Africa Health Research Institute

Wellcome Trust
site visit 2023

Documents

Programme

Programme

View
Biosketches

Biosketches

View
Abstracts

Abstracts

View

Posters

Posters

Sensing of host Interferon-γby Mycobacterium tuberculosis

View
Posters

SARS-CoV2 co-infection modulates immunometabolism of Mycobacterium tuberculosis-infected human macrophages

View
Posters

HIV-1 Gag-protease driven replication capacity impacts cellular inflammation and glucose uptake of T cells.

View
Posters

Beta variant infection combined with vaccination broadens neutralizing immunity against Omicron subvariants

View
Posters

Quantitation of neutrophils and neutrophilassociated proteins in sputum to aid diagnosis of pulmonary TB

View
Posters

Spatial localization of HIV infected macrophages in lymph nodes using multicolor Tissue FAX imaging

View
Posters

Cross-sectional analysis reveals limited genetic diversity in genes that affect integration site targeting (Integrase and Capsid) in acute HIV-1 subtype C infection in South Africa

View
Posters

HIV Escape and Resistance in the Brain: the HERB study pilot phase

View
Posters

Research elected gut biopsies in people living with HIV show cross-compartment specific CD4+T-cell depletion in the upper small intestine

View
Posters

Impact of HIV infection on Intestinal stem cell (ISC) proliferation and differentiation to determine their role during gut homeostasis in people living with HIV

View
Posters

Type 3 ILCs in HIV-infected lymph nodes upregulate inflammatory pathways linked to tissue fibrosis

View
Posters

Can vaccination stop SARS-CoV-2 prolonged infection in people with immunosuppression because of advanced HIV disease?

View
Posters

The impact of HIV on the B-cell responses to SARS-CoV-2 in COVID-19-confirmed cases

View
Posters

Effect of hybrid immunity on the neutralizing antibody response to emerging variants and in people living with HIV.

View
Posters

Localized role for B-cells in the human TB lung.

View
Posters

Clonal Dominance in TCR repertoire of Tissue- Resident memory in CD4+ and CD8+ T cells in Tuberculosis infected Individuals.

View
Posters

Characterization of the naïve B-cell repertoire and antigen-specific B-cell precursors in a South African population to inform the development of germline-targeting HIV immunogens.

View
Posters

Immuno-metabolic profiling of immune cells in Tuberculosis patients.

View
Posters

Assessment of metabolic health of T-cells during TB infection by flow cytometry.

View
Posters

Combination of traditional medicine product (SDK-2) with TNF-a synergistically reactivate latent HIV-1 subtype C in vitro.

View
Posters

Lysophospholipids as mediators of lung inflammation and potential tuberculosis biomarkers.

View
Posters

Discrepancy between Mtb-specific IFNγ and Mtb-specific IgG responses in HIV+ people with low CD4 counts.

View
Posters

Cross-compartment specific changes of innate lymphoid cells in the gut of people living with HIV

View
Posters

Physical characterization of latent tuberculosis lesions from post-mortem human lung tissue

View
Posters

Role of the acid sphingomyelinase pathway in human Mycobacterium tuberculosis pathogenesis.

View
Posters

A New Diagnostic Potential: Novel RNAscope and Immunohistochemistry provides insight in the detection of bacilli in human pulmonary TB tissue samples.

View
Posters

Targeting spleen tyrosine kinase (SYK) for the control of TB-induced granulomatous pathology as a potential host-directed therapy.

View
Posters

T cell immune responses to SARS-CoV-2 and common cold coronaviruses in South African and Zambian COVID-19 convalescent patients

View
Posters

Immune gene spatial profiling of the HIV lymph node reservoir

View
Posters

Targeting M. tuberculosis counteractome to potentiate BCG-induced trained immunity

View
Posters

Potential LTBI biomarkers in ESAT-6 and CFP10 stimulated plasma

View
Posters

Isolation and longitudinal characterization of the development of HIV broadly neutralizing antibodies.

View
Posters

Longitudinal quantification of HIV proviral DNA and host APOBEC3G/-F mRNA expression in cellular subsets that are targeted by HIV-1.

View
Posters

Identification and characterization of HIV viral reservoirs in palatine tonsils from children born with HIV.

View
Posters

The inhibition of Mtb respiratory complexes modulate bioenergetics and metabolome.

View
Posters

Prevalence of curable sexually transmitted infections in a population representative sample of young adults in South Africa.

View
Posters

Association between prior tuberculosis disease and dysglycemia within an HIV-endemic, rural South African population.

View
Posters

Delivery of school-based interventions to promoting adolescent health and well-being: Lessons from a multilevel HIV-prevention intervention through DREAMS in rural KwaZulu-Natal, South Africa

View
Posters

Understanding the uptake of HIV care and prevention and the risk of acquiring and transmitting HIV amongst young women who sell sex in rural KwaZulu-Natal, South Africa

View
Posters

Setting-up a clinical trials unit in rural South Africa: lessons learnt.

View
Posters

What happened to my stock? Management and tracking of HIV selfscreening (HIV-SS) kit distribution in rural KwaZulu-Natal.

View
Posters

Prevalence of Mycobacterium tuberculosis in sputum among adult clinic attendees compared with the surrounding community in rural South Africa: implications for finding the missing millions.

View
Posters

Adaptation, acceptability and feasibility of a shortened Stepping Stones and Creating Futures intervention focused on HIV for young men in rural South Africa.

View
Posters

An electronic Clinical Management System to support peer navigator- social mobilization of youth into decentralised HIV prevention services in rural KwaZulu Natal.

View
Posters

Immunization for Children Living With HIV: A Scoping Review

View
Posters

Correlates of physical activity among people living with and without HIV in rural Uganda.

View
Posters

Common mental health disorders and HIV status among Adolescent Girls and Young Women in rural KwaZulu-Natal.

View
Posters

Investigating the role of social capital and social cohesion in the creation of identity among young women who sell sex in rural KwaZulu-Natal.

View
Posters

Undisclosed antiretroviral therapy use at primary health care clinics in rural KwaZulu-Natal South Africa: A DO-ART Trial Sub-study.

View
Posters

Harnessing the social capital of rural communities for adolescent and youth biosocial HIV prevention: Exploring young people’s experiences and perceptions of a peer navigator intervention in KwaZulu-Natal, South Africa.

View
Posters

Piloting and validating the linkage of routine ART and laboratory records in an HIV endemic setting.

View
Posters

Viral load monitoring in public sector clinics in rural South Africa

View
Posters

Population shifts in detectable HIV viral load in rural KwaZulu-Natal.

View
Posters

Responsible drug advertising: An investigation into the marketing and promotion of Covid-19 preparations on social media in KwaZulu-Natal.

View
Posters

“It felt like a weight was being taken off of my shoulders”: The impact of Lending a hand intervention in supporting migrant adolescents and young people, in KwaZulu-Natal, South Africa.

View
Posters

Barriers and facilitators of tailored HIV prevention and community based sexual and reproductive health intervention: perspectives from the Isisekelo Sempilo Clinical Trial Process Evaluation in rural KZN, South Africa.

View
Posters

Covid-19 and older people’s wellbeing in northern KwaZulu-Natal – the importance of relationships.

View
Posters

Barriers, facilitators and opportunities for successful blood pressure control among people with hypertension in rural KwaZulu-Natal: Preparation for the IMPACT-BP Trial

View
Posters

Examining Emerging Key Ethical Issues in the Planning, Review, and Implementation of Covid-19 Research in Africa, and the Preparedness and Responsiveness of Research Review Authorities.

View
Posters

Infecting Minds: The Past, present, and future of Vaccine hesitancy in South Africa.

View
Posters

Perceptions and experiences of young people adhering and not adhering to Highly Active Antiretroviral Therapy in sub-Saharan Africa: a scoping review.

View
Posters

Agency among young people living with HIV in urban and rural KwaZulu-Natal.

View
Posters

Progress toward discovering and testing whole blood transcriptomic correlates of protection in a human cohort.

View
Posters

An evaluation of a combined psychological and parenting intervention for HIV-positive women depressed in the perinatal period, to enhance child development and reduce maternal depression: Study Protocol for the Insika Yomama Cluster Randomised Controlled Trial.

View
Posters

Process evaluation: Understanding the implementation and adaptation of a peerled intervention to deliver biosocial HIV prevention for adolescents and youth in rural South Africa.

View
Posters

The feasibility and acceptability of a combined therapy package for maternal depression and parenting adapted for telephonic delivery in a rural, low-income HIV-positive population in South Africa during Covid-19 – A Qualitative Investigation.

View
Posters

Interrupted time series analysis to assess the impact of Covid-19 on M. tuberculosis transmission in uMkhanyakude district.

View
Posters

Prevalence of curable sexually transmitted infections amongst female sex workers in rural KwaZulu-Natal.

View
Posters

Features of symptomatic and asymptomatic prevalant TB in an HIV endemic rural South African district.

View
Posters

Sexual and reproductive health needs of school-going children in the context of Covid-19 in rural KwaZulu-Natal, South Africa.

View
Posters

Economic, Social, and Demographic impacts of drought on treatment adherence among people living with HIV in rural South Africa.

View
Posters

Quantifying met and unmet health needs for HIV, hypertension and diabetes in rural KwaZulu-Natal, South Africa.

View
Posters

Next generation HIV-1 sequencing reveals complex patterns of drug resistance and transmission in a rural African setting

View