Professor Philip Goulder read zoology at Oxford University and then medicine at Cambridge University before specialising in paediatrics. His research centres on mechanisms of immune control of HIV infection in children and adults, on the particular potential for HIV cure/remission in children, and on immune sex differences and their impact on disease outcome. Based at the Peter Medawar Building in Oxford, this work is focused on the HIV epidemic in South Africa through long-term links in Kimberley and in Durban with the Africa Health Research Institute, where Philip holds a faculty position, as well as at the Doris Duke Medical Research Institute at the University of KwaZulu-Natal, and at CAPRISA.
Work at AHRI
Philip’s research focus at AHRI includes paediatric HIV cure, and early-life immune sex differences and their impact on outcomes in responses to vaccines and infections including SARS-CoV-2.
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Selected Recent Publications
Vieira, Vinicius A., et al (2021). Robust HIV-specific CD4+ and CD8+ T-cell responses distinguish the rare phenotype of elite control in adolescents living with HIV from viraemic non-progressors. AIDS.
Youngs, Jonathan, et al (2021). Identification of immune correlates of fatal outcomes in critically ill COVID-19 patients. PLOS Pathogens.
Oxford Immunology Network Covid-19 Response T Cell Consortium, et al (2021). Cell Assays Differentiate Clinical and Subclinical SARS-CoV-2 Infections from Cross-Reactive Antiviral Responses. Nature Communications, vol. 12.
Adland, Emily, et al (2020). Sex-Specific Innate Immune Selection of HIV-1 in Utero Is Associated with Increased Female Susceptibility to Infection . Nature Communications, vol. 11, no. 1.
Millar, Jane R., et al (2020). . High-frequency failure of combination antiretroviral therapy in paediatric HIV infection is associated with unmet maternal needs causing maternal non-adherence. EClinicalMedicine, vol. 22.