Publications

2017 Publications

Aicken, C. R. H., Sutcliffe, L. J., Gibbs, J., Tickle, L. J., Hone, K., Harding-Esch, E. M., … Shahmanesh, M. (2017). Using the eSexual Health Clinic to access chlamydia treatment and care via the internet: a qualitative interview study. Sexually Transmitted Infections. https://doi.org/10.1136/sextrans-2017-053227

Akilimali, N. A., Chang, C. C., Muema, D. M., Reddy, T., Moosa, M.-Y. S., Lewin, S. R., … Ndung’u, T. (2017). Plasma But Not Cerebrospinal Fluid Interleukin 7 and Interleukin 5 Levels Pre–Antiretroviral Therapy Commencement Predict Cryptococcosis-Associated Immune Reconstitution Inflammatory Syndrome. Clinical Infectious Diseases, 65(9), 1551–1559. https://doi.org/10.1093/cid/cix598

Akullian, A., Bershteyn, A., Klein, D., Vandormael, A., Bärnighausen, T., & Tanser, F. (2017). Sexual partnership age pairings and risk of HIV acquisition in rural South Africa: AIDS, 31(12), 1755–1764. https://doi.org/10.1097/QAD.0000000000001553

Atun, R., Chang, A. Y., Ogbuoji, O., Silva, S., Resch, S., Hontelez, J., & Bärnighausen, T. (2016). Long-term financing needs for HIV control in sub-Saharan Africa in 2015–2050: a modelling study. BMJ Open, 6(3). https://doi.org/10.1136/bmjopen-2015-009656

Baijnath, S., Moodley, C., Ngcobo, B., Singh, S. D., Kruger, H. G., Arvidsson, P. I., … Govender, T. (2017). Clofazimine protects against mycobacterium tuberculosis dissemination in the CNS following an aerosol challenge in a murine model. International Journal of Antimicrobial Agents. https://doi.org/10.1016/j.ijantimicag.2017.08.020

Barichievy, S., Naidoo, J., Boulle, M., Scholefield, J., Parihar, S. P., Coussens, A. K., … Mhlanga, M. M. (2017). Viral apoptosis evasion via the MAPK pathway by use of a host long noncoding RNA. https://doi.org/10.1101/153130

Bärnighausen, T. (2017). Population health intervention research: three important advancements. International Journal of Public Health. https://doi.org/10.1007/s00038-017-0985-2

Bernays, S., Bukenya, D., Thompson, C., Ssembajja, F., & Seeley, J. (2017). Being an ‘adolescent’: The consequences of gendered risks for young people in rural Uganda. Childhood, 0907568217732119. https://doi.org/10.1177/0907568217732119

Bhattacharya, D., Danaviah, S., Muema, D. M., Akilimali, N. A., Moodley, P., Ndung’u, T., & Das, G. (2017). Cellular Architecture of Spinal Granulomas and the Immunological Response in Tuberculosis Patients Coinfected with HIV. Frontiers in Immunology, 8, 1120. https://doi.org/10.3389/fimmu.2017.01120

Bohlius, J. (2017). Comparison of Kaposi sarcoma risk in HIV-positive adults across five continents: a multiregional multicohort study. Clinical Infectious Diseases. https://doi.org/10.1093/cid/cix480

Bor, J., Ahmed, S., Fox, M. P., Rosen, S., Meyer-Rath, G., Katz, I. T., … Bärnighausen, T. (2017). Effect of eliminating CD4-count thresholds on HIV treatment initiation in South Africa: An empirical modeling study. PLOS ONE, 12(6), e0178249. https://doi.org/10.1371/journal.pone.0178249

Bor, J., Chiu, C., Ahmed, S., Katz, I., Fox, M., Rosen, S., … Bärnighausen, T. (2017). Failure to initiate HIV treatment in patients with high CD4 counts: evidence from demographic surveillance in rural KwaZulu-Natal. Tropical Medicine & International Health, n/a-n/a. https://doi.org/10.1111/tmi.13013

Brennan, A. T., Davies, M.-A., Bor, J., Wandeler, G., Stinson, K., Wood, R., … Fox, M. P. (2017). Has the phasing out of stavudine in accordance with changes in WHO guidelines led to a decrease in single-drug substitutions in first-line antiretroviral therapy for HIV in sub-Saharan Africa? AIDS, 31(1). Retrieved from http://journals.lww.com/aidsonline/Fulltext/2017/01020/Has_the_phasing_out_of_stavudine_in_accordance.16.aspx

Bukenya, D., Wringe, A., Moshabela, M., Skovdal, M., Ssekubugu, R., Paparini, S., … Seeley, J. (2017). Where are we now? A multicountry qualitative study to explore access to pre-antiretroviral care services: a precursor to antiretroviral therapy initiation. Sexually Transmitted Infections, 93(Suppl 3). https://doi.org/10.1136/sextrans-2016-052970

Chanda, M. M., Ortblad, K. F., Mwale, M., Chongo, S., Kanchele, C., Kamungoma, N., … Oldenburg, C. E. (2017). Contraceptive use and unplanned pregnancy among female sex workers in Zambia. Contraception, 96(3), 196–202. https://doi.org/10.1016/j.contraception.2017.07.003

Chang, C. C., Kangethe, R., Omarjee, S., Hiramen, K., Gosnell, B., Sojane, K., … Ndung’u, T. (2017). Relationship of Human Immunodeficiency Virus Viral Load in Cerebrospinal Fluid and Plasma in Patients Co-infected With Cryptococcal Meningitis. Open Forum Infectious Diseases, 4(2). https://doi.org/10.1093/ofid/ofx032

Collier, D., Iwuji, C., Derache, A., de Oliveira, T., Okesola, N., Calmy, A., … Gupta, R. K. (2017). Virological Outcomes of Second-line Protease Inhibitor–Based Treatment for Human Immunodeficiency Virus Type 1 in a High-Prevalence Rural South African Setting: A Competing-Risks Prospective Cohort Analysis. Clinical Infectious Diseases, 64(8), 1006–1016. https://doi.org/10.1093/cid/cix015

Cordes, J. L., Stangl, A., Krishnaratne, S., Hoddinott, G., Mathema, H., Bond, V., … Hargreaves, J. R. (2017). Trends in Responses to DHS Questions Should Not Be Interpreted as Reflecting an Increase in “Anticipated Stigma” in Africa: JAIDS Journal of Acquired Immune Deficiency Syndromes, 75(1), e22–e23. https://doi.org/10.1097/QAI.0000000000001328

Cornell, M., Johnson, L. F., Wood, R., Tanser, F., Fox, M. P., Prozesky, H., … Boulle, A. (2017). Twelve-year mortality in adults initiating antiretroviral therapy in South Africa. Journal of the International AIDS Society, 20(1). https://doi.org/10.7448/IAS.20.1.21902

Cox, H., Dickson-Hall, L., Ndjeka, N., van’t Hoog, A., Grant, A., Cobelens, F., … Nicol, M. (2017). Delays and loss to follow-up before treatment of drug-resistant tuberculosis following implementation of Xpert MTB/RIF in South Africa: A retrospective cohort study. PLOS Medicine, 14(2), e1002238. https://doi.org/10.1371/journal.pmed.1002238

Cuadros, D. F., Li, J., Branscum, A. J., Akullian, A., Jia, P., Mziray, E. N., & Tanser, F. (2017). Mapping the spatial variability of HIV infection in Sub-Saharan Africa: Effective information for localized HIV prevention and control. Scientific Reports, 7(1), 9093. https://doi.org/10.1038/s41598-017-09464-y

Cumming, B. M., Chinta, K. C., Reddy, V. P., & Steyn, A. J. C. (2017). Role of Ergothioneine in Microbial Physiology and Pathogenesis. Antioxidants & Redox Signaling. https://doi.org/10.1089/ars.2017.7300

Cumming, B. M., Rahman, M. A., Lamprecht, D. A., Rohde, K. H., Saini, V., Adamson, J. H., … Steyn, A. J. C. (2017). Mycobacterium tuberculosis arrests host cycle at the G1/S transition to establish long term infection. PLOS Pathogens, 13(5), e1006389. https://doi.org/10.1371/journal.ppat.1006389

De Neve, J.-W., & Harling, G. (2017). Offspring schooling associated with increased parental survival in rural KwaZulu-Natal, South Africa. Social Science & Medicine, 176, 149–157. https://doi.org/10.1016/j.socscimed.2017.01.015

de Welzen, L., Eldholm, V., Maharaj, K., Manson, A. L., Earl, A. M., & Pym, A. S. (2017). Whole transcriptome and genomic analysis of extensively drug-resistant Mycobacterium tuberculosis clinical isolates identifies downregulation of ethA as a mechanism of ethionamide resistance. Antimicrobial Agents and Chemotherapyhttps://doi.org/10.1128/AAC.01461-17

Dobra, A., Bärnighausen, T., Vandormael, A., & Tanser, F. (2017). Space-time migration patterns and risk of HIV acquisition in rural South Africa. AIDS (London, England), 31(1), 137–145. https://doi.org/10.1097/QAD.0000000000001292

Dong, K. L., Moodley, A., Kwon, D. S., Ghebremichael, M. S., Dong, M., Ismail, N., … Ndung’u, T. (n.d.). Detection and treatment of Fiebig stage I HIV-1 infection in young at-risk women in South Africa: a prospective cohort study. The Lancet HIVhttps://doi.org/10.1016/S2352-3018(17)30146-7

Dowdy, D. W., Grant, A. D., Dheda, K., Nardell, E., Fielding, K., & Moore, D. A. J. (2017). Designing and Evaluating Interventions to Halt the Transmission of Tuberculosis. The Journal of Infectious Diseases216(suppl_6), S654–S661. https://doi.org/10.1093/infdis/jix320 

Garrett, N. J., McGrath, N., & Mindel, A. (2017). Advancing STI care in low/middle-income countries: has STI syndromic management reached its use-by date? Sexually Transmitted Infections, 93(1), 4. https://doi.org/10.1136/sextrans-2016-052581

Gatuguta, A., Katusiime, B., Seeley, J., Colombini, M., Mwanzo, I., & Devries, K. (2017). Should community health workers offer support healthcare services to survivors of sexual violence? a systematic review. BMC International Health and Human Rights, 17(1), 28. https://doi.org/10.1186/s12914-017-0137-z

Geldsetzer, P., De Neve, J.-W., Boudreaux, C., Bärnighausen, T., & Bossert, T. J. (2017). Improving the performance of community health workers in Swaziland: findings from a qualitative study. Human Resources for Health, 15(1), 68. https://doi.org/10.1186/s12960-017-0236-x

Geldsetzer, P., Feigl, A. B., Tanser, F., Gareta, D., Pillay, D., & Bärnighausen, T. (2017). Population-level decline in BMI and systolic blood pressure following mass HIV treatment: Evidence from rural KwaZulu-Natal: Decline in BMI and BP following Mass HIV Treatment. Obesity, 25(1), 200–206. https://doi.org/10.1002/oby.21663

Godfrey, C., Thigpen, M. C., Crawford, K. W., Jean-Phillippe, P., Pillay, D., Persaud, D., … Fitzgibbon, J. (2017). Global HIV Antiretroviral Drug Resistance. The Journal of Infectious Diseases. https://doi.org/10.1093/infdis/jix137

Goodall, R. L., Dunn, D. T., Nkurunziza, P., Mugarura, L., Pattery, T., Munderi, P., … Gupta, R. K. (2017). Rapid accumulation of HIV-1 thymidine analogue mutations and phenotypic impact following prolonged viral failure on zidovudine-based first-line ART in sub-Saharan Africa. Journal of Antimicrobial Chemotherapy, 72(5), 1450–1455. https://doi.org/10.1093/jac/dkw583

Gounder, K., Oyaro, M., Padayachi, N., Zulu, T. M., de Oliveira, T., Wylie, J., & Ndung’u, T. (2017). Complex Subtype Diversity of HIV-1 Among Drug Users in Major Kenyan Cities. AIDS Research and Human Retroviruses, 33(5), 500–510. https://doi.org/10.1089/aid.2016.0321

Haber, N., Tanser, F., Bor, J., Naidu, K., Mutevedzi, T., Herbst, K., … Bärnighausen, T. (2017). From HIV infection to therapeutic response: a population-based longitudinal HIV cascade-of-care study in KwaZulu-Natal, South Africa. The Lancet HIV, 4(5), e223–e230. https://doi.org/10.1016/S2352-3018(16)30224-7

Hainsworth, E. G., Shahmanesh, M., & Stevenson, F. (2017). Exploring the views and experiences of HIV positive patients treated for cancer: a systematic review of the literature. AIDS Care, 1–9. https://doi.org/10.1080/09540121.2017.1381332

Hanifa, Y., Fielding, K. L., Chihota, V. N., Adonis, L., Charalambous, S., Foster, N., … Grant, A. D. (2017). A clinical scoring system to prioritise investigation for tuberculosis among adults attending HIV clinics in South Africa. PLOS ONE, 12(8), e0181519. https://doi.org/10.1371/journal.pone.0181519

Harling, G., Gumede, D., Mutevedzi, T., McGrath, N., Seeley, J., Pillay, D., … Herbst, A. J. (2017). The impact of self-interviews on response patterns for sensitive topics: a randomized trial of electronic delivery methods for a sexual behaviour questionnaire in rural South Africa. BMC Medical Research Methodology, 17(1), 125. https://doi.org/10.1186/s12874-017-0403-8

 Harling, G., McGrath, N., Seeley, J., BBrnighausen, T. W., & Herbst, A. J. (2017). The Advantages and Disadvantages of Self-Interviews for Sensitive Topics: A Randomized Trial of Electronic Delivery Methods for a Sexual Behaviour Questionnaire in Rural South Africa. SSRN Electronic Journal. https://doi.org/10.2139/ssrn.2945424

Harvala, H., Frampton, D., Grant, P., Raffle, J., Ferns, R. B., Kozlakidis, Z., … For the ICONIC Consortium. (2017). Emergence of a novel subclade of influenza A(H3N2) virus in London, December 2016 to January 2017. Eurosurveillance, 22(8). https://doi.org/10.2807/1560-7917.ES.2017.22.8.30466

Helova, A., Akama, E., Bukusi, E. A., Musoke, P., Nalwa, W. Z., Odeny, T. A., … Abuogi, L. L. (2017). Health facility challenges to the provision of Option B+ in western Kenya: a qualitative study. Health Policy Plan, 32.

Iwuji C, Orne-Gliemann J, Balestre E, Larmarange J, Thiebaut R, Tanser F, et al. Abstract: The impact of universal test and treat on HIV incidence in a rural South African population: ANRS 12249 TasP trial, 2012-2016. In: International AIDS Conference 2016, Durban, South Africa. Durban; 2016. http://programme.aids2016.org/Abstract/Abstract/10537 . (n.d.). Retrieved from http://programme.aids2016.org/Abstract/Abstract/10537

Jackson, L., Hunter, J., Cele, S., Ferreira, I. M., Young, A., Karim, F., … Sigal, A. (2017). Incomplete inhibition of HIV infection results in more HIV infected lymph node cells by reducing cell death. https://doi.org/10.1101/163352

Jardim, T. V., Reiger, S., Abrahams-Gessel, S., Gomez-Olive, F. X., Wagner, R. G., Wade, A., … Gaziano, T. A. (2017). Hypertension management in a population of older adults in rural South Africa: Journal of Hypertension, 35(6), 1283–1289. https://doi.org/10.1097/HJH.0000000000001312

Karat, A. S., Tlali, M., Fielding, K. L., Charalambous, S., Chihota, V. N., Churchyard, G. J., … Grant, A. D. (2017). Measuring mortality due to HIV-associated tuberculosis among adults in South Africa: Comparing verbal autopsy, minimally-invasive autopsy, and research data. PLOS ONE, 12(3), e0174097. https://doi.org/10.1371/journal.pone.0174097

Kaufmann, S. H. E., Dockrell, H. M., Drager, N., Ho, M. M., McShane, H., Neyrolles, O., … Hogarth, P. (2017). TBVAC2020: Advancing Tuberculosis Vaccines from Discovery to Clinical Development. Frontiers in Immunology, 8, 1203. https://doi.org/10.3389/fimmu.2017.01203

Khatamzas, E., Hipp, M. M., Gaughan, D., Pichulik, T., Leslie, A., Fernandes, R. A., … Simmons, A. (2017). Snapin promotes HIV?1 transmission from dendritic cells by dampening TLR8 signaling. The EMBO Journal, 36(20), 2998. https://doi.org/10.15252/embj.201695364

Kiguoya, M. W., Mann, J. K., Chopera, D., Gounder, K., Lee, G. Q., Hunt, P. W., … Ndung’u, T. (2017). Subtype-Specific Differences in Gag-Protease-Driven Replication Capacity Are Consistent with Intersubtype Differences in HIV-1 Disease Progression. Journal of Virology, 91(13), e00253-17. https://doi.org/10.1128/JVI.00253-17

Kiwuwa-Muyingo, S., Nazziwa, J., Ssemwanga, D., Ilmonen, P., Njai, H., Ndembi, N., … Kaleebu, P. (2017). HIV-1 transmission networks in high risk fishing communities on the shores of Lake Victoria in Uganda: A phylogenetic and epidemiological approach. PLOS ONE, 12(10), e0185818. https://doi.org/10.1371/journal.pone.0185818

Kugathasan, R., Collier, D. A., Haddow, L. J., El Bouzidi, K., Edwards, S. G., Cartledge, J. D., … Gupta, R. K. (2017). Diffuse White Matter Signal Abnormalities on Magnetic Resonance Imaging Are Associated With Human Immunodeficiency Virus Type 1 Viral Escape in the Central Nervous System Among Patients With Neurological Symptoms. Clinical Infectious Diseases, 64(8), 1059–1065. https://doi.org/10.1093/cid/cix035

Laher, F., Ranasinghe, S., Porichis, F., Mewalal, N., Pretorius, K., Ismail, N., … Ndhlovu, Z. M. (2017). HIV Controllers Exhibit Enhanced Frequencies of Major Histocompatibility Complex Class II Tetramer + Gag-Specific CD4 + T Cells in Chronic Clade C HIV-1 Infection. Journal of Virology, 91(7), e02477-16. https://doi.org/10.1128/JVI.02477-16

Lampejo, T., Bruce, M., Teall, A., Dall’Antonia, M., Crawley-Boevey, E., Grant, P., … Nastouli, E. (2017). Caring for a patient with rabies: implications of the Milwaukee protocol for infection control and public health measures. Journal of Hospital Infection, 96(4), 385–391. https://doi.org/10.1016/j.jhin.2017.04.018

Lee, G. Q., Orlova-Fink, N., Einkauf, K., Chowdhury, F. Z., Sun, X., Harrington, S., … Lichterfeld, M. (2017). Clonal expansion of genome-intact HIV-1 in functionally polarized Th1 CD4+ T cells. Journal of Clinical Investigation, 127(7), 2689–2696. https://doi.org/10.1172/JCI93289

Leitman, E. M., Thobakgale, C. F., Adland, E., Ansari, M. A., Raghwani, J., Prendergast, A. J., … Goulder, P. J. R. (2017). Role of HIV-specific CD8+ T cells in pediatric HIV cure strategies after widespread early viral escape. The Journal of Experimental Medicine. https://doi.org/10.1084/jem.20162123

Lessells, R. J., Cooke, G. S., McGrath, N., Nicol, M. P., Newell, M.-L., & Godfrey-Faussett, P. (2017). Impact of Point-of-care Xpert MTB/RIF on Tuberculosis Treatment Initiation: A Cluster Randomised Trial. American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/rccm.201702-0278OC

Lewis, J., Payne, H., Walker, A. S., Otwombe, K., Gibb, D. M., Babiker, A. G., … Callard, R. E. (2017). Thymic Output and CD4 T-Cell Reconstitution in HIV-Infected Children on Early and Interrupted Antiretroviral Treatment: Evidence from the Children with HIV Early Antiretroviral Therapy Trial. Frontiers in Immunology, 8, 1162. https://doi.org/10.3389/fimmu.2017.01162

Mabuka, J. M., Dugast, A.-S., Muema, D. M., Reddy, T., Ramlakhan, Y., Euler, Z., … Ndung’u, T. (2017). Plasma CXCL13 but Not B Cell Frequencies in Acute HIV Infection Predicts Emergence of Cross-Neutralizing Antibodies. Frontiers in Immunology, 8, 1104. https://doi.org/10.3389/fimmu.2017.01104

Mahamed, D., Boulle, M., Ganga, Y., Mc Arthur, C., Skroch, S., Oom, L., … Sigal, A. (2017). Intracellular growth of Mycobacterium tuberculosis after macrophage cell death leads to serial killing of host cells. ELife, 6. https://doi.org/10.7554/eLife.22028

Maheu-Giroux, M., Tanser, F., Boily, M.-C., Pillay, D., Joseph, S. A., & Bärnighausen, T. (2017a). Determinants of time from HIV infection to linkage-to-care in rural KwaZulu-Natal, South Africa: AIDS, 31(7), 1017–1024. https://doi.org/10.1097/QAD.0000000000001435

Maheu-Giroux, M., Tanser, F., Boily, M.-C., Pillay, D., Joseph, S. A., & Bärnighausen, T. (2017b). Determinants of time from HIV infection to linkage-to-care in rural KwaZulu-Natal, South Africa: AIDS, 31(7), 1017–1024. https://doi.org/10.1097/QAD.0000000000001435

 Manne-Goehler, J., Siedner, M., Geldsetzer, P., Harling, G., Montana, L., Rohr, J., … Barnighausen, T. (2017). Leveraging the ART Advantage: diabetes and hypertension along the HIV care cascade in rural South Africa. Open Forum Infectious Diseases, 4(suppl_1), S58–S58. https://doi.org/10.1093/ofid/ofx162.137

Manson, A. L., Cohen, K. A., Abeel, T., Desjardins, C. A., Armstrong, D. T., Barry III, C. E., … Earl, A. M. (2017). Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance. Nat Genet, 49(3), 395–402.

Maskew, M., Bor, J., Hendrickson, C., MacLeod, W., Bärnighausen, T., Pillay, D., … Fox, M. P. (2017). Imputing HIV treatment start dates from routine laboratory data in South Africa: a validation study. BMC Health Services Research, 17(1), 41. https://doi.org/10.1186/s12913-016-1940-2

 Mitchell, J. M., Tomlinson, M., Bland, R. M., Houle, B., Stein, A., & Rochat, T. J. (2017). Confirmatory factor analysis of the Kaufman assessment battery in a sample of primary school-aged children in rural South Africa. South African Journal of Psychology, 0081246317741822. https://doi.org/10.1177/0081246317741822

Mkwanazi, N. B., Rochat, T. J., & Bland, R. M. (2017). The Amagugu intervention: a qualitative investigation into maternal experiences and perspectives of a maternal HIV disclosure support intervention in rural South Africa. Health Policy and Planning32(9), 1231–1240. https://doi.org/10.1093/heapol/czx056

Mlcochova, P., Sutherland, K. A., Watters, S. A., Bertoli, C., de Bruin, R. A., Rehwinkel, J., … Gupta, R. K. (2017). A G1?like state allows HIV?1 to bypass SAMHD1 restriction in macrophages. The EMBO Journal, 36(5), 604–616. https://doi.org/10.15252/embj.201696025

Mlcochova, P., Caswell, S. J., Taylor, I. A., Towers, G. J., & Gupta, R. K. (2017). DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV?1 infection of macrophages. The EMBO Journal, e201796880. https://doi.org/10.15252/embj.201796880

Moosa, A., Lamprecht, D. A., Arora, K., Barry, C. E., Boshoff, H. I. M., Ioerger, T. R., … Warner, D. F. (2017). Susceptibility of Mycobacterium tuberculosis Cytochrome bd Oxidase Mutants to Compounds Targeting the Terminal Respiratory Oxidase, Cytochrome c. Antimicrobial Agents and Chemotherapy, 61(10), e01338-17. https://doi.org/10.1128/AAC.01338-17

Moshabela, M., Bukenya, D., Darong, G., Wamoyi, J., McLean, E., Skovdal, M., … Wringe, A. (2017). Traditional healers, faith healers and medical practitioners: the contribution of medical pluralism to bottlenecks along the cascade of care for HIV/AIDS in Eastern and Southern Africa. Sexually Transmitted Infections, 93(Suppl 3), e052974. https://doi.org/10.1136/sextrans-2016-052974

Mudzengi, D., Sweeney, S., Hippner, P., Kufa, T., Fielding, K., Grant, A. D., … Vassall, A. (2017). The patient costs of care for those with TB and HIV: a cross-sectional study from South Africa. Health Policy and Planning. https://doi.org/10.1093/heapol/czw183

Muenchhoff, M., Healy, M., Singh, R., Roider, J., Groll, A., Kindra, C., … Archary, M. (2017). Malnutrition in HIV-Infected Children Is an Indicator of Severe Disease with an Impaired Response to Antiretroviral Therapy. AIDS Research and Human Retroviruses. https://doi.org/10.1089/aid.2016.0261

Mwimanzi, F., Toyoda, M., Mahiti, M., Mann, J. K., Martin, J. N., Bangsberg, D., … Ueno, T. (2017). Relative resistance of MHC-B to Nef-mediated downregulation is conserved among primate lentiviruses and influences antiviral T cell responses in HIV-1-infected individuals. Journal of Virology. https://doi.org/10.1128/JVI.01409-17

Naburi, H., Mujinja, P., Kilewo, C., Orsini, N., Bärnighausen, T., Manji, K., … Ekström, A. M. (2017). Job satisfaction and turnover intentions among health care staff providing services for prevention of mother-to-child transmission of HIV in Dar es Salaam, Tanzania. Human Resources for Health, 15, 61. https://doi.org/10.1186/s12960-017-0235-y

Naidoo, V. L., Mann, J. K., Noble, C., Adland, E., Carlson, J. M., Thomas, J., … Ndung’u, T. (2017). Mother-to-Child HIV Transmission Bottleneck Selects for Consensus Virus with Lower Gag-Protease-Driven Replication Capacity. Journal of Virology, 91(17), e00518-17. https://doi.org/10.1128/JVI.00518-17

Ngcapu, S., Theys, K., Libin, P., Marconi, C. V., Sunpath, H., Ndung’u, T., & Gordon, L. M. (2017). Characterization of Nucleoside Reverse Transcriptase Inhibitor-Associated Mutations in the RNase H Region of HIV-1 Subtype C Infected Individuals. Viruses9(11). https://doi.org/10.3390/v9110330

DART Virology Group, Dolling, D. I., Goodall, R. L., Chirara, M., Hakim, J., Nkurunziza, P., … Pillay, D. (2017). The virological durability of first-line ART among HIV-positive adult patients in resource limited settings without virological monitoring: a retrospective analysis of DART trial data. BMC Infectious Diseases, 17(1). https://doi.org/10.1186/s12879-017-2266-3

Ondenge, K., Renju, J., Bonnington, O., Moshabela, M., Wamoyi, J., Nyamukapa, C., … Skovdal, M. (2017). ‘I am treated well if I adhere to my HIV medication’: putting patient–provider interactions in context through insights from qualitative research in five sub-Saharan African countries. Sexually Transmitted Infections, 93(Suppl 3), e052973. https://doi.org/10.1136/sextrans-2016-052973

Paquette, R., Tanton, C., Burns, F., Prah, P., Shahmanesh, M., Field, N., … Mercer, C. H. (2017). Illicit drug use and its association with key sexual risk behaviours and outcomes: Findings from Britain’s third National Survey of Sexual Attitudes and Lifestyles (Natsal-3). PLoS ONE, 12(5), e0177922. https://doi.org/10.1371/journal.pone.0177922

Paredes, R., Tzou, P. L., van Zyl, G., Barrow, G., Camacho, R., Carmona, S., … Shafer, R. W. (2017). Collaborative update of a rule-based expert system for HIV-1 genotypic resistance test interpretation. PLOS ONE, 12(7), e0181357. https://doi.org/10.1371/journal.pone.0181357

Phillips, A. N., Stover, J., Cambiano, V., Nakagawa, F., Jordan, M. R., Pillay, D., … Bertagnolio, S. (2017). Impact of HIV Drug Resistance on HIV/AIDS-Associated Mortality, New Infections, and Antiretroviral Therapy Program Costs in Sub–Saharan Africa. The Journal of Infectious Diseases, 215(9), 1362–1365. https://doi.org/10.1093/infdis/jix089

Plazy, M., Perriat, D., Gumede, D., Boyer, S., Pillay, D., Dabis, F., Seeley, J., Orne-Gliemann, J. (2017). Implementing universal HIV treatment in a high HIV prevalence and rural South African setting – Field experiences and recommendations of health care providers. PLOS ONE12(11), e0186883. https://doi.org/10.1371/journal.pone.0186883

Power, R. A., Tansey, K. E., Buttenschøn, H. N., Cohen-Woods, S., Bigdeli, T., Hall, L. S., … Lewis, C. M. (2017). Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Biological Psychiatry, 81(4), 325–335. https://doi.org/10.1016/j.biopsych.2016.05.010

Price, H., Dunn, D., Zachary, T., Vudriko, T., Chirara, M., Kityo, C., … Gilson, R. (2017). Hepatitis B serological markers and plasma DNA concentrations: baseline results from a treatment-monitoring practices trial. AIDS, 31(8), 1109–1117. https://doi.org/10.1097/QAD.0000000000001454

Ratmann, O., Wymant, C., Colijn, C., Danaviah, S., Essex, M., Frost, S., … on behalf of the PANGEA-HIV Consort. (2017). HIV-1 Full-Genome Phylogenetics of Generalized Epidemics in Sub-Saharan Africa: Impact of Missing Nucleotide Characters in Next-Generation Sequences. AIDS Research and Human Retroviruses. https://doi.org/10.1089/aid.2017.0061

Reimers, P., Israel-Ballard, K., Craig, M., Spies, L., Thior, I., Tanser, F., & Coutsoudis, A. (2017). A Cluster Randomised Trial to Determine the Efficacy of the “Feeding Buddies” Programme in Improving Exclusive Breastfeeding Rates Among HIV-Infected Women in Rural KwaZulu-Natal, South Africa. AIDS and Behavior. https://doi.org/10.1007/s10461-017-1865-8

Reniers, G., Blom, S., Lieber, J., Herbst, A. J., Calvert, C., Bor, J., … Hosegood, V. (2017). Tuberculosis mortality and the male survival deficit in rural South Africa: An observational community cohort study. PLOS ONE, 12(10), e0185692. https://doi.org/10.1371/journal.pone.0185692

Renju, J., Moshabela, M., McLean, E., Ddaaki, W., Skovdal, M., Odongo, F., … Wringe, A. (2017). ‘Side effects’ are ‘central effects’ that challenge retention in HIV treatment programmes in six sub-Saharan African countries: a multicountry qualitative study. Sexually Transmitted Infections, 93(Suppl 3), e052971. https://doi.org/10.1136/sextrans-2016-052971

Report on the Global HIV/AIDS Epidemic. (2000). Geneva: UNAIDS.

Rhee, S.-Y., Varghese, V., Holmes, S. P., Van Zyl, G. U., Steegen, K., Boyd, M. A., … Shafer, R. W. (2017). Mutational Correlates of Virological Failure in Individuals Receiving a WHO-Recommended Tenofovir-Containing First-Line Regimen: An International Collaboration. EBioMedicine, 18(Supplement C), 225–235. https://doi.org/10.1016/j.ebiom.2017.03.024

Rochat, T. J., Mitchell, J., Lubbe, A. M., Stein, A., Tomlinson, M., & Bland, R. M. (2017). Communication about HIV and death: Maternal reports of primary school-aged children’s questions after maternal HIV disclosure in rural South Africa. Social Science & Medicine, 172, 124–134. https://doi.org/10.1016/j.socscimed.2016.10.031

Rochat, T. J., Houle, B., Stein, A., Pearson, R. M., Newell, M. L., & Bland, R. M. (2017). Cohort Profile: The Siyakhula Cohort, rural South Africa. International Journal of Epidemiology, dyx148-dyx148. https://doi.org/10.1093/ije/dyx148

Rochat, T. J., Stein, A., Cortina-Borja, M., Tanser, F., & Bland, R. M. (2017). The Amagugu intervention for disclosure of maternal HIV to uninfected primary school-aged children in South Africa: a randomised controlled trial. The Lancet HIV. https://doi.org/10.1016/S2352-3018(17)30133-9

Rohr, J. K., Xavier Gómez-Olivé, F., Rosenberg, M., Manne-Goehler, J., Geldsetzer, P., Wagner, R. G., … Bärnighausen, T. (2017). Performance of self-reported HIV status in determining true HIV status among older adults in rural South Africa: a validation study. Journal of the International AIDS Society, 20(1). https://doi.org/10.7448/IAS.20.1.21691

Rosenberg, M. S., Gómez-Olivé, F. X., Rohr, J. K., Houle, B. C., Kabudula, C. W., Wagner, R. G., … Bärnighausen, T. (2017). Sexual Behaviors and HIV Status: A Population-Based Study Among Older Adults in Rural South Africa. JAIDS Journal of Acquired Immune Deficiency Syndromes, 74(1), e9–e17. https://doi.org/10.1097/QAI.0000000000001173

Rossouw, T., Nieuwoudt, M., Manasa, J., Malherbe, G., Lessells, R., Pillay, S., … de Oliveira, T. (2017). HIV drug resistance levels in adults failing first-line antiretroviral therapy in an urban and a rural setting in South Africa. HIV Medicine, 18(2), 104–114. https://doi.org/10.1111/hiv.12400

Sanya, R. E., Tumwesige, E., Elliott, A. M., & Seeley, J. (2017). Perceptions about interventions to control schistosomiasis among the Lake Victoria island communities of Koome, Uganda. PLOS Neglected Tropical Diseases, 11(10), e0005982. https://doi.org/10.1371/journal.pntd.0005982

Schomaker, M., Leroy, V., Wolfs, T., Technau, K.-G., Renner, L., Judd, A., … Davies, M.-A. (2017). Optimal timing of antiretroviral treatment initiation in HIV-positive children and adolescents: a multiregional analysis from Southern Africa, West Africa and Europe. International Journal of Epidemiology, 46(2), 453–465. https://doi.org/10.1093/ije/dyw097

Schultze, A., Paredes, R., Sabin, C., Phillips, A. N., Pillay, D., Mackie, N., … Cozzi-Lepri, A. (2017). The association between detected drug resistance mutations and CD4+ T-cell decline in HIV-positive individuals maintained on a failing treatment regimen. Antiviral Therapy. https://doi.org/10.3851/IMP3178

Seeley, J. (2017). HIV diagnosis increasing in older adults in Europe. The Lancet HIV. https://doi.org/10.1016/S2352-3018(17)30151-0

Simoni, Y., Fehlings, M., Kløverpris, H. N., McGovern, N., Koo, S.-L., Loh, C. Y., … Newell, E. W. (2017). Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency. Immunity, 46(1), 148–161. https://doi.org/10.1016/j.immuni.2016.11.005

Siu, G. E., Wight, D., Seeley, J., Namutebi, C., Sekiwunga, R., Zalwango, F., & Kasule, S. (2017). Men’s Involvement in a Parenting Programme to Reduce Child Maltreatment and Gender-Based Violence: Formative Evaluation in Uganda. The European Journal of Development Research. https://doi.org/10.1057/s41287-017-0103-6

Skovdal, M., Wringe, A., Seeley, J., Renju, J., Paparini, S., Wamoyi, J., … Bonnington, O. (2017). Using theories of practice to understand HIV-positive persons varied engagement with HIV services: a qualitative study in six Sub-Saharan African countries. Sexually Transmitted Infections, 93(Suppl 3). https://doi.org/10.1136/sextrans-2016-052977

Ssali, A., Nunn, A., Mbonye, M., Anywaine, Z., & Seeley, J. (2017). Reasons for participating in a randomised clinical trial: The volunteers’ voices in the COSTOP trial in Uganda. Contemporary Clinical Trials Communications, 7(Supplement C), 44–47. https://doi.org/10.1016/j.conctc.2017.05.007

Suthar, A. B., Nagata, J. M., Nsanzimana, S., Bärnighausen, T., Negussie, E. K., & Doherty, M. C. (2017). Performance-based financing for improving HIV/AIDS service delivery: a systematic review. BMC Health Services Research, 17(1), 6. https://doi.org/10.1186/s12913-016-1962-9

Thayyil, S., Oliveira, V., Lally, P. J., Swamy, R., Bassett, P., Chandrasekaran, M., … Shankaran, S. (2017). Hypothermia for encephalopathy in low and middle-income countries (HELIX): study protocol for a randomised controlled trial. Trials, 18(1), 432. https://doi.org/10.1186/s13063-017-2165-3

Thobakgale, C., Naidoo, K., McKinnon, L. R., Werner, L., Samsunder, N., Karim, S. A., … Naidoo, K. (2017). Interleukin 1-Beta (IL-1β) Production by Innate Cells Following TLR Stimulation Correlates With TB Recurrence in ART-Treated HIV-Infected Patients. JAIDS Journal of Acquired Immune Deficiency Syndromes, 74(2). Retrieved from http://journals.lww.com/jaids/Fulltext/2017/02010/Interleukin_1_Beta__IL_1___Production_by_Innate.16.aspx

Titanji, B. K., Pillay, D., & Jolly, C. (2017). Combination antiretroviral therapy and cell–cell spread of wild-type and drug-resistant human immunodeficiency virus-1. Journal of General Virology, 98(4), 821–834. https://doi.org/10.1099/jgv.0.000728

Tlou, B., Sartorius, B., & Tanser, F. (2017). Space-time patterns in maternal and mother mortality in a rural South African population with high HIV prevalence (2000–2014): results from a population-based cohort. BMC Public Health, 17(1). https://doi.org/10.1186/s12889-017-4463-9

Tlou, B., Sartorius, B., & Tanser, F. (2017). Space-time variations in child mortality in a rural South African population with high HIV prevalence (2000–2014). PLOS ONE, 12(8), e0182478. https://doi.org/10.1371/journal.pone.0182478

Tomita, A., Vandormael, A. M., Bärnighausen, T., de Oliveira, T., & Tanser, F. (2017). Social Disequilibrium and the Risk of HIV Acquisition: A Multilevel Study in Rural KwaZulu-Natal Province, South Africa. JAIDS Journal of Acquired Immune Deficiency Syndromes, 75(2), 164–174. https://doi.org/10.1097/QAI.0000000000001349

 

Tomita, A., Vandormael, A. M., Cuadros, D., Di Minin, E., Heikinheimo, V., Tanser, F., … Burns, J. K. (2017). Green environment and incident depression in South Africa: a geospatial analysis and mental health implications in a resource-limited setting. The Lancet Planetary Health, 1(4), e152–e162. https://doi.org/10.1016/S2542-5196(17)30063-3

Tostevin, A., White, E., Dunn, D., Croxford, S., Delpech, V., Williams, I., … Bradley?Stewart, A. (2017). Recent trends and patterns in HIV?1 transmitted drug resistance in the United Kingdom. HIV Medicine, 18(3), 204–213. https://doi.org/10.1111/hiv.12414 

Turbé, V., Gray, E. R., Lawson, V. E., Nastouli, E., Brookes, J. C., Weiss, R. A., … McKendry, R. A. (2017). Towards an ultra-rapid smartphone- connected test for infectious diseases. Scientific Reports, 7(1), 11971. https://doi.org/10.1038/s41598-017-11887-6

van der Heijden, Y. F., Karim, F., Mufamadi, G., Zako, L., Chinappa, T., Shepherd, B. E., … Pym, A. S. (2017). Isoniazid-monoresistant tuberculosis is associated with poor treatment outcomes in Durban, South Africa. The International Journal of Tuberculosis and Lung Disease, 21(6), 670–676. https://doi.org/10.5588/ijtld.16.0843

Vandormael, A., Dobra, A., Bärnighausen, T., de Oliveira, T., & Tanser, F. (2017). Incidence rate estimation, periodic testing and the limitations of the mid-point imputation approach. International Journal of Epidemiologyhttps://doi.org/10.1093/ije/dyx134

Vassall, A., Siapka, M., Foster, N., Cunnama, L., Ramma, L., Fielding, K., … Sinanovic, E. (2017). Cost-effectiveness of Xpert MTB/RIF for tuberculosis diagnosis in South Africa: a real-world cost analysis and economic evaluation. The Lancet Global Health, 5(7), e710–e719. https://doi.org/10.1016/S2214-109X(17)30205-X

Vollmer, S., Harttgen, K., Alfven, T., Padayachy, J., Ghys, P., & Bärnighausen, T. (2017). The HIV Epidemic in Sub-Saharan Africa is Aging: Evidence from the Demographic and Health Surveys in Sub-Saharan Africa. AIDS and Behavior, 21(1), 101–113. https://doi.org/10.1007/s10461-016-1591-7

Vos, T., Allen, C., Arora, M., Barber, R. M., Bhutta, Z. A., Brown, A., … Murray, C. J. L. (2017). Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1545–1602. https://doi.org/10.1016/S0140-6736(16)31678-6

Walsh, F. J., Bärnighausen, T., Delva, W., Fleming, Y., Khumalo, G., Lejeune, C. L., … Okello, V. (2017). Impact of early initiation versus national standard of care of antiretroviral therapy in Swaziland’s public sector health system: study protocol for a stepped-wedge randomized trial. Trials, 18(1), 383. https://doi.org/10.1186/s13063-017-2128-8

White, E., Smit, E., Churchill, D., Collins, S., Booth, C., Tostevin, A., … Dunn, D. T. (2016). No Evidence That HIV-1 Subtype C Infection Compromises the Efficacy of Tenofovir-Containing Regimens: Cohort Study in the United Kingdom. Journal of Infectious Diseases, 214(9), 1302–1308. https://doi.org/10.1093/infdis/jiw213

Wong, E. B., Ndung’u, T., & Kasprowicz, V. O. (2017). The role of mucosal-associated invariant T cells in infectious diseases. Immunology, 150(1), 45–54.  https://doi.org/10.1111/imm.12673 

Wringe, A., Moshabela, M., Nyamukapa, C., Bukenya, D., Ondenge, K., Ddaaki, W., … Renju, J. (2017). HIV testing experiences and their implications for patient engagement with HIV care and treatment on the eve of ‘test and treat’: findings from a multicountry qualitative study. Sexually Transmitted Infections, 93(Suppl 3), e052969. https://doi.org/10.1136/sextrans-2016-052969

Wringe, A., Renju, J., Seeley, J., Moshabela, M., & Skovdal, M. (2017). Bottlenecks to HIV care and treatment in sub-Saharan Africa: a multi-country qualitative study. Sexually Transmitted Infections, 93(Suppl 3), e053172. https://doi.org/10.1136/sextrans-2017-053172

Yadon, A. N., Maharaj, K., Adamson, J. H., Lai, Y.-P., Sacchettini, J. C., Ioerger, T. R., … Pym, A. S. (2017). A comprehensive characterization of PncA polymorphisms that confer resistance to pyrazinamide. Nature Communications, 8(1), 588. https://doi.org/10.1038/s41467-017-00721-2

Yates, T. A., Khan, P. Y., Knight, G. M., Taylor, J. G., McHugh, T. D., Lipman, M., … Abubakar, I. (n.d.). The transmission of Mycobacterium tuberculosis in high burden settings. The Lancet Infectious Diseases, 16(2), 227–238. https://doi.org/10.1016/S1473-3099(15)00499-5

Yates, T. A., Tanser, F., & Abubakar, I. (2016). Plan Beta for tuberculosis: it’s time to think seriously about poorly ventilated congregate settings. The International Journal of Tuberculosis and Lung Disease, 20(1), 5–10. https://doi.org/10.5588/ijtld.15.0494

Zhou, B., Bentham, J., Di Cesare, M., Bixby, H., Danaei, G., Cowan, M. J., … Zuñiga Cisneros, J. (n.d.). Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants. The Lancet, 389(10064), 37–55. https://doi.org/10.1016/S0140-6736(16)31919-5

Zhukova, A., Cutino-Moguel, T., Gascuel, O., & Pillay, D. (2017). The Role of Phylogenetics as a Tool to Predict the Spread of Resistance. The Journal of Infectious Diseases, jix411-jix411. https://doi.org/10.1093/infdis/jix411

Zulu, M., Naidoo, K., Mncube, Z., Jaggernath, M., Goulder, P. J., Ndung’u, T., … Thobakgale, C. F. (2017). Reduced Expression of Siglec-7, NKG2A and CD57 on Terminally Differentiated CD56-CD16+ NK Cell Subset is associated with NK Cell Dysfunction in Chronic HIV-1 clade C Infection. AIDS Research and Human Retroviruseshttps://doi.org/10.1089/AID.2017.0095

2016 Publications

Aicken, C. R. H., Fuller, S. S., Sutcliffe, L. J., Estcourt, C. S., Gkatzidou, V., Oakeshott, P., … Shahmanesh, M. (2016). Young people’s perceptions of smartphone-enabled self-testing and online care for sexually transmitted infections: qualitative interview study. BMC Public Health, 16(1), 974. https://doi.org/10.1186/s12889-016-3648-y

Atun, R., Chang, A. Y., Ogbuoji, O., Silva, S., Resch, S., Hontelez, J., & Bärnighausen, T. (2016). Long-term financing needs for HIV control in sub-Saharan Africa in 2015–2050: a modelling study. BMJ Open, 6(3). https://doi.org/10.1136/bmjopen-2015-009656

Barnhart, D., Hertzmark, E., Liu, E., Mungure, E., Muya, A. N., Sando, D., … Spiegelman, D. (2016). Intra-cluster correlation estimates for HIV-related outcomes from care and treatment clinics in Dar es Salaam, Tanzania. Contemporary Clinical Trials Communications, 4, 161–169. https://doi.org/10.1016/j.conctc.2016.09.001

Bärnighausen, T., Bloom, D. E., & Humair, S. (2016). Human Resources for Treating HIV/AIDS: Are the Preventive Effects of Antiretroviral Treatment a Game Changer? PLOS ONE, 11(10), e0163960. https://doi.org/10.1371/journal.pone.0163960

BCCP: Botswana Combination Prevention Project. clinicaltrials.gov. 2015. https://clinicaltrials.gov/ct2/show/NCT01965470. Accessed 1 Sept 2016. (n.d.). Retrieved from https://clinicaltrials.gov/ct2/show/NCT01965470

Bohlius, J., Maxwell, N., Spoerri, A., Wainwright, R., Sawry, S., Poole, J., … for IeDEA-Southern Africa. (2016). Incidence of AIDS-Defining and Other Cancers in HIV-Positive Children in South Africa: Record Linkage Study. The Pediatric Infectious Disease Journal, 35(6), e164–e170. https://doi.org/10.1097/INF.0000000000001117

 

Boullé, M., Müller, T. G., Dähling, S., Ganga, Y., Jackson, L., Mahamed, D., … Sigal, A. (2016). HIV Cell-to-Cell Spread Results in Earlier Onset of Viral Gene Expression by Multiple Infections per Cell. PLOS Pathogens, 12(11), e1005964. https://doi.org/10.1371/journal.ppat.1005964

Boyer, S., Iwuji, C., Gosset, A., Protopopescu, C., Okesola, N., Plazy, M., … on behalf of the ANRS 12249 TasP study group. (2016). Factors associated with antiretroviral treatment initiation amongst HIV-positive individuals linked to care within a universal test and treat programme: early findings of the ANRS 12249 TasP trial in rural South Africa. AIDS Care, 28(Suppl 3), 39–51. https://doi.org/10.1080/09540121.2016.1164808

Brice, J., Sylla, M., Sayon, S., Telly, F., Bocar-Fofana, D., Murphy, R., … Maiga, A. I. (2016). Qualitative and quantitative HIV antibodies and viral reservoir size characterization in vertically infected children with virological suppression. Journal of Antimicrobial Chemotherapy, dkw537. https://doi.org/10.1093/jac/dkw537

Byrne, E. H., Anahtar, M. N., Cohen, K. E., Moodley, A., Padavattan, N., Ismail, N., … Kwon, D. S. (2016). Association between injectable progestin-only contraceptives and HIV acquisition and HIV target cell frequency in the female genital tract in South African women: a prospective cohort study. The Lancet Infectious Diseases, 16(4), 441–448. https://doi.org/10.1016/S1473-3099(15)00429-6

Carlson, J. M., Du, V. Y., Pfeifer, N., Bansal, A., Tan, V. Y. F., Power, K., … Goepfert, P. A. (2016). Impact of pre-adapted HIV transmission. Nature Medicine, 22(6), 606–613. https://doi.org/10.1038/nm.4100

Channon, M., Hosegood, V., & McGrath, N. (2016). A longitudinal population-based analysis of relationship status and mortality in KwaZulu-Natal, South Africa 2001–2011. Journal of Epidemiology and Community Health, 70(1), 56–64. https://doi.org/10.1136/jech-2014-205408

Chen, Z., Hu, Y., Cumming, B. M., Lu, P., Feng, L., Deng, J., … Chen, S. (n.d.). Mycobacterial WhiB6 Differentially Regulates ESX-1 and the Dos Regulon to Modulate Granuloma Formation and Virulence in Zebrafish. Cell Reports, 16(9), 2512–2524. https://doi.org/10.1016/j.celrep.2016.07.080

 Chetty, T., Thorne, C., Tanser, F., Bärnighausen, T., & Coutsoudis, A. (2016). Cohort profile: the Hlabisa pregnancy cohort, KwaZulu-Natal, South Africa. BMJ Open, 6(10), e012088. https://doi.org/10.1136/bmjopen-2016-012088

Chikovore, J., Gillespie, N., McGrath, N., Orne-Gliemann, J., Zuma, T., & On Behalf of the ANRS 12249 TasP Study Group. (2016). Men, masculinity, and engagement with treatment as prevention in KwaZulu-Natal, South Africa. AIDS Care, 28(sup3), 74–82. https://doi.org/10.1080/09540121.2016.1178953

Leitman, E. M., Thobakgale, C. F., Adland, E., Ansari, M. A., Raghwani, J., Prendergast, A. J., … Goulder, P. J. R. (2017). Role of HIV-specific CD8+ T cells in pediatric HIV cure strategies after widespread early viral escape. The Journal of Experimental Medicine. https://doi.org/10.1084/jem.20162123

Chinta, K. C., Saini, V., Glasgow, J. N., Mazorodze, J. H., Rahman, M. A., Reddy, D., … Steyn, A. J. C. (2016). The emerging role of gasotransmitters in the pathogenesis of tuberculosis. Nitric Oxide, 59, 28–41. https://doi.org/10.1016/j.niox.2016.06.009

Cohen, K. A., El-Hay, T., Wyres, K. L., Weissbrod, O., Munsamy, V., Yanover, C., … Pym, A. S. (n.d.). Paradoxical Hypersusceptibility of Drug-resistant Mycobacteriumtuberculosis to β-lactam Antibiotics. EBioMedicine, 9, 170–179. https://doi.org/10.1016/j.ebiom.2016.05.041

Conroy, A. A., McGrath, N., van Rooyen, H., Hosegood, V., Johnson, M. O., Fritz, K., … Darbes, L. A. (2016). Power and the association with relationship quality in South African couples: Implications for HIV/AIDS interventions. Social Science & Medicine, 153, 1–11. https://doi.org/10.1016/j.socscimed.2016.01.035

 Delva, W., Leventhal, G. E., & Helleringer, S. (2016). Connecting the dots: network data and models in HIV epidemiology. AIDS, 30. https://doi.org/10.1097/QAD.0000000000001184

Desjardins, C. A., Cohen, K. A., Munsamy, V., Abeel, T., Maharaj, K., Walker, B. J., … Pym, A. S. (2016). Genomic and functional analyses of Mycobacterium tuberculosis strains implicate ald in D-cycloserine resistance. Nature Genetics, 48(5), 544–551. https://doi.org/10.1038/ng.3548

Dimitrov, D. T., Boily, M.-C., Hallett, T. B., Albert, J., Boucher, C., Mellors, J. W., … van de Vijver, D. A. M. C. (2016). How Much Do We Know about Drug Resistance Due to PrEP Use? Analysis of Experts’ Opinion and Its Influence on the Projected Public Health Impact. PLoS ONE, 11(7), e0158620. https://doi.org/10.1371/journal.pone.0158620

 El Bouzidi, K., White, E., Mbisa, J. L., Sabin, C. A., Phillips, A. N., Mackie, N., … Dunn, D. T. (2016). HIV-1 drug resistance mutations emerging on darunavir therapy in PI-naive and -experienced patients in the UK. Journal of Antimicrobial Chemotherapy, 71(12), 3487–3494. https://doi.org/10.1093/jac/dkw343

Evangeli, M., Newell, M.-L., & McGrath, N. (2016). Factors associated with pre-ART loss-to-follow up in adults in rural KwaZulu-Natal, South Africa: a prospective cohort study. BMC Public Health, 16(1), 358. https://doi.org/10.1186/s12889-016-3025-x

Feigl, A. B., Bloom, D. E., Danaei, G., Pillay, D., Salomon, J. A., Tanser, F., & Bärnighausen, T. W. (2016). The Effect of HIV and the Modifying Effect of Anti-Retroviral Therapy (ART) on Body Mass Index (BMI) and Blood Pressure Levels in Rural South Africa. PLOS ONE, 11(8), e0158264. https://doi.org/10.1371/journal.pone.0158264

Ferns, R. B., Tarr, A. W., Hue, S., Urbanowicz, R. A., McClure, C. P., Gilson, R., … Pillay, D. (2016). Hepatitis C virus quasispecies and pseudotype analysis from acute infection to chronicity in HIV-1 co-infected individuals. Virology, 492, 213–224. https://doi.org/10.1016/j.virol.2016.02.003

Fox, M. P., Rosen, S., Geldsetzer, P., Bärnighausen, T., Negussie, E., & Beanland, R. (2016). Interventions to improve the rate or timing of initiation of antiretroviral therapy for HIV in sub-Saharan Africa: meta-analyses of effectiveness. Journal of the International AIDS Society, 19(1). https://doi.org/10.7448/IAS.19.1.20888

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Geldsetzer, P., Fink, G., Vaikath, M., & Bärnighausen, T. (2016). Sampling for Patient Exit Interviews: Assessment of Methods Using Mathematical Derivation and Computer Simulations. Health Services Research. https://doi.org/10.1111/1475-6773.12611

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Geldsetzer, P., Yapa, H. M. N., Vaikath, M., Ogbuoji, O., Fox, M. P., Essajee, S. M., … Bärnighausen, T. (2016). A systematic review of interventions to improve postpartum retention of women in PMTCT and ART care. Journal of the International AIDS Society, 19(1). https://doi.org/10.7448/IAS.19.1.20679

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Harling, G., & Bärnighausen, T. (2016). The role of partners’ educational attainment in the association between HIV and education amongst women in seven sub-Saharan African countries. Journal of the International AIDS Society, 19(1). https://doi.org/10.7448/IAS.19.1.20038

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Kaposi Sarcoma Risk in HIV-Infected Children and Adolescents on Combination Antiretroviral Therapy From Sub-Saharan Africa, Europe, and Asia. (2016). Clinical Infectious Diseases, ciw519. https://doi.org/10.1093/cid/ciw519

Karat, A. S., Omar, T., von Gottberg, A., Tlali, M., Chihota, V. N., Churchyard, G. J., … Grant, A. D. (2016). Autopsy Prevalence of Tuberculosis and Other Potentially Treatable Infections among Adults with Advanced HIV Enrolled in Out-Patient Care in South Africa. PLOS ONE, 11(11), e0166158. https://doi.org/10.1371/journal.pone.0166158

Karnon, J., & Orji, N. (2016). Option B+ for the prevention of mother-to-child transmission of HIV infection in developing countries: a review of published cost-effectiveness analyses. Health Policy Plan, 31. https://doi.org/10.1093/heapol/czw025

Kasprowicz, V. O., Cheng, T.-Y., Ndung’u, T., Sunpath, H., Moody, D. B., & Kasmar, A. G. (2016). HIV Disrupts Human T Cells That Target Mycobacterial Glycolipids. Journal of Infectious Diseases, 213(4), 628–633. https://doi.org/10.1093/infdis/jiv455

Kassebaum, N. J., Arora, M., Barber, R. M., Bhutta, Z. A., Brown, J., Carter, A., … Murray, C. J. L. (2016). Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1603–1658. https://doi.org/10.1016/S0140-6736(16)31460-X

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Khatamzas, E., Hipp, M. M., Gaughan, D., Pichulik, T., Leslie, A., Fernandes, R. A., … Simmons, A. (2017). Snapin promotes HIV?1 transmission from dendritic cells by dampening TLR8 signaling. The EMBO Journal, 36(20), 2998. https://doi.org/10.15252/embj.201695364

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Koofhethile, C. K., Ndhlovu, Z. M., Thobakgale-Tshabalala, C., Prado, J. G., Ismail, N., Mncube, Z., … Ndung’u, T. (2016). CD8 + T Cell Breadth and Ex Vivo Virus Inhibition Capacity Distinguish between Viremic Controllers with and without Protective HLA Class I Alleles. Journal of Virology, 90(15), 6818–6831. https://doi.org/10.1128/JVI.00276-16

Koto, M. V., & Maharaj, P. (2016). Difficulties facing healthcare workers in the era of AIDS treatment in Lesotho. Sahara J, 13. https://doi.org/10.1080/17290376.2016.1179588

Lamprecht, D. A., Finin, P. M., Rahman, M. A., Cumming, B. M., Russell, S. L., Jonnala, S. R., … Steyn, A. J. C. (2016). Turning the respiratory flexibility of Mycobacterium tuberculosis against itself. Nature Communications, 7, 12393. https://doi.org/10.1038/ncomms12393

Leitman, E. M., Hurst, J., Mori, M., Kublin, J., Ndung’u, T., Walker, B. D., … Goulder, P. J. R. (2016). Lower Viral Loads and Slower CD4+ T-Cell Count Decline in MRKAd5 HIV-1 Vaccinees Expressing Disease-Susceptible HLA-B*58:02. The Journal of Infectious Diseases, 214(3), 379–389. https://doi.org/10.1093/infdis/jiw093

Madlala, P., Singh, R., An, P., Werner, L., Mlisana, K., Abdool Karim, S. S., … Ndung’u, T. (2016). Association of Polymorphisms in the Regulatory Region of the Cyclophilin a Gene (PPIA) with Gene Expression and HIV/AIDS Disease Progression. JAIDS Journal of Acquired Immune Deficiency Syndromes, 72(5). Retrieved from http://journals.lww.com/jaids/Fulltext/2016/08150/Association_of_Polymorphisms_in_the_Regulatory.1.aspx

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Manne-Goehler, J., Atun, R., Stokes, A., Goehler, A., Houinato, D., Houehanou, C., … Bärnighausen, T. (2016). Diabetes diagnosis and care in sub-Saharan Africa: pooled analysis of individual data from 12 countries. The Lancet Diabetes & Endocrinology, 4(11), 903–912. https://doi.org/10.1016/S2213-8587(16)30181-4

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Marston, M., Nakiyingi-Miiro, J., Hosegood, V., Lutalo, T., Mtenga, B., Zaba, B., & on behalf of the ALPHA network. (2016). Measuring the Impact of Antiretroviral Therapy Roll-Out on Population Level Fertility in Three African Countries. PLOS ONE, 11(3), e0151877. https://doi.org/10.1371/journal.pone.0151877

Masum, A. K. M., Azad, M. A. K., Hoque, K. E., Beh, L.-. S., Wanke, P., & Arslan, Ö. (2016). Job satisfaction and intention to quit: an empirical analysis of nurses in Turkey. PeerJ, 4. https://doi.org/10.7717/peerj.1896 

Matthews, P. C., Carlson, J. M., Beloukas, A., Malik, A., Jooste, P., Ogwu, A., … Klenerman, P. (2016). HLA-A is a Predictor of Hepatitis B e Antigen Status in HIV-Positive African Adults. Journal of Infectious Diseases, 213(8), 1248–1252. https://doi.org/10.1093/infdis/jiv592

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Mitchell, J. M., Rochat, T. J., Houle, B., Stein, A., Newell, M. L., & Bland, R. M. (2016). The effect of maternal and child early life factors on grade repetition among HIV exposed and unexposed children in rural KwaZulu-Natal, South Africa. Journal of Developmental Origins of Health and Disease, 7(02), 185–196. https://doi.org/10.1017/S2040174415007230

Mitchell, J., Wight, M., Van Heerden, A., & Rochat, T. J. (2016). Intimate partner violence, HIV, and mental health: a triple epidemic of global proportions. International Review of Psychiatry, 28(5), 452–463. https://doi.org/10.1080/09540261.2016.1217829

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Moshabela, M., Bukenya, D., Darong, G., Wamoyi, J., McLean, E., Skovdal, M., … Wringe, A. (2017). Traditional healers, faith healers and medical practitioners: the contribution of medical pluralism to bottlenecks along the cascade of care for HIV/AIDS in Eastern and Southern Africa. Sexually Transmitted Infections, 93(Suppl 3), e052974. https://doi.org/10.1136/sextrans-2016-052974

Moshabela, M., Zuma, T., Orne-Gliemann, J., Iwuji, C., Larmarange, J., McGrath, N., & on behalf of the ANRS 12249 TasP Study Group. (2016). “It is better to die”: experiences of traditional health practitioners within the HIV treatment as prevention trial communities in rural South Africa (ANRS 12249 TasP trial). AIDS Care, 28(sup3), 24–32. https://doi.org/10.1080/09540121.2016.1181296

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Mthiyane, T., Pym, A., Dheda, K., Rustomjee, R., Reddy, T., & Manie, S. (2016). Longitudinal assessment of health related quality of life of HIV infected patients treated for tuberculosis and HIV in a high burden setting. Quality of Life Research, 25(12), 3067–3076. https://doi.org/10.1007/s11136-016-1332-4

Muenchhoff, M., Adland, E., Karimanzira, O., Crowther, C., Pace, M., Csala, A., … Goulder, P. (2016). Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection. Science Translational Medicine, 8(358), 358ra125-358ra125. https://doi.org/10.1126/scitranslmed.aag1048

Muenchhoff, M., Healy, M., Singh, R., Roider, J., Groll, A., Kindra, C., … Archary, M. (2017). Malnutrition in HIV-Infected Children Is an Indicator of Severe Disease with an Impaired Response to Antiretroviral Therapy. AIDS Research and Human Retroviruses. https://doi.org/10.1089/aid.2016.0261

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Napua, M., Pfeiffer, J. T., Chale, F., Hoek, R., Manuel, J., Michel, C., … Sherr, K. (2016). Option B+ in Mozambique: formative research findings for the design of a facility-level clustered randomized controlled trial to improve ART retention in antenatal care. J Acquir Immune Defic Syndr, 72. https://doi.org/10.1097/QAI.0000000000001061

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Oldenburg, C. E., Perez-Brumer, A. G., Reisner, S. L., Mayer, K. H., Mimiaga, M. J., Hatzenbuehler, M. L., & Bärnighausen, T. (2016). Human rights protections and HIV prevalence among MSM who sell sex: Cross-country comparisons from a systematic review and meta-analysis. Global Public Health, 1–12. https://doi.org/10.1080/17441692.2016.1149598

Ondenge, K., Renju, J., Bonnington, O., Moshabela, M., Wamoyi, J., Nyamukapa, C., … Skovdal, M. (2017). ‘I am treated well if I adhere to my HIV medication’: putting patient–provider interactions in context through insights from qualitative research in five sub-Saharan African countries. Sexually Transmitted Infections, 93(Suppl 3), e052973. https://doi.org/10.1136/sextrans-2016-052973

Orne-Gliemann, J., Zuma, T., Chikovore, J., Gillespie, N., Grant, M., Iwuji, C., … On Behalf of the TasP Study Group. (2016). Community perceptions of repeat HIV-testing: experiences of the ANRS 12249 Treatment as Prevention trial in rural South Africa. AIDS Care, 28(sup3), 14–23. https://doi.org/10.1080/09540121.2016.1164805

PANGEA_HIV Consortium, ICONIC Project, Yebra, G., Hodcroft, E. B., Ragonnet-Cronin, M. L., Pillay, D., … Kozlakidis, Z. (2016). Using nearly full-genome HIV sequence data improves phylogeny reconstruction in a simulated epidemic. Scientific Reports, 6(1). https://doi.org/10.1038/srep39489

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Surolia, R., Karki, S., Wang, Z., Kulkarni, T., Li, F. J., Vohra, S., … Antony, V. B. (2016). Attenuated heme oxygenase-1 responses predispose the elderly to pulmonary nontuberculous mycobacterial infections. American Journal of Physiology - Lung Cellular and Molecular Physiology, 311(5), L928–L940. https://doi.org/10.1152/ajplung.00397.2015

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Treffry-Goatley, A., Lessells, R., Sykes, P., Bärnighausen, T., de Oliveira, T., Moletsane, R., & Seeley, J. (2016). Understanding Specific Contexts of Antiretroviral Therapy Adherence in Rural South Africa: A Thematic Analysis of Digital Stories from a Community with High HIV Prevalence. PLOS ONE, 11(2), e0148801. https://doi.org/10.1371/journal.pone.0148801

 

van Rooyen, H., Essack, Z., Rochat, T., Wight, D., Knight, L., Bland, R., & Celum, C. (2016). Taking HIV Testing to Families: Designing a Family-Based Intervention to Facilitate HIV Testing, Disclosure, and Intergenerational Communication. Frontiers in Public Health, 4. https://doi.org/10.3389/fpubh.2016.00154

Vandormael, A. M., Boulware, D. R., Tanser, F. C., Bärnighausen, T. W., Stott, K. E., & de Oliveira, T. (2016). Brief Report: Virologic Monitoring Can Be a Cost-Effective Strategy to Diagnose Treatment Failure on First-Line ART. Journal of Acquired Immune Deficiency Syndromes (1999), 71(4), 462–466. https://doi.org/10.1097/QAI.0000000000000870

Wamoyi, J., Renju, J., Moshabela, M., McLean, E., Nyato, D., Mbata, D., … Wringe, A. (2017). Understanding the relationship between couple dynamics and engagement with HIV care services: insights from a qualitative study in Eastern and Southern Africa. Sexually Transmitted Infections, 93(Suppl 3). https://doi.org/10.1136/sextrans-2016-052976

Wang, H., Bhutta, Z. A., Coates, M. M., Coggeshall, M., Dandona, L., Diallo, K., … Murray, C. J. L. (2016). Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1725–1774. https://doi.org/10.1016/S0140-6736(16)31575-6

Wang, H., Naghavi, M., Allen, C., Barber, R. M., Bhutta, Z. A., Carter, A., … Murray, C. J. L. (2016). Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1459–1544. https://doi.org/10.1016/S0140-6736(16)31012-1

Wang, H., Wolock, T. M., Carter, A., Nguyen, G., Kyu, H. H., Gakidou, E., … Murray, C. J. L. (2016). Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980–2015: the Global Burden of Disease Study 2015. The Lancet HIV, 3(8), e361–e387. https://doi.org/10.1016/S2352-3018(16)30087-X

Watters, S. A., Mlcochova, P., Maldarelli, F., Goonetilleke, N., Pillay, D., & Gupta, R. K. (2016). Sequential CCR5-Tropic HIV-1 Reactivation from Distinct Cellular Reservoirs following Perturbation of Elite Control. PLOS ONE, 11(7), e0158854. https://doi.org/10.1371/journal.pone.0158854

White, E., Smit, E., Churchill, D., Collins, S., Booth, C., Tostevin, A., … Dunn, D. T. (2016). No Evidence That HIV-1 Subtype C Infection Compromises the Efficacy of Tenofovir-Containing Regimens: Cohort Study in the United Kingdom. Journal of Infectious Diseases, 214(9), 1302–1308. https://doi.org/10.1093/infdis/jiw213

Wringe, A., Moshabela, M., Nyamukapa, C., Bukenya, D., Ondenge, K., Ddaaki, W., … Renju, J. (2017). HIV testing experiences and their implications for patient engagement with HIV care and treatment on the eve of ‘test and treat’: findings from a multicountry qualitative study. Sexually Transmitted Infections, 93(Suppl 3), e052969. https://doi.org/10.1136/sextrans-2016-052969

 Yates, T. A., Tanser, F., & Abubakar, I. (2016). Plan Beta for tuberculosis: it’s time to think seriously about poorly ventilated congregate settings. The International Journal of Tuberculosis and Lung Disease, 20(1), 5–10. https://doi.org/10.5588/ijtld.15.0494

Zuma, T., Wight, D., Rochat, T., & Moshabela, M. (2016). The role of traditional health practitioners in Rural KwaZulu-Natal, South Africa: generic or mode specific? BMC Complementary and Alternative Medicine16(1). https://doi.org/10.1186/s12906-016-1293-8