Publications

2024 Publications

Adolph, C., Cheung, C.-Y., McNeil, M. B., Jowsey, W. J., Williams, Z. C., Hards, K., Harold, L. K., Aboelela, A., Bujaroski, R. S., Buckley, B. J., Tyndall, J. D. A., Li, Z., Langer, J. D., Preiss, L., Meier, T., Steyn, A. J. C., Rhee, K. Y., Berney, M., Kelso, M. J., & Cook, G. M. (2023). A dual-targeting succinate dehydrogenase and F1Fo-ATP synthase inhibitor rapidly sterilizes replicating and non-replicating Mycobacterium tuberculosis. Cell Chemical Biology, S2451945623004324. https://doi.org/10.1016/j.chembiol.2023.12.002

Ahmed, M., Tezera, L. B., Herbert, N., Chambers, M., Reichmann, M. T., Nargan, K., Kloverpris, H., Karim, F., Hlatshwayo, M., Madensein, R., Habesh, M., Hoque, M., Steyn, A. J. C., Elkington, P. T., & Leslie, A. J. (2024). Myeloid cell expression of CD200R is modulated in active TB disease and regulates Mycobacterium tuberculosis infection in a biomimetic model. Frontiers in Immunology, 15, 1360412. https://doi.org/10.3389/fimmu.2024.1360412

Auld, S. C., Barczak, A. K., Bishai, W., Coussens, A. K., Dewi, I. M. W., Mitini-Nkhoma, S. C., Muefong, C., Naidoo, T., Pooran, A., Stek, C., Steyn, A. J. C., Tezera, L., & Walker, N. F. (2024). Pathogenesis of Post-Tuberculosis Lung Disease: Defining Knowledge Gaps and Research Priorities at the 2nd International Post-Tuberculosis Symposium. American Journal of Respiratory and Critical Care Medicine, rccm.202402-0374SO. https://doi.org/10.1164/rccm.202402-0374SO

Bansi-Matharu, L., Revill, P., Taramusi, I., Steen, R., Chabata, S. T., Busza, J., Mangenah, C., Musemburi, S., Machingura, F., Desmond, N., Matambanadzo, P., Shahmanesh, M., Yekeye, R., Mugurungi, O., Cowan, F. M., Hargreaves, J. R., & Phillips, A. N. (2024). The effect on HIV transmission and cost-effectiveness of programmes for female sex workers in East, Central, and Southern Africa: A modelling study. The Lancet Global Health, 12(9), e1436–e1445. https://doi.org/10.1016/S2214-109X(24)00224-9

Banu, B., Khan, Md. M. H., Ali, L., Barnighausen, T., Sauerborn, R., & Souares, A. (2024). Pattern and predictors of non‐adherence to diabetes self‐management recommendations among patients in peripheral district of Bangladesh. Tropical Medicine & International Health, 29(3), 233–https://doi.org/10.1111/tmi.13966

Beattie, T. S., Adhiambo, W., Kabuti, R., Beksinska, A., Ngurukiri, P., Babu, H., Kung’u, M., Nyamweya, C., Mahero, A., Maisha Fiti Study -Champions, Irungu, E., Muthoga, P., Seeley, J., Kimani, J., Weiss, H. A., & Kaul, R. (2024). The epidemiology of HIV infection among female sex workers in Nairobi, Kenya: A structural determinants and life-course perspective. PLOS Global Public Health, 4(1), e0001529. https://doi.org/10.1371/journal.pgph.0001529

Berner-Rodoreda, A., Cobelens, F., Vandamme, A.-M., Froeschl, G., Skordis, J., Renganathan, E., t’Hoen, E., Raviglione, M., Jahn, A., & Bärnighausen, T. (2024). Transferable data exclusivity vouchers are not the solution to the antimicrobial drug development crisis: A commentary on the proposed EU pharma regulation. BMJ Global Health, 9(2), e014605. https://doi.org/10.1136/bmjgh-2023-014605

Brear, M. R., Manderson, L., Nkovana, T., & Harling, G. (2024). Conceptualisations of “good care” within informal caregiving networks for older people in rural South Africa. Social Science & Medicine, 344, 116597. https://doi.org/10.1016/j.socscimed.2024.116597

Brear, M. R., Manderson, L., Nkovana, T., & Harling, G. (2024). Conceptualisations of “good care” within informal caregiving networks for older people in rural South Africa. Social Science & Medicine, 344, 116597. https://doi.org/10.1016/j.socscimed.2024.116597

Buchholtz, N. V. E. J., Nühn, M. M., De Jong, T. C. M., Stienstra, T. A. T., Reddy, K., Ndung’u, T., Ndhlovu, Z. M., Fisher, K., Palmer, S., Wensing, A. M. J., Symons, J., & Nijhuis, M. (2024). Development of a highly sensitive and specific intact proviral DNA assay for HIV-1 subtype B and C. Virology Journal, 21(1), 36. https://doi.org/10.1186/s12985-024-02300-6

Bunker, A., Compoaré, G., Sewe, M. O., Laurent, J. G. C., Zabré, P., Boudo, V., Ouédraogo, W. A., Ouermi, L., Jackson, S. T., Arisco, N., Vijayakumar, G., Yildirim, F. B., Barteit, S., Maggioni, M. A., Woodward, A., Buonocore, J. J., Regassa, M. D., Brück, T., Sié, A., & Bärnighausen, T. (2024). The effects of cool roofs on health, environmental, and economic outcomes in rural Africa: Study protocol for a community-based cluster randomized controlled trial. Trials, 25(1), 59. https://doi.org/10.1186/s13063-023-07804-0

Calderwood, C. J., Marambire, E., Nzvere, F. P., Larsson, L. S., Chingono, R. M. S., Kavenga, F., Redzo, N., Bandason, T., Rusakaniko, S., Mujuru, H. A., Simms, V., Khan, P., Gregson, C. L., Ndhlovu, C. E., Ferrand, R. A., Fielding, K., & Kranzer, K. (2024). Prevalence of chronic conditions and multimorbidity among healthcare workers in Zimbabwe: Results from a screening intervention. PLOS Global Public Health, 4(1), e0002630. https://doi.org/10.1371/journal.pgph.0002630

Chimukuche, R. S., Kawuma, R., Nkosi, B., & Seeley, J. (2024). Scoping review on lessons learnt on the promotion and use of drugs and traditional medicine in Africa during COVID-19. Global Public Health, 19(1), 2323028. https://doi.org/10.1080/17441692.2024.2323028

Cowan, F. M., Machingura, F., Ali, M. S., Chabata, S. T., Takaruza, A., Dirawo, J., Makamba, M., Hove, T., Bansi-Matharu, L., Matambanadzo, P., Shahmanesh, M., Busza, J., Steen, R., Yekeye, R., Mpofu, A., Mugurungi, O., Phillips, A. N., & Hargreaves, J. R. (2024). A risk-differentiated, community-led intervention to strengthen uptake and engagement with HIV prevention and care cascades among female sex workers in Zimbabwe (AMETHIST): A cluster randomised trial. The Lancet Global Health, 12(9), e1424–e1435. https://doi.org/10.1016/S2214-109X(24)00235-3

Cuadros, D. F., Devi, C., Singh, U., Olivier, S., Castle, A. C., Moosa, Y., Edwards, J. A., Kim, H.-Y., Siedner, M. J., Wong, E. B., & Tanser, F. (2024). Convergence of HIV and non-communicable disease epidemics: Geospatial mapping of the unmet health needs in an HIV hyperendemic community in South Africa. BMJ Global Health, 9(1), e012730. https://doi.org/10.1136/bmjgh-2023-012730

Delphin, M., Mohammed, K. S., Downs, L. O., Lumley, S. F., Waddilove, E., Okanda, D., Aliyan, N., Van Schalkwyk, M., Anderson, M., Ocama, P., Maponga, T., Torimiro, J., Iwuji, C., Ndung’u, T., Matthews, P. C., & Taljaard, J. (2024). Under-representation of the WHO African region in clinical trials of interventions against hepatitis B virus infection. The Lancet Gastroenterology & Hepatology, S2468125323003151. https://doi.org/10.1016/S2468-1253(23)00315-1

Fernández Requena, B., Nadeem, S., Reddy, V. P., Naidoo, V., Glasgow, J. N., Steyn, A. J. C., Barbas, C., & Gonzalez-Riano, C. (2024). LiLA: Lipid lung-based ATLAS built through a comprehensive workflow designed for an accurate lipid annotation. Communications Biology, 7(1), 45. https://doi.org/10.1038/s42003-023-05680-7

Fwambah, L., Andisi, C., Streatfield, C., Bromell, R., Hare, J., Esbjörnsson, J., Ndung’u, T., Sanders, E. J., Hassan, A. S., & Nduati, E. (2024). Exposure to common infections may shape basal immunity and potentially HIV-1 acquisition amongst a high-risk population in Coastal Kenya. Frontiers in Immunology, 14, 1283559. https://doi.org/10.3389/fimmu.2023.1283559

Gärtner, K., Domínguez-Rodríguez, S., Heaney, J., Gkouleli, T., Grant, P., Dorgham, K., Sauce, D., Soulie, C., Busby, E. J., O’Sullivan, D. M., Spyer, M., Botha, J. C., Muñoz-Fernandez, M. A., Tagarro, A., Cotugno, N., Huggett, J. F., Klein, N., Palma, P., Rojo Conejo, P., … Nastouli, E. (2024). Low unspliced cell-associated HIV RNA in early treated adolescents living with HIV on long suppressive ART. Frontiers in Immunology, 15, 1334236. https://doi.org/10.3389/fimmu.2024.1334236

Ghalichi, L., Goodman-Palmer, D., Whitaker, J., Abio, A., Wilson, M. L., Wallis, L., Norov, B., Aryal, K. K., Malta, D. C., Bärnighausen, T., Geldsetzer, P., Flood, D., Vollmer, S., Theilmann, M., & Davies, J. (2024). Individual characteristics associated with road traffic collisions and healthcare seeking in low- and middle-income countries and territories. PLOS Global Public Health, 4(1), e0002768. https://doi.org/10.1371/journal.pgph.0002768

Houle, B., Kabudula, C., Mojola, S. A., Angotti, N., Gómez-Olivé, F. X., Gareta, D., Herbst, K., Clark, S. J., Menken, J., & Canudas-Romo, V. (2024). Mortality variability and differentials by age and causes of death in rural South Africa, 1994–2018. BMJ Global Health, 9(4), e013539. https://doi.org/10.1136/bmjgh-2023-013539

Jaumdally, S., Tomasicchio, M., Pooran, A., Esmail, A., Kotze, A., Meier, S., Wilson, L., Oelofse, S., Van Der Merwe, C., Roomaney, A., Davids, M., Suliman, T., Joseph, R., Perumal, T., Scott, A., Shaw, M., Preiser, W., Williamson, C., Goga, A., … Dheda, K. (2024). Frequency, kinetics and determinants of viable SARS-CoV-2 in bioaerosols from ambulatory COVID-19 patients infected with the Beta, Delta or Omicron variants. Nature Communications, 15(1), 2003. https://doi.org/10.1038/s41467-024-45400-1

Jaumdally, S., Tomasicchio, M., Pooran, A., Esmail, A., Kotze, A., Meier, S., Wilson, L., Oelofse, S., Van Der Merwe, C., Roomaney, A., Davids, M., Suliman, T., Joseph, R., Perumal, T., Scott, A., Shaw, M., Preiser, W., Williamson, C., Goga, A., … Dheda, K. (2024). Frequency, kinetics and determinants of viable SARS-CoV-2 in bioaerosols from ambulatory COVID-19 patients infected with the Beta, Delta or Omicron variants. Nature Communications, 15(1), 2003. https://doi.org/10.1038/s41467-024-45400-1

Jockers, D., Ngafuan, R., Baernighausen, T., Kessley, A., White, E. E., Kenny, A., Kraemer, J., Geedeh, J., Rozelle, J., Holmes, L., Obaje, H., Wheh, S., Pedersen, J., Siedner, M. J., Mendin, S., Subah, M., & Hirschhorn, L. R. (2024). Under-five mortality before and after implementation of the Liberia National Community Health Assistant (NCHA) program: A study protocol. PLOS ONE, 19(3), e0272172. https://doi.org/10.1371/journal.pone.0272172

Johnson, L. C. M., Khan, S. H., Ali, M. K., Galaviz, K. I., Waseem, F., Ordóñez, C. E., Siedner, M. J., Nyatela, A., Marconi, V. C., & Lalla-Edward, S. T. (2024). Understanding Barriers and Facilitators to Integrated HIV and Hypertension Care in South Africa [Preprint]. In Review. https://doi.org/10.21203/rs.3.rs-3885096/v1

Kean, I. R. L., Clark, J. A., Zhang, Z., Daubney, E., White, D., Ferrando-Vivas, P., Milla, G., Cuthbertson, B., Pappachan, J., Klein, N., Mouncey, P., Rowan, K., Myburgh, J., Gouliouris, T., Baker, S., Parkhill, J., Pathan, N., & Arctic Research Team. (2024). Short-duration selective decontamination of the digestive tract infection control does not contribute to increased antimicrobial resistance burden in a pilot cluster randomised trial (the ARCTIC Study). Gut, gutjnl-2023-330851. https://doi.org/10.1136/gutjnl-2023-330851

Khaba, T., Papadopoulos, A. O., Nkosi, T., Nxele, S., Ngubane, T., Jajbhay, I., Pansegrouw, J., & Ndhlovu, Z. M. (2024). Safety and practicality of an excisional lymph node study driving HIV cure research in South Africa. Frontiers in Immunology, 15, 1442556. https://doi.org/10.3389/fimmu.2024.1442556

Krause, R., Ogongo, P., Tezera, L., Ahmed, M., Mbano, I., Chambers, M., Ngoepe, A., Magnoumba, M., Muema, D., Karim, F., Khan, K., Lumamba, K., Nargan, K., Madansein, R., Steyn, A., Shalek, A. K., Elkington, P., & Leslie, A. (2024). B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and functional roles. Communications Biology, 7(1), 584. https://doi.org/10.1038/s42003-024-06282-7

Lee, K. S., Wolke, D., Bärnighausen, T., Ouermi, L., Bountogo, M., & Harling, G. (2024). Sexual victimisation, peer victimisation, and mental health outcomes among adolescents in Burkina Faso: A prospective cohort study. The Lancet Psychiatry, 11(2), 134–142. https://doi.org/10.1016/S2215-0366(23)00399-1

Li, Y., Choudhary, M. C., Regan, J., Boucau, J., Nathan, A., Speidel, T., Liew, M. Y., Edelstein, G. E., Kawano, Y., Uddin, R., Deo, R., Marino, C., Getz, M. A., Reynolds, Z., Barry, M., Gilbert, R. F., Tien, D., Sagar, S., Vyas, T. D., … Li, J.(2024) ZSARS-CoV-2 viral clearance and evolution varies by type and severity of immunodeficiency. Science Translational Medicine, 16(731), eadk1599. https://doi.org/10.1126/scitranslmed.adk1599

Lustig, G., Ganga, Y., Rodel, H. E., Tegally, H., Khairallah, A., Jackson, L., Cele, S., Khan, K., Jule, Z., Reedoy, K., Karim, F., Bernstein, M., Ndung’u, T., Moosa, M.-Y. S., Archary, D., De Oliveira, T., Lessells, R., Neher, R. A., Abdool Karim, S. S., & Sigal, A. (2024). SARS-CoV-2 infection in immunosuppression evolves sub-lineages which independently accumulate neutralization escape mutations. Virus Evolution, 10(1), vead075. https://doi.org/10.1093/ve/vead075

Mahlalela, N. B., Manne-Goehler, J., Ohene-Kwofie, D., B. Adams, L., Montana, L., Kahn, K., Rohr, J. K., Bärnighausen, T., & Gómez-Olivé, F. X. (2024). The Association Between HIV-Related Stigma and the Uptake of HIV Testing and ART Among Older Adults in Rural South Africa: Findings from the HAALSI Cohort Study. AIDS and Behavior. https://doi.org/10.1007/s10461-023-04222-w

Manne-Goehler, J., & Siedner, M. J. (2024). Untangling the causal ties between antiretrovirals and obesity. The Lancet HIV, S2352301824002145. https://doi.org/10.1016/S2352-3018(24)00214-5

Mpofana, N., Yalo, M., Gqaleni, N., Dlova, N. C., & Hussein, A. A. (2023). Analysis of Three Species of Cassipourea Traditionally Used for Hypermelanosis in Selected Provinces in South Africa. International Journal of Molecular Sciences, 25(1), 237. https://doi.org/10.3390/ijms25010237

Mussa, A., Jarolimova, J., Ryan, R., Wynn, A., Ashour, D., Bassett, I. V., Philpotts, L. L., Freyne, B., Morroni, C., & Dugdale, C. M. (2024). Syphilis prevalence among people living with and without HIV in sub-Saharan Africa: A systematic review and meta-analysis. Sexually Transmitted Diseases. https://doi.org/10.1097/OLQ.0000000000001920

Myers, B., Regenauer, K. S., Rose, A., Johnson, K., Ndamase, S., Ciya, N., Brown, I., Joska, J., Bassett, I. V., Belus, J. M., Ma, T., Sibeko, G., & Magidson, J. F. (2024). Community health worker training to reduce mental health and substance use stigma towards patients who have disengaged from HIV/TB care in South Africa: Protocol for a stepped wedge hybrid type II pilot implementation trial. Implementation Science Communications, 5(1), 1. https://doi.org/10.1186/s43058-023-00537-w

Nanyonjo, G., Kwena, Z., Nakamanya, S., Okello, E., Oketch, B., Bahemuka, U. M., Ssetaala, A., Okech, B., Price, M. A., Kapiga, S., Fast, P., Bukusi, E., Seeley, J., & the LVCHR study team. (2024). Finding women in fishing communities around Lake Victoria: “Feasibility and acceptability of using phones and tracking devices”. PLOS ONE, 19(1), e0290634. https://doi.org/10.1371/journal.pone.0290634

Ng’uni, T. L., Musale, V., Nkosi, T., Mandolo, J., Mvula, M., Michelo, C., Karim, F., Moosa, M. Y. S., Khan, K., Jambo, K. C., Hanekom, W., Sigal, A., Kilembe, W., & Ndhlovu, Z. M. (2024). Low pre-existing endemic human coronavirus (HCoV-NL63)-specific T cell frequencies are associated with impaired SARS-CoV-2-specific T cell responses in people living with HIV. Frontiers in Immunology, 14, 1291048. https://doi.org/10.3389/fimmu.2023.1291048

Ngwenya, N., Dziva Chikwari, C., Seeley, J., & Ferrand, R. A. (2023). Are concepts of adolescence from the Global North appropriate for Africa? A debate. BMJ Global Health, 8(12), e012614. https://doi.org/10.1136/bmjgh-2023-012614

Ngwenya, N., Smith, T., Shahmanesh, M., Psaros, C., Munikwa, C., Nkosi, K., & Seeley, J. (2024). Social Categorisation and Social Identification: The Mediating Role of Social Isolation and Loneliness in Adolescents Living with HIV. International Journal of Behavioral Medicine, 31(3), 459–467. https://doi.org/10.1007/s12529-023-10205-x

Nimmo, C., Ortiz, A. T., Tan, C. C. S., Pang, J., Acman, M., Millard, J., Padayatchi, N., Grant, A. D., O’Donnell, M., Pym, A., Brynildsrud, O. B., Eldholm, V., Grandjean, L., Didelot, X., Balloux, F., & Van Dorp, L. (2024). Detection of a historic reservoir of bedaquiline/clofazimine resistance-associated variants in Mycobacterium tuberculosis. Genome Medicine, 16(1), 34. https://doi.org/10.1186/s13073-024-01289-5

Olmo-Fontánez, A. M., Scordo, J. M., Schami, A., Garcia-Vilanova, A., Pino, P. A., Hicks, A., Mishra, R., Jose Maselli, D., Peters, J. I., Restrepo, B. I., Nargan, K., Naidoo, T., Clemens, D. L., Steyn, A. J. C., Thacker, V. V., Turner, J., Schlesinger, L. S., & Torrelles, J. B. (2024). Human alveolar lining fluid from the elderly promotes Mycobacterium tuberculosis intracellular growth and translocation into the cytosol of alveolar epithelial cells. Mucosal Immunology, 17(2), 155–168. https://doi.org/10.1016/j.mucimm.2024.01.001

Olmo-Fontánez, A. M., Scordo, J. M., Schami, A., Garcia-Vilanova, A., Pino, P. A., Hicks, A., Mishra, R., Jose Maselli, D., Peters, J. I., Restrepo, B. I., Nargan, K., Naidoo, T., Clemens, D. L., Steyn, A. J. C., Thacker, V. V., Turner, J., Schlesinger, L. S., & Torrelles, J. B. (2024). Human alveolar lining fluid from the elderly promotes Mycobacterium tuberculosis intracellular growth and translocation into the cytosol of alveolar epithelial cells. Mucosal Immunology, S1933021924000011. https://doi.org/10.1016/j.mucimm.2024.01.001

Phelps, N. H., Singleton, R. K., Zhou, B., Heap, R. A., Mishra, A., Bennett, J. E., Paciorek, C. J., Lhoste, V. P., Carrillo-Larco, R. M., Stevens, G. A., Rodriguez-Martinez, A., Bixby, H., Bentham, J., Di Cesare, M., Danaei, G., Rayner, A. W., Barradas-Pires, A., Cowan, M. J., Savin, S., … Ezzati, M. (2024). Worldwide trends in underweight and obesity from 1990 to 2022: A pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults. The Lancet, S0140673623027502. https://doi.org/10.1016/S0140-6736(23)02750-2

Quach, L. T., Ritchie, C. S., Reynolds, Z., Paul, R., Seeley, J., Tong, Y., Hoeppner, S., Okello, S., Nakasujja, N., Olivieri-Mui, B., Saylor, D., Greene, M., Asiimwe, S., Tindimwebwa, E., Atwiine, F., Sentongo, R., Siedner, M. J., & Tsai, A. C. (2024). HIV, Social Networks, and Loneliness among Older Adults in Uganda. AIDS and Behavior. https://doi.org/10.1007/s10461-023-04258-y

Ramsay, M., Crampin, A. C., Bawah, A. A., Gitau, E., & Herbst, K. (2024). The value proposition of coordinated population cohorts across Africa. Annual Review of Biomedical Data Science, 7(1), 277–294. https://doi.org/10.1146/annurev-biodatasci-020722-015026

Rapulana, A. M., Mpotje, T., Baiyegunhi, O. O., Ndlovu, H., Smit, T. K., McHugh, T. D., & Marakalala, M. J. (2024). Combined analysis of host IFN-γ, IL-2 and IP-10 as potential LTBI biomarkers in ESAT-6/CFP-10 stimulated blood. Frontiers in Molecular Medicine, 4, 1345510. https://doi.org/10.3389/fmmed.2024.1345510

Renedo, D., Acosta, J. N., Leasure, A. C., Sharma, R., Krumholz, H. M., De Havenon, A., Alahdab, F., Aravkin, A. Y., Aryan, Z., Bärnighausen, T. W., Basu, S., Burkart, K., Coberly, K., Criqui, M. H., Dai, X., Desai, R., Dharmaratne, S. D., Doshi, R., Elgendy, I. Y., … Sheth, K. N. (2024). Burden of Ischemic and Hemorrhagic Stroke Across the US From 1990 to 2019. JAMA Neurology. https://doi.org/10.1001/jamaneurol.2024.0190

Riou, C., Bhiman, J. N., Ganga, Y., Sawry, S., Ayres, F., Baguma, R., Balla, S. R., Benede, N., Bernstein, M., Besethi, A. S., Cele, S., Crowther, C., Dhar, M., Geyer, S., Gill, K., Grifoni, A., Hermanus, T., Kaldine, H., Keeton, R. S., … Fairlie, L. (2024). Safety and immunogenicity of booster vaccination and fractional dosing with Ad26.COV2.S or BNT162b2 in Ad26.COV2.S-vaccinated participants. PLOS Global Public Health, 4(4), e0002703. https://doi.org/10.1371/journal.pgph.0002703

Rohr, J. K., Huber-Krum, S., Rugarabamu, A., Pearson, E., Francis, J. M., Guo, M., Siril, H., Shah, I., Canning, D., Ulenga, N., & Bärnighausen, T. W. (2024). Impact of a post-partum family planning intervention on contraception and fertility in Tanzania: Two-year follow-up of a cluster-randomised controlled trial. The European Journal of Contraception & Reproductive Health Care, 29(1), 24–31. https://doi.org/10.1080/13625187.2023.2290985

Samuels, V., Mulelu, A. E., Ndlovu, H., & Marakalala, M. J. (2024). Mycobacterial FtsEX-RipC interaction is required for normal growth and cell morphology in rifampicin and low ionic strength conditions. Microbiology Spectrum, 12(3), e02515-23. https://doi.org/10.1128/spectrum.02515-23

Samuels, V., Mulelu, A. E., Ndlovu, H., & Marakalala, M. J. (2024). Mycobacterial FtsEX-RipC interaction is required for normal growth and cell morphology in rifampicin and low ionic strength conditions. Microbiology Spectrum, e02515-23. https://doi.org/10.1128/spectrum.02515-23

Samuels, V., Mulelu, A. E., Ndlovu, H., & Marakalala, M. J. (2024). Mycobacterial FtsEX-RipC interaction is required for normal growth and cell morphology in rifampicin and low ionic strength conditions. Microbiology Spectrum, 12(3), e02515-23. https://doi.org/10.1128/spectrum.02515-23

Samuels, V., Mulelu, A. E., Ndlovu, H., & Marakalala, M. J. (2024). Mycobacterial FtsEX-RipC interaction is required for normal growth and cell morphology in rifampicin and low ionic strength conditions. Microbiology Spectrum, e02515-23. https://doi.org/10.1128/spectrum.02515-23

Ssali, A., Nabaggala, G., Mubiru, M. C., Semakula, I., Seeley, J., & King, R. (2023). Contextual, structural, and mental health experiences of children of women engaged in high-risk sexual behaviour in Kampala: A mixed method study. Frontiers in Public Health, 11, 1185339. https://doi.org/10.3389/fpubh.2023.1185339

Stein, D. T., Reitsma, M. B., Geldsetzer, P., Agoudavi, K., Aryal, K. K., Bahendeka, S., Brant, L. C. C., Farzadfar, F., Gurung, M. S., Guwatudde, D., Houehanou, Y. C. N., Malta, D. C., Martins, J. S., Saeedi Moghaddam, S., Mwangi, K. J., Norov, B., Sturua, L., Zhumadilov, Z., Bärnighausen, T., … Verguet, S. (2024). Hypertension care cascades and reducing inequities in cardiovascular disease in low- and middle-income countries. Nature Medicine. https://doi.org/10.1038/s41591-023-02769-8

The CRyPTIC Consortium, Barilar, I., Battaglia, S., Borroni, E., Brandao, A. P., Brankin, A., Cabibbe, A. M., Carter, J., Chetty, D., Cirillo, D. M., Claxton, P., Clifton, D. A., Cohen, T., Coronel, J., Crook, D. W., Dreyer, V., Earle, S. G., Escuyer, V., Ferrazoli, L., … Zhu, B. (2024). Quantitative measurement of antibiotic resistance in Mycobacterium tuberculosis reveals genetic determinants of resistance and susceptibility in a target gene approach. Nature Communications, 15(1), 488. https://doi.org/10.1038/s41467-023-44325-5

Tomasicchio, M., Jaumdally, S., Wilson, L., Kotze, A., Semple, L., Meier, S., Pooran, A., Esmail, A., Pillay, K., Roberts, R., Kriel, R., Meldau, R., Oelofse, S., Mandviwala, C., Burns, J., Londt, R., Davids, M., Van Der Merwe, C., Roomaney, A., … Dheda, K. (2024). SARS-CoV-2 Viral Replication Persists in the Human Lung for Several Weeks after Symptom Onset. American Journal of Respiratory and Critical Care Medicine, rccm.202308-1438OC. https://doi.org/10.1164/rccm.202308-1438OC

White, R. G., Fiore-Gartland, A. J., Hanekom, W. A., Vekemans, J., Garcia-Basteiro, A. L., Churchyard, G., Rangaka, M. X., Frick, M., Behr, M. A., Hill, P. C., & Mave, V. (2024). What is next for BCG revaccination to prevent tuberculosis? The Lancet Respiratory Medicine, 12(3), e7–e8. https://doi.org/10.1016/S2213-2600(24)00009-2

White, R. G., Fiore-Gartland, A. J., Hanekom, W. A., Vekemans, J., Garcia-Basteiro, A. L., Churchyard, G., Rangaka, M. X., Frick, M., Behr, M. A., Hill, P. C., & Mave, V. (2024). What is next for BCG revaccination to prevent tuberculosis? The Lancet Respiratory Medicine, 12(3), e7–e8. https://doi.org/10.1016/S2213-2600(24)00009-2

Zhu, M., Frank, M. W., Radka, C. D., Jeanfavre, S., Tse, M. W., Pacheco, J. A., Pierce, K., Deik, A., Xu, J., Hussain, S., Hussain, F. A., Xulu, N., Khan, N., Pillay, V., Dong, K. L., Ndung’u, T., Clish, C. B., Rock, C. O., Blainey, P. C., … Kwon, D. S. (2023). Vaginal Lactobacillus fatty acid response mechanisms reveal a novel strategy for bacterial vaginosis treatment [Preprint]. Microbiology. https://doi.org/10.1101/2023.12.30.573720

2023 Publications

Abdullahi, A., Kida, I. M., Maina, U. A., Ibrahim, A. H., Mshelia, J., Wisso, H., Adamu, A., Onyemata, J. E., Edun, M., Yusuph, H., Aliyu, S. H., Charurat, M., Abimiku, A., Abeler-Dorner, L., Fraser, C., Bonsall, D., PANGEA consortium, Abeler-Dörner, L., Ayles, H., … Gupta, R. K. (2023). Limited emergence of resistance to integrase strand transfer inhibitors (INSTIs) in ART-experienced participants failing dolutegravir-based antiretroviral therapy: A cross-sectional analysis of a Northeast Nigerian cohort. Journal of Antimicrobial Chemotherapy, dkad195. https://doi.org/10.1093/jac/dkad195

Adriano Vieira, V., Lim, N., Singh, A., Leitman, E., D’Souza, R. R., Adland, E., Muenchhoff, M., Roider, J., Marín Lopez, M. Á., Carabelli, J., Giandhari, J., Groll, A., Jooste, P., Prado, J. G., Thobakgale, C., Dong, K., Kiepiela, P., Prendergast, A. J., Tudor-Williams, G., Thumbi Ndung'u., Alasdair Leslie, Henrik N Kløverpris., … Goulder, P. (2023). Paediatric HIV slow-progression is associated with early CD8+ T-cell PD-1 expression and a stem-like phenotype. JCI Insight. https://doi.org/10.1172/jci.insight.156049

Allué-Guardia, A., Torrelles, J. B., & Sigal, A. (2023). Tuberculosis and COVID-19 in the elderly: Factors driving a higher burden of disease. Frontiers in Immunology, 14, 1250198. https://doi.org/10.3389/fimmu.2023.1250198

Busang, J., Zuma, T., Herbst, C., Okesola, N., Chimbindi, N., Dreyer, J., Mtshali, N., Smit, T., Ngubane, S., Hlongwane, S., Gumede, D., Jalazi, A., Mdluli, S., Bird, K., Msane, S., Danisa, P., Hanekom, W., Lebina, L., Behuhuma, N., … Shahmanesh, M. (2023). Thetha Nami ngithethe nawe (Let’s Talk): A stepped-wedge cluster randomised trial of social mobilisation by peer navigators into community-based sexual health and HIV care, including pre-exposure prophylaxis (PrEP), to reduce sexually transmissible HIV amongst young people in rural KwaZulu-Natal, South Africa. BMC Public Health, 23(1), 1553. https://doi.org/10.1186/s12889-023-16262-x

Busisiwe, N., Seeley, J., Strode, A., & Parker, M. (2023). Beyond translations, perspectives for researchers to consider to enhance comprehension during consent processes for health research in sub-saharan Africa: A scoping review. BMC Medical Ethics, 24(1), 43. https://doi.org/10.1186/s12910-023-00920-1

Castle, A. C., Hoeppner, S. S., Magodoro, I. M., Singh, U., Moosa, Y., Bassett, I. V., Wong, E. B., Siedner, M. J., & on behalf of the Vukuzazi Study Team. (2023). Association between prior tuberculosis disease and dysglycemia within an HIV-endemic, rural South African population. PLOS ONE, 18(3), e0282371. https://doi.org/10.1371/journal.pone.0282371

Castle, A. C., Hoeppner, S. S., Manne-Goehler, J. M., Olivier, S., Magodoro, I. M., Singh, U., Edwards, J. A., Tanser, F., Bassett, I. V., Wong, E. B., Siedner, M. J., & on behalf of the Vukuzazi Study Team. (2023). Identifying sex-specific anthropometric measures and thresholds for dysglycemia screening in an HIV-endemic rural South African population. PLOS Global Public Health, 3(10), e0001698. https://doi.org/10.1371/journal.pgph.0001698

Chidumwa, G., Olivier, S., Ngubane, H., Zulu, T., Sewpaul, R., Kruse, G., Rigotti, N. A., Siedner, M. J., Reddy, K. P., & Wong, E. B. (2023). Tobacco smoking and prevalence of communicable and non-communicable diseases in rural South Africa: A cross-sectional study [Preprint]. In Review. https://doi.org/10.21203/rs.3.rs-2730894/v1

Cuadros, D. F., Devi, C., Singh, U., Olivier, S., Castle, A., Moosa, Y., Edwards, J. A., Kim, H.-Y., Siedner, M. J., Wong, E. B., & Tanser, F. (2023). Convergence of HIV and non-communicable disease epidemics: Geospatial mapping of the unmet health needs in a HIV Hyperendemic South African community [Preprint]. Epidemiology. https://doi.org/10.1101/2023.03.27.23287807

Cuadros, D. F., Moreno, C. M., Tomita, A., Singh, U., Olivier, S., Castle, A., Moosa, Y., Edwards, J. A., Kim, H.-Y., Siedner, M. J., Wong, E. B., & Tanser, F. (2023). Geospatial assessment of the convergence of communicable and non-communicable diseases in South Africa. Journal of Multimorbidity and Comorbidity, 13, 26335565231204119. https://doi.org/10.1177/26335565231204119

DeSanto, D., Velen, K., Lessells, R., Makgopa, S., Gumede, D., Fielding, K., Grant, A. D., Charalambous, S., & Chetty-Makkan, C. M. (2023). A qualitative exploration into the presence of TB stigmatization across three districts in South Africa. BMC Public Health, 23(1), 504. https://doi.org/10.1186/s12889-023-15407-2

Fehr, J., Gunda, R., Siedner, M. J., Hanekom, W., Ndung´u, T., Grant, A., Lippert, C., & Wong, E. B. (2023). CAD4TB software updates: Different triaging thresholds require caution by users and regulation by authorities. The International Journal of Tuberculosis and Lung Disease, 27(2), 157–160. https://doi.org/10.5588/ijtld.22.0437

Gibbs, A., Gumede, D., Adeagbo, O., Sikweyiya, Y., Chirwa, E., Mkhwanazi, S., Luthuli, M., Xulu, Z., Herbst, C., Zuma, T., Hlongwane, S., Okesola, N., Dreyer, J., Khaula, S., Washington, L., & Shahmanesh, M. (2023). Adaptation and pre-test of a shortened Stepping Stones and Creating Futures intervention focused on HIV for young men in rural South Africa. PLOS Global Public Health, 3(2), e0001632. https://doi.org/10.1371/journal.pgph.0001632

Greuel, M., Sy, F., Bärnighausen, T., Adam, M., Vandormael, A., Gates, J., & Harling, G. (2023). Community Health Worker Use of Smart Devices for Health Promotion: Scoping Review. JMIR MHealth and UHealth, 11, e42023. https://doi.org/10.2196/42023

Haribhai, S., Bhatia, K., & Shahmanesh, M. (2023). Global elective breast- and colorectal cancer surgery performance backlogs, attributable mortality and implemented health system responses during the COVID-19 pandemic: A scoping review. PLOS Global Public Health, 3(4), e0001413. https://doi.org/10.1371/journal.pgph.0001413

Houle, B., Kabudula, C., Gareta, D., Herbst, K., & Clark, S. J. (2023). Household structure, composition and child mortality in the unfolding antiretroviral therapy era in rural South Africa: Comparative evidence from population surveillance, 2000–2015. BMJ Open, 13(3), e070388. https://doi.org/10.1136/bmjopen-2022-070388

Hwa, S.-H., Snyman, J., Bernstein, M., Ganga, Y., Cele, S., Muema, D., Tan, C. W., Khan, K., Karim, F., Hanekom, W., Bernstein, L., Kaufmann, S. H. E., Wang, L.-F., Ndung’u, T., Sigal, A., the COMMIT-KZN Team, Steyn, A., Leslie, A., Ramjit, D., … Ndhlovu, Z. (2023). Association Between Human Immunodeficiency Virus Viremia and Compromised Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2 Beta Variant. The Journal of Infectious Diseases, 227(2), 211–220. https://doi.org/10.1093/infdis/jiac343

Hysenaj, L., Little, S., Kulhanek, K., Magnen, M., Bahl, K., Gbenedio, O. M., Prinz, M., Rodriguez, L., Andersen, C., Rao, A. A., Shen, A., Lone, J.-C., Lupin-Jimenez, L. C., Bonser, L. R., Serwas, N. K., Mick, E., Khalid, M. M., Taha, T. Y., Kumar, R., … Roose, J. P. (2023). SARS-CoV-2 infection of airway organoids reveals conserved use of Tetraspanin-8 by Ancestral, Delta, and Omicron variants. Stem Cell Reports, S2213671123000140. https://doi.org/10.1016/j.stemcr.2023.01.011

Jeewanraj, N., Mandizvo, T., Mulaudzi, T., Gumede, N., Ndhlovu, Z., Ndung’u, T., Gounder, K., & Mann, J. (2023). Partial compartmentalisation of HIV-1 subtype C between lymph nodes, peripheral blood mononuclear cells and plasma. Virology, 582, 62–70. https://doi.org/10.1016/j.virol.2023.03.011

Kasprowicz, V. O., Jeffery, C., Mbuvi, D., Bukirwa, V., Ouattara, K., Kirimi, F., Heitz-Tokpa, K., Gorrethy, M., Chopera, D., Nakanjako, D., Bonfoh, B., Elliott, A., Kinyanjui, S., Bates, I., & Ndung’u, T. (2023). How to improve research capacity strengthening efforts: Learning from the monitoring and evaluation of four research consortia in Africa. Health Research Policy and Systems, 21(1), 109. https://doi.org/10.1186/s12961-023-01056-9

Keter, A. K., Lynen, L., Van Heerden, A., Wong, E., Reither, K., Goetghebeur, E., & Jacobs, B. K. M. (2023). Evaluation of tuberculosis diagnostic test accuracy using Bayesian latent class analysis in the presence of conditional dependence between the diagnostic tests used in a community-based tuberculosis screening study. PLOS ONE, 18(3), e0282417. https://doi.org/10.1371/journal.pone.0282417

Krause, R. G. E., Moyo-Gwete, T., Richardson, S. I., Makhado, Z., Manamela, N. P., Hermanus, T., Mkhize, N. N., Keeton, R., Benede, N., Mennen, M., Skelem, S., Karim, F., Khan, K., Riou, C., Ntusi, N. A. B., Goga, A., Gray, G., Hanekom, W., Garrett, N., … Leslie, A. (2023). Infection pre-Ad26.COV2.S-vaccination primes greater class switching and reduced CXCR5 expression by SARS-CoV-2-specific memory B cells. Npj Vaccines, 8(1), 119. https://doi.org/10.1038/s41541-023-00724-9

Le Roux, S. R., Jassat, W., Dickson, L., Mitrani, L., Cox, H., Mlisana, K., Black, J., Loveday, M., Grant, A. D., Moshabela, M., Kielmann, K., & Nicol, M. P. (2022). The role of emergent champions in policy implementation for decentralised drug-resistant tuberculosis care in South Africa. BMJ Global Health, 7(12), e008907. https://doi.org/10.1136/bmjgh-2022-008907

Luthuli, B., Gounder, K., Deymier, M. J., Dong, K. L., Balazs, A. B., Mann, J. K., & Ndung’u, T. (2023). Generation and characterization of infectious molecular clones of transmitted/founder HIV-1 subtype C viruses. Virology, 583, 14–26. https://doi.org/10.1016/j.virol.2023.04.001

Mabweazara, S., Manne-Goehler, J., Hamer, M., Cellini, J., & Siedner, M. (2023). Characteristics and efficacy of physical activity interventions to improve cardiometabolic and psychosocial outcomes in people living with HIV in sub-Saharan Africa: A protocol for a systematic review. Systematic Reviews, 12(1), 24. https://doi.org/10.1186/s13643-023-02186-5

Mabweazara, S., Manne-Goehler, J., Hamer, M., Cellini, J., & Siedner, M. (2023). Characteristics and efficacy of physical activity interventions to improve cardiometabolic and psychosocial outcomes in people living with HIV in sub-Saharan Africa: A protocol for a systematic review. Systematic Reviews, 12(1), 24. https://doi.org/10.1186/s13643-023-02186-5

Madela, S., Harriman, N., Sewpaul, R., Mbewu, A., Williams, D., Sifunda, S., Manyaapelo, T., Nyembezi, A., & Reddy, S. (2023). Individual and area-level socioeconomic correlates of hypertension prevalence, awareness, treatment, and control in uMgungundlovu, KwaZulu-Natal, South Africa. BMC Public Health, 23(1), 417. https://doi.org/10.1186/s12889-023-15247-0

Madlala, P., Mkhize, Z., Naicker, S., Khathi, S. P., Maikoo, S., Gopee, K., Dong, K. L., & Ndung’u, T. (2023). Genetic variation of the HIV-1 subtype C transmitted/founder viruses long terminal repeat elements and the impact on transcription activation potential and clinical disease outcomes. PLOS Pathogens, 19(6), e1011194. https://doi.org/10.1371/journal.ppat.1011194

Makofane, K., Kim, H., Tchetgen Tchetgen, E., Bassett, M. T., Berkman, L., Adeagbo, O., McGrath, N., Seeley, J., Shahmanesh, M., Yapa, H. M., Herbst, K., Tanser, F., & Bärnighausen, T. (2023). Impact of family networks on uptake of health interventions: Evidence from a community‐randomized control trial aimed at increasing HIV testing in South Africa. Journal of the International AIDS Society, 26(8), e26142. https://doi.org/10.1002/jia2.26142

Moyano, A., Ndlovu, B., Mbele, M., Naidoo, K., Khan, N., Mann, J. K., & Ndung’u, T. (2023). Differing natural killer cell, T cell and antibody profiles in antiretroviral-naive HIV-1 viraemic controllers with and without protective HLA alleles. PLOS ONE, 18(6), e0286507. https://doi.org/10.1371/journal.pone.0286507

Moyano, A., Ndlovu, B., Mbele, M., Naidoo, K., Khan, N., Mann, J. K., & Ndung’u, T. (2023). Differing natural killer cell, T cell and antibody profiles in antiretroviral-naive HIV-1 viraemic controllers with and without protective HLA alleles. PLOS ONE, 18(6), e0286507. https://doi.org/10.1371/journal.pone.0286507

Mpotje, T., More, J., Rajkumar-Bhugeloo, K., Moodley, D., & Marakalala, M. J. (2023). Validation of proteins associated with pathological damage in human tuberculosis granulomas: Study protocol. Wellcome Open Research, 8, 139. https://doi.org/10.12688/wellcomeopenres.19226.1

Mthembu, M., Bowman, K. A., Davies, L. R. L., Khuzwayo, S., Mazibuko, L., Bassett, T., Ramjit, D., Mhlane, Z., Karim, F., Alter, G., Ndung’u, T., & Wong, E. B. (2023). Discrepancy between Mtb-specific IFN-γ and IgG responses in HIV-positive people with low CD4 counts. EBioMedicine, 90, 104504. https://doi.org/10.1016/j.ebiom.2023.104504

Mthiyane, N., Rapulana, A. M., Harling, G., Copas, A., & Shahmanesh, M. (2023). Effect of multi-level interventions on mental health outcomes among adolescents in sub-Saharan Africa: A systematic review. BMJ Open, 13(10), e066586. https://doi.org/10.1136/bmjopen-2022-066586

Mukora, R., Thompson, R. R., Hippner, P., Pelusa, R., Mothibi, M., Lessells, R., Grant, A. D., Fielding, K., Velen, K., Charalambous, S., Dowdy, D. W., & Sohn, H. (2023). Human resource time commitments and associated costs of Community Caregiver outreach team operations in South Africa. PLOS ONE, 18(3), e0282425. https://doi.org/10.1371/journal.pone.0282425

Musvosvi, M., Huang, H., Wang, C., Xia, Q., Rozot, V., Krishnan, A., Acs, P., Cheruku, A., Obermoser, G., Leslie, A., Behar, S. M., Hanekom, W. A., Bilek, N., Fisher, M., Kaufmann, S. H. E., Walzl, G., Hatherill, M., Davis, M. M., Scriba, T. J., … Van, T. (2023). T cell receptor repertoires associated with control and disease progression following Mycobacterium tuberculosis infection. Nature Medicine. https://doi.org/10.1038/s41591-022-02110-9

Naidoo, K. K., Highton, A. J., Baiyegunhi, O. O., Bhengu, S. P., Dong, K. L., Bunders, M. J., Altfeld, M., & Ndung’u, T. (2023). Early initiation of antiretroviral therapy preserves the metabolic function of CD4+ T-cells in subtype C HIV-1 infection. The Journal of Infectious Diseases, jiad432. https://doi.org/10.1093/infdis/jiad432

Nascimento, F. F., Ragonnet-Cronin, M., Golubchik, T., Danaviah, S., Derache, A., Fraser, C., & Volz, E. (2022). Evaluating whole HIV-1 genome sequence for estimation of incidence and migration in a rural South African community. Wellcome Open Research, 7, 174. https://doi.org/10.12688/wellcomeopenres.17891.1

Ndung’u, T. (2023). Fighting HIV where it matters most. Nature Microbiology, 8(10), 1751–1753. https://doi.org/10.1038/s41564-023-01463-2

Ndung’u, T. (2023). The KT Jeang retrovirology prize 2023: Thumbi Ndung’u. Retrovirology, 20(1), 17, s12977-023-00632–00639. https://doi.org/10.1186/s12977-023-00632-9

Nelson, K. N., Churchyard, G., Cobelens, F., Hanekom, W. A., Hill, P. C., Lopman, B., Mave, V., Rangaka, M. X., Vekemans, J., White, R. G., Wong, E. B., Martinez, L., & García-Basteiro, A. L. (2023). Measuring indirect transmission-reducing effects in tuberculosis vaccine efficacy trials: Why and how? The Lancet Microbe, S266652472300112X. https://doi.org/10.1016/S2666-5247(23)00112-X

Nguyen, A. N., Plotkin, A. L., Odumade, O. A., De Armas, L., Pahwa, S., Morrocchi, E., Cotugno, N., Rossi, P., Foster, C., Domínguez-Rodríguez, S., Tagarro, A., Syphurs, C., Diray-Arce, J., Fatou, B., Ozonoff, A., Levy, O., Palma, P., Smolen, K. K., on the behalf of the EPIICAL Consortium, … Kityo, C. (2023). Effective early antiretroviral therapy in perinatal-HIV infection reduces subsequent plasma inflammatory profile. Pediatric Research. https://doi.org/10.1038/s41390-023-02669-0

Plazy, M., Diallo, A., Hlabisa, T., Okesola, N., Iwuji, C., Herbst, K., Boyer, S., Lert, F., McGrath, N., Pillay, D., Dabis, F., Larmarange, J., Orne-Gliemann, J., & for the ANRS TasP Study Group. (2023). Implementation and effectiveness of a linkage to HIV care intervention in rural South Africa (ANRS 12249 TasP trial). PLOS ONE, 18(1), e0280479. https://doi.org/10.1371/journal.pone.0280479

Randera-Rees, S., Clarence Safari, W., Gareta, D., Herbst, K., Baisley, K., & Grant, A. D. (2023). Can we find the missing men in clinics? Clinic attendance by sex and HIV status in rural South Africa. Wellcome Open Research, 6, 169. https://doi.org/10.12688/wellcomeopenres.16702.2

Roest, J., Nkosi, B., Seeley, J., Molyneux, S., & Kelley, M. (2023). Respecting relational agency in the context of vulnerability: What can research ethics learn from the social sciences? Bioethics, bioe.13139. https://doi.org/10.1111/bioe.13139

Shinde, S., Noor, R. A., Mwanyika‐Sando, M., Moshabela, M., Tadesse, A. W., Sherfi, H., Vandormael, A., Young, T., Tinkasimile, A., Drysdale, R., Baernighausen, T., Sharma, D., & Fawzi, W. W. (2023). Adolescent health and well‐being in sub‐Saharan Africa: Strengthening knowledge base and research capacity through a collaborative multi‐country school‐based study. Maternal & Child Nutrition, e13411. https://doi.org/10.1111/mcn.13411

Sigal, A. (2023). Boosting in the age of Omicron. ELife, 12, e87358. https://doi.org/10.7554/eLife.87358

Singh, U., Olivier, S., Cuadros, D., Castle, A., Moosa, Y., Edwards, J. A., Kim, H.-Y., Siedner, M. J., Tanser, F., & Wong, E. B. (2023). Quantifying met and unmet health needs for HIV, hypertension and diabetes in rural KwaZulu-Natal, South Africa [Preprint]. In Review. https://doi.org/10.21203/rs.3.rs-2702048/v1

Singh, U., Olivier, S., Cuadros, D., Castle, A., Moosa, Y., Zulu, T., Edwards, J. A., Kim, H.-Y., Gunda, R., Koole, O., Surujdeen, A., Gareta, D., Munatsi, D., Modise, T. H., Dreyer, J., Nxumalo, S., Smit, T. K., Ordering-Jespersen, G., Mpofana, I. B., … Harilall, S. (2023). The met and unmet health needs for HIV, hypertension, and diabetes in rural KwaZulu-Natal, South Africa: Analysis of a cross-sectional multimorbidity survey. The Lancet Global Health, 11(9), e1372–e1382. https://doi.org/10.1016/S2214-109X(23)00239-5

Sithole, N., Castle, A., Nxumalo, S., Mazibuko, L., Manyaapelo, T., Abrahams-Gessel, S., Dlamini, S., Gareta, D., Orne-Gliemann, J., Baisley, K., Bachmann, M., Magula, N., Gaziano, T. A., & Siedner, M. J. (2023). Protocol: Implementation evaluation of a combination intervention for sustainable blood pressure control in rural KwaZulu-Natal, South Africa (IMPACT BP): A three-arm, unblinded, parallel group individually randomized clinical trial. Contemporary Clinical Trials, 131, 107258. https://doi.org/10.1016/j.cct.2023.107258

Smith, J., Bansi-Matharu, L., Cambiano, V., Dimitrov, D., Bershteyn, A., van de Vijver, D., Kripke, K., Revill, P., Boily, M.-C., Meyer-Rath, G., Taramusi, I., Lundgren, J. D., van Oosterhout, J. J., Kuritzkes, D., Schaefer, R., Siedner, M. J., Schapiro, J., Delany-Moretlwe, S., Landovitz, R. J., … Phillips, A. N. (2023). Predicted effects of the introduction of long-acting injectable cabotegravir pre-exposure prophylaxis in sub-Saharan Africa: A modelling study. The Lancet HIV, S2352301822003654. https://doi.org/10.1016/S2352-3018(22)00365-4

Turkova, A., White, E., Kekitiinwa, A. R., Mumbiro, V., Kaudha, E., Liberty, A., Ahimbisibwe, G. M., Moloantoa, T., Srirompotong, U., Mosia, N. R., Puthanakit, T., Kobbe, R., Fortuny, C., Kataike, H., Bbuye, D., Na-Rajsima, S., Coelho, A., Lugemwa, A., Bwakura-Dangarembizi, M. F., … Zuidewind, P. (2023). Neuropsychiatric manifestations and sleep disturbances with dolutegravir-based antiretroviral therapy versus standard of care in children and adolescents: A secondary analysis of the ODYSSEY trial. The Lancet Child & Adolescent Health, S2352464223001645. https://doi.org/10.1016/S2352-4642(23)00164-5

Vieira, V., Lim, N., Singh, A., Leitman, E., Dsouza, R., Adland, E., Muenchhoff, M., Roider, J., Marin Lopez, M., Carabelli, J., Giandhari, J., Groll, A., Jooste, P., Prado, J. G., Thobakgale, C., Dong, K., Kiepiela, P., Prendergast, A. J., Tudor-Williams, G., … Goulder, P. (2023). Slow progression of pediatric HIV associates with early CD8+ T cell PD-1 expression and a stem-like phenotype. JCI Insight, 8(3), e156049. https://doi.org/10.1172/jci.insight.156049

2022 Publications

Edwards, A., Mahomed-Asmail, F., Olivier, A.-M., van der Linde, J., Khoza-Shangase, K., Moroe, N., & Neille, J. (2022). In pursuit of best practice through contextually relevant, accountable and responsive research. South African Journal of Communication Disorders, 69(1). https://doi.org/10.4102/sajcd.v69i1.945

Adeagbo, O. A., Seeley, J., Gumede, D., Xulu, S., Dlamini, N., Luthuli, M., Dreyer, J., Herbst, C., Cowan, F., Chimbindi, N., Hatzold, K., Okesola, N., Johnson, C., Harling, G., Subedar, H., Sherr, L., McGrath, N., Corbett, L., & Shahmanesh, M. (2022). Process evaluation of peer-to-peer delivery of HIV self-testing and sexual health information to support HIV prevention among youth in rural KwaZulu-Natal, South Africa: Qualitative analysis. BMJ Open, 12(2), e048780. https://doi.org/10.1136/bmjopen-2021-048780

Ahmed, M., Mackenzie, J., Tezera, L., Krause, R., Truebody, B., Garay-Baquero, D., Vallejo, A., Govender, K., Adamson, J., Fisher, H., Essex, J. W., Mansour, S., Elkington, P., Steyn, A. J. C., & Leslie, A. (2022).Mycobacterium tuberculosis senses host Interferon-γ via the membrane protein MmpL10. Communications Biology, 5(1), 1317. https://doi.org/10.1038/s42003-022-04265-0

Ahmed, M., Mackenzie, J., Tezera, L., Krause, R., Truebody, B., Garay-Baquero, D., Vallejo, A., Govender, K., Adamson, J., Fisher, H., Essex, J. W., Mansour, S., Elkington, P., Steyn, A. J. C., & Leslie, A. (2022). Mycobacterium tuberculosis senses host Interferon-γ via the membrane protein MmpL10. Communications Biology, 5(1), 1317. https://doi.org/10.1038/s42003-022-04265-0

Amuge, P., Lugemwa, A., Wynne, B., Mujuru, H. A., Violari, A., Kityo, C. M., Archary, M., Variava, E., White, E., Turner, R. M., Shakeshaft, C., Ali, S., Nathoo, K. J., Atwine, L., Liberty, A., Bbuye, D., Kaudha, E., Mngqibisa, R., Mosala, M., … Zuidewind, P. (2022). Once-daily dolutegravir-based antiretroviral therapy in infants and children living with HIV from age 4 weeks: Results from the below 14 kg cohort in the randomised ODYSSEY trial. The Lancet HIV, 9(9), e638–e648. https://doi.org/10.1016/S2352-3018(22)00163-1

Arsenault, C., Gage, A., Kim, M. K., Kapoor, N. R., Akweongo, P., Amponsah, F., Aryal, A., Asai, D., Awoonor-Williams, J. K., Ayele, W., Bedregal, P., Doubova, S. V., Dulal, M., Gadeka, D. D., Gordon-Strachan, G., Mariam, D. H., Hensman, D., Joseph, J. P., Kaewkamjornchai, P., … Kruk, M. E. (2022). Covid-19 and resilience of healthcare systems in ten countries. Nature Medicine, 28(6), 1314–1324. https://doi.org/10.1038/s41591-022-01750-1

Baisley, K., Orne‐Gliemann, J., Larmarange, J., Plazy, M., Collier, D., Dreyer, J., Mngomezulu, T., Herbst, K., Hanekom, W., Dabis, F., Siedner, M. J., & Iwuji, C. (2022). Early HIV treatment and survival over six years of observation in the ANRS 12249 Treatment as Prevention Trial. HIV Medicine, hiv.13263. https://doi.org/10.1111/hiv.13263

Baiyegunhi, O. O., Mann, J., Khaba, T., Nkosi, T., Mbatha, A., Ogunshola, F., Chasara, C., Ismail, N., Ngubane, T., Jajbhay, I., Pansegrouw, J., Dong, K. L., Walker, B. D., Ndung’u, T., & Ndhlovu, Z. M. (2022). CD8 lymphocytes mitigate HIV-1 persistence in lymph node follicular helper T cells during hyperacute-treated infection. Nature Communications, 13(1), 4041. https://doi.org/10.1038/s41467-022-31692-8

Bengu, N., Mchunu, N., Mokhethi, S., Fillis, R., Cromhout, G., Lobenstein, J. van, Graza, Y., Kapongo, C., Chinniah, K., Bhoola, R., Adland, E., Puertas, M. C., Ndung’u, T., Martinez-Picado, J., Archary, M., & Goulder, P. J. R. (2022). Next-generation point-of-care testing in pediatric human immunodeficiency virus infection facilitates diagnosis and monitoring of treatment. Medicine, 101(27), e29228. https://doi.org/10.1097/MD.0000000000029228

Bernabe, K. J., Siedner, M., Tsai, A. C., Marconi, V. C., & Murphy, R. A. (2022). Detection of HIV virologic failure and switch to second-line therapy: A systematic review and meta-analysis of data from sub-Saharan Africa. Open Forum Infectious Diseases, ofac121. https://doi.org/10.1093/ofid/ofac121

Boeke, C. E., Khan, S., Walsh, F. J., Lejeune, C., Hettema, A., Spiegelman, D., Okello, V., & Bärnighausen, T. (2021). Longitudinal analysis of client appointment adherence under Universal Test and Treat strategy: A stepped‐wedge trial. HIV Medicine, 22(9), 854–859. https://doi.org/10.1111/hiv.13144

Bogart, L. M., Shazi, Z., MacCarthy, S., Mendoza-Graf, A., Wara, N. J., Zionts, D., Dube, N., Govere, S., & Bassett, I. V. (2022). Implementation of South Africa’s Central Chronic Medicine Dispensing and Distribution Program for HIV Treatment: A Qualitative Evaluation. AIDS and Behavior, 26(8), 2600–2612. https://doi.org/10.1007/s10461-022-03602-y

Bousmah, M.-Q., Iwuji, C., Okesola, N., Orne-Gliemann, J., Pillay, D., Dabis, F., Larmarange, J., & Boyer, S. (2022). Costs and economies of scale in repeated home-based HIV counselling and testing: Evidence from the ANRS 12249 treatment as prevention trial in South Africa. Social Science & Medicine, 305, 115068. https://doi.org/10.1016/j.socscimed.2022.115068

Cele, S., Karim, F., Lustig, G., San, J. E., Hermanus, T., Tegally, H., Snyman, J., Moyo-Gwete, T., Wilkinson, E., Bernstein, M., Khan, K., Hwa, S.-H., Tilles, S. W., Singh, L., Giandhari, J., Mthabela, N., Mazibuko, M., Ganga, Y., Gosnell, B. I., Karim SA, Hanekom W, Van Voorhis WC, Ndungâ U T; COMMIT-KZN Team, Lessells RJ, Moore PL, Moosa MS, de Oliveira T, Sigal A. (2022). SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escape. Cell Host & Microbe, S1931312822000415. https://doi.org/10.1016/j.chom.2022.01.005

Chidumwa, G., Chimbindi, N., Herbst, C., Okeselo, N., Dreyer, J., Zuma, T., Smith, T., Molina, J.-M., Khoza, T., McGrath, N., Seeley, J., Pillay, D., Tanser, F., Harling, G., Sherr, L., Copas, A., Baisley, K., & Shahmanesh, M. (2022). Isisekelo Sempilo study protocol for the effectiveness of HIV prevention embedded in sexual health with or without peer navigator support (Thetha Nami) to reduce prevalence of transmissible HIV amongst adolescents and young adults in rural KwaZulu-Natal: A 2 × 2 factorial randomised controlled trial. BMC Public Health, 22(1), 454. https://doi.org/10.1186/s12889-022-12796-8

Chimbindi, N., & Shahmanesh, M. (2022). PrEP dispensing with HIV self-testing. The Lancet HIV, 9(7), e450–e451. https://doi.org/10.1016/S2352-3018(22)00171-0

Chimukuche, R. S., Kawuma, R., Mahapa, N., Mkhwanazi, S., Singh, N., Siva, S., Ruzagira, E., Seeley, J., On behalf of the PrEPVacc Study Group, Gray, G., Singh, N., Gaffoor, Z., Morar, N., Sithole, T., Woeber, K., Siva, S., Hwengwere, E., Chidawanyika, R. S., Mahapa, N., … Robb, M. (2022). Examining oral pre-exposure prophylaxis (PrEP) literacy among participants in an HIV vaccine trial preparedness cohort study. BMC Health Services Research, 22(1), 1336. https://doi.org/10.1186/s12913-022-08730-8

Chimukuche, R. S., Nkosi, B., & Seeley, J. (2022). Policy and Guideline Review of Vaccine Safety for COVID-19 in Pregnant Women in Southern Africa, with a Particular Focus on South Africa. Vaccines, 10(12), 2077. https://doi.org/10.3390/vaccines10122077

Chimukuche, R., Ngwenya, N., Seeley, J., Nxumalo, P., Nxumalo, Z., Godongwana, M., Radebe, N., Myburgh, N., Adedini, S., & Cutland, C. (2022). Assessing Community Acceptance of Maternal Immunisation in Rural KwaZulu-Natal, South Africa: A Qualitative Investigation. Vaccines, 10(3), 415. https://doi.org/10.3390/vaccines10030415

Cowan, F. M., Machingura, F., Chabata, S. T., Ali, M. S., Busza, J., Steen, R., Desmond, N., Shahmanesh, M., Revill, P., Mpofu, A., Yekeye, R., Mugurungi, O., Phillips, A. N., & Hargreaves, J. R. (2022). Differentiated prevention and care to reduce the risk of HIV acquisition and transmission among female sex workers in Zimbabwe: Study protocol for the ‘AMETHIST’ cluster randomised trial. Trials, 23(1), 209. https://doi.org/10.1186/s13063-022-06119-w

Dzomba, A., Kim, H.-Y., Tomita, A., Vandormael, A., Govender, K., & Tanser, F. (2022). Predictors of migration in an HIV hyper-endemic rural South African community: Evidence from a population-based cohort (2005–2017). BMC Public Health, 22(1), 1141. https://doi.org/10.1186/s12889-022-13526-w

Fardoos, R., Nyquist, S. K., Asowata, O. E., Kazer, S. W., Singh, A., Ngoepe, A., Giandhari, J., Mthabela, N., Ramjit, D., Singh, S., Karim, F., Buus, S., Anderson, F., Porterfield, J. Z., Sibiya, A. L., Bipath, R., Moodley, K., Kuhn, W., Berger, B., … Kløverpris, H. N. (2022). HIV specific CD8+ TRM-like cells in tonsils express exhaustive signatures in the absence of natural HIV control. Frontiers in Immunology, 13, 912038. https://doi.org/10.3389/fimmu.2022.912038

Fentress, M., Henwood, P. C., Maharaj, P., Mitha, M., Khan, D., Caligiuri, P., Karat, A. S., Olivier, S., Edwards, A., Ramjit, D., Ngcobo, N., Wong, E. B., & Grant, A. D. (2022). High sensitivity of ultrasound for the diagnosis of tuberculosis in adults in South Africa: A proof-of-concept study. PLOS Global Public Health, 2(10), e0000800. https://journals.plos.org/globalpublichealth/article?id=10.1371/journal.pgph.0000800

Fentress, M., Henwood, P. C., Maharaj, P., Mitha, M., Khan, D., Jackpersad, R., Pitcher, R., Redfern, A., Lopez Varela, E., van der Zalm, M. M., Wong, E. B., Palmer, M., & Grant, A. D. (2022). Thoracic ultrasound for TB diagnosis in adults and children. Public health action, 12(1), 3–6. https://doi.org/10.5588/pha.21.0072

Fernández-Luis, S., Lain, M. G., Serna-Pascual, M., Domínguez-Rodríguez, S., Kuhn, L., Liberty, A., Barnabas, S., Lopez-Varela, E., Otwombe, K., Danaviah, S., Nastouli, E., Palma, P., Cotugno, N., Spyer, M., Giannuzzi, V., Giaquinto, C., Violari, A., Cotton, M. F., Nhampossa, T., Klein, N., Behuhuma, O., Goulder, P … Maiga, A. (2022). Optimizing the World Health Organization algorithm for HIV vertical transmission risk assessment by adding maternal self-reported antiretroviral therapy adherence. BMC Public Health, 22(1), 1312. https://doi.org/10.1186/s12889-022-13543-9

Fisher, K. L., Moodley, D., Rajkumar-Bhugeloo, K., Baiyegunhi, O. O., Karim, F., Ndlovu, H., Ndung’u, T., & Marakalala, M. J. (2022). Elevated IP-10 at the protein and gene level associates with pulmonary TB. Frontiers in Cellular and Infection Microbiology, 12, 908144. https://doi.org/10.3389/fcimb.2022.908144

Floyd, S., Mulwa, S., Magut, F., Gourlay, A., Mthiyane, N., Kamire, V., Osindo, J., Otieno, M., Chimbindi, N., Ziraba, A., Phillips-Howard, P., Kwaro, D., Shahmanesh, M., & Birdthistle, I. (2022). DREAMS impact on HIV status knowledge and sexual risk among cohorts of young women in Kenya and South Africa. AIDS, 36(Supplement 1), S61–S73. https://doi.org/10.1097/QAD.0000000000003157

Gibbs, A., Desmond, C., Barnett, T., Shahmanesh, M., & Seeley, J. (2022). Is hope associated with HIV-acquisition risk and intimate partner violence amongst young women and men? A cross-sectional study in urban informal settlements in South Africa. AIDS Care, 1–8. https://doi.org/10.1080/09540121.2022.2143470

Gibbs, J., Solomon, D., Jackson, L., Mullick, S., Burns, F., & Shahmanesh, M. (2022). Measuring and evaluating sexual health in the era of digital health: Challenges and opportunities. Sexual Health. https://doi.org/10.1071/SH22068

Gideon, H. P., Hughes, T. K., Tzouanas, C. N., Wadsworth, M. H., Tu, A. A., Gierahn, T. M., … Leslie, A., Behar, S.M., Bryson, B., Flynn, J.L., Fortune, S.M., Shalek, A. K. (2022). Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control. Immunity, S1074761322001753. https://doi.org/10.1016/j.immuni.2022.04.004

Gourlay, A. J., Birdthistle, I., Mulwa, S., Mthiyane, N. T., Magut, F., Chimbindi, N., Ziraba, A., Otieno, M., Kwaro, D., Osindo, J., Kamire, V., Shahmanesh, M., & Floyd, S. (2022). Awareness and uptake of the Determined, Resilient, Empowered, AIDS-free, Mentored and Safe HIV prevention package over time among population-based cohorts of young women in Kenya and South Africa. AIDS, 36(Supplement 1), S27–S38. https://doi.org/10.1097/QAD.0000000000003120

Gourlay, A., Floyd, S., Magut, F., Mulwa, S., Mthiyane, N., Wambiya, E., Otieno, M., Kamire, V., Osindo, J., Chimbindi, N., Ziraba, A., Kwaro, D., Shahmanesh, M., & Birdthistle, I. (2022). Impact of the DREAMS Partnership on social support and general self-efficacy among adolescent girls and young women: Causal analysis of population-based cohorts in Kenya and South Africa. BMJ Global Health, 7(3), e006965. https://doi.org/10.1136/bmjgh-2021-006965

Govere-Hwenje, S., Jarolimova, J., Yan, J., Khumalo, A., Zondi, G., Ngcobo, M., Wara, N. J., Zionts, D., Bogart, L. M., Parker, R. A., & Bassett, I. V. (2022). Willingness to accept Covid-19 vaccination among people living with HIV in a high HIV prevalence community. BMC Public Health, 22(1), 1239. https://doi.org/10.1186/s12889-022-13623-w

Greaney, A. J., Eguia, R. T., Starr, T. N., Khan, K., Franko, N., Logue, J. K., Lord, S. M., Speake, C., Chu, H. Y., Sigal, A., & Bloom, J. D. (2022). The SARS-CoV-2 Delta variant induces an antibody response largely focused on class 1 and 2 antibody epitopes. PLOS Pathogens, 18(6), e1010592. https://doi.org/10.1371/journal.ppat.1010592

Greaney, A. J., Starr, T. N., Eguia, R. T., Loes, A. N., Khan, K., Karim, F., Cele, S., Bowen, J. E., Logue, J. K., Corti, D., Veesler, D., Chu, H. Y., Sigal, A., & Bloom, J. D. (2022). A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy. PLOS Pathogens, 18(2), e1010248. https://doi.org/10.1371/journal.ppat.1010248

Gumede, D., Meyer-Weitz, A., Zuma, T., Shahmanesh, M., & Seeley, J. (2022). A qualitative investigation of facilitators and barriers to DREAMS uptake among adolescents with grandparent caregivers in rural KwaZulu-Natal, South Africa. PLOS Global Public Health, 2(9), e0000369. https://doi.org/10.1371/journal.pgph.0000369

Inghels, M., Kim, H.-Y., Mathenjwa, T., Shahmanesh, M., Seeley, J., Wyke, S., McGrath, N., Sartorius, B., Yapa, H. M., Dobra, A., Bärnighausen, T., & Tanser, F. (2022). Can a conditional financial incentive (CFI) reduce socio-demographic inequalities in home-based HIV testing uptake? A secondary analysis of the HITS clinical trial intervention in rural South Africa. Social Science & Medicine, 311, 115305. https://doi.org/10.1016/j.socscimed.2022.115305

Iwuji, C., Pillay, D., Shamu, P., Murire, M., Nzenze, S., Cox, L.-A., & Mullick, S. (2022). A systematic review of antimicrobial resistance in Neisseria gonorrhoeae and Mycoplasma genitalium in sub-Saharan Africa. Journal of Antimicrobial Chemotherapy, dkac159. https://doi.org/10.1093/jac/dkac159

Jahagirdar, D., Walters, M. K., Novotney, A., Brewer, E. D., Frank, T. D., Carter, A., Biehl, M. H., Abbastabar, H., Abhilash, E. S., Abu-Gharbieh, E., Abu-Raddad, L. J., Adekanmbi, V., Adeyinka, D. A., Adnani, Q. E. S., Afzal, S., Aghababaei, S., Ahinkorah, B. O., Ahmad, S., Ahmadi, K., … Kyu, H. H. (2021). Global, regional, and national sex-specific burden and control of the HIV epidemic, 1990–2019, for 204 countries and territories: The Global Burden of Diseases Study 2019. The Lancet HIV, 8(10), e633–e651. https://doi.org/10.1016/S2352-3018(21)00152-1

Jarolimova, J., Platt, L. R., Curtis, M. R., Philpotts, L. L., Bekker, L.-G., Morroni, C., Shahmanesh, M., Mussa, A., Barracks, K., Ciaranello, A. L., Parker, R. A., Bassett, I. V., & Dugdale, C. M. (2022). Curable sexually transmitted infections among women with HIV in sub-Saharan Africa. AIDS, 36(5), 697–709. https://doi.org/10.1097/QAD.0000000000003163

Kampiire, L., Archary, M., Frigati, L., Penazatto, M., & Brusamento, S. (2022). Immunization for Children Living With HIV: A Scoping Review. Journal of the Pediatric Infectious Diseases Society, piab119. https://doi.org/10.1093/jpids/piab119

Keeton, R., Tincho, M. B., Ngomti, A., Baguma, R., Benede, N., Suzuki, A., Khan, K., Cele, S., Bernstein, M., Karim, F., Madzorera, S. V., Moyo-Gwete, T., Mennen, M., Skelem, S., Adriaanse, M., Mutithu, D., Aremu, O., Stek, C., du Bruyn, E., … Riou, C. (2022). T cell responses to SARS-CoV-2 spike cross-recognize Omicron. Nature. https://doi.org/10.1038/s41586-022-04460-3

Kemp, S. A., Charles, O. J., Derache, A., Smidt, W., Martin, D. P., Iwuji, C., Adamson, J., Govender, K., de Oliveira, T., Dabis, F., Pillay, D., Goldstein, R. A., & Gupta, R. K. (2022). HIV-1 Evolutionary Dynamics under Nonsuppressive Antiretroviral Therapy. MBio, e00269-22. https://doi.org/10.1128/mbio.00269-22

Khan, K., Karim, F., Cele, S., Reedoy, K., San, J. E., Lustig, G., Tegally, H., Rosenberg, Y., Bernstein, M., Jule, Z., Ganga, Y., Ngcobo, N., Mazibuko, M., Mthabela, N., Mhlane, Z., Mbatha, N., Miya, Y., Giandhari, J., Ramphal, Y., … Sigal, A. (2022). Omicron infection enhances Delta antibody immunity in vaccinated persons. Nature. https://doi.org/10.1038/s41586-022-04830-x

Khan, K., Lustig, G., Bernstein, M., Archary, D., Cele, S., Karim, F., Smith, M., Ganga, Y., Jule, Z., Reedoy, K., Miya, Y., Mthabela, N., Magula, N. P., Lessells, R., de Oliveira, T., Gosnell, B. I., Abdool Karim, S., Garrett, N., Hanekom, W., … Ndhlovu, Z. (2022). Immunogenicity of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Ad26.CoV2.S Vaccination in People Living With Human Immunodeficiency Virus (HIV). Clinical Infectious Diseases, 75(1), e857–e864. https://doi.org/10.1093/cid/ciab1008

Kim, H.-Y., Cuadros, D., Wilkinson, E., Junqueira, D. M., Oliveira, T. de, & Tanser, F. (2022). The geography and inter-community configuration of new sexual partnership formation in a rural South African population over fourteen years (2003–2016). PLOS Global Public Health, 2(3), e0000055. https://doi.org/10.1371/journal.pgph.0000055

Kruse, G., Zulu, T., Ngubane, H., Reddy, K., Siedner, M., Rigotti, N. A., Seeley, J., Ngwenya, N., & Wong, E. (2022). The ethics of conducting observational tobacco research without providing treatment to people who use tobacco: A case example from South Africa. BMJ Global Health, 7(7), e009732. https://doi.org/10.1136/bmjgh-2022-009732

Lustig, G., Ganga, Y., Rodel, H., Tegally, H., Jackson, L., Cele, S., Khan, K., Jule, Z., Reedoy, K., Karim, F., Bernstein, M., Moosa, M.-Y. S., Archary, D., de Oliveira, T., Lessells, R., Abdool Karim, S. S., & Sigal, A. (2022). SARS-CoV-2 evolves increased infection elicited cell death and fusion in an immunosuppressed individual [Preprint]. Infectious Diseases (except HIV/AIDS). https://doi.org/10.1101/2022.11.23.22282673

Lustig, G., Ganga, Y., Rodel, H., Tegally, H., Jackson, L., Cele, S., Khan, K., Jule, Z., Reedoy, K., Karim, F., Bernstein, M., Moosa, M.-Y. S., Archary, D., de Oliveira, T., Lessells, R., Abdool Karim, S. S., & Sigal, A. (2022). SARS-CoV-2 evolves increased infection elicited cell death and fusion in an immunosuppressed individual [Preprint]. Infectious Diseases (except HIV/AIDS). https://doi.org/10.1101/2022.11.23.22282673

Luthuli, M., Ngwenya, N., Gumede, D., Gunda, R., Gareta, D., Koole, O., Siedner, M. J., Wong, E. B., & Seeley, J. (2022). Participant recall and understandings of information on biobanking and future genomic research: Experiences from a multi-disease community-based health screening and biobank platform in rural South Africa. BMC Medical Ethics, 23(1), 43. https://doi.org/10.1186/s12910-022-00782-z

Mahlobo, B., Laher, F., Smidt, W., Ogunshola, F., Khaba, T., Nkosi, T., Mbatha, A., Ngubane, T., Dong, K., Jajbhay, I., Pansegrouw, J., & Ndhlovu, Z. M. (2022). The impact of HIV infection on the frequencies, function, spatial localization and heterogeneity of T follicular regulatory cells (TFRs) within human lymph nodes. BMC Immunology, 23(1), 34. https://doi.org/10.1186/s12865-022-00508-1

Mandizvo, T., Gumede, N., Ndlovu, B., Ndlovu, S., Mann, J. K., Chopera, D. R., Singh, L., Dong, K. L., Walker, B. D., Ndhlovu, Z. M., Lavine, C. L., Seaman, M. S., Gounder, K., & Ndung’u, T. (2022). Subtle Longitudinal Alterations in Env Sequence Potentiate Differences in Sensitivity to Broadly Neutralizing Antibodies following Acute HIV-1 Subtype C Infection. Journal of Virology, e01270-22. https://doi.org/10.1128/jvi.01270-22

Marcus, M. E., Manne-Goehler, J., Theilmann, M., Farzadfar, F., Moghaddam, S. S., Keykhaei, M., Hajebi, A., Tschida, S., Lemp, J. M., Aryal, K. K., Dunn, M., Houehanou, C., Bahendeka, S., Rohloff, P., Atun, R., Bärnighausen, T. W., Geldsetzer, P., Ramirez-Zea, M., Chopra, V., … Flood, D. (2022). Use of statins for the prevention of cardiovascular disease in 41 low-income and middle-income countries: A cross-sectional study of nationally representative, individual-level data. The Lancet Global Health, 10(3), e369–e379. https://doi.org/10.1016/S2214-109X(21)00551-9

Martin, D. P., Lytras, S., Lucaci, A. G., Maier, W., Grüning, B., Shank, S. D., Weaver, S., MacLean, O. A., Orton, R. J., Lemey, P., Boni, M. F., Tegally, H., Harkins, G. W., Scheepers, C., Bhiman, J. N., Everatt, J., Amoako, D. G., San, J. E., Giandhari, J., … Kosakovsky Pond, S. L. (2022). Selection analysis identifies clusters of unusual mutational changes in Omicron lineage BA.1 that likely impact Spike function. Molecular Biology and Evolution, msac061. https://doi.org/10.1093/molbev/msac061

Matimba, A., Ali, S., Littler, K., Madden, E., Marshall, P., McCurdy, S., Nembaware, V., Rodriguez, L., Seeley, J., Tindana, P., Yakubu, A., & de Vries, J. (2022). Guideline for feedback of individual genetic research findings for genomics research in Africa. BMJ Global Health, 7(1), e007184. https://doi.org/10.1136/bmjgh-2021-007184

McCaffrey, E. F., Donato, M., Keren, L., Chen, Z., Delmastro, A., Fitzpatrick, M. B., Gupta, S., Greenwald, N. F., Baranski, A., Graf, W., Kumar, R., Bosse, M., Fullaway, C. C., Ramdial, P. K., Forgó, E., Jojic, V., Van Valen, D., Mehra, S., Khader, S. A., Bendall SC, van de Rijn M, Kalman D, Kaushal D, Hunter RL, Banaei N, Steyn AJC, Khatri P, Angelo M. (2022). The immunoregulatory landscape of human tuberculosis granulomas. Nature Immunology. https://doi.org/10.1038/s41590-021-01121-x

McCreesh, N., Karat, A. S., Govender, I., Baisley, K., Diaconu, K., Yates, T. A., Houben, R. M., Kielmann, K., Grant, A. D., & White, R. (2022). Estimating the contribution of transmission in primary healthcare clinics to community-wide TB disease incidence, and the impact of infection prevention and control interventions, in KwaZulu-Natal, South Africa. BMJ Global Health, 7(4), e007136. https://doi.org/10.1136/bmjgh-2021-007136

McCreesh, N., Mohlamonyane, M., Edwards, A., Olivier, S., Dikgale, K., Dayi, N., Gareta, D., Wood, R., Grant, A. D., White, R. G., & Middelkoop, K. (2022). Improving Estimates of Social Contact Patterns for Airborne Transmission of Respiratory Pathogens. Emerging Infectious Diseases, 28(10), 2016–2026. https://doi.org/10.3201/eid2810.212567

Meng, B., Abdullahi, A., Ferreira, I. A. T. M., Goonawardane, N., Saito, A., Kimura, I., Yamasoba, D., Gerber, P. P., Fatihi, S., Rathore, S., Zepeda, S. K., Papa, G., Kemp, S. A., Ikeda, T., Toyoda, M., Tan, T. S., Kuramochi, J., Mitsunaga, S., Ueno, T., … Gupta, R. K. (2022). Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts tropism and fusogenicity. Nature. https://doi.org/10.1038/s41586-022-04474-x

Miall, A., McLellan, R., Dong, K., Ndung’u, T., Saberi, P., Sauceda, J. A., & Dubé, K. (2022). Bringing social context into global biomedical HIV cure-related research: An urgent call to action. Journal of Virus Eradication, 8(1), 100062. https://doi.org/10.1016/j.jve.2021.100062

Millar, J. R., Bengu, N., Vieira, V. A., Adland, E., Roider, J., Muenchhoff, M., Fillis, R., Sprenger, K., Ntlantsana, V., Fatti, I., Archary, M., Groll, A., Ismail, N., García-Guerrero, M. C., Matthews, P. C., Ndung’u, T., Puertas, M. C., Martinez-Picado, J., & Goulder, P. (2021). Early initiation of antiretroviral therapy following in utero HIV infection is associated with low viral reservoirs but other factors determine viral rebound. The Journal of Infectious Diseases, 224(11), 1925–1934. https://doi.org/10.1093/infdis/jiab223

Moyano, A., Ndungu, T., & Mann, J. K. (2022). Determinants of natural HIV-1 control. Aids Reviews, 0(0), 7765. https://doi.org/10.24875/AIDSRev.21000048

Mthiyane, N., Baisley, K., Chimbindi, N., Zuma, T., Okesola, N., Dreyer, J., Herbst, C., Smit, T., Danaviah, S., McGrath, N., Harling, G., Sherr, L., Seeley, J., Floyd, S., Birdthistle, I., & Shahmanesh, M. (2022). The association of exposure to DREAMS on sexually acquiring or transmitting HIV amongst adolescent girls and young women living in rural South Africa. AIDS, 36(Supplement 1), S39–S49. https://doi.org/10.1097/QAD.0000000000003156

Mvaya, L., Khaba, T., Lakudzala, A. E., Nkosi, T., Jambo, N., Kadwala, I., Kankwatira, A., Patel, P. D., Gordon, M. A., Nyirenda, T. S., Jambo, K. C., & Ndhlovu, Z. M. (2022). Differential localization and limited cytotoxic potential of duodenal CD8+ T cells. JCI Insight, 7(3), e154195. https://doi.org/10.1172/jci.insight.154195

Nachega, J. B., Sam-Agudu, N. A., Machekano, R. N., Rabie, H., van der Zalm, M. M., Redfern, A., Dramowski, A., O’Connell, N., Pipo, M. T., Tshilanda, M. B., Byamungu, L. N., Masekela, R., Jeena, P. M., Pillay, A., Gachuno, O. W., Kinuthia, J., Ishoso, D. K., Amoako, E., Agyare, E., … Adirieje, C. (2022). Assessment of Clinical Outcomes Among Children and Adolescents Hospitalized With COVID-19 in 6 Sub-Saharan African Countries. JAMA Pediatrics, 176(3), e216436. https://doi.org/10.1001/jamapediatrics.2021.6436

Negin, J., & Seeley, J. (2021). Incidence data do not count everyone. The Lancet HIV, 8(10), e603. https://doi.org/10.1016/S2352-3018(21)00243-5

Nkosi, B., Seeley, J., Chimbindi, N., Zuma, T., Kelley, M., & Shahmanesh, M. (2022). Putting research ethics in context: Rethinking vulnerability and agency within a research ethics case study on HIV prevention for young girls in South Africa. SSM - Qualitative Research in Health, 2, 100081. https://doi.org/10.1016/j.ssmqr.2022.100081

Nkosi, T., Chasara, C., Papadopoulos, A. O., Nguni, T. L., Karim, F., Moosa, M.-Y. S., Gazy, I., Jambo, K., COMMIT-KZN, Hanekom, W., Sigal, A., & Ndhlovu, Z. M. (2022). Unsuppressed HIV infection impairs T cell responses to SARS-CoV-2 infection and abrogates T cell cross-recognition. ELife, 11, e78374. https://doi.org/10.7554/eLife.78374

Nxumalo, V., Nxumalo, S., Smit, T., Khoza, T., Mdaba, F., Khumalo, T., Cislaghi, B., McGrath, N., Seeley, J., Shahmanesh, M., & Harling, G. (2022). Protocol: Mapping social networks, social influence and sexual health among youth in rural KwaZulu-Natal, the Sixhumene cohort study. Wellcome Open Research, 7, 164. https://doi.org/10.12688/wellcomeopenres.17896.1

O’Donnell, M. R., Padayatchi, N., Wolf, A., Zelnick, J., Daftary, A., Orrell, C., Nimmo, C., Baldwin, M., Boodhram, R., Maharaj, B., Amico, K. R., Naidoo, K., & Friedland, G. (2022). Bedaquiline adherence measured by electronic dose monitoring predicts clinical outcomes in the treatment of patients with multidrug-resistant tuberculosis and HIV/AIDS. JAIDS Journal of Acquired Immune Deficiency Syndromes. https://doi.org/10.1097/QAI.0000000000002940

Ogunshola, F. J., Smidt, W., Naidoo, A. F., Nkosi, T., Ngubane, T., Khaba, T., Baiyegunhi, O. O., Mahlobo, B., Rasehlo, S., Ngema, N., Jajbhay, I., Dong, K. L., Ramsuran, V., Pansegrouw, J., Ndung’u, T., Walker, B. D., Oliveria, T. de, & Ndhlovu, Z. M. (2022). Hypermethylation at the CXCR5 gene locus limits trafficking potential of CD8+ T cells into B-cell follicles during HIV-1 infection. Blood Advances, 6(6), 1904–1916. https://doi.org/10.1182/bloodadvances.2021006001

Orievulu, K. S., Ayeb-Karlsson, S., Ngema, S., Baisley, K., Tanser, F., Ngwenya, N., Seeley, J., Hanekom, W., Herbst, K., Kniveton, D., & Iwuji, C. C. (2022). Exploring linkages between drought and HIV treatment adherence in Africa: A systematic review. The Lancet Planetary Health, 6(4), e359–e370. https://doi.org/10.1016/S2542-5196(22)00016-X

Papadopoulos, A. O., & Ndhlovu, Z. M. (2022). Editing naive CD4+ T cells. Nature methods, 19(1), 36–37. https://doi.org/10.1038/s41592-021-01332-y

Phillips, A. N., Sibanda, E., Sikwese, K., Bansi-Matharu, L., Cambiano, V., Rodger, A., Lundgren, J., Shahmanesh, M., Gilks, C., Godfrey, C., Ehrenkranz, P., Hargreaves, J. R., Revill, P., & Cowan, F. (2022). Enabling timely HIV postexposure prophylaxis access in sub-Saharan Africa. AIDS, 36(10), 1473–1475. https://doi.org/10.1097/QAD.0000000000003258

Roberts, D. A., Cuadros, D., Vandormael, A., Gareta, D., Barnabas, R. V., Herbst, K., Tanser, F., & Akullian, A. (2022). Predicting the Risk of Human Immunodeficiency Virus Type 1 (HIV-1) Acquisition in Rural South Africa Using Geospatial Data. Clinical Infectious Diseases, 75(7), 1224–1231. https://doi.org/10.1093/cid/ciac069

Roberts, D. A., Cuadros, D., Vandormael, A., Gareta, D., Barnabas, R. V., Herbst, K., Tanser, F., & Akullian, A. (2022). Predicting the risk of HIV-1 acquisition in rural South Africa using geospatial data. Clinical Infectious Diseases, ciac069. https://doi.org/10.1093/cid/ciac069

Schaefer, R., Amparo da Costa Leite, P. H., Silva, R., Abdool Karim, Q., Akolo, C., Cáceres, C. F., Dourado, I., Green, K., Hettema, A., Hoornenborg, E., Jana, S., Kerschberger, B., Mahler, H., Matse, S., McManus, H., Molina, J.-M., Reza-Paul, S., Azwa, I., Shahmanesh, M., … Dalal, S. (2022). Kidney function in tenofovir disoproxil fumarate-based oral pre-exposure prophylaxis users: A systematic review and meta-analysis of published literature and a multi-country meta-analysis of individual participant data. The Lancet HIV, 9(4), e242–e253. https://doi.org/10.1016/S2352-3018(22)00004-2

Scheepers, C., Everatt, J., Amoako, D. G., Tegally, H., Wibmer, C. K., Mnguni, A., Ismail, A., Mahlangu, B., Lambson, B. E., Martin, D. P., Wilkinson, E., San, J. E., Giandhari, J., Manamela, N., Ntuli, N., Kgagudi, P., Cele, S., Richardson, S. I., Pillay, S., … Bhiman, J. N. (2022). Emergence and phenotypic characterization of the global SARS-CoV-2 C.1.2 lineage. Nature Communications, 13(1), 1976. https://doi.org/10.1038/s41467-022-29579-9

Seaman, M. S., Siedner, M. J., Boucau, J., Lavine, C. L., Ghantous, F., Liew, M. Y., Mathews, J., Singh, A., Marino, C., Regan, J., Uddin, R., Choudhary, M. C., Flynn, J. P., Chen, G., Stuckwisch, A. M., Lipiner, T., Kittilson, A., Melberg, M., Gilbert, R. F., … Lemieux, J. E. (2022). Vaccine Breakthrough Infection with the SARS-CoV-2 Delta or Omicron (BA.1) Variant Leads to Distinct Profiles of Neutralizing Antibody Responses [Preprint]. Infectious Diseases. https://doi.org/10.1101/2022.03.02.22271731

Sigal, A. (2022). Milder disease with Omicron: Is it the virus or the pre-existing immunity? Nature Reviews Immunology. https://doi.org/10.1038/s41577-022-00678-4

Sigal, A., Milo, R., & Jassat, W. (2022). Estimating disease severity of Omicron and Delta SARS-CoV-2 infections. Nature Reviews Immunology. https://doi.org/10.1038/s41577-022-00720-5

Sithole, N., Koole, O., Sausi, K., Krows, M., Schaafsma, T., Van Heerden, A., Shahmanesh, M., van Rooyen, H., Celum, C., Barnabas, R. V., & Shapiro, A. E. (2022). Secondary Distribution of HIV Self-Testing Kits to Social and Sexual Networks of PLWH in KwaZulu-Natal, South Africa. A Brief Report. Frontiers in Public Health, 10, 855625. https://doi.org/10.3389/fpubh.2022.855625

The CRyPTIC Consortium. (2022). Epidemiological cutoff values for a 96-well broth microdilution plate for high-throughput research antibiotic susceptibility testing of M. tuberculosis. European Respiratory Journal, 2200239. https://doi.org/10.1183/13993003.00239-2022

Turkova, A., Waalewijn, H., Chan, M. K., Bollen, P. D. J., Bwakura-Dangarembizi, M. F., Kekitiinwa, A. R., Cotton, M. F., Lugemwa, A., Variava, E., Ahimbisibwe, G. M., Srirompotong, U., Mumbiro, V., Amuge, P., Zuidewind, P., Ali, S., Kityo, C. M., Archary, M., Ferrand, R. A., Violari, A., … Zuidewind, P. (2022). Dolutegravir twice-daily dosing in children with HIV-associated tuberculosis: A pharmacokinetic and safety study within the open-label, multicentre, randomised, non-inferiority ODYSSEY trial. The Lancet HIV, 9(9), e627–e637. https://doi.org/10.1016/S2352-3018(22)00160-6

van Empel, E., De Vlieg, R. A., Harling, G., Marcus, M. E., Kahn, K., Bärnighausen, T. W., Montana, L., Choko, A. T., & Manne-Goehler, J. (2022). Reaching for the ‘first 95’: A cross-country analysis of HIV self-testing in nine countries in sub-Saharan Africa. AIDS, 36(2), 297–304. https://doi.org/10.1097/QAD.0000000000003106

Walker, N., Karim, F., Moosa, M., Moodley, S., Mazibuko, M., Khan, K., Sterling, T., van der Heijden, Y., Grant, A., Elkington, P., Pym, A., & Leslie, A. (2022). Elevated Plasma Matrix Metalloproteinase-8 associates with Sputum Culture Positivity in Pulmonary Tuberculosis. The Journal of Infectious Diseases, jiac160. https://doi.org/10.1093/infdis/jiac160

Walker, T. M., Miotto, P., Köser, C. U., Fowler, P. W., Knaggs, J., Iqbal, Z., Hunt, M., Chindelevitch, L., Farhat, M. R., Cirillo, D. M., Comas, I., Posey, J., Omar, S. V., Peto, T. E., Suresh, A., Uplekar, S., Laurent, S., Colman, R. E., Nathanson, C.-M., … Puyen, Z. M. (2022). The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: A genotypic analysis. The Lancet Microbe, 3(4), e265–e273. https://doi.org/10.1016/S2666-5247(21)00301-3

Zanoni, B., Archary, M., Sibaya, T., Ramos, T., Donenberg, G., Shahmanesh, M., Celum, C., Pettifor, A., Bekker, L. G., & Haberer, J. (2022). Interventions addressing the adolescent HIV continuum of care in South Africa: A systematic review and modified Delphi analysis. BMJ Open, 12(4), e057797. https://doi.org/10.1136/bmjopen-2021-057797

Zuma, T., Seeley, J., Hlongwane, S., Chimbindi, N., Sherr, L., Floyd, S., Birdthistle, I., & Shahmanesh, M. (2022). A socio-ecological approach to understanding experiences and perceptions of a multilevel HIV prevention intervention: The determined, resilient, empowered, AIDS-free, mentored, and safe (DREAMS) partnership in uMkhanyakude, KwaZulu-Natal, South Africa. SSM - Qualitative Research in Health, 2, 100138. https://doi.org/10.1016/j.ssmqr.2022.100138

2021 Publications

Adeagbo, O., & Naidoo, K. (2021). Engaging the ‘Missing Men’ in the HIV Treatment Cascade: Creating a Tailored Intervention to Improve Men’s Uptake of HIV Care Services in Rural South Africa: A Study Protocol. International Journal of Environmental Research and Public Health, 18(7), 3709. https://doi.org/10.3390/ijerph18073709

Adriano Vieira, V., Adland, E., Malone, D. F. G., Martin, M. P., Groll, A., Ansari, M. A., Garcia-Guerrero, M. C., Puertas, M. C., Muenchhoff, M., Guash, C. F., Brander, C., Martinez-Picado, J., Bamford, A., Tudor-Williams, G., Ndung’u, T., Walker, B. D., Ramsuran, V., Frater, J., Jooste, P., … Goulder, P. J. R. (2021). An HLA-I signature favouring KIR-educated Natural Killer cells mediates immune control of HIV in children and contrasts with the HLA-B-restricted CD8+ T-cell-mediated immune control in adults. PLOS Pathogens, 17(11), e1010090. https://doi.org/10.1371/journal.ppat.1010090

Akullian, A., Vandormael, A., Miller, J.C., Bershteyn, A., Wenger, E., Cuadros, D., Gareta, D., Bärnighausen, T., Herbst, K., Tanser, F., (2021). Large age shifts in HIV-1 incidence patterns in KwaZulu-Natal, South Africa. Proc Natl Acad Sci USA, 118, e2013164118. https://doi.org/10.1073/pnas.2013164118

Asowata, O. E., Singh, A., Ngoepe, A., Herbert, N., Fardoos, R., Reddy, K., Zungu, Y., Nene, F., Mthabela, N., Ramjit, D., Karim, F., Govender, K., Ndung’u, T., Porterfield, J. Z., Adamson, J. H., Madela, F. G., Manzini, V. T., Anderson, F., Leslie, A., & Kløverpris, H. N. (2021). Irreversible depletion of intestinal CD4+ T-cells is associated with T-cell activation during chronic HIV infection. JCI Insight. https://doi.org/10.1172/jci.insight.146162

Benson, P., Litovsky, S., Steyn, A. C., Margaroli, C., Iriabho, E., & Anderson, P. (2021). Use of telepathology to facilitate COVID-19 research and education through an online COVID-19 autopsy biorepository. Journal of Pathology Informatics, 12(1), 48. https://doi.org/10.4103/jpi.jpi_15_21

Bernays, S., Lanyon, C., Tumwesige, E., Aswiime, A., Ngwenya, N., Dlamini, V., Shahmanesh, M., Seeley, J., (2021). ‘This is what is going to help me’: Developing a co-designed and theoretically informed harm reduction intervention for mobile youth in South Africa and Uganda. Global Public Health, 1–14. https://doi.org/10.1080/17441692.2021.1953105

Birdthistle, I., Carter, D. J., Mthiyane, N. T., Orindi, B. O., Muuo, S., Chimbindi, N., Ziraba, A., Shahmanesh, M., Baisley, K., & Floyd, S. (2021). Early impact of the DREAMS partnership on young women’s knowledge of their HIV status: Causal analysis of population-based surveys in Kenya and South Africa. Journal of Epidemiology and Community Health, jech-2020-216042. https://doi.org/10.1136/jech-2020-216042

Bor, J., Fischer, C., Modi, M., Richman, B., Kinker, C., King, R., Calabrese, S. K., Mokhele, I., Sineke, T., Zuma, T., Rosen, S., Bärnighausen, T., Mayer, K. H., & Onoya, D. (2021). Changing Knowledge and Attitudes Towards HIV Treatment-as-Prevention and “Undetectable = Untransmittable”: A Systematic Review. AIDS and Behavior, 25(12), 4209–4224. https://doi.org/10.1007/s10461-021-03296-8

Bozzani, F. M., Diaconu, K., Gomez, G. B., Karat, A. S., Kielmann, K., Grant, A. D., & Vassall, A. (2021). Using System Dynamics Modelling to Estimate the Costs of Relaxing Health System Constraints: A Case Study of Tuberculosis Prevention and Control Interventions in South Africa. Health Policy and Planning, czab155. https://doi.org/10.1093/heapol/czab155

Brinkmann, B., Davies, J. I., Witham, M. D., Harling, G., Bärnighausen, T., Bountogo, M., Siedner, M. J., Ouermi, L., Junghanns, J., Boubacar, C., Sié, A., Payne, C. F., & Kohler, I. V. (2021). Impairment in Activities of Daily Living and unmet need for care among older adults: A population-based study from Burkina Faso. The Journals of Gerontology: Series B, gbab041. https://doi.org/10.1093/geronb/gbab041

Bulstra, C. A., Reddy, C. L., Atun, R., Bärnighausen, T., & Hontelez, J. A. C. (2021). Impact of the COVID-19-related global recession on the financing of the global HIV response. AIDS, Publish Ahead of Print. https://doi.org/10.1097/QAD.0000000000002872

Cai, Y., Jaecklein, E., Mackenzie, J. S., Papavinasasundaram, K., Olive, A. J., Chen, X., Steyn, A. J. C., & Sassetti, C. M. (2021). Host immunity increases Mycobacterium tuberculosis reliance on cytochrome bd oxidase. PLOS Pathogens, 17(7), e1008911. https://doi.org/10.1371/journal.ppat.1008911

Cai, Y., Jaecklein, E., Mackenzie, J. S., Papavinasasundaram, K., Olive, A. J., Chen, X., Steyn, A. J. C., & Sassetti, C. M. (2021). Host immunity increases Mycobacterium tuberculosis reliance on cytochrome bd oxidase. PLOS Pathogens, 17(7), e1008911. https://doi.org/10.1371/journal.ppat.1008911

Cele, S., Gazy, I., Jackson, L., Hwa, S.-H., Tegally, H., Lustig, G., Giandhari, J., Pillay, S., Wilkinson, E., Naidoo, Y., Karim, F., Ganga, Y., Khan, K., Balazs, A. B., Gosnell, B. I., Hanekom, W., Moosa, M.-Y. S., Lessells, R. J., de Oliveira, T., & Sigal, A. (2021). Escape of SARS-CoV-2 501Y.V2 variants from neutralization by convalescent plasma. MedRxiv, 2021.01.26.21250224. https://doi.org/10.1101/2021.01.26.21250224

Cele, S., Jackson, L., Khoury, D. S., Khan, K., Moyo-Gwete, T., Tegally, H., San, J. E., Cromer, D., Scheepers, C., Amoako, D. G., Karim, F., Bernstein, M., Lustig, G., Archary, D., Smith, M., Ganga, Y., Jule, Z., Reedoy, K., Hwa, S.-H., Giandhari, J., Blackburn … Sigal, A. (2021). Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization. Nature. https://doi.org/10.1038/s41586-021-04387-1

Chappell, E., Thorne, C., Collins, I. J., Baisley, K., Yapa, H. M., Gareta, D., Bärnighausen, T., Herbst, K., & Judd, A. (2021). It ain’t what you do, it’s the way that you do it: The pitfalls of using routine data to measure early infant HIV diagnosis in HIV-exposed infants. PLOS ONE, 16(9), e0257496. https://doi.org/10.1371/journal.pone.0257496

Chen, S., Prettner, K., Kuhn, M., Geldsetzer, P., Wang, C., Bärnighausen, T., & Bloom, D. E. (2021). Climate and the spread of COVID-19. Scientific reports, 11(1), 9042. https://doi.org/10.1038/s41598-021-87692-z

Chetty-Makkan, C. M., deSanto, D., Lessells, R., Charalambous, S., Velen, K., Makgopa, S., Gumede, D., Fielding, K., & Grant, A. D. (2021). Exploring the promise and reality of ward-based primary healthcare outreach teams conducting TB household contact tracing in three districts of South Africa. PLOS ONE, 16(8), e0256033. https://doi.org/10.1371/journal.pone.0256033

Chetty-Makkan, C. M., Hoffmann, C. J., Charalambous, S., Botha, C., Ntshuntshe, S., Nkosi, N., & Kim, H.-Y. (2021). Youth Preferences for HIV Testing in South Africa: Findings from the Youth Action for Health (YA4H) Study Using a Discrete Choice Experiment. AIDS and Behavior, 25(1), 182–190. https://doi.org/10.1007/s10461-020-02960-9

Chimbindi, N., Birdthistle, I., Floyd, S., Harling, G., Mthiyane, N., Zuma, T., Hargreaves, J. R., Seeley, J., & Shahmanesh, M. (2020). Directed and target focused multi‐sectoral adolescent HIV prevention: Insights from implementation of the ‘DREAMS Partnership’ in rural South Africa. Journal of the International AIDS Society, 23(S5). https://doi.org/10.1002/jia2.25575

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Millar, J.R., Fatti, I., Mchunu, N., Bengu, N., Grayson, N.E., Adland, E., Bonsall, D., Archary, M., Matthews, P.C., Ndung’u, T., Goulder, P., (2021). Second generation mother-to-child HIV transmission in South Africa is characterised by poor outcomes. AIDS, Publish Ahead of Print. https://doi.org/10.1097/QAD.0000000000002915

Mlcochova, P., Kemp, S., Dhar, M. S., Papa, G., Meng, B., Ferreira, I. A. T. M., Datir, R., Collier, D. A., Albecka, A., Singh, S., Pandey, R., Brown, J., Zhou, J., Goonawardane, N., Mishra, S., Whittaker, C., Mellan, T., Marwal, R., Datta, M., … Gupta, R. K. (2021). SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion. Nature. https://doi.org/10.1038/s41586-021-03944-y

Molatlhegi, R. P., Ngcobo, S., Liebenberg, L. J. P., Ngcapu, S., Mabhula, A., Leslie, A., Mchunu, N., Zondi, M. M., Adamson, J. H., Govender, K., Samsunder, N., Karim, S. S. A., Karim, Q. A., Passmore, J. S., Sivro, A., & McKinnon, L. R. (2021). Genital and systemic immune effects of the injectable, contraceptive norethisterone enanthate (NET‐EN), in South African women. American Journal of Reproductive Immunology. https://doi.org/10.1111/aji.13411

More, S., Marakalala, M. J., & Sathekge, M. (2021). Tuberculosis: Role of Nuclear Medicine and Molecular Imaging With Potential Impact of Neutrophil-Specific Tracers. Frontiers in Medicine, 8, 758636. https://doi.org/10.3389/fmed.2021.758636

Mthiyane, N., Harling, G., Chimbindi, N., Baisley, K., Seeley, J., Dreyer, J., Zuma, T., Birdthistle, I., Floyd, S., McGrath, N., Tanser, F., Shahmanesh, M., & Sherr, L. (2021). Common mental disorders and HIV status in the context of DREAMS among adolescent girls and young women in rural KwaZulu-Natal, South Africa. BMC Public Health, 21(1), 478. https://doi.org/10.1186/s12889-021-10527-z

Munoz, A., Hayward, M. R., Bloom, S. M., Rocafort, M., Ngcapu, S., Mafunda, N. A., Xu, J., Xulu, N., Dong, M., Dong, K. L., Ismail, N., Ndung’u, T., Ghebermichael, M. S., & Kwon, D. S. (2021). Modeling the temporal dynamics of cervicovaginal microbiota identifies targets that may promote reproductive health. Microbiome, 9(1), 163. https://doi.org/10.1186/s40168-021-01096-9

Naidoo, K. K., Ndumnego, O. C., Ismail, N., Dong, K. L., & Ndung’u, T. (2021). Antigen Presenting Cells Contribute to Persistent Immune Activation Despite Antiretroviral Therapy Initiation During Hyperacute HIV-1 Infection. Frontiers in Immunology, 12, 738743. https://doi.org/10.3389/fimmu.2021.738743

NCD Risk Factor Collaboration (NCD-RisC), Iurilli, M. L., Zhou, B., Bennett, J. E., Carrillo-Larco, R. M., Sophiea, M. K., Rodriguez-Martinez, A., Bixby, H., Solomon, B. D., Taddei, C., Danaei, G., Di Cesare, M., Stevens, G. A., Riley, L. M., Savin, S., Cowan, M. J., Bovet, P., Damasceno, A., Chirita-Emandi, A., … Filippi, S. (2021). Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight. ELife, 10, e60060. https://doi.org/10.7554/eLife.60060

Nduati, E. W., Gorman, M. J., Sein, Y., Hermanus, T., Oyaro, I., Muema, D. M., Ndung’u, T., Alter, G., & Moore, P. L. (2021). Coordinated Fc-effector and neutralization functions in HIV-infected children define a window of opportunity for HIV vaccination. AIDS, Publish Ahead of Print. https://bit.ly/2UHJ9If

Ndung’u, T. (2021). Will Long-Acting Antiretroviral Therapy be a Game Changer Globally? Med, 2(2), 115–117. https://doi.org/10.1016/j.medj.2021.01.004

Ngwenya, N., Crang, C., Farquhar, M., Rintoul, R. C., Mahadeva, R., Calvert, L. D., Murray, S. A., & Barclay, S. (2021). Communicating uncertainty: Contrasting the communication experiences of patients with advanced COPD and incurable lung cancer. Family Practice, cmab024. https://doi.org/10.1093/fampra/cmab024

Ngwenya, N., Iwuji, C., Petersen, N., Myeni, N., Nxumalo, S., Ngema, U., Seeley, J. (2021). Investigation of post-trial access views among study participants and stakeholders using photovoice and semistructured interviews. J Med Ethics, medethics-2020-107011. https://doi.org/10.1136/medethics-2020-107011

Nkosi, B., Zanoni, B., Seeley, J., & Strode, A. (2021). The ethical‐legal requirements for adolescent self‐consent to research in sub‐Saharan Africa: A scoping review. Bioethics, bioe.12988. https://doi.org/10.1111/bioe.12988

Ogongo, P., Tezera, L. B., Ardain, A., Nhamoyebonde, S., Ramsuran, D., Singh, A., Ngoepe, A., Karim, F., Naidoo, T., Khan, K., Dullabh, K. J., Fehlings, M., Lee, B. H., Nardin, A., Lindestam Arlehamn, C. S., Sette, A., Behar, S. M., Steyn, A. J. C., Madansein, R., … Leslie, A. (2021). Tissue resident-like CD4+ T cells secreting IL-17 control Mycobacteria tuberculosis in the human lung. Journal of Clinical Investigation. https://doi.org/10.1172/JCI142014

Ojwach, Doty B. A., Paradise Madlala, Michelle Gordon, Thumbi Ndung’u, and Jaclyn K. Mann. 2021. “Vulnerable Targets in HIV-1 Pol for Attenuation-Based Vaccine Design.” Virology 554:1–8. doi: 10.1016/j.virol.2020.12.003

Olivier, Stephen, et al. “Pitfalls of Single Measurement Screening for Diabetes and Hypertension in Community-Based Settings.” Global Heart, vol. 16, no. 1, Dec. 2021, p. 79. DOI.org (Crossref), https://doi.org/10.5334/gh.1083.

Oluwafemi, A., Xulu, S., Dlamini, N., Luthuli, M., Mhlongo, T., Herbst, C., Shahmanesh, M., & Seeley, J. (2021). Transcription as a Key Phase of Data Analysis in Qualitative Research: Experience from KwaZulu-Natal, South Africa. Field Methods, 1525822X2198948. https://doi.org/10.1177/1525822X21989482

Orievulu, K. S., & Iwuji, C. C. (2021). Institutional Responses to Drought in a High HIV Prevalence Setting in Rural South Africa. International Journal of Environmental Research and Public Health, 19(1), 434. https://doi.org/10.3390/ijerph19010434

Reddy, K. P., Fitzmaurice, K. P., Scott, J. A., Harling, G., Lessells, R. J., Panella, C., Shebl, F. M., Freedberg, K. A., & Siedner, M. J. (2021). Clinical outcomes and cost-effectiveness of COVID-19 vaccination in South Africa. Nature Communications, 12(1), 6238. https://doi.org/10.1038/s41467-021-26557-5

Reichmann, M. T., Tezera, L. B., Vallejo, A. F., Vukmirovic, M., Xiao, R., Reynolds, J., Jogai, S., Wilson, S., Marshall, B., Jones, M. G., Leslie, A., D'Armiento, J. M., Kaminski, N., Polak, M. E., & Elkington, P. (2021). Integrated transcriptomic analysis of human tuberculosis granulomas and a biomimetic model identifies therapeutic targets. The Journal of clinical investigation, 148136. Advance online publication. https://doi.org/10.1172/JCI148136

Renju, Jenny, Janet Seeley, Mosa Moshabela, and Alison Wringe. 2021. “Understanding the Health Systems Impacts of Universal Test and Treat in Sub-Saharan Africa: The Shape UTT Study.” Global Public Health 16(2):161–66. doi: 10.1080/17441692.2020.1861317

Risher, K.A., Cori, A., Reniers, G., Marston, M., Calvert, C., Crampin, A., Dadirai, T., Dube, A., Gregson, S., Herbst, K., Lutalo, T., Moorhouse, L., Mtenga, B., Nabukalu, D., Newton, R., Price, A.J., Tlhajoane, M., Todd, J., Tomlin, K., Urassa, M., Vandormael, A., Fraser, C., Slaymaker, E., Eaton, J.W., (2021). Age patterns of HIV incidence in eastern and southern Africa: a modelling analysis of observational population-based cohort studies. The Lancet HIV, 8, e429–e439. https://doi.org/10.1016/S2352-3018(21)00069-2

Rochat, Tamsen J., et al. “An Evaluation of a Combined Psychological and Parenting Intervention for HIV-Positive Women Depressed in the Perinatal Period, to Enhance Child Development and Reduce Maternal Depression: Study Protocol for the Insika Yomama Cluster Randomised Controlled Trial.” Trials, vol. 22, no. 1, Dec. 2021, p. 914. DOI.org (Crossref), https://doi.org/10.1186/s13063-021-05672-0.

Rodel, H. E., Ferreira, I. A. T. M., Ziegler, C. G. K., Ganga, Y., Bernstein, M., Hwa, S.-H., Nargan, K., Lustig, G., Kaplan, G., Noursadeghi, M., Shalek, A. K., Steyn, A. J. C., & Sigal, A. (2021). Aggregated Mycobacterium tuberculosis Enhances the Inflammatory Response. Frontiers in Microbiology, 12, 757134. https://doi.org/10.3389/fmicb.2021.757134

Sanders, E. J., Agutu, C., Elst, E., Hassan, A., Gichuru, E., Mugo, P., Farquhar, C., Babigumira, J. B., Goodreau, S. M., Hamilton, D. T., Ndung’u, T., Sirengo, M., Chege, W., & Graham, S. M. (2021). Effect of an opt‐out point‐of‐care HIV‐1 nucleic acid testing intervention to detect acute and prevalent HIV infection in symptomatic adult outpatients and reduce HIV transmission in Kenya: A randomized controlled trial. HIV Medicine, hiv.13157. https://doi.org/10.1111/hiv.13157

Shahmanesh, M., Mthiyane, T. N., Herbst, C., Neuman, M., Adeagbo, O., Mee, P., Chimbindi, N., Smit, T., Okesola, N., Harling, G., McGrath, N., Sherr, L., Seeley, J., Subedar, H., Johnson, C., Hatzold, K., Terris-Prestholt, F., Cowan, F. M., & Corbett, E. L. (2021). Effect of peer-distributed HIV self-test kits on demand for biomedical HIV prevention in rural KwaZulu-Natal, South Africa: a three-armed cluster-randomised trial comparing social networks versus direct delivery. BMJ Global Health, 6(Suppl 4), e004574. https://doi.org/10.1136/bmjgh-2020-004574

Shahmanesh, M., Okesola, N., Chimbindi, N., Zuma, T., Mdluli, S., Mthiyane, N., Adeagbo, O., Dreyer, J., Herbst, C., McGrath, N., Harling, G., Sherr, L., Seeley, J., (2021). Thetha Nami: participatory development of a peer-navigator intervention to deliver biosocial HIV prevention for adolescents and youth in rural South Africa. BMC Public Health, 21, 1393. https://doi.org/10.1186/s12889-021-11399-z

Siedner, M. J. (2021). Ivermectin for the treatment of COVID-19 disease: Too good to pass up or too good to be true? Open Forum Infectious Diseases, ofab318. https://doi.org/10.1093/ofid/ofab318

Singer, S. N., Ndumnego, O. C., Kim, R. S., Ndung’u, T., Anastos, K., French, A., Churchyard, G., Paramithiothis, E., Kasprowicz, V. O., & Achkar, J. M. (2022). Plasma host protein biomarkers correlating with increasing Mycobacterium tuberculosis infection activity prior to tuberculosis diagnosis in people living with HIV. EBioMedicine, 75, 103787. https://doi.org/10.1016/j.ebiom.2021.103787

Singh, R., Ramsuran, V., Naranbhai, V., Yende-Zuma, N., Garrett, N., Mlisana, K., Dong, K.L., Walker, B.D., Abdool Karim, S.S., Carrington, M., Ndung’u, T. (2021). Epigenetic Regulation of BST-2 Expression Levels and the Effect on HIV-1 Pathogenesis. Front. Immunol., 12, 669241. https://doi.org/10.3389/fimmu.2021.669241

Sithole, N., Gunda, R., Koole, O., Krows, M., Schaafsma, T., Moshabela, M., Siedner, M. J., Celum, C., & Barnabas, R. V. (2021). Undisclosed Antiretroviral Therapy Use at Primary Health Care Clinics in Rural KwaZulu Natal South Africa: A DO-ART Trial Sub-study. AIDS and Behavior, 25(11), 3695–3703. https://doi.org/10.1007/s10461-021-03319-4

Sithole, N., Gunda, R., Koole, O., Krows, M., Schaafsma, T., Moshabela, M., Siedner, M.J., Celum, C., Barnabas, R.V. (2021). Undisclosed Antiretroviral Therapy Use at Primary Health Care Clinics in Rural KwaZulu Natal South Africa: A DO-ART Trial Sub-study. AIDS Behav., https://doi.org/10.1007/s10461-021-03319-4

Sithole, N., Shahmanesh, M., Koole, O., Krows, M., Schaafsma, T., Siedner, M. J., Celum, C., Barnabas, R. V., & Shapiro, A. E. (2021). Implementation of HIV Self-Testing to Reach Men in Rural uMkhanyakude, KwaZulu-Natal, South Africa. A DO-ART Trial Sub Study. Frontiers in Public Health, 9, 652887. https://doi.org/10.3389/fpubh.2021.652887

Skelly, D. T., Harding, A. C., Gilbert-Jaramillo, J., Knight, M. L., Longet, S., Brown, A., Adele, S., Adland, E., Brown, H., Medawar Laboratory Team, Chinnakannan, S., Donnison, T., Ali, M., Rongkard, P., Pace, M., Zacharopoulou, P., Robinson, N., Csala, A., De Lara, C., … James, W. S. (2021). Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern. Nature Communications, 12(1), 5061. https://doi.org/10.1038/s41467-021-25167-5

Snyman, J., Hwa, S.-H., Krause, R., Muema, D., Reddy, T., Ganga, Y., Karim, F., Leslie, A., Sigal, A., Ndung’u, T., & the COMMIT-KZN Team. (2021). Similar antibody responses against SARS-CoV-2 in HIV uninfected and infected individuals on antiretroviral therapy during the first South African infection wave. Clinical Infectious Diseases, ciab758. https://doi.org/10.1093/cid/ciab758

Snyman, J., Sanders, E. J., & Ndung’u, T. (2021). COVID-19 in Africa: Preexisting immunity and HIV. AIDS, 35(14), 2391–2393. https://doi.org/10.1097/QAD.0000000000003079

Tanser, F. C., Kim, H., Mathenjwa, T., Shahmanesh, M., Seeley, J., Matthews, P., Wyke, S., McGrath, N., Adeagbo, O., Sartorius, B., Yapa, H. M., Zuma, T., Zeitlin, A., Blandford, A., Dobra, A., & Bärnighausen, T. (2021). Home‐Based Intervention to Test and Start (HITS): A community‐randomized controlled trial to increase HIV testing uptake among men in rural South Africa. Journal of the International AIDS Society, 24(2). https://doi.org/10.1002/jia2.25665

Tegally, H., Wilkinson, E., Giovanetti, M., Iranzadeh, A., Fonseca, V., Giandhari, J., Doolabh, D., Pillay, S., San, E. J., Msomi, N., Mlisana, K., von Gottberg, A., Walaza, S., Allam, M., Ismail, A., Mohale, T., Glass, A. J., Engelbrecht, S., Van Zyl, G., l, Preiser, W., Petruccione, F., Sigal, A., Hardie, D., Marais, G., Hsiao, M., Korsman, S., Davies, M., Tyers, L., Mudau, I., York, D., Maslo, C., Goedhals, D., Abrahams, S., Laguda-Akingba, O., Alisoltani-Dehkordi, A., Godzik, A., Wibmer, C.K., Sewell, B.T., Lourenço, J., Alcantara, L.C.Jr., Pond, S.L.K., Weaver, S., Martin, D., Lessells, R.J., Bhiman, J.N., Williamson, C., … de Oliveira, T. (2021). Emergence of a SARS-CoV-2 variant of concern with mutations in spike glycoprotein. Nature. https://doi.org/10.1038/s41586-021-03402-9

Tegally, H., Wilkinson, E., Lessells, R. J., Giandhari, J., Pillay, S., Msomi, N., Mlisana, K., Bhiman, J. N., von Gottberg, A., Walaza, S., Fonseca, V., Allam, M., Ismail, A., Glass, A. J., Engelbrecht, S., Van Zyl, G., Preiser, W., Williamson, C., Petruccione, F., … de Oliveira, T. (2021). Sixteen novel lineages of SARS-CoV-2 in South Africa. Nature Medicine. https://doi.org/10.1038/s41591-021-01255-3

The CITIID-NIHR BioResource COVID-19 Collaboration, The COVID-19 Genomics UK (COG-UK) consortium, Collier, D. A., De Marco, A., Ferreira, I. A. T. M., Meng, B., Datir, R., Walls, A. C., Kemp S, S. A., Bassi, J., Pinto, D., Fregni, C. S., Bianchi, S., Tortorici, M. A., Bowen, J., Culap, K., Jaconi, S., Cameroni, E., Snell, G., … Gupta, R. K. (2021). Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies. Nature. https://doi.org/10.1038/s41586-021-03412-7

The CITIID-NIHR BioResource COVID-19 Collaboration, The COVID-19 Genomics UK (COG-UK) Consortium, Kemp, S. A., Collier, D. A., Datir, R. P., Ferreira, I. A. T. M., Gayed, S., Jahun, A., Hosmillo, M., Rees-Spear, C., Mlcochova, P., Lumb, I. U., Roberts, D. J., Chandra, A., Temperton, N., Sharrocks, K., Blane, E., Modis, Y., Leigh, K., … Gupta, R. K. (2021). SARS-CoV-2 evolution during treatment of chronic infection. Nature. https://doi.org/10.1038/s41586-021-03291-y

The NHLBI LungMap Consortium, The Human Cell Atlas Lung Biological Network, Muus, C., Luecken, M. D., Eraslan, G., Sikkema, L., Waghray, A., Heimberg, G., Kobayashi, Y., Vaishnav, E. D., Subramanian, A., Smillie, C., Jagadeesh, K. A., Duong, E. T., Fiskin, E., Triglia, E. T., Ansari, M., Cai, P., Lin, B., … Ziegler, C. G. K. (2021). Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics. Nature Medicine, 27(3), 546–559. https://doi.org/10.1038/s41591-020-01227-z

Tomita, A., Leyna, G. H., Kim, H.-Y., Moodley, Y., Mpolya, E., Mogeni, P., Cuadros, D. F., Dzomba, A., Vandormael, A., Bärnighausen, T., & Tanser, F. (2021). Patterns of multimorbidity and their association with hospitalisation: A population-based study of older adults in urban Tanzania. Age and Ageing, afab046. https://doi.org/10.1093/ageing/afab046

Tsai, A. C., Harling, G., Reynolds, Z., Gilbert, R. F., & Siedner, M. J. (2021). Coronavirus Disease 2019 (COVID-19) Transmission in the United States Before Versus After Relaxation of Statewide Social Distancing Measures. Clinical Infectious Diseases, 73(Supplement_2), S120–S126. https://doi.org/10.1093/cid/ciaa1502

Turbé, V., Herbst, C., Mngomezulu, T., Meshkinfamfard, S., Dlamini, N., Mhlongo, T., Smit, T., Cherepanova, V., Shimada, K., Budd, J., Arsenov, N., Gray, S., Pillay, D., Herbst, K., Shahmanesh, M., & McKendry, R. A. (2021). Deep learning of HIV field-based rapid tests. Nature Medicine, 10.1038/s41591-021-01384-9. Advance online publication. https://doi.org/10.1038/s41591-021-01384-9

Turkova A, White E, Mujuru HA, Kekitiinwa AR, Kityo CM, Violari A, Lugemwa A, Cressey TR, Musoke P, Variava E, Cotton MF, Archary M, Puthanakit T, Behuhuma O, Kobbe R, Welch SB, Bwakura-Dangarembizi M, Amuge P, Kaudha E, Barlow-Mosha L, Makumbi S, Ramsagar N, Ngampiyaskul C, Musoro G, Atwine L, Liberty A, Musiime V, Bbuye D, Ahimbisibwe GM, Chalermpantmetagul S, Ali S, Sarfati T, Wynne B, Shakeshaft C, Colbers A, Klein N, Bernays S, Saïdi Y, Coelho A, Grossele T, Compagnucci A, Giaquinto C, Rojo P, Ford D, Gibb DM; ODYSSEY Trial Team. (2021). Dolutegravir as First- or Second-Line Treatment for HIV-1 Infection in Children. New England Journal of Medicine, 385(27), 2531–2543. https://doi.org/10.1056/NEJMoa2108793

van Empel, E., de Vlieg, R. A., Montana, L., Gómez-Olivé, F. X., Kahn, K., Tollman, S., Berkman, L., Bärnighausen, T. W., & Manne-Goehler, J. (2021). Older Adults Vastly Overestimate Both HIV Acquisition Risk and HIV Prevalence in Rural South Africa. Archives of Sexual Behavior. https://doi.org/10.1007/s10508-021-01982-1

Wenlock, R. D., Brown, C. S., Iwuji, C., & Vera, J. H. (2021). Can I go back to work? A case of persistent SARS-CoV-2 with advanced untreated HIV infection. International Journal of STD & AIDS, 095646242110516. https://doi.org/10.1177/09564624211051631

Williams, Shannon M., Jenny Renju, Mosa Moshabela, and Alison Wringe. 2021. “Understanding the Influence of Health Systems on Women’s Experiences of Option B+: A Meta-Ethnography of Qualitative Research from Sub-Saharan Africa.” Global Public Health 16(2):167–85. doi: 10.1080/17441692.2020.1851385

Wong, E. B., Olivier, S., Gunda, R., Koole, O., Surujdeen, A., Gareta, D., Munatsi, D., Modise, T. H., Dreyer, J., Nxumalo, S., Smit, T. K., Ording-Jespersen, G., Mpofana, I. B., Khan, K., Sikhosana, Z., Moodley, S., Shen, Y. J., Khoza, T., Mhlongo, N., Bucibo, S., Nyamande K, Baisley K. J, Cuadros D, Tanser F, Grant A. D, Herbst K, Seeley J, Hanekom W.A, Ndung'u T, Siedner M. J, Pillay D; Vukuzazi Team. (2021). Convergence of infectious and non-communicable disease epidemics in rural South Africa: a cross-sectional, population-based multimorbidity study. The Lancet Global health, 9(7), e967–e976. https://doi.org/10.1016/S2214-109X(21)00176-5

Yapa, H. M., Kim, H.-Y., Petoumenos, K., Post, F. A., Jiamsakul, A., De Neve, J.-W., Tanser, F., Iwuji, C., Baisley, K., Shahmanesh, M., Pillay, D., Siedner, M. J., Bärnighausen, T., & Bor, J. (2021). CD4+ T-cell count at antiretroviral therapy initiation in the “treat all” era in rural South Africa: An interrupted time series analysis. Clinical Infectious Diseases, ciab650. https://doi.org/10.1093/cid/ciab650

Zuma, T., King, R., Ngwenya, N., Kasujja, F. X., Chimbindi, N., Kawuma, R., Shahmanesh, M., Bernays, S., & Seeley, J. (2021). Lives Interrupted: Navigating Hardship During COVID-19 Provides Lessons in Solidarity and Visibility for Mobile Young People in South Africa and Uganda. Progress in Development Studies, 21(4), 419–434. https://doi.org/10.1177/1464993421998209

2020 Publications

Adeagbo, O., Kim, H.-Y., Tanser, F., Xulu, S., Dlamini, N., Gumede, V., Mathenjwa, T., Bärnighausen, T., McGrath, N., Blandford, A., Seeley, J., & Shahmanesh, M. (2020). Acceptability of a tablet-based application to support early HIV testing among men in rural KwaZulu-Natal, South Africa: A mixed method study. AIDS Care, 1–8. https://doi.org/10.1080/09540121.2020.1742867

Adland, E., Millar, J., Bengu, N., Muenchhoff, M., Fillis, R., Sprenger, K., Ntlantsana, V., Roider, J., Vieira, V., Govender, K., Adamson, J., Nxele, N., Ochsenbauer, C., Kappes, J., Mori, L., van Lobenstein, J., Graza, Y., Chinniah, K., Kapongo, C., … Goulder, P. (2020). Sex-specific innate immune selection of HIV-1 in utero is associated with increased female susceptibility to infection. Nature Communications, 11(1), 1767. https://doi.org/10.1038/s41467-020-15632-y

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Nakasone, S. E., Chimbindi, N., Mthiyane, N., Nkosi, B., Zuma, T., Baisley, K., Dreyer, J., Pillay, D., Floyd, S., Birdthistle, I., Seeley, J., & Shahmanesh, M. (2020). “They have this not care – don’t care attitude:” A Mixed Methods Study Evaluating Community Readiness for Oral PrEP in Adolescent Girls and Young Women in a Rural Area of South Africa. AIDS Research and Therapy, 17(1), 55. https://doi.org/10.1186/s12981-020-00310-2

Narayanan, G. A., McLaren, J. E., Meermeier, E. W., Ladell, K., Swarbrick, G. M., Price, D. A., Tran, J. G., Worley, A. H., Vogt, T., Wong, E. B., & Lewinsohn, D. M. (2020). The MAIT TCRβ chain contributes to discrimination of microbial ligand. Immunology & Cell Biology, imcb.12370. https://doi.org/10.1111/imcb.12370

Ndlovu, B., Gounder, K., Muema, D., Raju, N., Hermanus, T., Mthethwa, Q., Robertson, K., Walker, B. D., Georgiev, I. S., Morris, L., Moore, P. L., & Ndung’u, T. (2020a). Envelope characteristics in individuals who developed neutralizing antibodies targeting different epitopes in HIV-1 subtype C infection. Virology, 546, 1–12. https://doi.org/10.1016/j.virol.2020.03.003

Ndlovu, L. N., Peetluk, L., Moodley, S., Nhamoyebonde, S., Ngoepe, A. T., Mazibuko, M., Khan, K., Karim, F., Pym, A. S., Maruri, F., Moosa, M.-Y. S., van der Heijden, Y. F., Sterling, T. R., & Leslie, A. (2020). Increased Neutrophil Count and Decreased Neutrophil CD15 Expression Correlate With TB Disease Severity and Treatment Response Irrespective of HIV Co-infection. Frontiers in Immunology, 11, 1872. https://doi.org/10.3389/fimmu.2020.01872

Ngwenya, N., Nkosi, B., Mchunu, L. S., Ferguson, J., Seeley, J., & Doyle, A. M. (2020). Behavioural and socio-ecological factors that influence access and utilisation of health services by young people living in rural KwaZulu-Natal, South Africa: Implications for intervention. PLOS ONE, 15(4), e0231080. https://doi.org/10.1371/journal.pone.0231080

Nimmo, C., Brien, K., Millard, J., Grant, A. D., Padayatchi, N., Pym, A. S., O’Donnell, M., Goldstein, R., Breuer, J., & Balloux, F. (2020). Dynamics of within-host Mycobacterium tuberculosis diversity and heteroresistance during treatment. EBioMedicine, 55, 102747. https://doi.org/10.1016/j.ebiom.2020.102747

Nimmo, C., Millard, J., Brien, K., Moodley, S., van Dorp, L., Lutchminarain, K., Wolf, A., Grant, A. D., Balloux, F., Pym, A. S., Padayatchi, N., & O’Donnell, M. (2020). Bedaquiline resistance in drug-resistant tuberculosis HIV co-infected patients. European Respiratory Journal, 1902383. https://doi.org/10.1183/13993003.02383-2019

Nimmo, C., Millard, J., van Dorp, L., Brien, K., Moodley, S., Wolf, A., Grant, A. D., Padayatchi, N., Pym, A. S., Balloux, F., & O’Donnell, M. (2020). Population-level emergence of bedaquiline and clofazimine resistance-associated variants among patients with drug-resistant tuberculosis in southern Africa: A phenotypic and phylogenetic analysis. The Lancet Microbe, 1(4), e165–e174. https://doi.org/10.1016/S2666-5247(20)30031-8

Nyakato, P., Davies, M.-A., Technau, K.-G., Fatti, G., Rabie, H., Tanser, F., Boulle, A., Wood, R., Eley, B., Sawry, S., Giddy, J., Sipambo, N., Kuhn, L., Fairlie, L., & for the International epidemiology Database to Evaluate AIDS-Southern Africa (IeDEA-SA) Collaboration. (2020). Virologic response to efavirenz-based first-line antiretroviral therapy in children with previous exposure to antiretrovirals to prevent mother-to-child transmission. PLOS ONE, 15(5), e0233693. https://doi.org/10.1371/journal.pone.0233693

Ogongo, P., Steyn, A. J. C., Karim, F., Dullabh, K. J., Awala, I., Madansein, R., Leslie, A., & Behar, S. M. (2019). Differential skewing of donor-unrestricted and γδ T cell repertoires in tuberculosis-infected human lungs. Journal of Clinical Investigation, 130(1), 214–230. https://doi.org/10.1172/JCI130711

Phillips, A. N., Bansi-Matharu, L., Venter, F., Havlir, D., Pozniak, A., Kuritzkes, D. R., Wensing, A., Lundgren, J. D., Pillay, D., Mellors, J., Cambiano, V., Jahn, A., Apollo, T., Mugurungi, O., Ripin, D., Da Silva, J., Raizes, E., Ford, N., Siberry, G. K., … Bertagnolio, S. (2020). Updated assessment of risks and benefits of dolutegravir versus efavirenz in new antiretroviral treatment initiators in sub-Saharan Africa: Modelling to inform treatment guidelines. The Lancet HIV, S235230181930400X. https://doi.org/10.1016/S2352-3018(19)30400-X

Pillay, T., Cornell, M., Fox, M. P., Euvrard, J., Fatti, G., Technau, K.-G., Sipambo, N., Prozesky, H., Eley, B., Tanser, F., & Johnson, L. F. (2020). Recording of HIV viral loads and viral suppression in South African patients receiving antiretroviral treatment: A multicentre cohort study. Antiviral Therapy. https://doi.org/10.3851/IMP3371

Pillaye, J. N., Marakalala, M. J., Khumalo, N., Spearman, W., & Ndlovu, H. (2020). Mechanistic insights into antiretroviral drug‐induced liver injury. Pharmacology Research & Perspectives, 8(4). https://doi.org/10.1002/prp2.598

Rahman, Md. A., Cumming, B. M., Addicott, K. W., Pacl, H. T., Russell, S. L., Nargan, K., Naidoo, T., Ramdial, P. K., Adamson, J. H., Wang, R., & Steyn, A. J. C. (2020). Hydrogen sulfide dysregulates the immune response by suppressing central carbon metabolism to promote tuberculosis. Proceedings of the National Academy of Sciences, 117(12), 6663–6674. https://doi.org/10.1073/pnas.1919211117

Reddy, K. P., Shebl, F. M., Foote, J. H. A., Harling, G., Scott, J. A., Panella, C., Flanagan, C., Hyle, E. P., Neilan, A. M., Mohareb, A. M., Bekker, L.-G., Lessells, R. J., Ciaranello, A. L., Wood, R., Losina, E., Freedberg, K. A., Kazemian, P., & Siedner, M. J. (2020). Cost-effectiveness of public health strategies for COVID-19 epidemic control in South Africa [Preprint]. Public and Global Health. https://doi.org/10.1101/2020.06.29.20140111

Renju, J., Rice, B., Songo, J., Hassan, F., Chimukuche, R. S., McLean, E., Kalua, T., Kajoka, D., Geubbels, E., Moshabela, M., Seeley, J., & Wringe, A. (2020). Influence of evolving HIV treatment guidance on CD4 counts and viral load monitoring: A mixed-methods study in three African countries. Global Public Health, 1–17. https://doi.org/10.1080/17441692.2020.1805785

Rosenberg, M., Gómez‐Olivé, F. X., Wagner, R. G., Rohr, J., Payne, C. F., Berkman, L., Kahn, K., Tollman, S., Bärnighausen, T., & Kobayashi, L. C. (2020). The relationships between cognitive function, literacy and HIV status knowledge among older adults in rural South Africa. Journal of the International AIDS Society, 23(3). https://doi.org/10.1002/jia2.25457

Saini, V., Chinta, K. C., Reddy, V. P., Glasgow, J. N., Stein, A., Lamprecht, D. A., Rahman, Md. A., Mackenzie, J. S., Truebody, B. E., Adamson, J. H., Kunota, T. T. R., Bailey, S. M., Moellering, D. R., Lancaster, J. R., & Steyn, A. J. C. (2020). Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis. Nature Communications, 11(1), 557. https://doi.org/10.1038/s41467-019-14132-y

Shapiro, A. E., Heerden, A., Krows, M., Sausi, K., Sithole, N., Schaafsma, T. T., Koole, O., Rooyen, H., Celum, C. L., & Barnabas, R. V. (2020). An implementation study of oral and blood‐based HIV self‐testing and linkage to care among men in rural and peri‐urban KwaZulu‐Natal, South Africa. Journal of the International AIDS Society, 23(S2). https://doi.org/10.1002/jia2.25514

Siedner, M. J., Baisley, K., Koole, O., Mpofana, I., Ording-Jespersen, G., Matthews, P., Herbst, K., Smit, T., & Pillay, D. (2020). Does antiretroviral therapy use affect the accuracy of HIV rapid diagnostic assays? Experience from a demographic health and surveillance site in rural South Africa. Diagnostic Microbiology and Infectious Disease, 115031. https://doi.org/10.1016/j.diagmicrobio.2020.115031

Siedner, M. J., Harling, G., Derache, A., Smit, T., Khoza, T., Gunda, R., Mngomezulu, T., Gareta, D., Majozi, N., Ehlers, E., Dreyer, J., Nxumalo, S., Dayi, N., Ording-Jesperson, G., Ngwenya, N., Wong, E., Iwuji, C., Shahmanesh, M., Seeley, J., … Herbst, K. (2020). Protocol: Leveraging a demographic and health surveillance system for Covid-19 Surveillance in rural KwaZulu-Natal. Wellcome Open Research, 5, 109. https://doi.org/10.12688/wellcomeopenres.15949.1

Siedner, M. J., Kraemer, J. D., Meyer, M. J., Harling, G., Mngomezulu, T., Gabela, P., Dlamini, S., Gareta, D., Majozi, N., Ngwenya, N., Reynolds, Z., Seeley, J., Wong, E., Iwuji, C., Shahmanesh, M., Hanekom, W., & Herbst, K. (2020). Access to primary healthcare during lockdown measures for COVID-19 in rural South Africa: A longitudinal cohort study [Preprint]. Health Systems and Quality Improvement. https://doi.org/10.1101/2020.05.15.20103226

Singh, A., Kazer, S. W., Roider, J., Krista, K. C., Millar, J., Asowata, O. E., Ngoepe, A., Ramsuran, D., Fardoos, R., Ardain, A., Muenchhoff, M., Kuhn, W., Karim, F., Ndung’u, T., Shalek, A. K., Goulder, P., Leslie, A., & Kløverpris, H. N. (2020). Innate Lymphoid Cell Activation and Sustained Depletion in Blood and Tissue of Children Infected with HIV from Birth Despite Antiretroviral Therapy. Cell Reports, 32(11), 108153. https://doi.org/10.1016/j.celrep.2020.108153

Suchard, M. S., Adu-Gyamfi, C. G., Cumming, B. M., & Savulescu, D. M. (2020). Evolutionary Views of Tuberculosis: Indoleamine 2,3-Dioxygenase Catalyzed Nicotinamide Synthesis Reflects Shifts in Macrophage Metabolism: Indoleamine 2,3-Dioxygenase Reflects Altered Macrophage Metabolism During Tuberculosis Pathogenesis. BioEssays: News and Reviews in Molecular, Cellular and Developmental Biology, 42(5), e1900220. https://doi.org/10.1002/bies.201900220

Sweeney, S., Vassall, A., Guinness, L., Siapka, M., Chimbindi, N., Mudzengi, D., & Gomez, G. B. (2020). Examining Approaches to Estimate the Prevalence of Catastrophic Costs Due to Tuberculosis from Small-Scale Studies in South Africa. PharmacoEconomics. https://doi.org/10.1007/s40273-020-00898-3

Tanser, F., Kim, H.-Y., Vandormael, A., Iwuji, C., & Bärnighausen, T. (2020). Opportunities and Challenges in HIV Treatment as Prevention Research: Results from the ANRS 12249 Cluster-Randomized Trial and Associated Population Cohort. Current HIV/AIDS Reports. https://doi.org/10.1007/s11904-020-00487-1

Tezera, L. B., Bielecka, M. K., Ogongo, P., Walker, N. F., Ellis, M., Garay-Baquero, D. J., Thomas, K., Reichmann, M. T., Johnston, D. A., Wilkinson, K. A., Ahmed, M., Jogai, S., Jayasinghe, S. N., Wilkinson, R. J., Mansour, S., Thomas, G. J., Ottensmeier, C. H., Leslie, A., & Elkington, P. T. (2020). Anti-PD-1 immunotherapy leads to tuberculosis reactivation via dysregulation of TNF-α. ELife, 9, e52668. https://doi.org/10.7554/eLife.52668

Tlali, M., Fielding, K. L., Karat, A. S., Hoffmann, C. J., Muravha, T., Grant, A. D., & Charalambous, S. (2020). Sensitivity of the lateral flow urine lipoarabinomannan assay in ambulant adults with advanced HIV disease: Data from the TB Fast Track study. Transactions of The Royal Society of Tropical Medicine and Hygiene, 114(8), 556–560. https://doi.org/10.1093/trstmh/traa018

Tomita, A., Cuadros, D. F., Mabhaudhi, T., Sartorius, B., Ncama, B. P., Dangour, A. D., Tanser, F., Modi, A. T., Slotow, R., & Burns, J. K. (2020). Spatial clustering of food insecurity and its association with depression: A geospatial analysis of nationally representative South African data, 2008–2015. Scientific Reports, 10(1), 13771. https://doi.org/10.1038/s41598-020-70647-1

Umviligihozo, G., Cobarrubias, K. D., Chandrarathna, S., Jin, S. W., Reddy, N., Byakwaga, H., Muzoora, C., Bwana, M. B., Lee, G. Q., Hunt, P. W., Martin, J. N., Brumme, C. J., Bangsberg, D. R., Karita, E., Allen, S., Hunter, E., Ndung’u, T., Brumme, Z. L., & Brockman, M. A. (2020). Differential Vpu-Mediated CD4 and Tetherin Downregulation Functions among Major HIV-1 Group M Subtypes. Journal of Virology, 94(14), e00293-20, /jvi/94/14/JVI.00293-20.atom. https://doi.org/10.1128/JVI.00293-20

Vandormael, A., Cuadros, D., Dobra, A., Bärnighausen, T., & Tanser, F. (2020). HIV incidence declines in a rural South African population: A G-imputation approach for inference. BMC Public Health, 20(1), 1205. https://doi.org/10.1186/s12889-020-09193-4

Vandormael, A., Cuadros, D., Kim, H.-Y., Bärnighausen, T., & Tanser, F. (2020). The state of the HIV epidemic in rural KwaZulu-Natal, South Africa: A novel application of disease metrics to assess trajectories and highlight areas for intervention. International Journal of Epidemiology, dyz269. https://doi.org/10.1093/ije/dyz269

Vandormael, Alain, Maya Adam, Merlin Greuel, and Till Bärnighausen. 2020. “An Entertainment-Education Approach to Prevent COVID-19 Spread: Study Protocol for a Multi-Site Randomized Controlled Trial.” Trials 21(1):1025. doi: 10.1186/s13063-020-04942-7.

Yapa, H. M., Drayne, R., Klein, N., De Neve, J.-W., Petoumenos, K., Jiamsakul, A., Herbst, C., Pillay, D., Post, F. A., & Bärnighausen, T. (2020). Infant feeding knowledge and practice vary by maternal HIV status: A nested cohort study in rural South Africa. International Breastfeeding Journal, 15(1), 77. https://doi.org/10.1186/s13006-020-00317-5

Zaniewski, E., Dao Ostinelli, C. H., Chammartin, F., Maxwell, N., Davies, M., Euvrard, J., Dijk, J., Bosomprah, S., Phiri, S., Tanser, F., Sipambo, N., Muhairwe, J., Fatti, G., Prozesky, H., Wood, R., Ford, N., Fox, M. P., & Egger, M. (2020). Trends in CD4 and viral load testing 2005 to 2018: Multi‐cohort study of people living with HIV in Southern Africa. Journal of the International AIDS Society, 23(7). https://doi.org/10.1002/jia2.25546

Ziegler, C. G. K., Allon, S. J., Nyquist, S. K., Mbano, I. M., Miao, V. N., Tzouanas, C. N., Cao, Y., Yousif, A. S., Bals, J., Hauser, B. M., Feldman, J., Muus, C., Wadsworth, M. H., Kazer, S. W., Hughes, T. K., Doran, B., Gatter, G. J., Vukovic, M., Taliaferro, F., … Zhang, K. (2020). SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues. Cell, 181(5), 1016-1035.e19. https://doi.org/10.1016/j.cell.2020.04.035

2019 Publications

Abeler-Dörner, L., Grabowski, M. K., Rambaut, A., Pillay, D., & Fraser, C. (2019). PANGEA-HIV 2: Phylogenetics And Networks for Generalised Epidemics in Africa. Current Opinion in HIV and AIDS, 14(3), 173–180. https://doi.org/10.1097/COH.0000000000000542

Adam, M., McMahon, S. A., Prober, C., & Bärnighausen, T. (2019). Human-Centered Design of Video-Based Health Education: An Iterative, Collaborative, Community-Based Approach. Journal of Medical Internet Research, 21(1), e12128. https://doi.org/10.2196/12128

Adam, M., Tomlinson, M., Le Roux, I., LeFevre, A. E., McMahon, S. A., Johnston, J., … Bärnighausen, T. (2019). The Philani MOVIE study: a cluster-randomized controlled trial of a mobile video entertainment-education intervention to promote exclusive breastfeeding in South Africa. BMC Health Services Research, 19(1), 211. https://doi.org/10.1186/s12913-019-4000-x

Adeagbo, O. A., Mthiyane, N., Herbst, C., Mee, P., Neuman, M., Dreyer, J., Chimbindi, N., Smit, T., Okesola, N., Johnson, C., Hatzold, K., Seeley, J., Cowan, F., Corbett, L., & Shahmanesh, M. (2019). Cluster randomised controlled trial to determine the effect of peer delivery HIV self-testing to support linkage to HIV prevention among young women in rural KwaZulu-Natal, South Africa: A study protocol. BMJ Open, 9(12), e033435. https://doi.org/10.1136/bmjopen-2019-033435

Adeagbo, O., Herbst, C., Blandford, A., McKendry, R., Estcourt, C., Seeley, J., Shahmanesh, M., 2019. Exploring People’s Candidacy for Mobile Health–Supported HIV Testing and Care Services in Rural KwaZulu-Natal, South Africa: Qualitative Study. J Med Internet Res 21, e15681. https://doi.org/10.2196/15681

Akilimali, N. A., Muema, D. M., Specht, C., Chang, C. C., Moosa, M.-Y. S., Levitz, S. M., … Ndung’u, T. (2019). Cryptococcosis-associated Immune Reconstitution Inflammatory Syndrome is associated with Dysregulation of IL-7/IL-7 Receptor Signaling Pathway in T-cells and Monocyte Activation: JAIDS Journal of Acquired Immune Deficiency Syndromes, 1. https://doi.org/10.1097/QAI.0000000000001946

Ardain, A., Domingo-Gonzalez, R., Das, S., Kazer, S. W., Howard, N. C., Singh, A., … Khader, S. A. (2019). Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis. Nature, 570(7762), 528–532. https://doi.org/10.1038/s41586-019-1276-2

Ardain, A., Marakalala, M.J., Leslie, A., 2019. Tissue‐resident innate immunity in the lung. Immunology imm.13143. https://doi.org/10.1111/imm.13143

Ardain, A., Porterfield, J. Z., Kløverpris, H. N., & Leslie, A. (2019). Type 3 ILCs in Lung Disease. Frontiers in Immunology, 10. https://doi.org/10.3389/fimmu.2019.00092

Baisley, K., Seeley, J., Siedner, M., Koole, K., Matthews, P., Tanser, F., …, Shahmanesh, M. (2019). Findings from home‐based HIV testing and facilitated linkage after scale‐up of test and treat in rural South Africa: Young people still missing. HIV Medicine, hiv.12787. https://doi.org/10.1111/hiv.12787

Barnhart, D. A., Harling, G., Muya, A., Ortblad, K. F., Mashasi, I., Dambach, P., … Spiegelman, D. (2019). Structural, interpersonal, psychosocial, and behavioral risk factors for HIV acquisition among female bar workers in Dar es Salaam, Tanzania. AIDS Care, 1–10. https://doi.org/10.1080/09540121.2019.1612018

Barteit, S., Guzek, D., Jahn, A., Bärnighausen, T., Jorge, M. M., & Neuhann, F. (2019). Evaluation of e-learning for medical education in low- and middle-income countries: A systematic review. Computers & Education, 103726. https://doi.org/10.1016/j.compedu.2019.103726

Barteit, S., Jahn, A., Banda, S. S., Bärnighausen, T., Bowa, A., Chileshe, G., … Neuhann, F. (2019). E-Learning for Medical Education in Sub-Saharan Africa and Low-Resource Settings: Viewpoint. Journal of Medical Internet Research, 21(1), e12449. https://doi.org/10.2196/12449

Barteit, S., Neuhann, F., Bärnighausen, T., Lüders, S., Malunga, G., Chileshe, G., … Jahn, A. (2019). Perspectives of Nonphysician Clinical Students and Medical Lecturers on Tablet-Based Health Care Practice Support for Medical Education in Zambia, Africa: Qualitative Study. JMIR MHealth and UHealth, 7(1), e12637. https://doi.org/10.2196/12637

Barton, J. P., Rajkoomar, E., Mann, J. K., Murakowski, D. K., Toyoda, M., Mahiti, M., … Ndung’u, T. (2019). Modelling and in vitro testing of the HIV-1 Nef fitness landscape. Virus Evolution, 5(2), vez029–vez029. https://doi.org/10.1093/ve/vez029

Baschieri, A., Gordeev, V. S., Akuze, J., Kwesiga, D., Blencowe, H., Cousens, S., … Lawn, J. E. (2019). “Every Newborn-INDEPTH” (EN-INDEPTH) study protocol for a randomised comparison of household survey modules for measuring stillbirths and neonatal deaths in five Health and Demographic Surveillance sites. Journal of Global Health, 9(1). https://doi.org/10.7189/jogh.09.010901

Bekker, L.-G., Tatoud, R., Dabis, F., Feinberg, M., Kaleebu, P., Marovich, M., … Johnston, M. I. (2019). The complex challenges of HIV vaccine development require renewed and expanded global commitment. The Lancet, S0140673619326820. https://doi.org/10.1016/S0140-6736(19)32682-0

Birdthistle, I., Tanton, C., Tomita, A., Graaf, K. de, Schaffnit, S. B., Tanser, F., & Slaymaker, E. (2019). Recent levels and trends in HIV incidence rates among adolescent girls and young women in ten high-prevalence African countries: A systematic review and meta-analysis. The Lancet Global Health, 7(11), e1521–e1540. https://doi.org/10.1016/S2214-109X(19)30410-3

Bixby, H., Bentham, J., Zhou, B., Di Cesare, M., Paciorek, C. J., Bennett, J. E., …Gareta,D.,..Tanser,F.,.. NCD Risk Factor Collaboration (NCD-RisC). (2019). Rising rural body-mass index is the main driver of the global obesity epidemic in adults. Nature, 569(7755), 260–264. https://doi.org/10.1038/s41586-019-1171-x

Chimukangara, B., Lessells, R. J., Rhee, S.-Y., Giandhari, J., Kharsany, A. B. M., Naidoo, K., … de Oliveira, T. (2019). Trends in Pretreatment HIV-1 Drug Resistance in Antiretroviral Therapy-naive Adults in South Africa, 2000–2016: A Pooled Sequence Analysis. EClinicalMedicine. https://doi.org/10.1016/j.eclinm.2019.03.006

Closson, K., Dietrich, J. J., Beksinska, M., Gibbs, A., Hornschuh, S., Smith, T., … Kaida, A. (2019). Measuring sexual relationship power equity among young women and young men South Africa: Implications for gender-transformative programming. PLOS ONE, 14(9), e0221554. https://doi.org/10.1371/journal.pone.0221554

Concannon, D., Herbst, K., & Manley, E. (2019). Developing a Data Dashboard Framework for Population Health Surveillance: Widening Access to Clinical Trial Findings. JMIR Formative Research, 3(2), e11342. https://doi.org/10.2196/11342

Cromarty, R., Sigal, A., Liebenberg, L. J. P., McKinnon, L. R., Abdool Karim, S. S., Passmore, J.-A. S., & Archary, D. (2019). Diminished HIV Infection of Target CD4+ T Cells in a Toll-Like Receptor 4 Stimulated in vitro Model. Frontiers in Immunology, 10, 1705. https://doi.org/10.3389/fimmu.2019.01705

Cuadros, D. F., Li, J., Mukandavire, Z., Musuka, G. N., Branscum, A. J., Sartorius, B., … Tanser, F. (2019). Towards UNAIDS Fast-Track goals: targeting priority geographic areas for HIV prevention and care in Zimbabwe. AIDS, 33(2), 305–314. https://doi.org/10.1097/QAD.0000000000002052

Cuadros, D. F., Sartorius, B., Hall, C., Akullian, A., Bärnighausen, T., & Tanser, F. (2018). Capturing the spatial variability of HIV epidemics in South Africa and Tanzania using routine healthcare facility data. International Journal of Health Geographics, 17(1). https://doi.org/10.1186/s12942-018-0146-8

Cuadros, D. F., Tomita, A., Vandormael, A., Slotow, R., Burns, J. K., & Tanser, F. (2019). Spatial structure of depression in South Africa: A longitudinal panel survey of a nationally representative sample of households. Scientific Reports, 9(1). https://doi.org/10.1038/s41598-018-37791-1

De Neve, J., Karlsson, O., Canavan, C.R., Chukwu, A., Adu‐Afarwuah, S., Bukenya, J., Darling, A.M., Harling, G., Moshabela, M., Killewo, J., Fink, G., Fawzi, W.W., Berhane, Y., 2019. Are out‐of‐school adolescents at higher risk of adverse health outcomes? Evidence from 9 diverse settings in sub‐Saharan Africa. Trop Med Int Health tmi.13328. https://doi.org/10.1111/tmi.13328

Desmond, C., Seeley, J., Groenewald, C., Ngwenya, N., Rich, K., & Barnett, T. (2019). Interpreting social determinants: Emergent properties and adolescent risk behaviour. PLOS ONE, 14(12), e0226241. https://doi.org/10.1371/journal.pone.0226241

Desmond, C., Viviers, A., Edward, T., Rich, K., Martin, P., & Richter, L. (2019). Priority-setting in the roll out of South Africa’s National Integrated ECD Policy. Early Years, 39(3), 276–294. https://doi.org/10.1080/09575146.2019.1572074

Di Tanna, G. L., Raza Khaki, A., Theron, G., McCarthy, K., Cox, H., Mupfumi, L., … Metcalfe, J. Z. (2019). Effect of Xpert MTB/RIF on clinical outcomes in routine care settings: individual patient data meta-analysis. The Lancet Global Health, 7(2), e191–e199. https://doi.org/10.1016/S2214-109X(18)30458-3

Dobra, A., Bärnighausen, T., Vandormael, A., & Tanser, F. (2019). A method for statistical analysis of repeated residential movements to link human mobility and HIV acquisition. PLOS ONE, 14(6), e0217284. https://doi.org/10.1371/journal.pone.0217284

Doyle, A. M., Mchunu, L., Koole, O., Mthembu, S., Dlamini, S., Ngwenya, N., … Seeley, J. (2019). Primary healthcare and school health service utilisation by adolescents and young adults in KwaZulu-Natal, South Africa. BMC Health Services Research, 19(1), 905. https://doi.org/10.1186/s12913-019-4559-2

Draper, C. E., Tomaz, S. A., Zihindula, G., Bunn, C., Gray, C. M., Hunt, K., … Wyke, S. (2019). Development, feasibility, acceptability and potential effectiveness of a healthy lifestyle programme delivered in churches in urban and rural South Africa. PloS One, 14(7), e0219787–e0219787. https://doi.org/10.1371/journal.pone.0219787

Dzomba, A., Tomita, A., Govender, K., & Tanser, F. (2019). Effects of Migration on Risky Sexual Behavior and HIV Acquisition in South Africa: A Systematic Review and Meta-analysis, 2000-2017. Aids and Behavior, 23(6), 1396–1430. https://doi.org/10.1007/s10461-018-2367-z

Dzomba, A., Tomita, A., Vandormael, A., Govender, K., & Tanser, F. (2019). Effect of ART scale-up and female migration intensity on risk of HIV acquisition: results from a population-based cohort in KwaZulu-Natal, South Africa. BMC Public Health, 19(1). https://doi.org/10.1186/s12889-019-6494-x

Elliott, T., Sanders, E. J., Doherty, M., Ndung’u, T., Cohen, M., Patel, P., Cairns, G., Rutstein, S. E., Ananworanich, J., Brown, C., & Fidler, S. (2019). Challenges of HIV diagnosis and management in the context of pre‐exposure prophylaxis (PrEP), post‐exposure prophylaxis (PEP), test and start and acute HIV infection: A scoping review. Journal of the International AIDS Society, 22(12). https://doi.org/10.1002/jia2.25419

Fakey Khan, D., Suleman, M., Baijnath, P., Perumal, R., Moodley, V., Mhlane, Z., … Wong, E. B. (2019). Multiple microbiologic tests for tuberculosis improve diagnostic yield of bronchoscopy in medically complex patients. AAS Open Research, 2, 25. https://doi.org/10.12688/aasopenres.12980.1

Feigin, V. L., Nichols, E., Alam, T., Bannick, M. S., Beghi, E., Blake, N., … Vos, T. (2019). Global, regional, and national burden of neurological disorders, 1990–2016: A systematic analysis for the Global Burden of Disease Study 2016. The Lancet Neurology, 18(5), 459–480. https://doi.org/10.1016/S1474-4422(18)30499-X

Frank, T. D., Carter, A., Jahagirdar, D., Biehl, M. H., Douwes-Schultz, D., Larson, S. L., … Murray, C. J. L. (2019). Global, regional, and national incidence, prevalence, and mortality of HIV, 1980–2017, and forecasts to 2030, for 195 countries and territories: A systematic analysis for the Global Burden of Diseases, Injuries, and Risk Factors Study 2017. The Lancet HIV, S2352301819301961. https://doi.org/10.1016/S2352-3018(19)30196-1

Geldsetzer, P., Manne-Goehler, J., Marcus, M.-E., Ebert, C., Zhumadilov, Z., Wesseh, C. S., … Jaacks, L. M. (2019). The state of hypertension care in 44 low-income and middle-income countries: A cross-sectional study of nationally representative individual-level data from 1·1 million adults. The Lancet. https://doi.org/10.1016/S0140-6736(19)30955-9

George, S., & McGrath, N. (2019). Social support, disclosure and stigma and the association with non-adherence in the six months after antiretroviral therapy initiation among a cohort of HIV-positive adults in rural KwaZulu-Natal, South Africa*. Aids Care-Psychological and Socio-Medical Aspects of Aids/Hiv, 31(7), 875–884. https://doi.org/10.1080/09540121.2018.1549720

Global Burden of Disease Cancer Collaboration, Fitzmaurice, C., Abate, D., Abbasi, N., Abbastabar, H., Abd-Allah, F., … Murray, C. J. L. (2019). Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017: A Systematic Analysis for the Global Burden of Disease Study. JAMA Oncology. https://doi.org/10.1001/jamaoncol.2019.2996

Gosset, A., Protopopescu, C., Larmarange, J., Orne-Gliemann, J., McGrath, N., Pillay, D., … Boyer, S. (2019). Retention in Care Trajectories of HIV-Positive Individuals Participating in a Universal Test-and-Treat Program in Rural South Africa (ANRS 12249 TasP Trial): JAIDS Journal of Acquired Immune Deficiency Syndromes, 80(4), 375–385. https://doi.org/10.1097/QAI.0000000000001938

Gregson, J., Rhee, S. Y., Datir, R., Pillay, D., Perno, C. F., Derache, A., … Gupta, R. K. (2019). HIV-1 viral load is elevated in individuals with reverse transcriptase mutation M184V/I during virological failure of first line antiretroviral therapy and is associated with compensatory mutation L74I. The Journal of Infectious Diseases, jiz631. https://doi.org/10.1093/infdis/jiz631

Gumede, D., Ngwenya, N. B., Namukwaya, S., Bernays, S., & Seeley, J. (2019). A reflection on ethical and methodological challenges of using separate interviews with adolescent-older carer dyads in rural South Africa. BMC Medical Ethics, 20(1), 47. https://doi.org/10.1186/s12910-019-0383-9

Gupta, R. K., Abdul-Jawad, S., McCoy, L. E., Mok, H. P., Peppa, D., Salgado, M., … Olavarria, E. (2019). HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation. Nature. https://doi.org/10.1038/s41586-019-1027-4

Hanifa, Y., Toro Silva, S., Karstaedt, A., Sahid, F., Charalambous, S., Chihota, V. N., … Grant, A. D. (2019). What causes symptoms suggestive of tuberculosis in HIV-positive people with negative initial investigations? The International Journal of Tuberculosis and Lung Disease. https://doi.org/10.5588/ijtld.18.0251

Harichund, C., Karim, Q. A., Kunene, P., Simelane, S., & Moshabela, M. (2019). Exploring factors that influence the integration of HIVST with HCT using a qualitative comparative cross-over design in KwaZulu-Natal, South Africa. Global Public Health, 14(9), 1275–1287. https://doi.org/10.1080/17441692.2019.1587638

Harling, G., Chanda, M. M., Ortblad, K. F., Mwale, M., Chongo, S., Kanchele, C., … Oldenburg, C. E. (2019). The influence of interviewers on survey responses among female sex workers in Zambia. BMC Medical Research Methodology, 19(1). https://doi.org/10.1186/s12874-019-0703-2

Harling, G., Muya, A., Ortblad, K. F., Mashasi, I., Dambach, P., Ulenga, N., … Spiegelman, D. (2019). HIV risk and pre-exposure prophylaxis interest among female bar workers in Dar es Salaam: cross-sectional survey. BMJ Open, 9(3), e023272. https://doi.org/10.1136/bmjopen-2018-023272

Houle, B., Rochat, T. J., Newell, M.-L., Stein, A., & Bland, R. M. (2019). Breastfeeding, HIV exposure, childhood obesity, and prehypertension: A South African cohort study. PLOS Medicine, 16(8), e1002889. https://doi.org/10.1371/journal.pmed.1002889

Inzaule, S. C., Hamers, R. L., Bertagnolio, S., Siedner, M. J., Rinke de Wit, T. F., & Gupta, R. K. (2019). Pretreatment HIV drug resistance in low- and middle-income countries. Future Virology, 14(6), 427–440. https://doi.org/10.2217/fvl-2018-0208

Khan, P. Y., Yates, T. A., Osman, M., Warren, R. M., van der Heijden, Y., Padayatchi, N., … Pym, A. (2019). Transmission of drug-resistant tuberculosis in HIV-endemic settings. The Lancet Infectious Diseases, 19(3), e77–e88. https://doi.org/10.1016/S1473-3099(18)30537-1

Larmarange, J., Diallo, M. H., McGrath, N., Iwuji, C., Plazy, M., Thiébaut, R., … Hontelez, J. (2019). Temporal trends of population viral suppression in the context of Universal Test and Treat: The ANRS 12249 TasP trial in rural South Africa. Journal of the International AIDS Society, 22(10). https://doi.org/10.1002/jia2.25402

Lee, G. Q., Reddy, K., Einkauf, K. B., Gounder, K., Chevalier, J. M., Dong, K. L., … Lichterfeld, M. (2019). HIV-1 DNA sequence diversity and evolution during acute subtype C infection. Nature Communications, 10(1), 2737. https://doi.org/10.1038/s41467-019-10659-2

Manne-Goehler, J., Geldsetzer, P., Agoudavi, K., Andall-Brereton, G., Aryal, K. K., Bicaba, B. W., … Jaacks, L. M. (2019). Health system performance for people with diabetes in 28 low- and middle-income countries: A cross-sectional study of nationally representative surveys. PLOS Medicine, 16(3), e1002751. https://doi.org/10.1371/journal.pmed.1002751

Manne‐Goehler, J., Siedner, M. J., Montana, L., Harling, G., Geldsetzer, P., Rohr, J., … Bärnighausen, T. W. (2019). Hypertension and diabetes control along the HIV care cascade in rural South Africa. Journal of the International AIDS Society, 22(3), e25213. https://doi.org/10.1002/jia2.25213

Mannell, J., Willan, S., Shahmanesh, M., Seeley, J., Sherr, L., & Gibbs, A. (2019). Why interventions to prevent intimate partner violence and HIV have failed young women in southern Africa. Journal of the International AIDS Society, 22(8), e25380. https://doi.org/10.1002/jia2.25380

Mathenjwa, T., Kim, H.-Y., Zuma, T., Shahmanesh, M., Seeley, J., Matthews, P., … Tanser, F. (2019). Home-based intervention to test and start (HITS) protocol: A cluster-randomized controlled trial to reduce HIV-related mortality in men and HIV incidence in women through increased coverage of HIV treatment. BMC Public Health, 19(1), 969. https://doi.org/10.1186/s12889-019-7277-0

Millar, J. R., Mvo, Z., Bengu, N., Fillis, R., Sprenger, K., Matthews, P. C., … Goulder, P. (2019). Increasing Diagnostic Uncertainties in Children With In Utero HIV Infection: The Pediatric Infectious Disease Journal, 1. https://doi.org/10.1097/INF.0000000000002315

Millard, J. D., Mackay, E. A., Bonnett, L. J., & Davies, G. R. (2019). The impact of inclusion, dose and duration of pyrazinamide (PZA) on efficacy and safety outcomes in tuberculosis: Systematic review and meta-analysis protocol. Systematic Reviews, 8(1), 329. https://doi.org/10.1186/s13643-019-1231-1

Muenchhoff, M., Adland, E., Roider, J., Kløverpris, H., Leslie, A., Boehm, S., … Goulder, P. J. R. (2019). Differential Pathogen-Specific Immune Reconstitution in Antiretroviral Therapy-Treated Human Immunodeficiency Virus-Infected Children. The Journal of Infectious Diseases. https://doi.org/10.1093/infdis/jiy668

Naidoo, A., Chirehwa, M., Ramsuran, V., McIlleron, H., Naidoo, K., Yende-Zuma, N., … Padayatchi, N. (2019). Effects of genetic variability on rifampicin and isoniazid pharmacokinetics in South African patients with recurrent tuberculosis. Pharmacogenomics, 20(4), 225–240. https://doi.org/10.2217/pgs-2018-0166

Naidoo, K. K., Ngubane, A., Gaza, P., Moodley, A., Ndung’u, T., & Thobakgale, C. F. (2019). Neutrophil Effector Functions Are Not Impaired in Duffy Antigen Receptor for Chemokines (DARC)-Null Black South Africans. Frontiers in Immunology, 10, 551. https://doi.org/10.3389/fimmu.2019.00551

Naidoo, K., Adeagbo, O., & Pleaner, M. (2019). Sexual and Reproductive Health Needs of Adolescent Girls and Young Women in Sub-Saharan Africa: Research, Policy, and Practice. SAGE Open, 9(3), 215824401985995. https://doi.org/10.1177/2158244019859951

Naidoo, L., Mzobe, Z., Jin, S. W., Rajkoomar, E., Reddy, T., Brockman, M. A., … Mann, J. K. (2019). Nef-mediated inhibition of NFAT following TCR stimulation differs between HIV-1 subtypes. Virology. https://doi.org/10.1016/j.virol.2019.02.011

Ndung’u, T., McCune, J. M., & Deeks, S. G. (2019). Why and where an HIV cure is needed and how it might be achieved. Nature, 576(7787), 397–405. https://doi.org/10.1038/s41586-019-1841-8

Ngwenya, N., Ambler, J., & Archary, M. (2019). Qualitative situational analysis of palliative care for adolescents with cancer and HIV in South Africa: Healthcare worker perceptions. Bmj Open, 9(1), e023225. https://doi.org/10.1136/bmjopen-2018-023225

Nimmo, C., Shaw, L. P., Doyle, R., Williams, R., Brien, K., Burgess, C., … Pym, A. S. (2019). Correction to: Whole genome sequencing Mycobacterium tuberculosis directly from sputum identifies more genetic diversity than sequencing from culture. BMC Genomics, 20(1), 433. https://doi.org/10.1186/s12864-019-5841-8

Nkosi, B., Seeley, J., Ngwenya, N., Mchunu, S. L., Gumede, D., Ferguson, J., & Doyle, A. M. (2019). Exploring adolescents and young people’s candidacy for utilising health services in a rural district, South Africa. BMC Health Services Research, 19(1). https://doi.org/10.1186/s12913-019-3960-1

O’Donnell, M. R., Larsen, M. H., Brown, T. S., Jain, P., Munsamy, V., Wolf, A., … Pym, A. (2019). Early detection of emergent extensively drug resistant tuberculosis (XDR-TB) by flow cytometry-based phenotyping and whole genome sequencing. Antimicrobial Agents and Chemotherapy. https://doi.org/10.1128/AAC.01834-18

Ogongo, P., Porterfield, J. Z., & Leslie, A. (2019). Lung Tissue Resident Memory T-Cells in the Immune Response to Mycobacterium tuberculosis. Frontiers in Immunology, 10, 992. https://doi.org/10.3389/fimmu.2019.00992

Ortblad, K. F., Harling, G., Chimbindi, N., Tanser, F., Salomon, J. A., & Bärnighausen, T. (2019). Does Incident Circumcision Lead to Risk Compensation? Evidence From a Population Cohort in KwaZulu-Natal, South Africa: JAIDS Journal of Acquired Immune Deficiency Syndromes, 80(3), 269–275. https://doi.org/10.1097/QAI.0000000000001912

Ortblad, K. F., Kibuuka Musoke, D., Ngabirano, T., Nakitende, A., Harling, G., Haberer, J. E., … Bärnighausen, T. (2019). The Effect of HIV Self-Testing Delivery Models on Female Sex Workers’ Sexual Behaviors: A Randomized Controlled Trial in Urban Uganda. AIDS and Behavior. https://doi.org/10.1007/s10461-019-02393-z

Osetinsky, B., Hontelez, J. A. C., Lurie, M. N., McGarvey, S. T., Bloomfield, G. S., Pastakia, S. D., … Galárraga, O. (2019). Epidemiological And Health Systems Implications Of Evolving HIV And Hypertension In South Africa And Kenya. Health Affairs, 38(7), 1173–1181. https://doi.org/10.1377/hlthaff.2018.05287

PANGEA Consortium and Rakai Health Sciences Program, Ratmann, O., Grabowski, M. K., Hall, M., Golubchik, T., Wymant, C., … Fraser, C. (2019). Inferring HIV-1 transmission networks and sources of epidemic spread in Africa with deep-sequence phylogenetic analysis. Nature Communications, 10(1). https://doi.org/10.1038/s41467-019-09139-4

Patenaude, B. N., & Bärnighausen, T. (2019). Quality-adjusted life year weights and treatment bias: Theory and evidence from cognitive interviews. SAGE Open Medicine, 7, 205031211985698. https://doi.org/10.1177/2050312119856986

Phillips, A., Cambiano, V., Johnson, L., Nakagawa, F., Homan, R., Meyer-Rath, G., Rehle, T., Tanser, F., Moyo, S., Shahmanesh, M., Castor, D., Russell, E., Jamieson, L., Bansi-Matharu, L., Shroufi, A., Barnabas, R., Parikh, U. M., Mellors, J. W., & Revill, P. (2019). Potential impact and cost-effectiveness of condomless-sex-concentrated PrEP in KwaZulu-Natal accounting for drug resistance. The Journal of Infectious Diseases, jiz667. https://doi.org/10.1093/infdis/jiz667

Pillai, N., Foster, N., Hanifa, Y., Ndlovu, N., Fielding, K., Churchyard, G., … Vassall, A. (2019). Patient costs incurred by people living with HIV/AIDS prior to ART initiation in primary healthcare facilities in Gauteng, South Africa. PLOS ONE, 14(2), e0210622. https://doi.org/10.1371/journal.pone.0210622

Price, J., Willcox, M., Kabudula, C. W., Herbst, K., Hinton, L., Kahn, K., & Harnden, A. (2019). Care pathways during a child’s final illness in rural South Africa: Findings from a social autopsy study. PLOS ONE, 14(10), 1–17. https://doi.org/10.1371/journal.pone.0224284

Price, J., Willcox, M., Kabudula, C. W., Herbst, K., Kahn, K., & Harnden, A. (2019). Home deaths of children under 5 years in rural South Africa: a population‐based longitudinal study. Tropical Medicine & International Health, tmi.13239. https://doi.org/10.1111/tmi.13239

Quan, V., Toro-Silva, S., Sriruttan, C., Chetty, V., Chihota, V., Candfield, S., Vassall, A., Grant, A. D., Govender, N. P., & for GERMS-SA. (2019). Pathways to care and outcomes among hospitalised HIV-seropositive persons with cryptococcal meningitis in South Africa. PLOS ONE, 14(12), e0225742. https://doi.org/10.1371/journal.pone.0225742

Ramjee, G., Sartorius, B., Morris, N., Wand, H., Reddy, T., Yssel, J. D., & Tanser, F. (2019). A decade of sustained geographic spread of HIV infections among women in Durban, South Africa. BMC Infectious Diseases, 19(1), 500. https://doi.org/10.1186/s12879-019-4080-6

Reid, D., Shenoi, S., Singh, R., Wang, M., Patel, V., Das, R., … Bucala, R. (2019). Low Expression Macrophage Migration Inhibitory Factor (MIF) alleles and Tuberculosis in HIV infected South Africans. Cytokine: X, 100004. https://doi.org/10.1016/j.cytox.2019.100004

Rochat, T. J., Houle, B., Stein, A., Mitchell, J., & Bland, R. M. (2019). Maternal alcohol use and children’s emotional and cognitive outcomes in rural South Africa. Samj South African Medical Journal, 109(7), 526–534. https://doi.org/10.7196/SAMJ.2019.v109i6.13120

Rohr, J. K., Manne-Goehler, J., Gómez-Olivé, F. X., Wagner, R. G., Rosenberg, M., Geldsetzer, P., … Salomon, J. A. (2019). HIV treatment cascade for older adults in rural South Africa. Sexually Transmitted Infections, sextrans-2018-053925. https://doi.org/10.1136/sextrans-2018-053925

Roider, J., Ngoepe, A., Muenchhoff, M., Adland, E., Groll, A., Ndung’u, T., … Leslie, A. (2019). Increased Regulatory T-Cell Activity and Enhanced T-Cell Homeostatic Signaling in Slow Progressing HIV-infected Children. Frontiers in Immunology, 10. https://doi.org/10.3389/fimmu.2019.00213

Roider, J., Porterfield, J. Z., Ogongo, P., Muenchhoff, M., Adland, E., Groll, A., … Leslie, A. (2019). Plasma IL-5 but Not CXCL13 Correlates With Neutralization Breadth in HIV-Infected Children. Frontiers in Immunology, 10, 1497. https://doi.org/10.3389/fimmu.2019.01497

Rolland, M., McGrath, N., Tiendrebeogo, T., Larmarange, J., Pillay, D., Dabis, F., & Orne-Gliemann, J. (2019). No effect of test and treat on sexual behaviours at population level in rural South Africa: AIDS, 1. https://doi.org/10.1097/QAD.0000000000002104

Rossenkhan, R., Rolland, M., Labuschagne, J. P. L., Ferreira, R.-C., Magaret, C. A., Carpp, L. N., … Edlefsen, P. T. (2019). Combining Viral Genetics and Statistical Modeling to Improve HIV-1 Time-of-Infection Estimation towards Enhanced Vaccine Efficacy Assessment. Viruses-Basel, 11(7), 607. https://doi.org/10.3390/v11070607

Russell, S. L., Lamprecht, D. A., Mandizvo, T., Jones, T. T., Naidoo, V., Addicott, K. W., … Steyn, A. J. C. (2019). Compromised Metabolic Reprogramming Is an Early Indicator of CD8+ T Cell Dysfunction during Chronic Mycobacterium tuberculosis Infection. Cell Reports, 29(11), 3564-3579.e5. https://doi.org/10.1016/j.celrep.2019.11.034

Sié, A., Coulibaly, B., Adama, S., Ouermi, L., Dah, C., Tapsoba, C., … Oldenburg, C. E. (2019). Antibiotic Prescription Patterns among Children Younger than 5 Years in Nouna District, Burkina Faso. The American Journal of Tropical Medicine and Hygiene. https://doi.org/10.4269/ajtmh.18-0791

Siedner, M. J., Bwana, M. B., Asiimwe, S., Amanyire, G., Musinguzi, N., Castillo-Mancilla, J., … Wyatt, M. (2019). Timing of Antiretroviral Therapy and Systemic Inflammation in Sub-Saharan Africa: Results From the META Longitudinal Cohort Study. The Journal of Infectious Diseases, jiz259. https://doi.org/10.1093/infdis/jiz259

Siedner, M. J., Bwana, M. B., Asiimwe, S., Musinguzi, N., Castillo-Mancilla, J., Amanyire, G., … On behalf of the META Study Investigators. (2019). Inflammatory biomarkers prior to antiretroviral therapy as prognostic markers of 12-month mortality in South Africa and Uganda. AIDS, Publish Ahead of Print. Retrieved from https://journals.lww.com/aidsonline/Fulltext/publishahead/Inflammatory_biomarkers_prior_to_antiretroviral.96890.aspx

Ssekubugu, R., Renju, J., Zaba, B., Seeley, J., Bukenya, D., Ddaaki, W., … Wringe, A. (2019). “He was no longer listening to me”: A qualitative study in six Sub-Saharan African countries exploring next-of-kin perspectives on caring following the death of a relative from AIDS. AIDS Care, 31(6), 754–760. https://doi.org/10.1080/09540121.2018.1537467

Tomita, A., Smith, C. M., Lessells, R. J., Pym, A., Grant, A. D., de Oliveira, T., & Tanser, F. (2019). Space-time clustering of recently-diagnosed tuberculosis and impact of ART scale-up: Evidence from an HIV hyper-endemic rural South African population. Scientific Reports, 9(1), 10724. https://doi.org/10.1038/s41598-019-46455-7

Tomita, A., Vandormael, A., Bärnighausen, T., Phillips, A., Pillay, D., De Oliveira, T., & Tanser, F. (2019). Socio-behavioural and community predictors of unsuppressed viral load: multi-level results from a hyper-endemic rural South African population. AIDS, 1. https://doi.org/10.1097/QAD.0000000000002100

Vandormael, A., Akullian, A., Siedner, M., de Oliveira, T., Bärnighausen, T., & Tanser, F. (2019). Declines in HIV incidence among men and women in a South African population-based cohort. Nature Communications, 10(1), 5482. https://doi.org/10.1038/s41467-019-13473-y

Vandormael, A., Tanser, F., Cuadros, D., & Dobra, A. (2019). Estimating trends in the incidence rate with interval censored data and time-dependent covariates. Statistical Methods in Medical Research, 096228021982989. https://doi.org/10.1177/0962280219829892

Witham, M. D., Davies, J. I., Bärnighausen, T., Bountogo, M., Manne-Goehler, J., Payne, C. F., … Harling, G. (2019). Frailty and physical performance in the context of extreme poverty: A population-based study of older adults in rural Burkina Faso. Wellcome Open Research, 4, 135. https://doi.org/10.12688/wellcomeopenres.15455.1

Wong, E. B., Gold, M. C., Meermeier, E. W., Xulu, B. Z., Khuzwayo, S., Sullivan, Z. A., … Lewinsohn, D. M. (2019). TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis. Communications Biology, 2(1), 203. https://doi.org/10.1038/s42003-019-0442-2

Wood, C. S., Thomas, M. R., Budd, J., Mashamba-Thompson, T. P., Herbst, K., Pillay, D., … Stevens, M. M. (2019). Taking connected mobile-health diagnostics of infectious diseases to the field. Nature, 566(7745), 467–474. https://doi.org/10.1038/s41586-019-0956-2

Yang, Y., McKhann, A., Chen, S., Harling, G., & Onnela, J.-P. (2019). Efficient vaccination strategies for epidemic control using network information. Epidemics, 27, 115–122. https://doi.org/10.1016/j.epidem.2019.03.002

Zhang, Y., Bärnighausen, T., & Eyal, N. (2019). Appropriate Health Resource Rationing in a Non-Ideal World: JAIDS Journal of Acquired Immune Deficiency Syndromes, 1. https://doi.org/10.1097/QAI.0000000000002127

Zhang, Y., Bärnighausen, T., & Eyal, N. (2019). When Global ART Budgets Cannot Cover All Patients, Who Should Be Eligible?: JAIDS Journal of Acquired Immune Deficiency Syndromes, 1. https://doi.org/10.1097/QAI.0000000000002017

2018 Publications

Ahmed, S., Autrey, J., Katz, I. T., Fox, M. P., Rosen, S., Onoya, D., … Bor, J. (2018). Why do people living with HIV not initiate treatment? A systematic review of qualitative evidence from low- and middle-income countries. Social Science & Medicine. https://doi.org/10.1016/j.socscimed.2018.05.048

Attaf, M., Malik, A., Severinsen, M.C., Roider, J., Ogongo, P., Buus, S., Ndung’u, T., Leslie, A., Kløverpris, H.N., Matthews, P.C., Sewell, A.K., Goulder, P. (2018). Major TCR Repertoire Perturbation by Immunodominant HLA-B*44:03-Restricted CMV-Specific T Cells. Frontiers in Immunology, 9. https://doi.org/10.3389/fimmu.2018.02539

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Ramsuran, V., Naranbhai, V., Horowitz, A., Qi, Y., Martin, M. P., Yuki, Y., … Carrington, M. (2018). Elevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells. Science, 359(6371), 86–90. https://doi.org/10.1126/science.aam8825

Ray, P. C., Bayliss, T., Prosser, G. A., Harrison, J. R., Green, K., Soares de Melo, C., … Boshoff, H. I. M. (2018). 2-Mercapto-quinazolinones as inhibitors of NDH-2 and Mycobacterium tuberculosis: Structure-activity relationships, mechanism of action and ADME characterization. ACS Infectious Diseases. https://doi.org/10.1021/acsinfecdis.7b00275

Reddy, V. P., Chinta, K. C., Saini, V., Glasgow, J. N., Hull, T. D., Traylor, A., … Steyn, A. J. C. (2018). Ferritin H Deficiency in Myeloid Compartments Dysregulates Host Energy Metabolism and Increases Susceptibility to Mycobacterium tuberculosis Infection. Frontiers in Immunology, 9. https://doi.org/10.3389/fimmu.2018.00860

Rickman, H. M., Miller, R. F., Morris-Jones, S., Kellgren, L., Edwards, S. G., & Grant, A. D. (2018). Missed opportunities for tuberculosis prevention among patients accessing a UK HIV service. International Journal of STD & AIDS, 095646241877301. https://doi.org/10.1177/0956462418773010

Roider, J., Maehara, T., Ngoepe, A., Ramsuran, D., Muenchhoff, M., Adland, E., … Leslie, A. (2018). High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults. Frontiers in Immunology, 9. https://doi.org/10.3389/fimmu.2018.01975

Rosenberg, M. S., Gómez-Olivé, F. X., Rohr, J. K., Kahn, K., & Bärnighausen, T. W. (2018). Are circumcised men safer sex partners? Findings from the HAALSI cohort in rural South Africa. PLOS ONE, 13(8), e0201445. https://doi.org/10.1371/journal.pone.0201445

Seipone, I. D., Singh, R., Patel, V. B., Singh, A., Gordon, M. L., Muema, D. M., … Ndung’u, T. (2018). Tuberculous meningitis is associated with higher cerebrospinal HIV-1 viral loads compared to other HIV-1-associated meningitides. PLOS ONE, 13(2), e0192060. https://doi.org/10.1371/journal.pone.0192060

Sié, A., Porco, T. C., Dah, C., Lietman, T. M., Keenan, J. D., Ouermi, L., … Snyder, B. M. (2018). Effect of Antibiotics on Short-Term Growth among Children in Burkina Faso: A Randomized Trial. The American Journal of Tropical Medicine and Hygiene. https://doi.org/10.4269/ajtmh.18-0342

Siedner, M. J., & Triant, V. (2018). Undetectable = Untransmittable and Your Health: The personal benefits of early and continuous therapy for HIV infection. The Journal of Infectious Diseases. https://doi.org/10.1093/infdis/jiy445

Siedner, M. J., Baisley, K., Orne-Gliemann, J., Pillay, D., Koole, O., Wong, E. B., … Bachmann, M. (2018). Linkage to primary care after home-based blood pressure screening in rural KwaZulu-Natal, South Africa: a population-based cohort study. BMJ Open, 8(12), e023369. https://doi.org/10.1136/bmjopen-2018-023369

Smith, C. M., Lessells, R., Grant, A. D., Herbst, K., & Tanser, F. (2018). Spatial clustering of drug-resistant tuberculosis in Hlabisa subdistrict, KwaZulu-Natal, 2011–2015. The International Journal of Tuberculosis and Lung Disease, 22(3), 287–293. https://doi.org/10.5588/ijtld.17.0457

Sweeney, S., Mukora, R., Candfield, S., Guinness, L., Grant, A. D., & Vassall, A. (2018). Measuring income for catastrophic cost estimates: Limitations and policy implications of current approaches. Social Science & Medicine, 215, 7–15. https://doi.org/10.1016/j.socscimed.2018.08.041

Tanser, F., Azongo, D. K., Vandormael, A., Bärnighausen, T., & Appleton, C. (2018). Impact of the scale-up of piped water on urogenital schistosomiasis infection in rural South Africa. ELife, 7, e33065. https://doi.org/10.7554/eLife.33065

Tlou, B., Sartorius, B., & Tanser, F. (2018). Investigating risk factors for under-five mortality in an HIV hyper-endemic area of rural South Africa, from 2000-2014. PLOS ONE, 13(11), e0207294. https://doi.org/10.1371/journal.pone.0207294

Tlou, B., Sartorius, B., Tanser, F., 2018. Effect of timing of mother’s death on child survival in a rural HIV hyper-endemic South African population. BMC Public Health,18. https://doi.org/10.1186/s12889-018-6152-8

van der Heijden, Y. F., Karim, F., Chinappa, T., Mufamadi, G., Zako, L., Shepherd, B. E., … Pym, A. S. (2018). Older age at first tuberculosis diagnosis is associated with tuberculosis recurrence in HIV-negative persons. The International Journal of Tuberculosis and Lung Disease, 22(8), 871–877. https://doi.org/10.5588/ijtld.17.0766

Walker-Sperling, V., Ramsuran, V., Martin, M., Naranbhai, V., Li, H., Anderson, S. K., … Carrington, M. (2018). P069UTR SNPS rs111686073 and rs73410010 independently modify expression of tapasin in blacks. Human Immunology, 79, 113. https://doi.org/10.1016/j.humimm.2018.07.128

Wang, Z., Cumming, B. M., Mao, C., Zhu, Y., Lu, P., Steyn, A. J. C., … Hu, Y. (2018). RbpA and σ ^B association regulates polyphosphate levels to modulate mycobacterial isoniazid-tolerance: RbpA and σ ^B associate to regulate INH-tolerance. Molecular Microbiology. https://doi.org/10.1111/mmi.13952

Yoo, H., Lee, J., Yim, J.-J., Bärnighausen, T., Tanser, F., & Park, S. K. (2018). Effect of the Number of Pregnancies on Mortality Risk in HIV-Infected Women: a Prospective Cohort Study in Rural KwaZulu-Natal, South Africa. AIDS and Behavior. https://doi.org/10.1007/s10461-018-2232-0

Yoon, H. A., Nakouzi, A., Chang, C. C., Kuniholm, M. H., Carreño, L. J., Wang, T., … Pirofski, L. (2018). Association between plasma antibody responses and risk for Cryptococcus-associated immune reconstitution inflammatory syndrome. The Journal of Infectious Diseases. https://doi.org/10.1093/infdis/jiy447

2017 Publications

Aicken, C. R. H., Sutcliffe, L. J., Gibbs, J., Tickle, L. J., Hone, K., Harding-Esch, E. M., … Shahmanesh, M. (2017). Using the eSexual Health Clinic to access chlamydia treatment and care via the internet: a qualitative interview study. Sexually Transmitted Infections. https://doi.org/10.1136/sextrans-2017-053227

Akilimali, N. A., Chang, C. C., Muema, D. M., Reddy, T., Moosa, M.-Y. S., Lewin, S. R., … Ndung’u, T. (2017). Plasma But Not Cerebrospinal Fluid Interleukin 7 and Interleukin 5 Levels Pre–Antiretroviral Therapy Commencement Predict Cryptococcosis-Associated Immune Reconstitution Inflammatory Syndrome. Clinical Infectious Diseases, 65(9), 1551–1559. https://doi.org/10.1093/cid/cix598

Akullian, A., Bershteyn, A., Klein, D., Vandormael, A., Bärnighausen, T., & Tanser, F. (2017). Sexual partnership age pairings and risk of HIV acquisition in rural South Africa: AIDS, 31(12), 1755–1764. https://doi.org/10.1097/QAD.0000000000001553

Ambia, J., Renju, J., Wringe, A., Todd, J., Geubbels, E., Nakiyingi-Miiro, J., … Mee, P. (2017). From policy to practice: Exploring the implementation of antiretroviral therapy access and retention policies between 2013 and 2016 in six sub-Saharan African countries. Bmc Health Services Research, 17, 758. https://doi.org/10.1186/s12913-017-2678-1

Baernighausen, T., Oldenburg, C., Tugwell, P., Bommer, C., Ebert, C., Barreto, M., … Vollmer, S. (2017). Quasi-experimental study designs series-paper 7: Assessing the assumptions. Journal of Clinical Epidemiology, 89, 53–66. https://doi.org/10.1016/j.jclinepi.2017.02.017

Baernighausen, T., Rottingen, J.-A., Rockers, P., Shemilt, I., & Tugwell, P. (2017). Quasi-experimental study designs series-paper 1: Introduction: Two historical lineages. Journal of Clinical Epidemiology, 89, 4–11. https://doi.org/10.1016/j.jclinepi.2017.02.020

Baernighausen, T., Tugwell, P., Rottingen, J.-A., Shemilt, I., Rockers, P., Geldsetzer, P., … Atun, R. (2017). Quasi-experimental study designs series-paper 4: Uses and value. Journal of Clinical Epidemiology, 89, 21–29. https://doi.org/10.1016/j.jclinepi.2017.03.012

Baijnath, S., Moodley, C., Ngcobo, B., Singh, S. D., Kruger, H. G., Arvidsson, P. I., … Govender, T. (2017). Clofazimine protects against mycobacterium tuberculosis dissemination in the CNS following an aerosol challenge in a murine model. International Journal of Antimicrobial Agents. https://doi.org/10.1016/j.ijantimicag.2017.08.020

Bernays, S., Bukenya, D., Thompson, C., Ssembajja, F., & Seeley, J. (2017). Being an ‘adolescent’: The consequences of gendered risks for young people in rural Uganda. Childhood, 0907568217732119. https://doi.org/10.1177/0907568217732119

Bhattacharya, D., Danaviah, S., Muema, D. M., Akilimali, N. A., Moodley, P., Ndung’u, T., & Das, G. (2017). Cellular Architecture of Spinal Granulomas and the Immunological Response in Tuberculosis Patients Coinfected with HIV. Frontiers in Immunology, 8, 1120. https://doi.org/10.3389/fimmu.2017.01120

Bocquier, P., Ginsburg, C., Herbst, K., Sankoh, O., & Collinson, M. A. (2017). A training manual for event history data management using Health and Demographic Surveillance System data. BMC Research Notes, 10(1), 224–224. https://doi.org/10.1186/s13104-017-2541-9

Bohlius, J. (2017). Comparison of Kaposi sarcoma risk in HIV-positive adults across five continents: a multiregional multicohort study. Clinical Infectious Diseases. https://doi.org/10.1093/cid/cix480

Bor, J., Ahmed, S., Fox, M. P., Rosen, S., Meyer-Rath, G., Katz, I. T., … Bärnighausen, T. (2017). Effect of eliminating CD4-count thresholds on HIV treatment initiation in South Africa: An empirical modeling study. PLOS ONE, 12(6), e0178249. https://doi.org/10.1371/journal.pone.0178249

Bor, J., Chiu, C., Ahmed, S., Katz, I., Fox, M., Rosen, S., … Bärnighausen, T. (2017). Failure to initiate HIV treatment in patients with high CD4 counts: evidence from demographic surveillance in rural KwaZulu-Natal. Tropical Medicine & International Health, n/a-n/a. https://doi.org/10.1111/tmi.13013

Bor, J., Fox, M. P., Rosen, S., Venkataramani, A., Tanser, F., Pillay, D., & Bärnighausen, T. (2017). Treatment eligibility and retention in clinical HIV care: A regression discontinuity study in South Africa. PLOS Medicine, 14(11), e1002463. https://doi.org/10.1371/journal.pmed.1002463

Brennan, A. T., Davies, M.-A., Bor, J., Wandeler, G., Stinson, K., Wood, R., … Fox, M. P. (2017). Has the phasing out of stavudine in accordance with changes in WHO guidelines led to a decrease in single-drug substitutions in first-line antiretroviral therapy for HIV in sub-Saharan Africa? AIDS, 31(1). Retrieved from http://journals.lww.com/aidsonline/Fulltext/2017/01020/Has_the_phasing_out_of_stavudine_in_accordance.16.aspx

Bärnighausen, T. (2017). Population health intervention research: three important advancements. International Journal of Public Health. https://doi.org/10.1007/s00038-017-0985-2

Bukenya, D., Wringe, A., Moshabela, M., Skovdal, M., Ssekubugu, R., Paparini, S., … Seeley, J. (2017). Where are we now? A multicountry qualitative study to explore access to pre-antiretroviral care services: a precursor to antiretroviral therapy initiation. Sexually Transmitted Infections, 93(Suppl 3). https://doi.org/10.1136/sextrans-2016-052970

Chanda, M. M., Ortblad, K. F., Mwale, M., Chongo, S., Kanchele, C., Kamungoma, N., … Oldenburg, C. E. (2017). HIV self-testing among female sex workers in Zambia: A cluster randomized controlled trial. PLOS Medicine, 14(11), e1002442. https://doi.org/10.1371/journal.pmed.1002442

Chanda, M. M., Ortblad, K. F., Mwale, M., Chongo, S., Kanchele, C., Kamungoma, N., … Oldenburg, C. E. (2017). Contraceptive use and unplanned pregnancy among female sex workers in Zambia. Contraception, 96(3), 196–202. https://doi.org/10.1016/j.contraception.2017.07.003

Chang, C. C., Kangethe, R., Omarjee, S., Hiramen, K., Gosnell, B., Sojane, K., … Ndung’u, T. (2017). Relationship of Human Immunodeficiency Virus Viral Load in Cerebrospinal Fluid and Plasma in Patients Co-infected With Cryptococcal Meningitis. Open Forum Infectious Diseases, 4(2). https://doi.org/10.1093/ofid/ofx032

Collier, D., Iwuji, C., Derache, A., de Oliveira, T., Okesola, N., Calmy, A., … Gupta, R. K. (2017). Virological Outcomes of Second-line Protease Inhibitor–Based Treatment for Human Immunodeficiency Virus Type 1 in a High-Prevalence Rural South African Setting: A Competing-Risks Prospective Cohort Analysis. Clinical Infectious Diseases, 64(8), 1006–1016. https://doi.org/10.1093/cid/cix015

Cordes, J. L., Stangl, A., Krishnaratne, S., Hoddinott, G., Mathema, H., Bond, V., … Hargreaves, J. R. (2017). Trends in Responses to DHS Questions Should Not Be Interpreted as Reflecting an Increase in “Anticipated Stigma” in Africa: JAIDS Journal of Acquired Immune Deficiency Syndromes, 75(1), e22–e23. https://doi.org/10.1097/QAI.0000000000001328

Cornell, M., Johnson, L. F., Wood, R., Tanser, F., Fox, M. P., Prozesky, H., … Boulle, A. (2017). Twelve-year mortality in adults initiating antiretroviral therapy in South Africa. Journal of the International AIDS Society, 20(1). https://doi.org/10.7448/IAS.20.1.21902

Cox, H., Dickson-Hall, L., Ndjeka, N., van’t Hoog, A., Grant, A., Cobelens, F., … Nicol, M. (2017). Delays and loss to follow-up before treatment of drug-resistant tuberculosis following implementation of Xpert MTB/RIF in South Africa: A retrospective cohort study. PLOS Medicine, 14(2), e1002238. https://doi.org/10.1371/journal.pmed.1002238

Cuadros, D. F., Li, J., Branscum, A. J., Akullian, A., Jia, P., Mziray, E. N., & Tanser, F. (2017). Mapping the spatial variability of HIV infection in Sub-Saharan Africa: Effective information for localized HIV prevention and control. Scientific Reports, 7(1), 9093. https://doi.org/10.1038/s41598-017-09464-y

Cumming, B. M., Chinta, K. C., Reddy, V. P., & Steyn, A. J. C. (2017). Role of Ergothioneine in Microbial Physiology and Pathogenesis. Antioxidants & Redox Signaling. https://doi.org/10.1089/ars.2017.7300

Cumming, B. M., Rahman, M. A., Lamprecht, D. A., Rohde, K. H., Saini, V., Adamson, J. H., … Steyn, A. J. C. (2017). Mycobacterium tuberculosis arrests host cycle at the G1/S transition to establish long term infection. PLOS Pathogens, 13(5), e1006389. https://doi.org/10.1371/journal.ppat.1006389

De Neve, J.-W., & Harling, G. (2017). Offspring schooling associated with increased parental survival in rural KwaZulu-Natal, South Africa. Social Science & Medicine, 176, 149–157. https://doi.org/10.1016/j.socscimed.2017.01.015

de Welzen, L., Eldholm, V., Maharaj, K., Manson, A. L., Earl, A. M., & Pym, A. S. (2017). Whole transcriptome and genomic analysis of extensively drug-resistant Mycobacterium tuberculosis clinical isolates identifies downregulation of ethA as a mechanism of ethionamide resistance. Antimicrobial Agents and Chemotherapy. https://doi.org/10.1128/AAC.01461-17

Dobra, A., Bärnighausen, T., Vandormael, A., & Tanser, F. (2017). Space-time migration patterns and risk of HIV acquisition in rural South Africa. AIDS (London, England), 31(1), 137–145. https://doi.org/10.1097/QAD.0000000000001292

Dong, K. L., Moodley, A., Kwon, D. S., Ghebremichael, M. S., Dong, M., Ismail, N., … Ndung’u, T. (n.d.). Detection and treatment of Fiebig stage I HIV-1 infection in young at-risk women in South Africa: a prospective cohort study. The Lancet HIV. https://doi.org/10.1016/S2352-3018(17)30146-7

Dowdy, D. W., Grant, A. D., Dheda, K., Nardell, E., Fielding, K., & Moore, D. A. J. (2017). Designing and Evaluating Interventions to Halt the Transmission of Tuberculosis. The Journal of Infectious Diseases, 216(suppl_6), S654–S661. https://doi.org/10.1093/infdis/jix320

Gatuguta, A., Katusiime, B., Seeley, J., Colombini, M., Mwanzo, I., & Devries, K. (2017). Should community health workers offer support healthcare services to survivors of sexual violence? a systematic review. BMC International Health and Human Rights, 17(1), 28. https://doi.org/10.1186/s12914-017-0137-z

Geldsetzer, P., De Neve, J.-W., Boudreaux, C., Bärnighausen, T., & Bossert, T. J. (2017). Improving the performance of community health workers in Swaziland: findings from a qualitative study. Human Resources for Health, 15(1), 68. https://doi.org/10.1186/s12960-017-0236-x

Geldsetzer, P., Feigl, A. B., Tanser, F., Gareta, D., Pillay, D., & Bärnighausen, T. (2017). Population-level decline in BMI and systolic blood pressure following mass HIV treatment: Evidence from rural KwaZulu-Natal: Decline in BMI and BP following Mass HIV Treatment. Obesity, 25(1), 200–206. https://doi.org/10.1002/oby.21663

Godfrey, C., Thigpen, M. C., Crawford, K. W., Jean-Phillippe, P., Pillay, D., Persaud, D., … Fitzgibbon, J. (2017). Global HIV Antiretroviral Drug Resistance. The Journal of Infectious Diseases. https://doi.org/10.1093/infdis/jix137

Goodall, R. L., Dunn, D. T., Nkurunziza, P., Mugarura, L., Pattery, T., Munderi, P., … Gupta, R. K. (2017). Rapid accumulation of HIV-1 thymidine analogue mutations and phenotypic impact following prolonged viral failure on zidovudine-based first-line ART in sub-Saharan Africa. Journal of Antimicrobial Chemotherapy, 72(5), 1450–1455. https://doi.org/10.1093/jac/dkw583

Gupta, R. K., Gregson, J., Parkin, N., Haile-Selassie, H., Tanuri, A., Andrade Forero, L., … Bertagnolio, S. (2017). HIV-1 drug resistance before initiation or re-initiation of first-line antiretroviral therapy in low-income and middle-income countries: a systematic review and meta-regression analysis. The Lancet Infectious Diseases. https://doi.org/10.1016/S1473-3099(17)30702-8

Haber, N., Tanser, F., Bor, J., Naidu, K., Mutevedzi, T., Herbst, K., … Bärnighausen, T. (2017). From HIV infection to therapeutic response: a population-based longitudinal HIV cascade-of-care study in KwaZulu-Natal, South Africa. The Lancet HIV, 4(5), e223–e230. https://doi.org/10.1016/S2352-3018(16)30224-7

Hainsworth, E. G., Shahmanesh, M., & Stevenson, F. (2017). Exploring the views and experiences of HIV positive patients treated for cancer: a systematic review of the literature. AIDS Care, 1–9. https://doi.org/10.1080/09540121.2017.1381332

Hanifa, Y., Fielding, K. L., Chihota, V. N., Adonis, L., Charalambous, S., Foster, N., … Grant, A. D. (2017). A clinical scoring system to prioritise investigation for tuberculosis among adults attending HIV clinics in South Africa. PLOS ONE, 12(8), e0181519. https://doi.org/10.1371/journal.pone.0181519

Harling, G., Gumede, D., Mutevedzi, T., McGrath, N., Seeley, J., Pillay, D., … Herbst, A. J. (2017). The impact of self-interviews on response patterns for sensitive topics: a randomized trial of electronic delivery methods for a sexual behaviour questionnaire in rural South Africa. BMC Medical Research Methodology, 17(1), 125. https://doi.org/10.1186/s12874-017-0403-8

Harling, G., McGrath, N., Seeley, J., BBrnighausen, T. W., & Herbst, A. J. (2017). The Advantages and Disadvantages of Self-Interviews for Sensitive Topics: A Randomized Trial of Electronic Delivery Methods for a Sexual Behaviour Questionnaire in Rural South Africa. SSRN Electronic Journal. https://doi.org/10.2139/ssrn.2945424

Helova, A., Akama, E., Bukusi, E. A., Musoke, P., Nalwa, W. Z., Odeny, T. A., … Abuogi, L. L. (2017). Health facility challenges to the provision of Option B+ in western Kenya: a qualitative study. Health Policy Plan, 32.

Iwuji, C. C., Orne-Gliemann, J., Larmarange, J., Balestre, E., Thiebaut, R., Tanser, F., … Rekacewicz, C. (2017). Universal test and treat and the HIV epidemic in rural South Africa: a phase 4, open-label, community cluster randomised trial. The Lancet HIV. https://doi.org/10.1016/S2352-3018(17)30205-9

Iwuji, C., & Newell, M.-L. (2017a). HIV testing: The “front door” to the UNAIDS 90-90-90 target. Public Health Action, 7(2), 79–79. https://doi.org/10.5588/ijtld.17.0046

Iwuji, C., & Newell, M.-L. (2017b). Towards control of the global HIV epidemic: Addressing the middle-90 challenge in the UNAIDS 90-90-90 target. Plos Medicine, 14(5), e1002293. https://doi.org/10.1371/journal.pmed.1002293

Jackson, L., Hunter, J., Cele, S., Ferreira, I. M., Young, A., Karim, F., … Sigal, A. (2017). Incomplete inhibition of HIV infection results in more HIV infected lymph node cells by reducing cell death. https://doi.org/10.1101/163352

Jardim, T. V., Reiger, S., Abrahams-Gessel, S., Gomez-Olive, F. X., Wagner, R. G., Wade, A., … Gaziano, T. A. (2017). Hypertension management in a population of older adults in rural South Africa: Journal of Hypertension, 35(6), 1283–1289. https://doi.org/10.1097/HJH.0000000000001312

Karat, A. S., Tlali, M., Fielding, K. L., Charalambous, S., Chihota, V. N., Churchyard, G. J., … Grant, A. D. (2017). Measuring mortality due to HIV-associated tuberculosis among adults in South Africa: Comparing verbal autopsy, minimally-invasive autopsy, and research data. PLOS ONE, 12(3), e0174097. https://doi.org/10.1371/journal.pone.0174097

Kaufmann, S. H. E., Dockrell, H. M., Drager, N., Ho, M. M., McShane, H., Neyrolles, O., … Hogarth, P. (2017). TBVAC2020: Advancing Tuberculosis Vaccines from Discovery to Clinical Development. Frontiers in Immunology, 8, 1203. https://doi.org/10.3389/fimmu.2017.01203

Kiguoya, M. W., Mann, J. K., Chopera, D., Gounder, K., Lee, G. Q., Hunt, P. W., … Ndung’u, T. (2017). Subtype-Specific Differences in Gag-Protease-Driven Replication Capacity Are Consistent with Intersubtype Differences in HIV-1 Disease Progression. Journal of Virology, 91(13), e00253-17. https://doi.org/10.1128/JVI.00253-17

Kiwuwa-Muyingo, S., Nazziwa, J., Ssemwanga, D., Ilmonen, P., Njai, H., Ndembi, N., … Kaleebu, P. (2017). HIV-1 transmission networks in high risk fishing communities on the shores of Lake Victoria in Uganda: A phylogenetic and epidemiological approach. PLOS ONE, 12(10), e0185818. https://doi.org/10.1371/journal.pone.0185818

Kugathasan, R., Collier, D. A., Haddow, L. J., El Bouzidi, K., Edwards, S. G., Cartledge, J. D., … Gupta, R. K. (2017). Diffuse White Matter Signal Abnormalities on Magnetic Resonance Imaging Are Associated With Human Immunodeficiency Virus Type 1 Viral Escape in the Central Nervous System Among Patients With Neurological Symptoms. Clinical Infectious Diseases, 64(8), 1059–1065. https://doi.org/10.1093/cid/cix035

Laher, F., Ranasinghe, S., Porichis, F., Mewalal, N., Pretorius, K., Ismail, N., … Ndhlovu, Z. M. (2017). HIV Controllers Exhibit Enhanced Frequencies of Major Histocompatibility Complex Class II Tetramer ⁺ Gag-Specific CD4 ⁺ T Cells in Chronic Clade C HIV-1 Infection. Journal of Virology, 91(7), e02477-16. https://doi.org/10.1128/JVI.02477-16

Lampejo, T., Bruce, M., Teall, A., Dall’Antonia, M., Crawley-Boevey, E., Grant, P., … Nastouli, E. (2017). Caring for a patient with rabies: implications of the Milwaukee protocol for infection control and public health measures. Journal of Hospital Infection, 96(4), 385–391. https://doi.org/10.1016/j.jhin.2017.04.018

Lavis, J. N., Baernighausen, T., & El-Jardali, F. (2017). Quasi-experimental study designs series-paper 11: Supporting the production and use of health systems research syntheses that draw on quasi-experimental study designs. Journal of Clinical Epidemiology, 89, 92–97. https://doi.org/10.1016/j.jclinepi.2017.03.014

Lee, G. Q., Orlova-Fink, N., Einkauf, K., Chowdhury, F. Z., Sun, X., Harrington, S., … Lichterfeld, M. (2017). Clonal expansion of genome-intact HIV-1 in functionally polarized Th1 CD4+ T cells. Journal of Clinical Investigation, 127(7), 2689–2696. https://doi.org/10.1172/JCI93289

Lessells, R. J., Cooke, G. S., McGrath, N., Nicol, M. P., Newell, M.-L., & Godfrey-Faussett, P. (2017). Impact of Point-of-care Xpert MTB/RIF on Tuberculosis Treatment Initiation: A Cluster Randomised Trial. American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/rccm.201702-0278OC

Lewis, J., Payne, H., Walker, A. S., Otwombe, K., Gibb, D. M., Babiker, A. G., … Callard, R. E. (2017). Thymic Output and CD4 T-Cell Reconstitution in HIV-Infected Children on Early and Interrupted Antiretroviral Treatment: Evidence from the Children with HIV Early Antiretroviral Therapy Trial. Frontiers in Immunology, 8, 1162. https://doi.org/10.3389/fimmu.2017.01162

Mabuka, J. M., Dugast, A.-S., Muema, D. M., Reddy, T., Ramlakhan, Y., Euler, Z., … Ndung’u, T. (2017). Plasma CXCL13 but Not B Cell Frequencies in Acute HIV Infection Predicts Emergence of Cross-Neutralizing Antibodies. Frontiers in Immunology, 8, 1104. https://doi.org/10.3389/fimmu.2017.01104

Mahamed, D., Boulle, M., Ganga, Y., Mc Arthur, C., Skroch, S., Oom, L., … Sigal, A. (2017). Intracellular growth of Mycobacterium tuberculosis after macrophage cell death leads to serial killing of host cells. ELife, 6. https://doi.org/10.7554/eLife.22028

Maheu-Giroux, M., Tanser, F., Boily, M.-C., Pillay, D., Joseph, S. A., & Bärnighausen, T. (2017a). Determinants of time from HIV infection to linkage-to-care in rural KwaZulu-Natal, South Africa: AIDS, 31(7), 1017–1024. https://doi.org/10.1097/QAD.0000000000001435

Maheu-Giroux, M., Tanser, F., Boily, M.-C., Pillay, D., Joseph, S. A., & Bärnighausen, T. (2017b). Determinants of time from HIV infection to linkage-to-care in rural KwaZulu-Natal, South Africa: AIDS, 31(7), 1017–1024. https://doi.org/10.1097/QAD.0000000000001435

Malik, A., Adland, E., Laker, L., Kløverpris, H., Fardoos, R., Roider, J., … Goulder, P. J. R. (2017). Immunodominant cytomegalovirus-specific CD8+ T-cell responses in sub-Saharan African populations. PLOS ONE, 12(12), e0189612. https://doi.org/10.1371/journal.pone.0189612

Manne-Goehler, J., Siedner, M., Geldsetzer, P., Harling, G., Montana, L., Rohr, J., … Barnighausen, T. (2017). Leveraging the ART Advantage: diabetes and hypertension along the HIV care cascade in rural South Africa. Open Forum Infectious Diseases, 4(suppl_1), S58–S58. https://doi.org/10.1093/ofid/ofx162.137

Manson, A. L., Cohen, K. A., Abeel, T., Desjardins, C. A., Armstrong, D. T., Barry III, C. E., … Earl, A. M. (2017). Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance. Nat Genet, 49(3), 395–402.

Maskew, M., Bor, J., Hendrickson, C., MacLeod, W., Bärnighausen, T., Pillay, D., … Fox, M. P. (2017). Imputing HIV treatment start dates from routine laboratory data in South Africa: a validation study. BMC Health Services Research, 17(1), 41. https://doi.org/10.1186/s12913-016-1940-2

McGrath, N., & Grapsa, E. (2017). Does antiretroviral therapy change partnership dynamics and HIV risk behaviours among HIV-infected adults. Aids, 31(10), 1451–1460. https://doi.org/10.1097/QAD.0000000000001502

Mitchell, J. M., Tomlinson, M., Bland, R. M., Houle, B., Stein, A., & Rochat, T. J. (2017). Confirmatory factor analysis of the Kaufman assessment battery in a sample of primary school-aged children in rural South Africa. South African Journal of Psychology, 0081246317741822. https://doi.org/10.1177/0081246317741822

Mkwanazi, N. B., Rochat, T. J., & Bland, R. M. (2017). The Amagugu intervention: a qualitative investigation into maternal experiences and perspectives of a maternal HIV disclosure support intervention in rural South Africa. Health Policy and Planning, 32(9), 1231–1240. https://doi.org/10.1093/heapol/czx056

Mlcochova, P., Caswell, S. J., Taylor, I. A., Towers, G. J., & Gupta, R. K. (2017). DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV-1 infection of macrophages. The EMBO Journal, e201796880. https://doi.org/10.15252/embj.201796880

Mlcochova, P., Sutherland, K. A., Watters, S. A., Bertoli, C., de Bruin, R. A., Rehwinkel, J., … Gupta, R. K. (2017). A G1?like state allows HIV?1 to bypass SAMHD1 restriction in macrophages. The EMBO Journal, 36(5), 604–616. https://doi.org/10.15252/embj.201696025

Moosa, A., Lamprecht, D. A., Arora, K., Barry, C. E., Boshoff, H. I. M., Ioerger, T. R., … Warner, D. F. (2017). Susceptibility of Mycobacterium tuberculosis Cytochrome bd Oxidase Mutants to Compounds Targeting the Terminal Respiratory Oxidase, Cytochrome c. Antimicrobial Agents and Chemotherapy, 61(10), e01338-17. https://doi.org/10.1128/AAC.01338-17

Moshabela, M., Bukenya, D., Darong, G., Wamoyi, J., McLean, E., Skovdal, M., … Wringe, A. (2017). Traditional healers, faith healers and medical practitioners: the contribution of medical pluralism to bottlenecks along the cascade of care for HIV/AIDS in Eastern and Southern Africa. Sexually Transmitted Infections, 93(Suppl 3), e052974. https://doi.org/10.1136/sextrans-2016-052974

Mudzengi, D., Sweeney, S., Hippner, P., Kufa, T., Fielding, K., Grant, A. D., … Vassall, A. (2017). The patient costs of care for those with TB and HIV: a cross-sectional study from South Africa. Health Policy and Planning. https://doi.org/10.1093/heapol/czw183

Mwimanzi, F., Toyoda, M., Mahiti, M., Mann, J. K., Martin, J. N., Bangsberg, D., … Ueno, T. (2017). Relative resistance of MHC-B to Nef-mediated downregulation is conserved among primate lentiviruses and influences antiviral T cell responses in HIV-1-infected individuals. Journal of Virology. https://doi.org/10.1128/JVI.01409-17

Naburi, H., Mujinja, P., Kilewo, C., Orsini, N., Bärnighausen, T., Manji, K., … Ekström, A. M. (2017). Job satisfaction and turnover intentions among health care staff providing services for prevention of mother-to-child transmission of HIV in Dar es Salaam, Tanzania. Human Resources for Health, 15, 61. https://doi.org/10.1186/s12960-017-0235-y

Naidoo, V. L., Mann, J. K., Noble, C., Adland, E., Carlson, J. M., Thomas, J., … Ndung’u, T. (2017). Mother-to-Child HIV Transmission Bottleneck Selects for Consensus Virus with Lower Gag-Protease-Driven Replication Capacity. Journal of Virology, 91(17), e00518-17. https://doi.org/10.1128/JVI.00518-17

Ngcapu, S., Theys, K., Libin, P., Marconi, C. V., Sunpath, H., Ndung’u, T., & Gordon, L. M. (2017). Characterization of Nucleoside Reverse Transcriptase Inhibitor-Associated Mutations in the RNase H Region of HIV-1 Subtype C Infected Individuals. Viruses, 9(11). https://doi.org/10.3390/v9110330

Ortblad, K., Kibuuka Musoke, D., Ngabirano, T., Nakitende, A., Magoola, J., Kayiira, P., … Bärnighausen, T. (2017). Direct provision versus facility collection of HIV self-tests among female sex workers in Uganda: A cluster-randomized controlled health systems trial. PLOS Medicine, 14(11), e1002458. https://doi.org/10.1371/journal.pmed.1002458

Paquette, R., Tanton, C., Burns, F., Prah, P., Shahmanesh, M., Field, N., … Mercer, C. H. (2017). Illicit drug use and its association with key sexual risk behaviours and outcomes: Findings from Britain’s third National Survey of Sexual Attitudes and Lifestyles (Natsal-3). PLoS ONE, 12(5), e0177922. https://doi.org/10.1371/journal.pone.0177922

Paredes, R., Tzou, P. L., van Zyl, G., Barrow, G., Camacho, R., Carmona, S., … Shafer, R. W. (2017). Collaborative update of a rule-based expert system for HIV-1 genotypic resistance test interpretation. PLOS ONE, 12(7), e0181357. https://doi.org/10.1371/journal.pone.0181357

Patenaude, B. N., Chimbindi, N., Pillay, D., & Bärnighausen, T. (2017). The impact of ART initiation on household food security over time. Social Science & Medicine. https://doi.org/10.1016/j.socscimed.2017.11.036

Phillips, A. N., Cambiano, V., Nakagawa, F., Revill, P., Jordan, M. R., Hallett, T. B., … Bertagnolio, S. (2017). Cost-effectiveness of public-health policy options in the presence of pretreatment NNRTI drug resistance in sub-Saharan Africa: a modelling study. The Lancet HIV. https://doi.org/10.1016/S2352-3018(17)30190-X

Phillips, A. N., Stover, J., Cambiano, V., Nakagawa, F., Jordan, M. R., Pillay, D., … Bertagnolio, S. (2017). Impact of HIV Drug Resistance on HIV/AIDS-Associated Mortality, New Infections, and Antiretroviral Therapy Program Costs in Sub–Saharan Africa. The Journal of Infectious Diseases, 215(9), 1362–1365. https://doi.org/10.1093/infdis/jix089

Plazy, M., Perriat, D., Gumede, D., Boyer, S., Pillay, D., Dabis, F., Seeley, J., Orne-Gliemann, J. (2017). Implementing universal HIV treatment in a high HIV prevalence and rural South African setting – Field experiences and recommendations of health care providers. PLOS ONE, 12(11), e0186883. https://doi.org/10.1371/journal.pone.0186883

Power, R. A., Tansey, K. E., Buttenschøn, H. N., Cohen-Woods, S., Bigdeli, T., Hall, L. S., … Lewis, C. M. (2017). Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Biological Psychiatry, 81(4), 325–335. https://doi.org/10.1016/j.biopsych.2016.05.010

Price, H., Dunn, D., Zachary, T., Vudriko, T., Chirara, M., Kityo, C., … Gilson, R. (2017). Hepatitis B serological markers and plasma DNA concentrations: baseline results from a treatment-monitoring practices trial. AIDS, 31(8), 1109–1117. https://doi.org/10.1097/QAD.0000000000001454

Ratmann, O., Wymant, C., Colijn, C., Danaviah, S., Essex, M., Frost, S., … on behalf of the PANGEA-HIV Consort. (2017). HIV-1 Full-Genome Phylogenetics of Generalized Epidemics in Sub-Saharan Africa: Impact of Missing Nucleotide Characters in Next-Generation Sequences. AIDS Research and Human Retroviruses. https://doi.org/10.1089/aid.2017.0061

Reimers, P., Israel-Ballard, K., Craig, M., Spies, L., Thior, I., Tanser, F., & Coutsoudis, A. (2017). A Cluster Randomised Trial to Determine the Efficacy of the “Feeding Buddies” Programme in Improving Exclusive Breastfeeding Rates Among HIV-Infected Women in Rural KwaZulu-Natal, South Africa. AIDS and Behavior. https://doi.org/10.1007/s10461-017-1865-8

Reniers, G., Blom, S., Lieber, J., Herbst, A. J., Calvert, C., Bor, J., … Hosegood, V. (2017). Tuberculosis mortality and the male survival deficit in rural South Africa: An observational community cohort study. PLOS ONE, 12(10), e0185692. https://doi.org/10.1371/journal.pone.0185692

Rhee, S.-Y., Varghese, V., Holmes, S. P., Van Zyl, G. U., Steegen, K., Boyd, M. A., … Shafer, R. W. (2017). Mutational Correlates of Virological Failure in Individuals Receiving a WHO-Recommended Tenofovir-Containing First-Line Regimen: An International Collaboration. EBioMedicine, 18(Supplement C), 225–235. https://doi.org/10.1016/j.ebiom.2017.03.024

Rochat, T. J., Houle, B., Stein, A., Pearson, R. M., Newell, M. L., & Bland, R. M. (2017). Cohort Profile: The Siyakhula Cohort, rural South Africa. International Journal of Epidemiology, dyx148-dyx148. https://doi.org/10.1093/ije/dyx148

Rochat, T. J., Stein, A., Cortina-Borja, M., Tanser, F., & Bland, R. M. (2017). The Amagugu intervention for disclosure of maternal HIV to uninfected primary school-aged children in South Africa: a randomised controlled trial. The Lancet HIV. https://doi.org/10.1016/S2352-3018(17)30133-9

Rohr, J. K., Xavier Gómez-Olivé, F., Rosenberg, M., Manne-Goehler, J., Geldsetzer, P., Wagner, R. G., … Bärnighausen, T. (2017). Performance of self-reported HIV status in determining true HIV status among older adults in rural South Africa: a validation study. Journal of the International AIDS Society, 20(1). https://doi.org/10.7448/IAS.20.1.21691

Rosenberg, M. S., Gómez-Olivé, F. X., Rohr, J. K., Houle, B. C., Kabudula, C. W., Wagner, R. G., … Bärnighausen, T. (2017). Sexual Behaviors and HIV Status: A Population-Based Study Among Older Adults in Rural South Africa. JAIDS Journal of Acquired Immune Deficiency Syndromes, 74(1), e9–e17. https://doi.org/10.1097/QAI.0000000000001173

Rossouw, T., Nieuwoudt, M., Manasa, J., Malherbe, G., Lessells, R., Pillay, S., … de Oliveira, T. (2017). HIV drug resistance levels in adults failing first-line antiretroviral therapy in an urban and a rural setting in South Africa. HIV Medicine, 18(2), 104–114. https://doi.org/10.1111/hiv.12400

Sanya, R. E., Tumwesige, E., Elliott, A. M., & Seeley, J. (2017). Perceptions about interventions to control schistosomiasis among the Lake Victoria island communities of Koome, Uganda. PLOS Neglected Tropical Diseases, 11(10), e0005982. https://doi.org/10.1371/journal.pntd.0005982

Schomaker, M., Leroy, V., Wolfs, T., Technau, K.-G., Renner, L., Judd, A., … Davies, M.-A. (2017). Optimal timing of antiretroviral treatment initiation in HIV-positive children and adolescents: a multiregional analysis from Southern Africa, West Africa and Europe. International Journal of Epidemiology, 46(2), 453–465. https://doi.org/10.1093/ije/dyw097

Schultze, A., Paredes, R., Sabin, C., Phillips, A. N., Pillay, D., Mackie, N., … Cozzi-Lepri, A. (2017). The association between detected drug resistance mutations and CD4+ T-cell decline in HIV-positive individuals maintained on a failing treatment regimen. Antiviral Therapy. https://doi.org/10.3851/IMP3178

Seeley, J. (2017). HIV diagnosis increasing in older adults in Europe. The Lancet HIV. https://doi.org/10.1016/S2352-3018(17)30151-0

Shrestha, S., Chihota, V., White, R. G., Grant, A. D., Churchyard, G. J., & Dowdy, D. W. (2017). Impact of Targeted Tuberculosis Vaccination Among a Mining Population in South Africa: A Model-Based Study. American Journal of Epidemiology, 186(12), 1362–1369. https://doi.org/10.1093/aje/kwx192

Siu, G. E., Wight, D., Seeley, J., Namutebi, C., Sekiwunga, R., Zalwango, F., & Kasule, S. (2017). Men’s Involvement in a Parenting Programme to Reduce Child Maltreatment and Gender-Based Violence: Formative Evaluation in Uganda. The European Journal of Development Research. https://doi.org/10.1057/s41287-017-0103-6

Skovdal, M., Wringe, A., Seeley, J., Renju, J., Paparini, S., Wamoyi, J., … Bonnington, O. (2017). Using theories of practice to understand HIV-positive persons varied engagement with HIV services: a qualitative study in six Sub-Saharan African countries. Sexually Transmitted Infections, 93(Suppl 3). https://doi.org/10.1136/sextrans-2016-052977

Ssali, A., Nunn, A., Mbonye, M., Anywaine, Z., & Seeley, J. (2017). Reasons for participating in a randomised clinical trial: The volunteers’ voices in the COSTOP trial in Uganda. Contemporary Clinical Trials Communications, 7(Supplement C), 44–47. https://doi.org/10.1016/j.conctc.2017.05.007

Suthar, A. B., & Bärnighausen, T. (2017). Antiretroviral therapy and population mortality: Leveraging routine national data to advance policy. PLOS Medicine, 14(12), e1002469. https://doi.org/10.1371/journal.pmed.1002469

Suthar, A. B., Nagata, J. M., Nsanzimana, S., Bärnighausen, T., Negussie, E. K., & Doherty, M. C. (2017). Performance-based financing for improving HIV/AIDS service delivery: a systematic review. BMC Health Services Research, 17(1), 6. https://doi.org/10.1186/s12913-016-1962-9

Tanser, F., Bärnighausen, T., Dobra, A., & Sartorius, B. (2017). Identifying ‘corridors of HIV transmission’ in a severely affected rural South African population: a case for a shift toward targeted prevention strategies. International Journal of Epidemiology. https://doi.org/10.1093/ije/dyx257

Tanser, F., Vandormael, A., Cuadros, D., Phillips, A. N., de Oliveira, T., Tomita, A., … Pillay, D. (2017). Effect of population viral load on prospective HIV incidence in a hyperendemic rural African community. Science Translational Medicine, 9(420), eaam8012. https://doi.org/10.1126/scitranslmed.aam8012

Thayyil, S., Oliveira, V., Lally, P. J., Swamy, R., Bassett, P., Chandrasekaran, M., … Shankaran, S. (2017). Hypothermia for encephalopathy in low and middle-income countries (HELIX): study protocol for a randomised controlled trial. Trials, 18(1), 432. https://doi.org/10.1186/s13063-017-2165-3

Thobakgale, C., Naidoo, K., McKinnon, L. R., Werner, L., Samsunder, N., Karim, S. A., … Naidoo, K. (2017). Interleukin 1-Beta (IL-1β) Production by Innate Cells Following TLR Stimulation Correlates With TB Recurrence in ART-Treated HIV-Infected Patients. JAIDS Journal of Acquired Immune Deficiency Syndromes, 74(2). Retrieved from http://journals.lww.com/jaids/Fulltext/2017/02010/Interleukin_1_Beta__IL_1___Production_by_Innate.16.aspx

Titanji, B. K., Pillay, D., & Jolly, C. (2017). Combination antiretroviral therapy and cell–cell spread of wild-type and drug-resistant human immunodeficiency virus-1. Journal of General Virology, 98(4), 821–834. https://doi.org/10.1099/jgv.0.000728

Tlou, B., Sartorius, B., & Tanser, F. (2017). Space-time patterns in maternal and mother mortality in a rural South African population with high HIV prevalence (2000–2014): results from a population-based cohort. BMC Public Health, 17(1). https://doi.org/10.1186/s12889-017-4463-9

Tlou, B., Sartorius, B., & Tanser, F. (2017). Space-time variations in child mortality in a rural South African population with high HIV prevalence (2000–2014). PLOS ONE, 12(8), e0182478. https://doi.org/10.1371/journal.pone.0182478

Tomita, A., Vandormael, A. M., Bärnighausen, T., de Oliveira, T., & Tanser, F. (2017). Social Disequilibrium and the Risk of HIV Acquisition: A Multilevel Study in Rural KwaZulu-Natal Province, South Africa. JAIDS Journal of Acquired Immune Deficiency Syndromes, 75(2), 164–174. https://doi.org/10.1097/QAI.0000000000001349

Tomita, A., Vandormael, A. M., Cuadros, D., Di Minin, E., Heikinheimo, V., Tanser, F., … Burns, J. K. (2017). Green environment and incident depression in South Africa: a geospatial analysis and mental health implications in a resource-limited setting. The Lancet Planetary Health, 1(4), e152–e162. https://doi.org/10.1016/S2542-5196(17)30063-3

Tostevin, A., White, E., Dunn, D., Croxford, S., Delpech, V., Williams, I., … Bradley?Stewart, A. (2017). Recent trends and patterns in HIV?1 transmitted drug resistance in the United Kingdom. HIV Medicine, 18(3), 204–213. https://doi.org/10.1111/hiv.12414

Turbé, V., Gray, E. R., Lawson, V. E., Nastouli, E., Brookes, J. C., Weiss, R. A., … McKendry, R. A. (2017). Towards an ultra-rapid smartphone- connected test for infectious diseases. Scientific Reports, 7(1), 11971. https://doi.org/10.1038/s41598-017-11887-6

van der Heijden, Y. F., Karim, F., Mufamadi, G., Zako, L., Chinappa, T., Shepherd, B. E., … Pym, A. S. (2017). Isoniazid-monoresistant tuberculosis is associated with poor treatment outcomes in Durban, South Africa. The International Journal of Tuberculosis and Lung Disease, 21(6), 670–676. https://doi.org/10.5588/ijtld.16.0843

Vandormael, A., Bärnighausen, T., Herbeck, J., Tomita, A., Phillips, A., Pillay, D., … Tanser, F. (2017). Longitudinal trends in the prevalence of detectable HIV viremia: Population-based evidence from rural KwaZulu-Natal, South Africa. Clinical Infectious Diseases, cix976-cix976. https://doi.org/10.1093/cid/cix976

Vandormael, A., de Oliveira, T., Tanser, F., Bärnighausen, T., & Herbeck, J. T. (2017). High percentage of undiagnosed HIV cases within a hyperendemic South African community: a population-based study. Journal of Epidemiology and Community Health, jech-2017-209713. https://doi.org/10.1136/jech-2017-209713

Vandormael, A., Dobra, A., Bärnighausen, T., de Oliveira, T., & Tanser, F. (2017). Incidence rate estimation, periodic testing and the limitations of the mid-point imputation approach. International Journal of Epidemiology. https://doi.org/10.1093/ije/dyx134

Vassall, A., Siapka, M., Foster, N., Cunnama, L., Ramma, L., Fielding, K., … Sinanovic, E. (2017). Cost-effectiveness of Xpert MTB/RIF for tuberculosis diagnosis in South Africa: a real-world cost analysis and economic evaluation. The Lancet Global Health, 5(7), e710–e719. https://doi.org/10.1016/S2214-109X(17)30205-X

Vollmer, S., Harttgen, K., Alfven, T., Padayachy, J., Ghys, P., & Bärnighausen, T. (2017). The HIV Epidemic in Sub-Saharan Africa is Aging: Evidence from the Demographic and Health Surveys in Sub-Saharan Africa. AIDS and Behavior, 21(1), 101–113. https://doi.org/10.1007/s10461-016-1591-7

Vos, T., Allen, C., Arora, M., Barber, R. M., Bhutta, Z. A., Brown, A., … Murray, C. J. L. (2017). Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1545–1602. https://doi.org/10.1016/S0140-6736(16)31678-6

Walsh, F. J., Bärnighausen, T., Delva, W., Fleming, Y., Khumalo, G., Lejeune, C. L., … Okello, V. (2017). Impact of early initiation versus national standard of care of antiretroviral therapy in Swaziland’s public sector health system: study protocol for a stepped-wedge randomized trial. Trials, 18(1), 383. https://doi.org/10.1186/s13063-017-2128-8

Wong, E. B., Ndung’u, T., & Kasprowicz, V. O. (2017). The role of mucosal-associated invariant T cells in infectious diseases. Immunology, 150(1), 45–54. https://doi.org/10.1111/imm.12673

Wringe, A., Moshabela, M., Nyamukapa, C., Bukenya, D., Ondenge, K., Ddaaki, W., … Renju, J. (2017). HIV testing experiences and their implications for patient engagement with HIV care and treatment on the eve of ‘test and treat’: findings from a multicountry qualitative study. Sexually Transmitted Infections, 93(Suppl 3), e052969. https://doi.org/10.1136/sextrans-2016-052969

Wringe, A., Renju, J., Seeley, J., Moshabela, M., & Skovdal, M. (2017). Bottlenecks to HIV care and treatment in sub-Saharan Africa: a multi-country qualitative study. Sexually Transmitted Infections, 93(Suppl 3), e053172. https://doi.org/10.1136/sextrans-2017-053172

Yadon, A. N., Maharaj, K., Adamson, J. H., Lai, Y.-P., Sacchettini, J. C., Ioerger, T. R., … Pym, A. S. (2017). A comprehensive characterization of PncA polymorphisms that confer resistance to pyrazinamide. Nature Communications, 8(1), 588. https://doi.org/10.1038/s41467-017-00721-2

Yates, T. A., Khan, P. Y., Knight, G. M., Taylor, J. G., McHugh, T. D., Lipman, M., … Abubakar, I. (n.d.). The transmission of Mycobacterium tuberculosis in high burden settings. The Lancet Infectious Diseases, 16(2), 227–238. https://doi.org/10.1016/S1473-3099(15)00499-5

Zhou, B., Bentham, J., Di Cesare, M., Bixby, H., Danaei, G., Cowan, M. J., … Zuñiga Cisneros, J. (n.d.). Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants. The Lancet, 389(10064), 37–55. https://doi.org/10.1016/S0140-6736(16)31919-5

Zhukova, A., Cutino-Moguel, T., Gascuel, O., & Pillay, D. (2017). The Role of Phylogenetics as a Tool to Predict the Spread of Resistance. The Journal of Infectious Diseases, jix411-jix411. https://doi.org/10.1093/infdis/jix411

Zulu, M., Naidoo, K., Mncube, Z., Jaggernath, M., Goulder, P. J., Ndung’u, T., … Thobakgale, C. F. (2017). Reduced Expression of Siglec-7, NKG2A and CD57 on Terminally Differentiated CD56-CD16+ NK Cell Subset is associated with NK Cell Dysfunction in Chronic HIV-1 clade C Infection. AIDS Research and Human Retroviruses. https://doi.org/10.1089/AID.2017.0095

Zuma, T., Wight, D., Rochat, T., & Moshabela, M. (2017). Traditional health practitioners’ management of HIV/AIDS in rural South Africa in the era of widespread antiretroviral therapy. Global Health Action, 10(1), 1352210. https://doi.org/10.1080/16549716.2017.1352210

2016 Publications

Aicken, C. R. H., Fuller, S. S., Sutcliffe, L. J., Estcourt, C. S., Gkatzidou, V., Oakeshott, P., … Shahmanesh, M. (2016). Young people’s perceptions of smartphone-enabled self-testing and online care for sexually transmitted infections: qualitative interview study. BMC Public Health, 16(1), 974. https://doi.org/10.1186/s12889-016-3648-y

Atun, R., Chang, A. Y., Ogbuoji, O., Silva, S., Resch, S., Hontelez, J., & Bärnighausen, T. (2016). Long-term financing needs for HIV control in sub-Saharan Africa in 2015–2050: a modelling study. BMJ Open, 6(3). https://doi.org/10.1136/bmjopen-2015-009656

Barnhart, D., Hertzmark, E., Liu, E., Mungure, E., Muya, A. N., Sando, D., … Spiegelman, D. (2016). Intra-cluster correlation estimates for HIV-related outcomes from care and treatment clinics in Dar es Salaam, Tanzania. Contemporary Clinical Trials Communications, 4, 161–169. https://doi.org/10.1016/j.conctc.2016.09.001

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Oldenburg, C. E., Bärnighausen, T., Tanser, F., Iwuji, C. C., De Gruttola, V., Seage, G. R., … Harling, G. (2016a). Reply to Cohen et al. Clinical Infectious Diseases, 63(12), 1680.2-1680. https://doi.org/10.1093/cid/ciw674

Oldenburg, C. E., Bärnighausen, T., Tanser, F., Iwuji, C. C., De Gruttola, V., Seage, I., George R., … Harling, G. (2016b). Antiretroviral Therapy to Prevent HIV Acquisition in Serodiscordant Couples in a Hyperendemic Community in Rural South Africa. Clinical Infectious Diseases, 63(4), 548–554. https://doi.org/10.1093/cid/ciw335

Oldenburg, C. E., Moscoe, E., & Bärnighausen, T. (2016). Regression Discontinuity for Causal Effect Estimation in Epidemiology. Current Epidemiology Reports, 3(3), 233–241. https://doi.org/10.1007/s40471-016-0080-x

Oldenburg, C. E., Perez-Brumer, A. G., Reisner, S. L., Mayer, K. H., Mimiaga, M. J., Hatzenbuehler, M. L., & Bärnighausen, T. (2016). Human rights protections and HIV prevalence among MSM who sell sex: Cross-country comparisons from a systematic review and meta-analysis. Global Public Health, 1–12. https://doi.org/10.1080/17441692.2016.1149598

Ondenge, K., Renju, J., Bonnington, O., Moshabela, M., Wamoyi, J., Nyamukapa, C., … Skovdal, M. (2017). ‘I am treated well if I adhere to my HIV medication’: putting patient–provider interactions in context through insights from qualitative research in five sub-Saharan African countries. Sexually Transmitted Infections, 93(Suppl 3), e052973. https://doi.org/10.1136/sextrans-2016-052973

Orne-Gliemann, J., Zuma, T., Chikovore, J., Gillespie, N., Grant, M., Iwuji, C., … On Behalf of the TasP Study Group. (2016). Community perceptions of repeat HIV-testing: experiences of the ANRS 12249 Treatment as Prevention trial in rural South Africa. AIDS Care, 28(sup3), 14–23. https://doi.org/10.1080/09540121.2016.1164805

PANGEA_HIV Consortium, ICONIC Project, Yebra, G., Hodcroft, E. B., Ragonnet-Cronin, M. L., Pillay, D., … Kozlakidis, Z. (2016). Using nearly full-genome HIV sequence data improves phylogeny reconstruction in a simulated epidemic. Scientific Reports, 6(1). https://doi.org/10.1038/srep39489

Power, R. A., Parkhill, J., & de Oliveira, T. (2016). Microbial genome-wide association studies: lessons from human GWAS. Nature Reviews Genetics, 18(1), 41–50. https://doi.org/10.1038/nrg.2016.132

Reimers, P., Israel-Ballard, K., Spies, L., Tanser, F., Thior, I., Scott Gordon, W., & Coutsoudis, A. (2016). A Protocol for a Cluster Randomized Trial on the Effect of a “feeding buddy” Program on adherence to the Prevention of Mother-To-Child-Transmission Guidelines in a Rural Area of KwaZulu-Natal, South Africa. JAIDS Journal of Acquired Immune Deficiency Syndromes, 72. Retrieved from http://journals.lww.com/jaids/Fulltext/2016/08011/A_Protocol_for_a_Cluster_Randomized_Trial_on_the.6.aspx

Reniers, G., Wamukoya, M., Urassa, M., Nyaguara, A., Nakiyingi-Miiro, J., Lutalo, T., … Zaba, B. (2016). Data Resource Profile: Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa (ALPHA Network). International Journal of Epidemiology, 45(1), 83–93. https://doi.org/10.1093/ije/dyv343

Renju, J., Moshabela, M., McLean, E., Ddaaki, W., Skovdal, M., Odongo, F., … Wringe, A. (2017). ‘Side effects’ are ‘central effects’ that challenge retention in HIV treatment programmes in six sub-Saharan African countries: a multicountry qualitative study. Sexually Transmitted Infections, 93(Suppl 3), e052971. https://doi.org/10.1136/sextrans-2016-052971

Rochat, T. J., Mitchell, J., Lubbe, A. M., Stein, A., Tomlinson, M., & Bland, R. M. (2017). Communication about HIV and death: Maternal reports of primary school-aged children’s questions after maternal HIV disclosure in rural South Africa. Social Science & Medicine, 172, 124–134. https://doi.org/10.1016/j.socscimed.2016.10.031

Rochat, T. J., Mitchell, J., Stein, A., Mkwanazi, N. B., & Bland, R. M. (2016). The Amagugu Intervention: A Conceptual Framework for Increasing HIV Disclosure and Parent-Led Communication about Health among HIV-Infected Parents with HIV-Uninfected Primary School-Aged Children. Frontiers in Public Health, 4. https://doi.org/10.3389/fpubh.2016.00183

Saini, V., Cumming, B. M., Guidry, L., Lamprecht, D. A., Adamson, J. H., Reddy, V. P., … Steyn, A. J. C. (2016). Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosis. Cell Reports, 14(3), 572–585. https://doi.org/10.1016/j.celrep.2015.12.056

Seo, H. S., Kim, H., Hwang, S. M., Hong, S. H., & Lee, I. Y. (2016). Predictors of job satisfaction and burnout among tuberculosis management nurses and physicians. Epidemiol Health, 38. https://doi.org/10.4178/epih.e2016008

Shahmanesh, M., Schultze, A., Burns, F., Kirk, O., Lundgren, J., Mussini, C., … on behalf of EuroSIDA in EuroCOORD. (2016). The cardiovascular risk management for people living with HIV in Europe: how well are we doing? AIDS, 30(16). Retrieved from http://journals.lww.com/aidsonline/Fulltext/2016/10230/The_cardiovascular_risk_management_for_people.12.aspx

Simoni, Y., Fehlings, M., Kløverpris, H. N., McGovern, N., Koo, S.-L., Loh, C. Y., … Newell, E. W. (2017). Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency. Immunity, 46(1), 148–161. https://doi.org/10.1016/j.immuni.2016.11.005

Surolia, R., Karki, S., Wang, Z., Kulkarni, T., Li, F. J., Vohra, S., … Antony, V. B. (2016). Attenuated heme oxygenase-1 responses predispose the elderly to pulmonary nontuberculous mycobacterial infections. American Journal of Physiology - Lung Cellular and Molecular Physiology, 311(5), L928–L940. https://doi.org/10.1152/ajplung.00397.2015

Sutherland, K. A., Collier, D. A., Claiborne, D. T., Prince, J. L., Deymier, M. J., Goldstein, R. A., … Gupta, R. K. (2016). Wide variation in susceptibility of transmitted/founder HIV-1 subtype C Isolates to protease inhibitors and association with in vitro replication efficiency. Scientific Reports, 6(1). https://doi.org/10.1038/srep38153

The EuroCoord-CHAIN-EPPICC joint project study group, Ngo-Giang-Huong, N., Wittkop, L., Judd, A., Reiss, P., Goetghebuer, T., … Lallemant, M. (2016). Prevalence and effect of pre-treatment drug resistance on the virological response to antiretroviral treatment initiated in HIV-infected children – a EuroCoord-CHAIN-EPPICC joint project. BMC Infectious Diseases, 16(1). https://doi.org/10.1186/s12879-016-1968-2

Tlou, B., Sartorius, B., & Tanser, F. (2016). Spatial-temporal dynamics and structural determinants of child and maternal mortality in a rural, high HIV burdened South African population, 2000–2014: a study protocol. BMJ Open, 6(7), e010013. https://doi.org/10.1136/bmjopen-2015-010013

Treffry-Goatley, A., Lessells, R., Sykes, P., Bärnighausen, T., de Oliveira, T., Moletsane, R., & Seeley, J. (2016). Understanding Specific Contexts of Antiretroviral Therapy Adherence in Rural South Africa: A Thematic Analysis of Digital Stories from a Community with High HIV Prevalence. PLOS ONE, 11(2), e0148801. https://doi.org/10.1371/journal.pone.0148801

van Rooyen, H., Essack, Z., Rochat, T., Wight, D., Knight, L., Bland, R., & Celum, C. (2016). Taking HIV Testing to Families: Designing a Family-Based Intervention to Facilitate HIV Testing, Disclosure, and Intergenerational Communication. Frontiers in Public Health, 4. https://doi.org/10.3389/fpubh.2016.00154

Vandormael, A. M., Boulware, D. R., Tanser, F. C., Bärnighausen, T. W., Stott, K. E., & de Oliveira, T. (2016). Brief Report: Virologic Monitoring Can Be a Cost-Effective Strategy to Diagnose Treatment Failure on First-Line ART. Journal of Acquired Immune Deficiency Syndromes (1999), 71(4), 462–466. https://doi.org/10.1097/QAI.0000000000000870

Wamoyi, J., Renju, J., Moshabela, M., McLean, E., Nyato, D., Mbata, D., … Wringe, A. (2017). Understanding the relationship between couple dynamics and engagement with HIV care services: insights from a qualitative study in Eastern and Southern Africa. Sexually Transmitted Infections, 93(Suppl 3). https://doi.org/10.1136/sextrans-2016-052976

Wang, H., Bhutta, Z. A., Coates, M. M., Coggeshall, M., Dandona, L., Diallo, K., … Murray, C. J. L. (2016). Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1725–1774. https://doi.org/10.1016/S0140-6736(16)31575-6

Wang, H., Naghavi, M., Allen, C., Barber, R. M., Bhutta, Z. A., Carter, A., … Murray, C. J. L. (2016). Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1459–1544. https://doi.org/10.1016/S0140-6736(16)31012-1

Wang, H., Wolock, T. M., Carter, A., Nguyen, G., Kyu, H. H., Gakidou, E., … Murray, C. J. L. (2016). Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980–2015: the Global Burden of Disease Study 2015. The Lancet HIV, 3(8), e361–e387. https://doi.org/10.1016/S2352-3018(16)30087-X

Watters, S. A., Mlcochova, P., Maldarelli, F., Goonetilleke, N., Pillay, D., & Gupta, R. K. (2016). Sequential CCR5-Tropic HIV-1 Reactivation from Distinct Cellular Reservoirs following Perturbation of Elite Control. PLOS ONE, 11(7), e0158854. https://doi.org/10.1371/journal.pone.0158854

White, E., Smit, E., Churchill, D., Collins, S., Booth, C., Tostevin, A., … Dunn, D. T. (2016). No Evidence That HIV-1 Subtype C Infection Compromises the Efficacy of Tenofovir-Containing Regimens: Cohort Study in the United Kingdom. Journal of Infectious Diseases, 214(9), 1302–1308. https://doi.org/10.1093/infdis/jiw213

Yates, T. A., Tanser, F., & Abubakar, I. (2016). Plan Beta for tuberculosis: it’s time to think seriously about poorly ventilated congregate settings. The International Journal of Tuberculosis and Lung Disease, 20(1), 5–10. https://doi.org/10.5588/ijtld.15.0494

Zuma, T., Wight, D., Rochat, T., & Moshabela, M. (2016). The role of traditional health practitioners in Rural KwaZulu-Natal, South Africa: generic or mode specific? BMC Complementary and Alternative Medicine, 16(1). https://doi.org/10.1186/s12906-016-1293-8

June 2023 Publications

Krause, R., Warren, C. M., Simmons, J. D., Rebeiro, P. F., Maruri, F., Karim, F., Sterling, T. R., Koethe, J. R., Leslie, A., & Van Der Heijden, Y. F. (2023). Failure to decrease HbA1c levels following TB treatment is associated with elevated Th1/Th17 CD4+ responses. Frontiers in Immunology, 14, 1151528. https://doi.org/10.3389/fimmu.2023.1151528