child Transmission of HIV in Dar es Salaam, Tanzania. PLOS ONE, 11(10), e0165121. https://doi.org/10.1371/journal.pone.0165121

Napua, M., Pfeiffer, J. T., Chale, F., Hoek, R., Manuel, J., Michel, C., … Sherr, K. (2016). Option B+ in Mozambique: formative research findings for the design of a facility-level clustered randomized controlled trial to improve ART retention in antenatal care. J Acquir Immune Defic Syndr, 72. https://doi.org/10.1097/QAI.0000000000001061

NCD Risk Factor Collaboration (NCD-RisC). (2016). A century of trends in adult human height. ELife, 5. https://doi.org/10.7554/eLife.13410

Newell, M.-L., & Iwuji, C. (2016). HIV treatment as prevention: applicable in sub-Saharan Africa? The Lancet Infectious Diseases, 16(7), 754–755. https://doi.org/10.1016/S1473-3099(16)30057-3

Noor, R. A., Geldsetzer, P., Bärnighausen, T., & Fawzi, W. (2016). Do countries rely on the World Health Organization for translating research findings into clinical guidelines? A case study. Globalization and Health, 12(1), 58. https://doi.org/10.1186/s12992-016-0196-2

Oldenburg, C. E., Bärnighausen, T., Tanser, F., Iwuji, C. C., De Gruttola, V., Seage, I., George R., … Harling, G. (2016). Antiretroviral Therapy to Prevent HIV Acquisition in Serodiscordant Couples in a Hyperendemic Community in Rural South Africa. Clinical Infectious Diseases, 63(4), 548–554. https://doi.org/10.1093/cid/ciw335

Oldenburg, C. E., Bärnighausen, T., Tanser, F., Iwuji, C. C., De Gruttola, V., Seage, G. R., … Harling, G. (2016a). Reply to Cohen et al. Clinical Infectious Diseases, 63(12), 1680.2-1680. https://doi.org/10.1093/cid/ciw674

Oldenburg, C. E., Bärnighausen, T., Tanser, F., Iwuji, C. C., De Gruttola, V., Seage, I., George R., … Harling, G. (2016b). Antiretroviral Therapy to Prevent HIV Acquisition in Serodiscordant Couples in a Hyperendemic Community in Rural South Africa. Clinical Infectious Diseases, 63(4), 548–554. https://doi.org/10.1093/cid/ciw335

Oldenburg, C. E., Moscoe, E., & Bärnighausen, T. (2016). Regression Discontinuity for Causal Effect Estimation in Epidemiology. Current Epidemiology Reports, 3(3), 233–241. https://doi.org/10.1007/s40471-016-0080-x

Oldenburg, C. E., Perez-Brumer, A. G., Reisner, S. L., Mayer, K. H., Mimiaga, M. J., Hatzenbuehler, M. L., & Bärnighausen, T. (2016). Human rights protections and HIV prevalence among MSM who sell sex: Cross-country comparisons from a systematic review and meta-analysis. Global Public Health, 1–12. https://doi.org/10.1080/17441692.2016.1149598

Ondenge, K., Renju, J., Bonnington, O., Moshabela, M., Wamoyi, J., Nyamukapa, C., … Skovdal, M. (2017). ‘I am treated well if I adhere to my HIV medication’: putting patient–provider interactions in context through insights from qualitative research in five sub-Saharan African countries. Sexually Transmitted Infections, 93(Suppl 3), e052973. https://doi.org/10.1136/sextrans-2016-052973

Orne-Gliemann, J., Zuma, T., Chikovore, J., Gillespie, N., Grant, M., Iwuji, C., … On Behalf of the TasP Study Group. (2016). Community perceptions of repeat HIV-testing: experiences of the ANRS 12249 Treatment as Prevention trial in rural South Africa. AIDS Care, 28(sup3), 14–23. https://doi.org/10.1080/09540121.2016.1164805

PANGEA_HIV Consortium, ICONIC Project, Yebra, G., Hodcroft, E. B., Ragonnet-Cronin, M. L., Pillay, D., … Kozlakidis, Z. (2016). Using nearly full-genome HIV sequence data improves phylogeny reconstruction in a simulated epidemic. Scientific Reports, 6(1). https://doi.org/10.1038/srep39489

Power, R. A., Parkhill, J., & de Oliveira, T. (2016). Microbial genome-wide association studies: lessons from human GWAS. Nature Reviews Genetics, 18(1), 41–50. https://doi.org/10.1038/nrg.2016.132

Reimers, P., Israel-Ballard, K., Spies, L., Tanser, F., Thior, I., Scott Gordon, W., & Coutsoudis, A. (2016). A Protocol for a Cluster Randomized Trial on the Effect of a “feeding buddy” Program on adherence to the Prevention of Mother-To-Child-Transmission Guidelines in a Rural Area of KwaZulu-Natal, South Africa. JAIDS Journal of Acquired Immune Deficiency Syndromes, 72. Retrieved from http://journals.lww.com/jaids/Fulltext/2016/08011/A_Protocol_for_a_Cluster_Randomized_Trial_on_the.6.aspx

Reniers, G., Wamukoya, M., Urassa, M., Nyaguara, A., Nakiyingi-Miiro, J., Lutalo, T., … Zaba, B. (2016). Data Resource Profile: Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa (ALPHA Network). International Journal of Epidemiology, 45(1), 83–93. https://doi.org/10.1093/ije/dyv343

Renju, J., Moshabela, M., McLean, E., Ddaaki, W., Skovdal, M., Odongo, F., … Wringe, A. (2017). ‘Side effects’ are ‘central effects’ that challenge retention in HIV treatment programmes in six sub-Saharan African countries: a multicountry qualitative study. Sexually Transmitted Infections, 93(Suppl 3), e052971. https://doi.org/10.1136/sextrans-2016-052971

Rochat, T. J., Mitchell, J., Lubbe, A. M., Stein, A., Tomlinson, M., & Bland, R. M. (2017). Communication about HIV and death: Maternal reports of primary school-aged children’s questions after maternal HIV disclosure in rural South Africa. Social Science & Medicine, 172, 124–134. https://doi.org/10.1016/j.socscimed.2016.10.031

Rochat, T. J., Mitchell, J., Stein, A., Mkwanazi, N. B., & Bland, R. M. (2016). The Amagugu Intervention: A Conceptual Framework for Increasing HIV Disclosure and Parent-Led Communication about Health among HIV-Infected Parents with HIV-Uninfected Primary School-Aged Children. Frontiers in Public Health, 4. https://doi.org/10.3389/fpubh.2016.00183

Saini, V., Cumming, B. M., Guidry, L., Lamprecht, D. A., Adamson, J. H., Reddy, V. P., … Steyn, A. J. C. (2016). Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosis. Cell Reports, 14(3), 572–585. https://doi.org/10.1016/j.celrep.2015.12.056

Seo, H. S., Kim, H., Hwang, S. M., Hong, S. H., & Lee, I. Y. (2016). Predictors of job satisfaction and burnout among tuberculosis management nurses and physicians. Epidemiol Health, 38. https://doi.org/10.4178/epih.e2016008

Shahmanesh, M., Schultze, A., Burns, F., Kirk, O., Lundgren, J., Mussini, C., … on behalf of EuroSIDA in EuroCOORD. (2016). The cardiovascular risk management for people living with HIV in Europe: how well are we doing? AIDS, 30(16). Retrieved from http://journals.lww.com/aidsonline/Fulltext/2016/10230/The_cardiovascular_risk_management_for_people.12.aspx

Simoni, Y., Fehlings, M., Kløverpris, H. N., McGovern, N., Koo, S.-L., Loh, C. Y., … Newell, E. W. (2017). Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency. Immunity, 46(1), 148–161. https://doi.org/10.1016/j.immuni.2016.11.005

Surolia, R., Karki, S., Wang, Z., Kulkarni, T., Li, F. J., Vohra, S., … Antony, V. B. (2016). Attenuated heme oxygenase-1 responses predispose the elderly to pulmonary nontuberculous mycobacterial infections. American Journal of Physiology - Lung Cellular and Molecular Physiology, 311(5), L928–L940. https://doi.org/10.1152/ajplung.00397.2015

Sutherland, K. A., Collier, D. A., Claiborne, D. T., Prince, J. L., Deymier, M. J., Goldstein, R. A., … Gupta, R. K. (2016). Wide variation in susceptibility of transmitted/founder HIV-1 subtype C Isolates to protease inhibitors and association with in vitro replication efficiency. Scientific Reports, 6(1). https://doi.org/10.1038/srep38153

The EuroCoord-CHAIN-EPPICC joint project study group, Ngo-Giang-Huong, N., Wittkop, L., Judd, A., Reiss, P., Goetghebuer, T., … Lallemant, M. (2016). Prevalence and effect of pre-treatment drug resistance on the virological response to antiretroviral treatment initiated in HIV-infected children – a EuroCoord-CHAIN-EPPICC joint project. BMC Infectious Diseases, 16(1). https://doi.org/10.1186/s12879-016-1968-2

Tlou, B., Sartorius, B., & Tanser, F. (2016). Spatial-temporal dynamics and structural determinants of child and maternal mortality in a rural, high HIV burdened South African population, 2000–2014: a study protocol. BMJ Open, 6(7), e010013. https://doi.org/10.1136/bmjopen-2015-010013

Treffry-Goatley, A., Lessells, R., Sykes, P., Bärnighausen, T., de Oliveira, T., Moletsane, R., & Seeley, J. (2016). Understanding Specific Contexts of Antiretroviral Therapy Adherence in Rural South Africa: A Thematic Analysis of Digital Stories from a Community with High HIV Prevalence. PLOS ONE, 11(2), e0148801. https://doi.org/10.1371/journal.pone.0148801

van Rooyen, H., Essack, Z., Rochat, T., Wight, D., Knight, L., Bland, R., & Celum, C. (2016). Taking HIV Testing to Families: Designing a Family-Based Intervention to Facilitate HIV Testing, Disclosure, and Intergenerational Communication. Frontiers in Public Health, 4. https://doi.org/10.3389/fpubh.2016.00154

Vandormael, A. M., Boulware, D. R., Tanser, F. C., Bärnighausen, T. W., Stott, K. E., & de Oliveira, T. (2016). Brief Report: Virologic Monitoring Can Be a Cost-Effective Strategy to Diagnose Treatment Failure on First-Line ART. Journal of Acquired Immune Deficiency Syndromes (1999), 71(4), 462–466. https://doi.org/10.1097/QAI.0000000000000870

Wamoyi, J., Renju, J., Moshabela, M., McLean, E., Nyato, D., Mbata, D., … Wringe, A. (2017). Understanding the relationship between couple dynamics and engagement with HIV care services: insights from a qualitative study in Eastern and Southern Africa. Sexually Transmitted Infections, 93(Suppl 3). https://doi.org/10.1136/sextrans-2016-052976

Wang, H., Bhutta, Z. A., Coates, M. M., Coggeshall, M., Dandona, L., Diallo, K., … Murray, C. J. L. (2016). Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1725–1774. https://doi.org/10.1016/S0140-6736(16)31575-6

Wang, H., Naghavi, M., Allen, C., Barber, R. M., Bhutta, Z. A., Carter, A., … Murray, C. J. L. (2016). Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1459–1544. https://doi.org/10.1016/S0140-6736(16)31012-1

Wang, H., Wolock, T. M., Carter, A., Nguyen, G., Kyu, H. H., Gakidou, E., … Murray, C. J. L. (2016). Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980–2015: the Global Burden of Disease Study 2015. The Lancet HIV, 3(8), e361–e387. https://doi.org/10.1016/S2352-3018(16)30087-X

Watters, S. A., Mlcochova, P., Maldarelli, F., Goonetilleke, N., Pillay, D., & Gupta, R. K. (2016). Sequential CCR5-Tropic HIV-1 Reactivation from Distinct Cellular Reservoirs following Perturbation of Elite Control. PLOS ONE, 11(7), e0158854. https://doi.org/10.1371/journal.pone.0158854

White, E., Smit, E., Churchill, D., Collins, S., Booth, C., Tostevin, A., … Dunn, D. T. (2016). No Evidence That HIV-1 Subtype C Infection Compromises the Efficacy of Tenofovir-Containing Regimens: Cohort Study in the United Kingdom. Journal of Infectious Diseases, 214(9), 1302–1308. https://doi.org/10.1093/infdis/jiw213

Yates, T. A., Tanser, F., & Abubakar, I. (2016). Plan Beta for tuberculosis: it’s time to think seriously about poorly ventilated congregate settings. The International Journal of Tuberculosis and Lung Disease, 20(1), 5–10. https://doi.org/10.5588/ijtld.15.0494

Zuma, T., Wight, D., Rochat, T., & Moshabela, M. (2016). The role of traditional health practitioners in Rural KwaZulu-Natal, South Africa: generic or mode specific? BMC Complementary and Alternative Medicine, 16(1). https://doi.org/10.1186/s12906-016-1293-8

June 2023 Publications

Krause, R., Warren, C. M., Simmons, J. D., Rebeiro, P. F., Maruri, F., Karim, F., Sterling, T. R., Koethe, J. R., Leslie, A., & Van Der Heijden, Y. F. (2023). Failure to decrease HbA1c levels following TB treatment is associated with elevated Th1/Th17 CD4+ responses. Frontiers in Immunology, 14, 1151528. https://doi.org/10.3389/fimmu.2023.1151528